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Impact of perioperative blood transfusion on oncological outcomes in ampullary carcinoma patients underwent pancreaticoduodenectomy
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作者 He Fei Xiao-Jie Zhang +4 位作者 Chong-Yuan Sun Zheng Li Ze-Feng Li Chun-Guang Guo Dong-Bing Zhao 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第7期1363-1374,共12页
BACKGROUND The effect of perioperative blood transfusion(PBT)on the prognosis of ampullary carcinoma(AC)is still debated.AIM To explore the impact of PBT on short-term safety and long-term survival in AC patients who ... BACKGROUND The effect of perioperative blood transfusion(PBT)on the prognosis of ampullary carcinoma(AC)is still debated.AIM To explore the impact of PBT on short-term safety and long-term survival in AC patients who underwent pancreaticoduodenectomy.METHODS A total of 257 patients with AC who underwent pancreaticoduodenectomy between 1998 and 2020 in the Cancer Hospital,Chinese Academy of Medical Sciences,were retrospectively analyzed.We used Cox proportional hazard regression to identify prognostic factors of overall survival(OS)and recurrencefree survival(RFS)and the Kaplan-Meier method to analyze survival information.RESULTS A total of 144(56%)of 257 patients received PBT.The PBT group and nonperioperative blood transfusion group showed no significant differences in demographics.Patients who received transfusion had a comparable incidence of postoperative complications with patients who did not.Univariable and multivariable Cox proportional hazard regression analyses indicated that transfusion was not an independent predictor of OS or RFS.We performed Kaplan-Meier analysis according to subgroups of T stage,and subgroup analysis indicated that PBT might be associated with worse OS(P<0.05)but not RFS in AC of stage T1.CONCLUSION We found that PBT might be associated with decreased OS in early AC,but more validation is needed.The reasonable use of transfusion might be helpful to improve OS. 展开更多
关键词 Ampullary carcinoma perioperative blood transfusion PANCREATICODUODENECTOMY PROGNOSIS
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Study of changes and relationships of cytokines in esophageal cancer patients exposed to perioperative allogeneic transfusion
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《中国输血杂志》 CAS CSCD 2001年第S1期335-,共1页
关键词 Study of changes and relationships of cytokines in esophageal cancer patients exposed to perioperative allogeneic transfusion
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