Metabolisms play a vital role in thermoregulation in the human body. The metabolic rate varies with the activity levels and has different behaviors in nature depending on the physical activities of the person. During ...Metabolisms play a vital role in thermoregulation in the human body. The metabolic rate varies with the activity levels and has different behaviors in nature depending on the physical activities of the person. During the activity, metabolic rate increases rapidly at the beginning and then increases slowly to become almost constant after a certain time. So, its behavior is as logistics in nature. The high metabolic rate during activity causes the increase of body core temperature up to 39˚C <a href="#ref1">[1]</a> <a href="#ref2">[2]</a>. The logistic model of metabolic rate is used to re-model Pennes’ bioheat equation for the study of temperature distribution in three layered human dermal parts during carpentering, swimming and marathon. The finite element method is used to obtain the solution of the model equation. The results demonstrate that there is a significant change in tissue temperature due to sweating and ambient temperature variations.展开更多
Based on the biological heat transfer equation of Penne,the internal temperature distribution of the biological tissue was studied,taking into account the evolution of stenosis and hematocrit.The one-dimensional simpl...Based on the biological heat transfer equation of Penne,the internal temperature distribution of the biological tissue was studied,taking into account the evolution of stenosis and hematocrit.The one-dimensional simplifying cylindrical heat equation of the biological living tissues in permanent regime was solved by the FDM(finite difference method)and analytically,to assess the temperature change under the variation of stenosis,hematocrit,K(thermal conductivity),kinematic viscosity,generation of metabolic heat and the heat transfer coefficient.The main results show that the temperature increases as the stenosis and hematocrit increase in size;and the secondary results show that the heat transfer coefficient and the K lower the body temperature while metabolic heat generation increases body temperature.This is in accordance with the literature.展开更多
Reasonable unsteady three-dimensional explicit analytical solutions are derived with different methods for the widely used bio-heat transfer equation–Pennes equation.The condition to decide temperature oscillation is...Reasonable unsteady three-dimensional explicit analytical solutions are derived with different methods for the widely used bio-heat transfer equation–Pennes equation.The condition to decide temperature oscillation is obtained in this paper.In other cases the temperature would vary monotonously along geometric coordinates as time goes by.There have been very few open reports of explicit unsteady multidimensional exact analytical solutions published in literature.Besides its irreplaceable theoretical value,the analytical solution can also serve as standard solution to check numerical calculation,and therefore promote the development of numerical method of computational heat transfer.In addition,some new special methods have been given originally and deserved further attention.展开更多
The revelation of thermal energy exchange mechanism of human body is challenging yet worthwhile,because it can clearly explain the changes in human symptoms and health status.Understanding,the heat transfer of the ski...The revelation of thermal energy exchange mechanism of human body is challenging yet worthwhile,because it can clearly explain the changes in human symptoms and health status.Understanding,the heat transfer of the skin is significant because the skin is the foremost organ for the energy exchange between the human body and the environment.In order to diagnose the physiological conditions of human skin without causing any damage,it is necessary to use a non-invasive measurement technique by means of a conformal flexible sensor.The harmonic method can minimize the thermal-induced injury to the skin due to its low heat generating properties.A novel type of computational theory assessing skin thermal conductivity,blood perfusion rate of capillaries in the dermis,and superficial subcutaneous tissues was formed by combining the multi-medium thermal diffusion model and the bio-thermal model(Pennes equation).The skins of the hand back of six healthy subjects were measured.It was found that the results revealed no consistent changes in thermal conductivity were observed across genders and ages.The measured blood perfusion rates were within the range of human capillary flow.It was found that female subjects had a higher perfusion rate range(0.0058-0.0061 s^(-1))than male subjects(0.0032-0.0049 s^(-1)),which is consistent with invasive medical studies about the gender difference in blood flow rates and stimulated effects in relaxation situations.展开更多
The main purpose of this study is to investigate the thermal behavior of living tissues in the presence of spatial external heat source. An effort has been made to formulate the mathematical model to study the tempera...The main purpose of this study is to investigate the thermal behavior of living tissues in the presence of spatial external heat source. An effort has been made to formulate the mathematical model to study the temperature distribution in in vivo tissues of the human body. The mathematical formulation is governed by bio-heat equation together with appropriate initial, boundary and interface conditions. The solution of the model was carried out using variational finite element method and computational simulations. The model describes the exchange of heat between the internal biological tissues and other surrounding media. The effect of external heat source under different conditions of atmospheric temperature and as a local hyperthermic method provides an impor- tant information to the temperature regulation in biological tissues under normal and malignant conditions. Thermal fluctuations at the targeted regions were obtained with respect to various time-dependent heating sources and scattering coefficients. The results obtained may be helpful for clinical purposes especially in the treatment of cancerous tumors through radiotherapy and other local hyperthermic approaches.展开更多
文摘Metabolisms play a vital role in thermoregulation in the human body. The metabolic rate varies with the activity levels and has different behaviors in nature depending on the physical activities of the person. During the activity, metabolic rate increases rapidly at the beginning and then increases slowly to become almost constant after a certain time. So, its behavior is as logistics in nature. The high metabolic rate during activity causes the increase of body core temperature up to 39˚C <a href="#ref1">[1]</a> <a href="#ref2">[2]</a>. The logistic model of metabolic rate is used to re-model Pennes’ bioheat equation for the study of temperature distribution in three layered human dermal parts during carpentering, swimming and marathon. The finite element method is used to obtain the solution of the model equation. The results demonstrate that there is a significant change in tissue temperature due to sweating and ambient temperature variations.
文摘Based on the biological heat transfer equation of Penne,the internal temperature distribution of the biological tissue was studied,taking into account the evolution of stenosis and hematocrit.The one-dimensional simplifying cylindrical heat equation of the biological living tissues in permanent regime was solved by the FDM(finite difference method)and analytically,to assess the temperature change under the variation of stenosis,hematocrit,K(thermal conductivity),kinematic viscosity,generation of metabolic heat and the heat transfer coefficient.The main results show that the temperature increases as the stenosis and hematocrit increase in size;and the secondary results show that the heat transfer coefficient and the K lower the body temperature while metabolic heat generation increases body temperature.This is in accordance with the literature.
基金supported by the National Natural Science Foundation of China(Grant No.50876106)
文摘Reasonable unsteady three-dimensional explicit analytical solutions are derived with different methods for the widely used bio-heat transfer equation–Pennes equation.The condition to decide temperature oscillation is obtained in this paper.In other cases the temperature would vary monotonously along geometric coordinates as time goes by.There have been very few open reports of explicit unsteady multidimensional exact analytical solutions published in literature.Besides its irreplaceable theoretical value,the analytical solution can also serve as standard solution to check numerical calculation,and therefore promote the development of numerical method of computational heat transfer.In addition,some new special methods have been given originally and deserved further attention.
基金support from the National Natural Science Foundation of China(Nos.52222602,52201261)Beijing Nova Program(No.20220484170)+1 种基金Ningbo 3315 Innovative Teams Program(No.2019A-14-C)Fundamental Research Funds for the Central Universities(Nos.FRF-TP-22-001C1,FRF-EYIT-23-05).
文摘The revelation of thermal energy exchange mechanism of human body is challenging yet worthwhile,because it can clearly explain the changes in human symptoms and health status.Understanding,the heat transfer of the skin is significant because the skin is the foremost organ for the energy exchange between the human body and the environment.In order to diagnose the physiological conditions of human skin without causing any damage,it is necessary to use a non-invasive measurement technique by means of a conformal flexible sensor.The harmonic method can minimize the thermal-induced injury to the skin due to its low heat generating properties.A novel type of computational theory assessing skin thermal conductivity,blood perfusion rate of capillaries in the dermis,and superficial subcutaneous tissues was formed by combining the multi-medium thermal diffusion model and the bio-thermal model(Pennes equation).The skins of the hand back of six healthy subjects were measured.It was found that the results revealed no consistent changes in thermal conductivity were observed across genders and ages.The measured blood perfusion rates were within the range of human capillary flow.It was found that female subjects had a higher perfusion rate range(0.0058-0.0061 s^(-1))than male subjects(0.0032-0.0049 s^(-1)),which is consistent with invasive medical studies about the gender difference in blood flow rates and stimulated effects in relaxation situations.
文摘The main purpose of this study is to investigate the thermal behavior of living tissues in the presence of spatial external heat source. An effort has been made to formulate the mathematical model to study the temperature distribution in in vivo tissues of the human body. The mathematical formulation is governed by bio-heat equation together with appropriate initial, boundary and interface conditions. The solution of the model was carried out using variational finite element method and computational simulations. The model describes the exchange of heat between the internal biological tissues and other surrounding media. The effect of external heat source under different conditions of atmospheric temperature and as a local hyperthermic method provides an impor- tant information to the temperature regulation in biological tissues under normal and malignant conditions. Thermal fluctuations at the targeted regions were obtained with respect to various time-dependent heating sources and scattering coefficients. The results obtained may be helpful for clinical purposes especially in the treatment of cancerous tumors through radiotherapy and other local hyperthermic approaches.