Interventional therapy of coronary heart disease (CHD) includes percutaneous transluminal coronary angioplasty (PTCA), stent implantation etc. Owing to its revascularization without cardiac surgery, it has been the ma...Interventional therapy of coronary heart disease (CHD) includes percutaneous transluminal coronary angioplasty (PTCA), stent implantation etc. Owing to its revascularization without cardiac surgery, it has been the main effective method in treating CHD. But at the same time, there exists the problem of restenosis (RS). After PTCA, RS展开更多
Objective:To investigate the golden-time-awareness of and the necessary actions in response to acute myocardial infarction among the general public.Methods:This study was conducted with the use of a descriptive resear...Objective:To investigate the golden-time-awareness of and the necessary actions in response to acute myocardial infarction among the general public.Methods:This study was conducted with the use of a descriptive research design and convenience sampling.A sample of 800 subjects,using self-structured knowledge questionnaires,was selected for data collection and analysis.The study was conducted at Dr.M.G.R.Educational and Research Institute,India,from February to November 2022.Awareness of myocardial infarction symptoms and intervention timeline(the golden time)was investigated.A multivariate logistic regression analysis was performed to identify the demographic factors affecting the recognition of the golden time of acute myocardial infarction.Results:A total of 800 subjects were included.Among the subjects,367(45.8%)were male,433(54.2%)were female,and 443(55.3%)participants failed to recognize the golden time.Our multivariate logistic regression analysis showed that people with a bachelor’s degree(OR=0.41,95%CI:0.23-0.74,P=0.03)and a high school level diploma(OR=0.55,95%CI:0.31-0.97,P=0.03)are more likely to know about myocardial infarction(golden time)than illiterate people.Additionally,people who are employed(OR=0.59,95%CI:0.41-0.85,P=0.05)are more likely to know about myocardial infarction(golden time)than those who are not.Conclusions:The majority of people in the awareness group realize that taking myocardial infarction patients to the hospital would be the best course of action.The unawareness of the ideal treatment window for myocardial infarction may cause a delay in seeking medical attention,which can lead to an increase in mortality and morbidity.展开更多
目的探讨大剂量阿托伐他汀序贯治疗对急性非ST段抬高型心肌梗死行择期经皮冠状动脉介入治疗（PCI）患者对比剂肾病（CIN）的影响。方法将100例急性非ST段抬高型心肌梗死并择期行PCI患者随机分为大剂量阿托伐他汀序贯治疗组（简称序贯治...目的探讨大剂量阿托伐他汀序贯治疗对急性非ST段抬高型心肌梗死行择期经皮冠状动脉介入治疗（PCI）患者对比剂肾病（CIN）的影响。方法将100例急性非ST段抬高型心肌梗死并择期行PCI患者随机分为大剂量阿托伐他汀序贯治疗组（简称序贯治疗组）和对照组。所有患者入院即刻给予80 mg阿托伐他汀钙,随后40 mg/d,术前均给予水化治疗。序贯治疗组术前6 h内追加40 mg阿托伐他汀钙,对照组术前未追加阿托伐他汀钙。所有患者分别于PCI术前、术后24 h、48 h测定并比较血清肌酐（Scr）、内生肌酐清除率（Ccr）和CIN发生率。结果两组患者术前、术后24 h、48 h Scr和Ccr相比差异均无统计学意义;与术前相比,序贯治疗组术后24 h、48 h Scr和Ccr均无明显变化,对照组术后24 h Scr和Ccr无明显变化,术后48 h Scr明显上升,Ccr明显下降（P〈0.05）。与术后24 h比较,两组术后48 h Scr明显上升,Ccr明显下降（P=0.00）。所有CIN患者术后7～10天Scr均降至正常范围内;两组患者CIN发生率相比差异无统计学意义（16%比15%,P=0.585）。结论对于术前已使用阿托伐他汀钙40 mg/d调脂方案患者,围手术期再次予阿托伐他汀钙40 mg治疗并不能降低CIN发生率。展开更多
文摘Interventional therapy of coronary heart disease (CHD) includes percutaneous transluminal coronary angioplasty (PTCA), stent implantation etc. Owing to its revascularization without cardiac surgery, it has been the main effective method in treating CHD. But at the same time, there exists the problem of restenosis (RS). After PTCA, RS
文摘Objective:To investigate the golden-time-awareness of and the necessary actions in response to acute myocardial infarction among the general public.Methods:This study was conducted with the use of a descriptive research design and convenience sampling.A sample of 800 subjects,using self-structured knowledge questionnaires,was selected for data collection and analysis.The study was conducted at Dr.M.G.R.Educational and Research Institute,India,from February to November 2022.Awareness of myocardial infarction symptoms and intervention timeline(the golden time)was investigated.A multivariate logistic regression analysis was performed to identify the demographic factors affecting the recognition of the golden time of acute myocardial infarction.Results:A total of 800 subjects were included.Among the subjects,367(45.8%)were male,433(54.2%)were female,and 443(55.3%)participants failed to recognize the golden time.Our multivariate logistic regression analysis showed that people with a bachelor’s degree(OR=0.41,95%CI:0.23-0.74,P=0.03)and a high school level diploma(OR=0.55,95%CI:0.31-0.97,P=0.03)are more likely to know about myocardial infarction(golden time)than illiterate people.Additionally,people who are employed(OR=0.59,95%CI:0.41-0.85,P=0.05)are more likely to know about myocardial infarction(golden time)than those who are not.Conclusions:The majority of people in the awareness group realize that taking myocardial infarction patients to the hospital would be the best course of action.The unawareness of the ideal treatment window for myocardial infarction may cause a delay in seeking medical attention,which can lead to an increase in mortality and morbidity.
文摘目的探讨大剂量阿托伐他汀序贯治疗对急性非ST段抬高型心肌梗死行择期经皮冠状动脉介入治疗（PCI）患者对比剂肾病（CIN）的影响。方法将100例急性非ST段抬高型心肌梗死并择期行PCI患者随机分为大剂量阿托伐他汀序贯治疗组（简称序贯治疗组）和对照组。所有患者入院即刻给予80 mg阿托伐他汀钙,随后40 mg/d,术前均给予水化治疗。序贯治疗组术前6 h内追加40 mg阿托伐他汀钙,对照组术前未追加阿托伐他汀钙。所有患者分别于PCI术前、术后24 h、48 h测定并比较血清肌酐（Scr）、内生肌酐清除率（Ccr）和CIN发生率。结果两组患者术前、术后24 h、48 h Scr和Ccr相比差异均无统计学意义;与术前相比,序贯治疗组术后24 h、48 h Scr和Ccr均无明显变化,对照组术后24 h Scr和Ccr无明显变化,术后48 h Scr明显上升,Ccr明显下降（P〈0.05）。与术后24 h比较,两组术后48 h Scr明显上升,Ccr明显下降（P=0.00）。所有CIN患者术后7～10天Scr均降至正常范围内;两组患者CIN发生率相比差异无统计学意义（16%比15%,P=0.585）。结论对于术前已使用阿托伐他汀钙40 mg/d调脂方案患者,围手术期再次予阿托伐他汀钙40 mg治疗并不能降低CIN发生率。
