Trans-neuronal viral tracing is becoming one of the most important methods for mapping neuronal circuit connections,but an anterograde trans-synaptic tracer compatible with functional assays is still lacking.Adeno-ass...Trans-neuronal viral tracing is becoming one of the most important methods for mapping neuronal circuit connections,but an anterograde trans-synaptic tracer compatible with functional assays is still lacking.Adeno-associated virus(AAV)is replication-defective,and its production of offspring needs the help of adenovirus(AV)[1]or herpesvirus co-infection[2].The replication deficiency,non-pathogenicity,easy manipulability,展开更多
文摘Trans-neuronal viral tracing is becoming one of the most important methods for mapping neuronal circuit connections,but an anterograde trans-synaptic tracer compatible with functional assays is still lacking.Adeno-associated virus(AAV)is replication-defective,and its production of offspring needs the help of adenovirus(AV)[1]or herpesvirus co-infection[2].The replication deficiency,non-pathogenicity,easy manipulability,