The Orf disease, also known as contagious ecthyma, is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects small ruminants such as sheep and goats. It is transmitted to humans through cont...The Orf disease, also known as contagious ecthyma, is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects small ruminants such as sheep and goats. It is transmitted to humans through contact with an infected animal or fomites. Human infection typically is associated with occupational animal contact. We recently treated a healthy 41-year-old woman who presented a hangnail lesion on the middle finger of her right hand. The lesion was hard cauliflower-like mass, granulomatous and painful. Surgical debridement and biopsy were performed for further investigation. The Orf disease is usually self-limiting and resolves in 6 - 10 weeks, but complications may occur. The diagnosis may be confirmed by electron microscopy, conventional histopathology or by isolation of the virus by PCR. Early clinical recognition and knowledge of this benign viral condition are vital to avoid unnecessary surgical intervention.展开更多
文摘The Orf disease, also known as contagious ecthyma, is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects small ruminants such as sheep and goats. It is transmitted to humans through contact with an infected animal or fomites. Human infection typically is associated with occupational animal contact. We recently treated a healthy 41-year-old woman who presented a hangnail lesion on the middle finger of her right hand. The lesion was hard cauliflower-like mass, granulomatous and painful. Surgical debridement and biopsy were performed for further investigation. The Orf disease is usually self-limiting and resolves in 6 - 10 weeks, but complications may occur. The diagnosis may be confirmed by electron microscopy, conventional histopathology or by isolation of the virus by PCR. Early clinical recognition and knowledge of this benign viral condition are vital to avoid unnecessary surgical intervention.
