Objective: To investigate the changes in the hypothalamic metabolites of lipopolysaccharide(LPS) febrile young rabbits after the treatment with pediatric tuina.Methods: A total of 30 young rabbits were randomly assign...Objective: To investigate the changes in the hypothalamic metabolites of lipopolysaccharide(LPS) febrile young rabbits after the treatment with pediatric tuina.Methods: A total of 30 young rabbits were randomly assigned into three groups: the normal group, the model group, and the tuina group. Both the model group and the tuina group were injected intravenously with LPS. “Six antipyretic manipulations”(pushing Tianmen, pushing Kangong, kneading Taiyang,kneading Erhougaogu, clearing Tianheshui, and pushing Jizhu) were administered 1 h after the LPS injection in the tuina group. The rectal temperatures of the young rabbits were monitored during the experiment to explore the antipyretic effect. Three hours after the injection, the content of interleukin-1β(IL-1β), tumor necrosis factor(TNF)-a, and prostaglandin E;(PGE;) in the serum was detected. In addition, liquid chromatography-mass spectrometry(LC-MS) was used for the hypothalamus metabolomics.Results: Compared with the model group, the rectal temperature of the tuina group was decreased at 2 h and 3 h after the LPS injection(P =.04, P =.03, respectively), and the content of IL-1β, TNF-a, and PGE2was decreased(P =.03, P =.003, and P =.008, respectively). The metabolomics results showed that there were 23 potential biomarkers after the tuina intervention, enriching 27 pathways. Lipid metabolites,especially glycerophospholipids, were a majority of the altered metabolites. The primary metabolic pathways affected by tuina included the arachidonic acid metabolism, the GABAergic synapse, D-glutamine and D-glutamate metabolism, and the glutamatergic synapse.Conclusion: Pediatric tuina reduced the temperature of the febrile rabbits and downregulated the expression of IL-1β, TNF-a, and PGE2, and the antipyretic mechanism may be related to changes in metabolites and metabolic pathways in the hypothalamus.展开更多
This paper describes the similarities and differences between three-character scripture school from Shandong, Shanghai pediatric massage and Hunan Liu Kaiyun pediatric massage in the treatment of Recurrent respiratory...This paper describes the similarities and differences between three-character scripture school from Shandong, Shanghai pediatric massage and Hunan Liu Kaiyun pediatric massage in the treatment of Recurrent respiratory tract in order to standardize operation, collect references and provide the basis for local infantile massage school.展开更多
Objective:To systematically evaluate the clinical effect of pediatric massage on chronic persistent asthma in children.Methods:We searched relevant literatures through PubMed database,Embase database,Cochrane library,...Objective:To systematically evaluate the clinical effect of pediatric massage on chronic persistent asthma in children.Methods:We searched relevant literatures through PubMed database,Embase database,Cochrane library,Wanfang database,CNKI and VIP database to screen randomized controlled trials that met the inclusion criteria.According to Cochrane bias risk assessment criteria,the quality of the included literature was evaluated.Finally,Stata 15.1 software was used to analyze the extracted data.Results:A total of 18 studies,1656 participants were included in our Meta analysis.The pooled results showed that pediatric massage therapy could significantly increase clinical efficacy[OR=3.95(2.88,5.41),P<0.001],improve lung function[FEV1:SMD=0.90(0.20,1.61),P=0.012]and[PEF:SMD=0.74(0.58,0.91),P<0.001],reduce asthma attacks[SMD=1.25(-1.63,-0.87),P<0.001]and upper respiratory tract infections[SMD=-1.39(-1.63,-1.15),P<0.001];Conclusion:Pediatric massage therapy has a significant effect in the treatment of chronic persistent asthma in children.It can not only improve the pulmonary function,but also effectively prevent the onset of asthma.展开更多
Pediatric diarrhea is a common pediatric disease.Massage has broad application prospects in the treatment of pediatric diarrhea,which is an ideal treatment for pediatric diarrhea.In this paper,the etiology analysis of...Pediatric diarrhea is a common pediatric disease.Massage has broad application prospects in the treatment of pediatric diarrhea,which is an ideal treatment for pediatric diarrhea.In this paper,the etiology analysis of pediatric diarrhea,classification of traditional Chinese medicine(TCM),massage techniques and other aspects were reviewed.In order to provide reference for the clinical application of pediatric massage in the treatment of diarrhea.展开更多
Under the guidance of the theory of spleen and stomach,the author uses the rule of"holding the central,transporting the four sides,regulating emotions,taking spleen and stomach as the center,conditioning the five...Under the guidance of the theory of spleen and stomach,the author uses the rule of"holding the central,transporting the four sides,regulating emotions,taking spleen and stomach as the center,conditioning the five internal organs",applying pediatric massage to treat pediatric spleen and stomach diseases,various acute and chronic diseases and difficult diseases.In the process,the organs are treated,the symptoms are treated,and the curative effect is achieved.展开更多
Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promo...Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promote blood and lymphatic circulation of breast and facilitate the discharge of stagnant milk.This technique is widely used in China to treat breastfeeding problems such as breast engorgement,mastitis,and postpartum hypogalactia.In this article,we introduce the definition and standardization process of breast massage,elaborate the operating procedures of breast massage in detail,and summarize and discuss the current situation of its clinical application,so as to provide a reference for its wide application and in‑depth research.展开更多
Objective:Due to a lack of available effective treatments for atopic eczema (AE),non-pharmaceutical therapy such as Tuina has been frequently sought after as an alternative treatment.We evaluated the benefits and harm...Objective:Due to a lack of available effective treatments for atopic eczema (AE),non-pharmaceutical therapy such as Tuina has been frequently sought after as an alternative treatment.We evaluated the benefits and harms of Tuina for children with AE under 14 years of age.Methods:We searched for randomized controlled trials (RCTs) on Tuina in seven Chinese and English databases from their inception to June 2018.We included children under 14 years of age with AE received Tuina alone or combined with conventional medicine.Two authors independently extracted data and used the Cochrane 'Risk of bias' tool to assess the methodological quality.Effects were presented as relative risk with 95% confidence interval using RevMan 5.3.Data not suitable for statistical pooling were synthesized qualitatively.Results:Nine RCTs involving 1246 children with AE were included.The trials were at unclear or high risk of bias.Tuina manipulation in each trial was different.Compared to usual care,three trials showed greater effects of Tuina alone or combined with usual care for global symptoms and signs improvement,such as itching,and skin lesions.Four trials showed that Tuina had >50% improvement in symptoms and signs.Due to clinical heterogeneity,meta-analysis was not possible.At follow-up of between 4 weeks and 6 months,five trials of Tuina alone or Tuina combined with usual care showed lower rates of relapse compared to usual care alone.Four trials reported no occurrence of severe adverse events.Conclusions:Limited evidence demonstrates that Tuina may improve symptoms and signs of AE and reduce relapse rate in children <14 yrs with AE.Tuina is generally acceptable in these trials.Further well-designed RCTs are warranted to confirm these benefits and to explore safety further.展开更多
基金supported by the National Natural Science Foundation of China (81873392)the Beijing Natural Science Foundation (7192113)
文摘Objective: To investigate the changes in the hypothalamic metabolites of lipopolysaccharide(LPS) febrile young rabbits after the treatment with pediatric tuina.Methods: A total of 30 young rabbits were randomly assigned into three groups: the normal group, the model group, and the tuina group. Both the model group and the tuina group were injected intravenously with LPS. “Six antipyretic manipulations”(pushing Tianmen, pushing Kangong, kneading Taiyang,kneading Erhougaogu, clearing Tianheshui, and pushing Jizhu) were administered 1 h after the LPS injection in the tuina group. The rectal temperatures of the young rabbits were monitored during the experiment to explore the antipyretic effect. Three hours after the injection, the content of interleukin-1β(IL-1β), tumor necrosis factor(TNF)-a, and prostaglandin E;(PGE;) in the serum was detected. In addition, liquid chromatography-mass spectrometry(LC-MS) was used for the hypothalamus metabolomics.Results: Compared with the model group, the rectal temperature of the tuina group was decreased at 2 h and 3 h after the LPS injection(P =.04, P =.03, respectively), and the content of IL-1β, TNF-a, and PGE2was decreased(P =.03, P =.003, and P =.008, respectively). The metabolomics results showed that there were 23 potential biomarkers after the tuina intervention, enriching 27 pathways. Lipid metabolites,especially glycerophospholipids, were a majority of the altered metabolites. The primary metabolic pathways affected by tuina included the arachidonic acid metabolism, the GABAergic synapse, D-glutamine and D-glutamate metabolism, and the glutamatergic synapse.Conclusion: Pediatric tuina reduced the temperature of the febrile rabbits and downregulated the expression of IL-1β, TNF-a, and PGE2, and the antipyretic mechanism may be related to changes in metabolites and metabolic pathways in the hypothalamus.
基金Scientific research project of Shanghai municipal health and family planning commission(20164Y0147)Research project of Shanghai hospital of traditional Chinese medicine(2019LC008)
文摘This paper describes the similarities and differences between three-character scripture school from Shandong, Shanghai pediatric massage and Hunan Liu Kaiyun pediatric massage in the treatment of Recurrent respiratory tract in order to standardize operation, collect references and provide the basis for local infantile massage school.
基金It was supported by Social Science and Technology Development Project of Dongguan with number Dongke[2018]no.95.
文摘Objective:To systematically evaluate the clinical effect of pediatric massage on chronic persistent asthma in children.Methods:We searched relevant literatures through PubMed database,Embase database,Cochrane library,Wanfang database,CNKI and VIP database to screen randomized controlled trials that met the inclusion criteria.According to Cochrane bias risk assessment criteria,the quality of the included literature was evaluated.Finally,Stata 15.1 software was used to analyze the extracted data.Results:A total of 18 studies,1656 participants were included in our Meta analysis.The pooled results showed that pediatric massage therapy could significantly increase clinical efficacy[OR=3.95(2.88,5.41),P<0.001],improve lung function[FEV1:SMD=0.90(0.20,1.61),P=0.012]and[PEF:SMD=0.74(0.58,0.91),P<0.001],reduce asthma attacks[SMD=1.25(-1.63,-0.87),P<0.001]and upper respiratory tract infections[SMD=-1.39(-1.63,-1.15),P<0.001];Conclusion:Pediatric massage therapy has a significant effect in the treatment of chronic persistent asthma in children.It can not only improve the pulmonary function,but also effectively prevent the onset of asthma.
文摘Pediatric diarrhea is a common pediatric disease.Massage has broad application prospects in the treatment of pediatric diarrhea,which is an ideal treatment for pediatric diarrhea.In this paper,the etiology analysis of pediatric diarrhea,classification of traditional Chinese medicine(TCM),massage techniques and other aspects were reviewed.In order to provide reference for the clinical application of pediatric massage in the treatment of diarrhea.
文摘Under the guidance of the theory of spleen and stomach,the author uses the rule of"holding the central,transporting the four sides,regulating emotions,taking spleen and stomach as the center,conditioning the five internal organs",applying pediatric massage to treat pediatric spleen and stomach diseases,various acute and chronic diseases and difficult diseases.In the process,the organs are treated,the symptoms are treated,and the curative effect is achieved.
文摘Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promote blood and lymphatic circulation of breast and facilitate the discharge of stagnant milk.This technique is widely used in China to treat breastfeeding problems such as breast engorgement,mastitis,and postpartum hypogalactia.In this article,we introduce the definition and standardization process of breast massage,elaborate the operating procedures of breast massage in detail,and summarize and discuss the current situation of its clinical application,so as to provide a reference for its wide application and in‑depth research.
文摘Objective:Due to a lack of available effective treatments for atopic eczema (AE),non-pharmaceutical therapy such as Tuina has been frequently sought after as an alternative treatment.We evaluated the benefits and harms of Tuina for children with AE under 14 years of age.Methods:We searched for randomized controlled trials (RCTs) on Tuina in seven Chinese and English databases from their inception to June 2018.We included children under 14 years of age with AE received Tuina alone or combined with conventional medicine.Two authors independently extracted data and used the Cochrane 'Risk of bias' tool to assess the methodological quality.Effects were presented as relative risk with 95% confidence interval using RevMan 5.3.Data not suitable for statistical pooling were synthesized qualitatively.Results:Nine RCTs involving 1246 children with AE were included.The trials were at unclear or high risk of bias.Tuina manipulation in each trial was different.Compared to usual care,three trials showed greater effects of Tuina alone or combined with usual care for global symptoms and signs improvement,such as itching,and skin lesions.Four trials showed that Tuina had >50% improvement in symptoms and signs.Due to clinical heterogeneity,meta-analysis was not possible.At follow-up of between 4 weeks and 6 months,five trials of Tuina alone or Tuina combined with usual care showed lower rates of relapse compared to usual care alone.Four trials reported no occurrence of severe adverse events.Conclusions:Limited evidence demonstrates that Tuina may improve symptoms and signs of AE and reduce relapse rate in children <14 yrs with AE.Tuina is generally acceptable in these trials.Further well-designed RCTs are warranted to confirm these benefits and to explore safety further.
