Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hy...Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hyperplasia (BPH) patients scheduled for transurethral resection of the prostate (TURP) under general anesthesia with laryngeal mask airway (LMA) were randomly divided into groups F and S. Group F (n=30) received PCIA device with fentanyl 10 μg/kg+8 mg ondansetron, and Group S (n=30) received placebo (PCIA device with 8 mg ondansetron). The visual analog scale (VAS) scores for pain were evaluated at 0, 2, 4, 8, 16, 24, and 48 h by the same staff. And recorded were incidence of cystospasm, side effects, application of hemostatic, duration of drawing Foley catheter and continuous bladder irrigation, time of exhaust after operation, time of post-operative stay and cost of hospitalization. Results: The incidence of cystospasm in Group F was significantly lower than that in Group S in the 48 h after operation (P<0.05), the VAS scores for pain in Group F was significantly lower than that in Group S within the 48 h after operation (P<0.01). The time of exhaust after operation in Group F was significantly later than in Group S (P<0.05). No significant difference was observed in applications of hemostatic, duration of drawing Foley catheter, duration of continuous bladder irrigation, time of post-operative stay and cost of hospitalization between the 2 groups. Conclusion: PCIA with fentanyl (10 μg/kg) relieves pain with little side effect and reduces cystospasm satisfactorily.展开更多
目的观察腹横肌平面阻滞(TAPB)联合患者自控静脉镇痛(PCIA)对脾切除术后镇痛的效果.方法采用回顾性研究方法,选择2021年1月至12月在南昌市第九医院普外科行脾切除+贲门周围血管离断术的63例患者作为研究对象.根据术后镇痛技术的不同将...目的观察腹横肌平面阻滞(TAPB)联合患者自控静脉镇痛(PCIA)对脾切除术后镇痛的效果.方法采用回顾性研究方法,选择2021年1月至12月在南昌市第九医院普外科行脾切除+贲门周围血管离断术的63例患者作为研究对象.根据术后镇痛技术的不同将患者分为TAPB联合PCIA组(33例)和单纯PICA组(30例),比较两组术后镇痛效果的差异.结果两组患者性别、年龄、身高、体质量和术前Child-Pugh分级、美国麻醉医师协会(ASA)分级等比较差异均无统计学意义.TAPB联合PCIA组手术时间、术中出血量、术中输血量均较单纯PICA组有所增加[手术时间(min):85.0(32.5)比82.5(40.0),术中出血量(mL):500(300)比425(500),术中输血量(mL):400(300)比300(525)],术后腹腔感染和切口感染发生率均较单纯PICA组有降低趋势[腹腔感染:18.2%(6/33)比20.0%(6/30),切口感染:21.2%(7/330)比23.3%(7/30)],但两组比较差异均无统计学意义(均P>0.05).随时间延长,两组视觉模拟评分(VAS)均逐渐降低,TAPB联合PCIA组术后6、12、24、48、72 h VAS均明显低于单纯PICA组[分:4.0(1.0)比6.0(3.0)、3.0(2.0)比4.0(2.0)、2.0(1.5)比3.5(1.5),1.0(1.0)比2.0(1.5)、1.0(1.0)比2.0(2.0),均P<0.05],PCIA按压总次数较单纯PICA组明显减少(次:2.64±1.19比3.67±1.67,P<0.05).结论TAPB联合PCIA对脾切除断流术后患者的镇痛效果优于单纯PCIA.展开更多
文摘Objective: To evaluate the clinical efficacy and safety of patient-controlled intravenous analgesia (PCIA) with fentanyl for cystospasm after transurethral resection of the prostate. Methods: Sixty benign prostatic hyperplasia (BPH) patients scheduled for transurethral resection of the prostate (TURP) under general anesthesia with laryngeal mask airway (LMA) were randomly divided into groups F and S. Group F (n=30) received PCIA device with fentanyl 10 μg/kg+8 mg ondansetron, and Group S (n=30) received placebo (PCIA device with 8 mg ondansetron). The visual analog scale (VAS) scores for pain were evaluated at 0, 2, 4, 8, 16, 24, and 48 h by the same staff. And recorded were incidence of cystospasm, side effects, application of hemostatic, duration of drawing Foley catheter and continuous bladder irrigation, time of exhaust after operation, time of post-operative stay and cost of hospitalization. Results: The incidence of cystospasm in Group F was significantly lower than that in Group S in the 48 h after operation (P<0.05), the VAS scores for pain in Group F was significantly lower than that in Group S within the 48 h after operation (P<0.01). The time of exhaust after operation in Group F was significantly later than in Group S (P<0.05). No significant difference was observed in applications of hemostatic, duration of drawing Foley catheter, duration of continuous bladder irrigation, time of post-operative stay and cost of hospitalization between the 2 groups. Conclusion: PCIA with fentanyl (10 μg/kg) relieves pain with little side effect and reduces cystospasm satisfactorily.
文摘目的观察腹横肌平面阻滞(TAPB)联合患者自控静脉镇痛(PCIA)对脾切除术后镇痛的效果.方法采用回顾性研究方法,选择2021年1月至12月在南昌市第九医院普外科行脾切除+贲门周围血管离断术的63例患者作为研究对象.根据术后镇痛技术的不同将患者分为TAPB联合PCIA组(33例)和单纯PICA组(30例),比较两组术后镇痛效果的差异.结果两组患者性别、年龄、身高、体质量和术前Child-Pugh分级、美国麻醉医师协会(ASA)分级等比较差异均无统计学意义.TAPB联合PCIA组手术时间、术中出血量、术中输血量均较单纯PICA组有所增加[手术时间(min):85.0(32.5)比82.5(40.0),术中出血量(mL):500(300)比425(500),术中输血量(mL):400(300)比300(525)],术后腹腔感染和切口感染发生率均较单纯PICA组有降低趋势[腹腔感染:18.2%(6/33)比20.0%(6/30),切口感染:21.2%(7/330)比23.3%(7/30)],但两组比较差异均无统计学意义(均P>0.05).随时间延长,两组视觉模拟评分(VAS)均逐渐降低,TAPB联合PCIA组术后6、12、24、48、72 h VAS均明显低于单纯PICA组[分:4.0(1.0)比6.0(3.0)、3.0(2.0)比4.0(2.0)、2.0(1.5)比3.5(1.5),1.0(1.0)比2.0(1.5)、1.0(1.0)比2.0(2.0),均P<0.05],PCIA按压总次数较单纯PICA组明显减少(次:2.64±1.19比3.67±1.67,P<0.05).结论TAPB联合PCIA对脾切除断流术后患者的镇痛效果优于单纯PCIA.