Background: The PET/CT imaging studies have two doses components the dose from the PET radiopharmaceutical and the other from the low dose CT used for PET images attenuation correction. We have one PET/CT scanner at o...Background: The PET/CT imaging studies have two doses components the dose from the PET radiopharmaceutical and the other from the low dose CT used for PET images attenuation correction. We have one PET/CT scanner at our institution a Philips Time of Flight scanner. Our local patient’s radiation protection rules requires continuous assessment of radiation doses delivered to our patients. Purposes: The objectives of this study are to develop a weight- based facility DRLs for paediatric F-18-FDG PET-CT imaging for oncology in a large tertiary hospital and to determine whether the calculated DRLs compares with internationally published DRLs. Materials & Methods: Radiation dose data and patient demographics of two-hundreds and sixteen paediatric PET-CT oncology patients imaging procedures from one large tertiary hospital were selected and analysed in order to establish a facility paediatric DRLs. Statistical analysis was performed. Results: The PET dose reference levels ranged between [62 - 525] MBq of injected activity for a range of pediatric age groups. The CTDI<sub>vol</sub> values were between 3.5 and 16.5 mGy for all age groups. Comparison with current EANM and SNMMI recommendations of patient’s dose are discussed. Conclusion: Our pediatric PET/CT reference levels are higher than the ones reported internationally with notable variations. .展开更多
背景老年男性恶性肿瘤中,前列腺癌的发病率已位居第2位,其早期筛查有重要临床意义。目的探索前列腺影像报告和数据系统(Prostate Imaging Reporting and Data System,PI-RADS)评分联合^(18)F-PSMA PET/CT评分对前列腺癌的诊断价值。方...背景老年男性恶性肿瘤中,前列腺癌的发病率已位居第2位,其早期筛查有重要临床意义。目的探索前列腺影像报告和数据系统(Prostate Imaging Reporting and Data System,PI-RADS)评分联合^(18)F-PSMA PET/CT评分对前列腺癌的诊断价值。方法回顾性分析2019年1月—2022年11月在解放军总医院行前列腺穿刺活检或手术的124例患者的前列腺磁共振检查(magnetic resonance imaging,MRI)及^(18)F-PSMA PET/CT影像资料,2名影像医师和2名核医学科医师分别对MRI图像和PET/CT图像进行PI-RADS评分和分子成像前列腺特异性膜抗原(molecular imaging prostate specific membrane antigen,miPSMA)评分。以病理结果为金标准,分别以PI-RADS≥3分、miPSMA≥2分以及PI-RADS≥3分联合miPSMA≥2分作为前列腺癌的不同诊断模型,评估各模型的诊断效能。结果124例受试者平均年龄(77.74±10.30)岁,100例被确诊为前列腺癌。以PI-RADS≥3分、miPSMA≥2分以及PI-RADS≥3分联合miPSMA≥2分为标准诊断前列腺癌的敏感度分别为99.0%、96.0%和95.0%;特异度分别为33.3%、83.3%和83.3%;准确度分别为86.3%、93.5%和92.7%;AUC分别为0.662(0.523~0.800)、0.897(0.806~0.987)和0.892(0.801~0.983)。结论前列腺PI-RADS评分≥3分联合miPSMA≥2分有着较高的诊断效能,可作为前列腺癌的精准诊断方案应用于临床。展开更多
目的分析放射性荧光脱氧葡萄糖(18F-FDG)正电子发射断层扫描(PET)/计算机断层扫描(CT)显像在肺癌术前分期诊断及复发转移预测中的应用价值。方法 回顾性分析2022年9月至2023年6月期间80例初诊肺癌患者的临床和影像学数据,所有患者均在术...目的分析放射性荧光脱氧葡萄糖(18F-FDG)正电子发射断层扫描(PET)/计算机断层扫描(CT)显像在肺癌术前分期诊断及复发转移预测中的应用价值。方法 回顾性分析2022年9月至2023年6月期间80例初诊肺癌患者的临床和影像学数据,所有患者均在术前1周内进行了18F-F DG P ET/CT显像检查,并在术后3~6个月内进行了复查,监测复发或转移情况。术前的TNM分期和术后的复发转移情况均以手术病理结果或临床随访结果为金标准进行评估。结果术前分期诊断中,18F-FD(G P ET/CT显像的T分期、N分期和M分期的符合率分别为86.59%、81.93%和100%,一致性检验Kappa值分别为0.834、0.793和1.000。术后的复发转移检测中,18F-FDG PET/CT显像在术后6个月内成功检出了22例(88.00%)的复发转移病例,其诊断灵敏度为88.00%,特异度为100.00%。结论18F-FDG PET/CT显像在肺癌术前分期以及术后复发转移的预测中具有较高的准确性和可靠性,该方法可以为临床提供有效的参考信息,有助于医生制定更准确的治疗方案和更有效的随访策略。展开更多
文摘Background: The PET/CT imaging studies have two doses components the dose from the PET radiopharmaceutical and the other from the low dose CT used for PET images attenuation correction. We have one PET/CT scanner at our institution a Philips Time of Flight scanner. Our local patient’s radiation protection rules requires continuous assessment of radiation doses delivered to our patients. Purposes: The objectives of this study are to develop a weight- based facility DRLs for paediatric F-18-FDG PET-CT imaging for oncology in a large tertiary hospital and to determine whether the calculated DRLs compares with internationally published DRLs. Materials & Methods: Radiation dose data and patient demographics of two-hundreds and sixteen paediatric PET-CT oncology patients imaging procedures from one large tertiary hospital were selected and analysed in order to establish a facility paediatric DRLs. Statistical analysis was performed. Results: The PET dose reference levels ranged between [62 - 525] MBq of injected activity for a range of pediatric age groups. The CTDI<sub>vol</sub> values were between 3.5 and 16.5 mGy for all age groups. Comparison with current EANM and SNMMI recommendations of patient’s dose are discussed. Conclusion: Our pediatric PET/CT reference levels are higher than the ones reported internationally with notable variations. .
文摘背景老年男性恶性肿瘤中,前列腺癌的发病率已位居第2位,其早期筛查有重要临床意义。目的探索前列腺影像报告和数据系统(Prostate Imaging Reporting and Data System,PI-RADS)评分联合^(18)F-PSMA PET/CT评分对前列腺癌的诊断价值。方法回顾性分析2019年1月—2022年11月在解放军总医院行前列腺穿刺活检或手术的124例患者的前列腺磁共振检查(magnetic resonance imaging,MRI)及^(18)F-PSMA PET/CT影像资料,2名影像医师和2名核医学科医师分别对MRI图像和PET/CT图像进行PI-RADS评分和分子成像前列腺特异性膜抗原(molecular imaging prostate specific membrane antigen,miPSMA)评分。以病理结果为金标准,分别以PI-RADS≥3分、miPSMA≥2分以及PI-RADS≥3分联合miPSMA≥2分作为前列腺癌的不同诊断模型,评估各模型的诊断效能。结果124例受试者平均年龄(77.74±10.30)岁,100例被确诊为前列腺癌。以PI-RADS≥3分、miPSMA≥2分以及PI-RADS≥3分联合miPSMA≥2分为标准诊断前列腺癌的敏感度分别为99.0%、96.0%和95.0%;特异度分别为33.3%、83.3%和83.3%;准确度分别为86.3%、93.5%和92.7%;AUC分别为0.662(0.523~0.800)、0.897(0.806~0.987)和0.892(0.801~0.983)。结论前列腺PI-RADS评分≥3分联合miPSMA≥2分有着较高的诊断效能,可作为前列腺癌的精准诊断方案应用于临床。
文摘目的分析放射性荧光脱氧葡萄糖(18F-FDG)正电子发射断层扫描(PET)/计算机断层扫描(CT)显像在肺癌术前分期诊断及复发转移预测中的应用价值。方法 回顾性分析2022年9月至2023年6月期间80例初诊肺癌患者的临床和影像学数据,所有患者均在术前1周内进行了18F-F DG P ET/CT显像检查,并在术后3~6个月内进行了复查,监测复发或转移情况。术前的TNM分期和术后的复发转移情况均以手术病理结果或临床随访结果为金标准进行评估。结果术前分期诊断中,18F-FD(G P ET/CT显像的T分期、N分期和M分期的符合率分别为86.59%、81.93%和100%,一致性检验Kappa值分别为0.834、0.793和1.000。术后的复发转移检测中,18F-FDG PET/CT显像在术后6个月内成功检出了22例(88.00%)的复发转移病例,其诊断灵敏度为88.00%,特异度为100.00%。结论18F-FDG PET/CT显像在肺癌术前分期以及术后复发转移的预测中具有较高的准确性和可靠性,该方法可以为临床提供有效的参考信息,有助于医生制定更准确的治疗方案和更有效的随访策略。
