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Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells 被引量:1
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作者 Daisuke Hisamatsu Hayato Naka-Kaneda 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第11期1746-1747,共2页
Regenerative medicine by cell transplantation is a novel therapy for treating end-stage organ failure and tissue damage. Cell-based therapy based on the transplantation of neural stem/progenitor cells (NSPCs) repres... Regenerative medicine by cell transplantation is a novel therapy for treating end-stage organ failure and tissue damage. Cell-based therapy based on the transplantation of neural stem/progenitor cells (NSPCs) represents an attractive strategy for the treatment of neurodegenerative diseases, but obtaining large numbers of these cells is difficult and their differentiation potential is strictly restricted in a spatiotemporally-regulated manner during central nervous system (CNS) development. Therefore, embryonic stem cells and induced pluripotent stem cells represent an attractive alternative for cell-transplantation therapy in regenerative medicine. 展开更多
关键词 cell stem Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells MSCs SASP
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