Plant diterpenoids are widely distributed and abundant natural products with diverse structures and functions in nature,which have been commonly used in pharmaceutical,agricultural and industrial production.In recent ...Plant diterpenoids are widely distributed and abundant natural products with diverse structures and functions in nature,which have been commonly used in pharmaceutical,agricultural and industrial production.In recent years,plant diterpenoids have attracted increasing attention,including their biosynthetic pathways,transcriptional regulatory networks,and biological functions.Herein,the biosynthetic pathways of diterpenoids are summarized in a modular fashion.Further,the regulatory network between diterpene biosynthesis and environmental factors is reviewed.Insights into diterpene metabolism may drive elucidation of complex active diterpene pathways and serve as a knowledge repository for metabolic engineering and cell factory construction.展开更多
基金supported by the National Natural Science Foundation of China(Nos.82225047,32000231,31970316 and 32170274)Shanghai Sail Program(No.19YF1459300).
文摘Plant diterpenoids are widely distributed and abundant natural products with diverse structures and functions in nature,which have been commonly used in pharmaceutical,agricultural and industrial production.In recent years,plant diterpenoids have attracted increasing attention,including their biosynthetic pathways,transcriptional regulatory networks,and biological functions.Herein,the biosynthetic pathways of diterpenoids are summarized in a modular fashion.Further,the regulatory network between diterpene biosynthesis and environmental factors is reviewed.Insights into diterpene metabolism may drive elucidation of complex active diterpene pathways and serve as a knowledge repository for metabolic engineering and cell factory construction.
