采用高频密码子分析法,对人参属药用植物人参(Panax ginseng C.A.Mey.)和三七[PanaxNotoginseng(Burk.)F.H.Chen]的蛋白质编码基因序列(coding DNA sequence,CDS)进行了同义密码子相对使用频率(relative frequency of synonymous coden,...采用高频密码子分析法,对人参属药用植物人参(Panax ginseng C.A.Mey.)和三七[PanaxNotoginseng(Burk.)F.H.Chen]的蛋白质编码基因序列(coding DNA sequence,CDS)进行了同义密码子相对使用频率(relative frequency of synonymous coden,RFSC)分析,确定了人参高频密码子6个和三七高频密码子7个。将人参和田七的密码子使用频率进行比较,结果显示两者的密码子偏爱性具有较高的一致性。分析结果为外源基因在人参和三七中的表达提供参考。展开更多
Panax japonicus, which in the Tujia dialect is known as "Baisan Qi" and "Zhujieshen", is a classic "qi" drug of Tujia ethnomedicine and it has unique effects on disease caused by "qi...Panax japonicus, which in the Tujia dialect is known as "Baisan Qi" and "Zhujieshen", is a classic "qi" drug of Tujia ethnomedicine and it has unique effects on disease caused by "qi" stagnation and blood stasis.This paper serves as the basis of further scientific research and development of Panax japonicus. The pharmacology effects of molecular pharmacology were discussed and summarized. P. japonicus plays an important role on several diseases, such as rheumatic arthritis, cancer, cardiovascular agents, and this review provides new insights into P. japonicus as promising agents to substitute ginseng and notoginseng.展开更多
文摘采用高频密码子分析法,对人参属药用植物人参(Panax ginseng C.A.Mey.)和三七[PanaxNotoginseng(Burk.)F.H.Chen]的蛋白质编码基因序列(coding DNA sequence,CDS)进行了同义密码子相对使用频率(relative frequency of synonymous coden,RFSC)分析,确定了人参高频密码子6个和三七高频密码子7个。将人参和田七的密码子使用频率进行比较,结果显示两者的密码子偏爱性具有较高的一致性。分析结果为外源基因在人参和三七中的表达提供参考。
基金financially supported by Natural Science Foundation of Hunan Province (No. 2017JJ5041, 2018JJ2293)the National Key R&D Program of China (No. 2018YFC1707900)+1 种基金National Natural Science Foundation of China (No. 81703819, 81874369, 81803708, 81673579 and 81374062)Key Research and Development Programs of Hunan Science and Technology Department (No. 2018SK2113, 2018SK2119, 2018WK2081)。
文摘Panax japonicus, which in the Tujia dialect is known as "Baisan Qi" and "Zhujieshen", is a classic "qi" drug of Tujia ethnomedicine and it has unique effects on disease caused by "qi" stagnation and blood stasis.This paper serves as the basis of further scientific research and development of Panax japonicus. The pharmacology effects of molecular pharmacology were discussed and summarized. P. japonicus plays an important role on several diseases, such as rheumatic arthritis, cancer, cardiovascular agents, and this review provides new insights into P. japonicus as promising agents to substitute ginseng and notoginseng.