In Japanese pharmacies, Drug Profile Books (DPBs), which are a type of Personal Health Record (PHR), are incorporated in order to prevent duplicate medication and drug interactions in outpatients (patients) through th...In Japanese pharmacies, Drug Profile Books (DPBs), which are a type of Personal Health Record (PHR), are incorporated in order to prevent duplicate medication and drug interactions in outpatients (patients) through the uniform management of drug administration information. In this study, we tried to clarify the effect on patient safety of brief interventions via DPBs by pharmacists. The study design was a randomized controlled trial on pharmacies as clusters. 65 pharmacies agreed to participate in the study (intervention group (IG): 33;control group (CG): 32). The primary outcomes were: rate of inquiry occurrence, rate of prescription change, and rates of duplicate medications & drug interactions. 56 pharmacies (IG: 29;CG: 27) completed the study. There was a higher tendency for prescription changes in the IG compared to the CG (IG: 0.03%;CG: 0.02%;P = 0.08). In addition, the rate of duplicate medications & drug interactions accounting for the inquiries was significantly higher in the IG than in the CG (IG: 89.2%;CG: 71.9%;P = 0.01). This implied that brief interventions by pharmacists using DPBs had an effect in raising patient safety.展开更多
目的 探讨欧洲药学监护网络(pharmaceutical care network of Europe,PCNE)分类系统用于解决泌尿外科药物相关问题(drugrelated problems,DRPs)及进行药学监护过程中的作用。方法 采用PCNE(9.1版)分类系统对某院3个典型泌尿外科患者发...目的 探讨欧洲药学监护网络(pharmaceutical care network of Europe,PCNE)分类系统用于解决泌尿外科药物相关问题(drugrelated problems,DRPs)及进行药学监护过程中的作用。方法 采用PCNE(9.1版)分类系统对某院3个典型泌尿外科患者发生的药物相关性问题(DRPs)进行药学干预分析。结果 3个病例中发生DRPs 1~3个,药物选择、剂量选择和治疗疗程是导致DRPs发生的主要原因。结论 药师借助PCNE分类系统可及时、准确识别DRPs,包括已发生的及潜在的DRPs,实现精准、完整的药学监护模式。展开更多
目的分析药学干预对2型糖尿病患者用药依从性与药品不良反应的影响。方法100例2型糖尿病患者,利用随机数字表法分为常规组和研究组,每组50例。常规组患者采用常规用药干预,研究组患者采用药学干预。比较两组患者的用药依从性、不良反应...目的分析药学干预对2型糖尿病患者用药依从性与药品不良反应的影响。方法100例2型糖尿病患者,利用随机数字表法分为常规组和研究组,每组50例。常规组患者采用常规用药干预,研究组患者采用药学干预。比较两组患者的用药依从性、不良反应发生情况、血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 h PG)以及糖化血红蛋白(HbA1c)]水平、血脂指标[甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)]水平以及生活质量。结果研究组患者用药总依从率为96.00%,高于常规组的82.00%(P<0.05)。研究组患者不良反应发生率为6.00%,低于常规组的22.00%(P<0.05)。干预后,研究组患者FPG、2 h PG、HbA1c水平分别为(5.15±1.11)mmol/L、(9.65±1.22)mmol/L、(6.07±1.15)%,均低于常规组的(6.52±1.12)mmol/L、(11.43±1.26)mmol/L、(7.43±1.14)%(P<0.05)。干预后,研究组患者TC(4.52±0.34)mmol/L、TG(2.03±0.12)mmol/L、LDL-C(2.31±0.44)mmol/L均低于常规组的(5.21±0.31)、(2.35±0.12)、(2.82±0.51)mmol/L,HDL-C(1.42±0.14)mmol/L高于常规组的(1.22±0.14)mmol/L(P<0.05)。干预后,研究组患者情感职能、生理功能、社会功能、活力评分分别为(77.56±1.52)、(74.34±1.22)、(77.32±1.25)、(72.64±1.25)分,均高于常规组的(63.76±1.44)、(64.25±1.13)、(63.23±1.21)、(61.31±1.24)分(P<0.05)。结论对2型糖尿病患者采用药学干预,有助于改善患者的生活质量、血脂水平与血糖水平,对降低患者不良反应发生率以及提升患者用药依从性具有积极影响。展开更多
文摘In Japanese pharmacies, Drug Profile Books (DPBs), which are a type of Personal Health Record (PHR), are incorporated in order to prevent duplicate medication and drug interactions in outpatients (patients) through the uniform management of drug administration information. In this study, we tried to clarify the effect on patient safety of brief interventions via DPBs by pharmacists. The study design was a randomized controlled trial on pharmacies as clusters. 65 pharmacies agreed to participate in the study (intervention group (IG): 33;control group (CG): 32). The primary outcomes were: rate of inquiry occurrence, rate of prescription change, and rates of duplicate medications & drug interactions. 56 pharmacies (IG: 29;CG: 27) completed the study. There was a higher tendency for prescription changes in the IG compared to the CG (IG: 0.03%;CG: 0.02%;P = 0.08). In addition, the rate of duplicate medications & drug interactions accounting for the inquiries was significantly higher in the IG than in the CG (IG: 89.2%;CG: 71.9%;P = 0.01). This implied that brief interventions by pharmacists using DPBs had an effect in raising patient safety.
文摘目的分析药学干预对2型糖尿病患者用药依从性与药品不良反应的影响。方法100例2型糖尿病患者,利用随机数字表法分为常规组和研究组,每组50例。常规组患者采用常规用药干预,研究组患者采用药学干预。比较两组患者的用药依从性、不良反应发生情况、血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 h PG)以及糖化血红蛋白(HbA1c)]水平、血脂指标[甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)]水平以及生活质量。结果研究组患者用药总依从率为96.00%,高于常规组的82.00%(P<0.05)。研究组患者不良反应发生率为6.00%,低于常规组的22.00%(P<0.05)。干预后,研究组患者FPG、2 h PG、HbA1c水平分别为(5.15±1.11)mmol/L、(9.65±1.22)mmol/L、(6.07±1.15)%,均低于常规组的(6.52±1.12)mmol/L、(11.43±1.26)mmol/L、(7.43±1.14)%(P<0.05)。干预后,研究组患者TC(4.52±0.34)mmol/L、TG(2.03±0.12)mmol/L、LDL-C(2.31±0.44)mmol/L均低于常规组的(5.21±0.31)、(2.35±0.12)、(2.82±0.51)mmol/L,HDL-C(1.42±0.14)mmol/L高于常规组的(1.22±0.14)mmol/L(P<0.05)。干预后,研究组患者情感职能、生理功能、社会功能、活力评分分别为(77.56±1.52)、(74.34±1.22)、(77.32±1.25)、(72.64±1.25)分,均高于常规组的(63.76±1.44)、(64.25±1.13)、(63.23±1.21)、(61.31±1.24)分(P<0.05)。结论对2型糖尿病患者采用药学干预,有助于改善患者的生活质量、血脂水平与血糖水平,对降低患者不良反应发生率以及提升患者用药依从性具有积极影响。
