Patients with a diagnosis of polycystic ovary syndrome （PCOS） are on the rise. About 4%-12% of women are currently estimated to have this condition. It is hypothesized that PCOS appears in women who have long-standi...Patients with a diagnosis of polycystic ovary syndrome （PCOS） are on the rise. About 4%-12% of women are currently estimated to have this condition. It is hypothesized that PCOS appears in women who have long-standing insulin resistance （1R）, which leads to high androgen and testosterone levels; this ultimately disrupts their menstrual cycles. Some researchers attribute IR to genetic factors, although there have been only minute changes in the human genome in the past 20 000 years. However, even with a stable gene pool, genes can be turned on and offby the environment, food and air quality and toxin exposure.展开更多
One-dimensional liquid chromatography(1D-LC)is routinely applied to the analysis of all kinds of samples in different fields.With the introduction of UHPLC instruments and sub-2micron particle columns,the separation e...One-dimensional liquid chromatography(1D-LC)is routinely applied to the analysis of all kinds of samples in different fields.With the introduction of UHPLC instruments and sub-2micron particle columns,the separation efficiency was greatly improved.To resolve all components of complex samples,however,1D-LC does not provide enough resolving power,or peak capacity.In addition,to separate compounds co-eluting in 1D-LC,increasing the separation efficiency by increasing展开更多
文摘Patients with a diagnosis of polycystic ovary syndrome （PCOS） are on the rise. About 4%-12% of women are currently estimated to have this condition. It is hypothesized that PCOS appears in women who have long-standing insulin resistance （1R）, which leads to high androgen and testosterone levels; this ultimately disrupts their menstrual cycles. Some researchers attribute IR to genetic factors, although there have been only minute changes in the human genome in the past 20 000 years. However, even with a stable gene pool, genes can be turned on and offby the environment, food and air quality and toxin exposure.
文摘One-dimensional liquid chromatography(1D-LC)is routinely applied to the analysis of all kinds of samples in different fields.With the introduction of UHPLC instruments and sub-2micron particle columns,the separation efficiency was greatly improved.To resolve all components of complex samples,however,1D-LC does not provide enough resolving power,or peak capacity.In addition,to separate compounds co-eluting in 1D-LC,increasing the separation efficiency by increasing
