Airborne diseases including SARS,bird flu,and the ongoing Coronavirus Disease 2019(COVID-19)have stimulated the demand for developing novel bioassay methods competent for early-stage diagnosis and large-scale screenin...Airborne diseases including SARS,bird flu,and the ongoing Coronavirus Disease 2019(COVID-19)have stimulated the demand for developing novel bioassay methods competent for early-stage diagnosis and large-scale screening.Here,we briefly summarize the state-of-the-art methods for the detection of infectious pathogens and discuss key challenges.We highlight the trend for next-generation technologies benefiting from multidisciplinary advances in microfabrication,nanotechnology and synthetic biology,which allow sensitive,rapid yet inexpensive pathogen assays with portable intelligent device.展开更多
基金This work was financially supported by the National Natural Science Foundation of China(21991134,91953106)Science Foundation of the Shanghai Municipal Science and Technology Commission(19JC1410300,21dz2210100)。
文摘Airborne diseases including SARS,bird flu,and the ongoing Coronavirus Disease 2019(COVID-19)have stimulated the demand for developing novel bioassay methods competent for early-stage diagnosis and large-scale screening.Here,we briefly summarize the state-of-the-art methods for the detection of infectious pathogens and discuss key challenges.We highlight the trend for next-generation technologies benefiting from multidisciplinary advances in microfabrication,nanotechnology and synthetic biology,which allow sensitive,rapid yet inexpensive pathogen assays with portable intelligent device.
