To compare and evaluate 3 kinds of treatments of pediatric closed femoral shaft fractures.Methods Seventy-nine patients were divided into 3 groups and treated using hip spica casting after skeletal traction,unilateral...To compare and evaluate 3 kinds of treatments of pediatric closed femoral shaft fractures.Methods Seventy-nine patients were divided into 3 groups and treated using hip spica casting after skeletal traction,unilateral multifunctional fixation and plate fixation.The result were evaluated according to clinical function,time to union,complications,radiology examination and the economic cost.Results Both time to union and economic cost of the external fixation group were shorter than that of the skeletal traction group and plate fixation group.Conclusion The unilateral multi-functional external fixation is an ideal solution to pediatric close femoral shaft fractures.7 refs,3 tabs.展开更多
BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the i...BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the increasing resistance to clarithromycin and nitroimidazoles has been associated with treatment failure,and thus,alternative treatment regimens have been proposed.AIM To perform a systematic review of randomized controlled trials on treatment regimens for H.pylori infection in children.METHODS We surveyed relevant articles published in English from 2010 to April 2020 in the PubMed and MEDLINE databases.Keywords included“Helicobacter pylori“/”children or childhood“/”treatment or eradication.”The risk of bias was evaluated according to the Cochrane Handbook of Systematic Reviews for Interventions.RESULTS Among the 1144 records identified through the database,20 articles were selected.Four studies compared the eradication rates of H.pylori infection between standard triple therapies,changing only the main antibiotic used.Seven studies evaluated the effectiveness of standard triple therapy with the addition of probiotics.One study investigated the relationship between the effectiveness in the eradication rates of standard triple therapy and vitamin E levels.Six studies analyzed the eradication rates of sequential therapy.CONCLUSION The findings suggest that although standard triple therapy is the most recommended regimen for children by the current guidelines,other therapeutic schemes have shown promising results and may also be recommended for clinical practice in the future.展开更多
文摘To compare and evaluate 3 kinds of treatments of pediatric closed femoral shaft fractures.Methods Seventy-nine patients were divided into 3 groups and treated using hip spica casting after skeletal traction,unilateral multifunctional fixation and plate fixation.The result were evaluated according to clinical function,time to union,complications,radiology examination and the economic cost.Results Both time to union and economic cost of the external fixation group were shorter than that of the skeletal traction group and plate fixation group.Conclusion The unilateral multi-functional external fixation is an ideal solution to pediatric close femoral shaft fractures.7 refs,3 tabs.
文摘BACKGROUND Helicobacter pylori(H.pylori)infection is predominantly acquired in childhood.When indicated,the most accepted treatment for H.pylori eradication in this age group is first-line triple therapy.However,the increasing resistance to clarithromycin and nitroimidazoles has been associated with treatment failure,and thus,alternative treatment regimens have been proposed.AIM To perform a systematic review of randomized controlled trials on treatment regimens for H.pylori infection in children.METHODS We surveyed relevant articles published in English from 2010 to April 2020 in the PubMed and MEDLINE databases.Keywords included“Helicobacter pylori“/”children or childhood“/”treatment or eradication.”The risk of bias was evaluated according to the Cochrane Handbook of Systematic Reviews for Interventions.RESULTS Among the 1144 records identified through the database,20 articles were selected.Four studies compared the eradication rates of H.pylori infection between standard triple therapies,changing only the main antibiotic used.Seven studies evaluated the effectiveness of standard triple therapy with the addition of probiotics.One study investigated the relationship between the effectiveness in the eradication rates of standard triple therapy and vitamin E levels.Six studies analyzed the eradication rates of sequential therapy.CONCLUSION The findings suggest that although standard triple therapy is the most recommended regimen for children by the current guidelines,other therapeutic schemes have shown promising results and may also be recommended for clinical practice in the future.
