Copyright 2024,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com.Aims and Scope.Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(...Copyright 2024,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com.Aims and Scope.Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(meta-analysis,systematic review)and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.展开更多
Background:Human telomerase reverse transcriptase(hTERT)and its components play a significant role in cancer progression,but recent data demonstrated that telomeres and telomerase alterations could be found in other d...Background:Human telomerase reverse transcriptase(hTERT)and its components play a significant role in cancer progression,but recent data demonstrated that telomeres and telomerase alterations could be found in other diseases;increasing evidence suggests a key role of this enzyme in the fields of hepatobiliary and pancreatic diseases.Data sources:We performed a PubMed search with the following keywords:telomerase,hepatocellular carcinoma,cholangiocarcinoma,pancreatic adenocarcinoma by December 2019.We reviewed the relevant publications that analyzed the correlation between telomerase activity and hepatobiliary and pancreatic diseases.Results:Telomerase reactivation plays a significant role in the development and progression of hepatobiliary and pancreatic tumors and could be used as a diagnostic biomarker for hepatobiliary and pancreatic cancers,as a predictor for prognosis and a promising therapeutic target.Conclusions:Our review summarized the evidence about the critical role of hTERT in cancerous and precancerous lesions of the alteration and its activity in hepatobiliary and pancreatic diseases.展开更多
BACKGROUND: Total parenteral nutrition (TPN) has been recognized as the mainstay of nutritional support in patients with severe hepatopancreatobiliary (HPB) diseases for decades. However, recent studies advocate the u...BACKGROUND: Total parenteral nutrition (TPN) has been recognized as the mainstay of nutritional support in patients with severe hepatopancreatobiliary (HPB) diseases for decades. However, recent studies advocate the utilization of endoscopic nasojejunal feeding tube placement (ENFTP), rather than the conventional approach. This study was designed to compare the clinical value of ENFTP and TPN in patients with severe HPB diseases. METHODS: Two groups of patients with severe HPB diseases were analyzed retrospectively. One group of 88 patients received ENFTP, and the other 96 received TPN. Routine blood levels, serum glucose and prealbumin, hepatic and renal function, serum lipid, and calcium were measured at baseline and after 1, 2, and 4 weeks of nutritional support. Also, complication rate, mortality, nutritional support time, mechanical ventilation time, mean length of time in intensive care unit, and duration of hospital stay were analyzed. RESULTS: After 4 weeks of nutritional support, the degree of recovery of red blood cells, prealbumin, and blood glucose was greater in the ENFTP than in the TPN group (P<0.05). Furthermore, the ENFTP group showed a lower incidence of septicemia, multiple organ dysfunction syndrome, peripancreatic infection, biliary infection, and nosocomial infection, in addition to shorter nutritional support time and hospital stay (P<0.05). CONCLUSIONS: ENFTP is much more effective than TPN in assisting patients with severe HPB diseases to recover from anemia, low prealbumin level, and high serum glucose, as well as in decreasing the rates of various infections (pulmonary infection excluded), multiple organ dysfunction syndrome rate, nutrition support time, and length of hospital stay. Therefore, ENFTP is safer and more economical for clinical application.展开更多
Hepatobiliary & Pancreatic Diseases International (HBPD INT) is a journal published bimonthly in English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welco...Hepatobiliary & Pancreatic Diseases International (HBPD INT) is a journal published bimonthly in English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original展开更多
Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome...Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:展开更多
Hepatobiliary & Pancreatic Diseases International(HBPD Int)is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hang-zhou,China.We welcome ori...Hepatobiliary & Pancreatic Diseases International(HBPD Int)is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hang-zhou,China.We welcome original articles fromany part of the world;no charge is made for re-view.The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers,then either accepted for publi-cation or rejected by the Editor.Please send allsubmissions to:The EditorHepatobiliary & Pancreatic Diseases International(HBPD Int),First Affiliated Hospital,ZhejiangUniversity School of Medicine,79 Qingchun Road,展开更多
Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome...Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:The EditorHopatobiliary & Pancreatic Diseases International(HBPD Int), First Affiliated Hospital, Zhejiang展开更多
Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome...Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:展开更多
General information Hepatobiliary & Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Ch...General information Hepatobiliary & Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers, then either accepted for publication or rejected by the chief editor.展开更多
Chief Editor:Shu-Sen Zheng,MD,PhD Ihdexed/abstracted by SCI-E,IM/MEDLINE,CA,EM Impact factor:1.649(ISI 2016 JCR)Manuscript Online Submission to:http://mc03.manuscriptcentral.com/hbpdint Look for HBPD INT both in print...Chief Editor:Shu-Sen Zheng,MD,PhD Ihdexed/abstracted by SCI-E,IM/MEDLINE,CA,EM Impact factor:1.649(ISI 2016 JCR)Manuscript Online Submission to:http://mc03.manuscriptcentral.com/hbpdint Look for HBPD INT both in print and online.Available in a variety of disciplines,this journal keeps busy professionals up to date on information that will affect their practice.展开更多
Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surg...Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torials, Reviews, Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in thefield of the submitted paper. For detailed instruc-tions concerning the submission of manuscripts,展开更多
Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surg...Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torials, Reviews, Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in the展开更多
Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surg...Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torias, Reviews , Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in the展开更多
Copyright 2010,Hepatobiliary & Pancreatic Diseases International. All rights reserved.www.hbpdint.com General information Hepatobiliary & Pancreatic Diseases International (HBPD INT)
Hepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in English language by the First Af- filiated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original ...Hepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in English language by the First Af- filiated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers, then either accepted for publication or rejected by the chief editor.展开更多
Copyright 2014,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.comGeneral information Hepatobiliary&Pancreatic Diseases International(HBPD INT)is a journal published bimonthly i...Copyright 2014,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.comGeneral information Hepatobiliary&Pancreatic Diseases International(HBPD INT)is a journal published bimonthly in English language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,China.We welcome original research articles,review articles,editorials,and others from any part of the world.Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,then either accepted for publication展开更多
General informationHepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China....General informationHepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer review- ers, then either accepted for publication or rejected by the chief editor.展开更多
Copyright 2021,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(...Copyright 2021,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(meta-analysis,systematic review)and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.展开更多
Copyright 2021, Hepatobiliary & Pancreatic Diseases International. All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary & Pancreatic Diseases International publishes peer-reviewed original papers, ...Copyright 2021, Hepatobiliary & Pancreatic Diseases International. All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary & Pancreatic Diseases International publishes peer-reviewed original papers, reviews(meta-analysis, systematic review) and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.展开更多
文摘Copyright 2024,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com.Aims and Scope.Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(meta-analysis,systematic review)and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.
文摘Background:Human telomerase reverse transcriptase(hTERT)and its components play a significant role in cancer progression,but recent data demonstrated that telomeres and telomerase alterations could be found in other diseases;increasing evidence suggests a key role of this enzyme in the fields of hepatobiliary and pancreatic diseases.Data sources:We performed a PubMed search with the following keywords:telomerase,hepatocellular carcinoma,cholangiocarcinoma,pancreatic adenocarcinoma by December 2019.We reviewed the relevant publications that analyzed the correlation between telomerase activity and hepatobiliary and pancreatic diseases.Results:Telomerase reactivation plays a significant role in the development and progression of hepatobiliary and pancreatic tumors and could be used as a diagnostic biomarker for hepatobiliary and pancreatic cancers,as a predictor for prognosis and a promising therapeutic target.Conclusions:Our review summarized the evidence about the critical role of hTERT in cancerous and precancerous lesions of the alteration and its activity in hepatobiliary and pancreatic diseases.
文摘BACKGROUND: Total parenteral nutrition (TPN) has been recognized as the mainstay of nutritional support in patients with severe hepatopancreatobiliary (HPB) diseases for decades. However, recent studies advocate the utilization of endoscopic nasojejunal feeding tube placement (ENFTP), rather than the conventional approach. This study was designed to compare the clinical value of ENFTP and TPN in patients with severe HPB diseases. METHODS: Two groups of patients with severe HPB diseases were analyzed retrospectively. One group of 88 patients received ENFTP, and the other 96 received TPN. Routine blood levels, serum glucose and prealbumin, hepatic and renal function, serum lipid, and calcium were measured at baseline and after 1, 2, and 4 weeks of nutritional support. Also, complication rate, mortality, nutritional support time, mechanical ventilation time, mean length of time in intensive care unit, and duration of hospital stay were analyzed. RESULTS: After 4 weeks of nutritional support, the degree of recovery of red blood cells, prealbumin, and blood glucose was greater in the ENFTP than in the TPN group (P<0.05). Furthermore, the ENFTP group showed a lower incidence of septicemia, multiple organ dysfunction syndrome, peripancreatic infection, biliary infection, and nosocomial infection, in addition to shorter nutritional support time and hospital stay (P<0.05). CONCLUSIONS: ENFTP is much more effective than TPN in assisting patients with severe HPB diseases to recover from anemia, low prealbumin level, and high serum glucose, as well as in decreasing the rates of various infections (pulmonary infection excluded), multiple organ dysfunction syndrome rate, nutrition support time, and length of hospital stay. Therefore, ENFTP is safer and more economical for clinical application.
文摘Hepatobiliary & Pancreatic Diseases International (HBPD INT) is a journal published bimonthly in English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original
文摘Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:
文摘Hepatobiliary & Pancreatic Diseases International(HBPD Int)is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hang-zhou,China.We welcome original articles fromany part of the world;no charge is made for re-view.The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers,then either accepted for publi-cation or rejected by the Editor.Please send allsubmissions to:The EditorHepatobiliary & Pancreatic Diseases International(HBPD Int),First Affiliated Hospital,ZhejiangUniversity School of Medicine,79 Qingchun Road,
文摘Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:The EditorHopatobiliary & Pancreatic Diseases International(HBPD Int), First Affiliated Hospital, Zhejiang
文摘Hepatobiliary & Pancreatic Diseases International(HBPD Int) is a journal published quarterly inEnglish language by the First Affiliated Hospital,Zhejiang University School of Medicine, Hang-zhou, China. We welcome original articles fromany part of the world; no charge is made for re-view. The papers are reviewed by members of theEditorial Board and our international panel of ex-pert peer reviewers, then either accepted for publi-cation or rejected by the Editor. Please send allsubmissions to:
文摘General information Hepatobiliary & Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers, then either accepted for publication or rejected by the chief editor.
文摘Chief Editor:Shu-Sen Zheng,MD,PhD Ihdexed/abstracted by SCI-E,IM/MEDLINE,CA,EM Impact factor:1.649(ISI 2016 JCR)Manuscript Online Submission to:http://mc03.manuscriptcentral.com/hbpdint Look for HBPD INT both in print and online.Available in a variety of disciplines,this journal keeps busy professionals up to date on information that will affect their practice.
文摘Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torials, Reviews, Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in thefield of the submitted paper. For detailed instruc-tions concerning the submission of manuscripts,
文摘Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torials, Reviews, Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in the
文摘Aims and ScopeHBPD Int publishes peer-reviewed original papers,reviews and editorials concerned with clinical prac-tice and research in the fields of hepatobiliary andpancreatic diseases. Papers cover the medical,surgical, radiological, pathological, biochemical,physiological and historical aspects of the subjectareas under the headings Liver, Biliary, Pancreas,Transplantation, Research, Special Reports, Edi-torias, Reviews , Brief Communications and CaseReports. The journal also deals with the basic sci-ences and experimental work. All submitted papersare reviewed by at least two referees expert in the
文摘Copyright 2010,Hepatobiliary & Pancreatic Diseases International. All rights reserved.www.hbpdint.com General information Hepatobiliary & Pancreatic Diseases International (HBPD INT)
文摘Hepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in English language by the First Af- filiated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers, then either accepted for publication or rejected by the chief editor.
文摘Copyright 2014,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.comGeneral information Hepatobiliary&Pancreatic Diseases International(HBPD INT)is a journal published bimonthly in English language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,China.We welcome original research articles,review articles,editorials,and others from any part of the world.Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,then either accepted for publication
文摘General informationHepatobiliary ＆ Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. We welcome original research articles, review articles, editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer review- ers, then either accepted for publication or rejected by the chief editor.
文摘Copyright 2021,Hepatobiliary&Pancreatic Diseases International.All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary&Pancreatic Diseases International publishes peerreviewed original papers,reviews(meta-analysis,systematic review)and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.
文摘Copyright 2021, Hepatobiliary & Pancreatic Diseases International. All rights reserved.www.hbpdint.com Aims and Scope Hepatobiliary & Pancreatic Diseases International publishes peer-reviewed original papers, reviews(meta-analysis, systematic review) and editorials concerned with clinical practice and research in the fields of hepatobiliary and pancreatic diseases.
