Recently,a Rydberg atom-based mixer was developed to measure the phase of a radio frequency(RF)field.The phase of the signal RF(SIG RF)field is down-converted directly to the phase of a beat signal created by the pres...Recently,a Rydberg atom-based mixer was developed to measure the phase of a radio frequency(RF)field.The phase of the signal RF(SIG RF)field is down-converted directly to the phase of a beat signal created by the presence of a local RF(LO RF)field.In this study,we propose that the Rydberg atom-based mixer can be converted to an all-optical phase detector by amplitude modulation(AM)of the LO RF field;that is,the phase of the SIG RF field is related to both the amplitude and phase of the beat signal.When the AM frequency of the LO RF field is the same as the frequency of the beat signal,the beat signal will further interfere with the AM of the LO RF field inside the atom,and then the amplitude of the beat signal is related to the phase of the SIG RF field.The amplitude of the beat signal and the phase of the SIG RF field show a linear relationship within the range of 0 toπ/2 when the phase of the AM is set with a differenceπ/4 from the phase of the LO RF field.The minimum phase resolution can be as small as 0.6°by optimizing the experimental conditions according to a simple theoretical model.This study will expand and contribute to the development of RF measurement devices based on Rydberg atoms.展开更多
A real time system used to detect phase difference between two sinusoidal signals is proposed in this paper. The system is designed to process the phase signal of the far-infrared (FIR) hydrogen cyanide (HCN) inte...A real time system used to detect phase difference between two sinusoidal signals is proposed in this paper. The system is designed to process the phase signal of the far-infrared (FIR) hydrogen cyanide (HCN) interferometer on J-TEXT. It is based on zero-crossing detection and makes use of the digital circuit. Compared with a traditional zero-crossing phase detector, it doesn't need to sacrifice the time resolution to expand the phase range. The phase difference is divided into two parts, the integer part and the fraction part. In each detecting cycle, they are detected separately. It outputs digital signals that are more stable for transmission. A prototype was built on J-TEXT using discrete components. A practical method is proposed to deal with the counting error caused by the deviation of electronic components in manufacture. Reasonable results were obtained on the prototype. The phase resolution reaches 2π/64 in test, and can still be improved by raising the clock frequency.展开更多
In order to improve the performance of the existing phase frequency detectors (PFDs), a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparison...In order to improve the performance of the existing phase frequency detectors (PFDs), a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparisons are made. A new robust CMOS phase frequency detector for a high speed and low jitter charge pump phrase-locked loop (PLL) is designed. The proposed PFD consists of two rising-edge triggered dynamic D flip-flops, two positive-edge detectors and delaying units and two OR gates. It adopts two reset mechanisms to avoid the LIP and DN signals to be logic-1 simultaneously. Thus, any current mismatch of the charge pump circuit will not worsen the performance of the PLL. Furthermore, it has hardly any dead-zone phenomenon in phase characteristic. Simulations with ADS are performed based on a TSMC 0. 18-μm CMOS process with a 1.8-V supply voltage. According to the theoretical analyses and simulation results, the proposed PFD shows a satisfactory performance with a high operation frequency (≈ 1 GHz), a wide phase-detection range [ ± 2π], a near zero dead-zone ( 〈 0. 1 ps), high reliability, low phase jitter, low power consumption ( ≈100 μW) and small circuit complexity.展开更多
In order to improve the precision of the laser–radio-frequency(RF) synchronization system from sub-picosecond to femtosecond(fs), a synchronization system between a picosecond laser and a 1.3 GHz RF generator has...In order to improve the precision of the laser–radio-frequency(RF) synchronization system from sub-picosecond to femtosecond(fs), a synchronization system between a picosecond laser and a 1.3 GHz RF generator has been developed based on a fiber-loop optical-microwave phase detector(FLOM-PD). Synchronization with fs-level(3.8 fs) rms jitter, integrated from 10 Hz to 1 MHz, is achieved for the first time, to the best of our knowledge, in this kind of configuration. This system will be used for the superconducting RF accelerator at Peking University.展开更多
The design and realization of a new generation of infra-red electronic distance measurement (IR EDM) system are presented.A DSP(Digital Signal Process) phase detector based on high speed analog-to-digital converter an...The design and realization of a new generation of infra-red electronic distance measurement (IR EDM) system are presented.A DSP(Digital Signal Process) phase detector based on high speed analog-to-digital converter and DSP technique has been designed,in order to improve the precision and reliability of IR EDM system.As a result,the EDM system developed with a DSP phase detector has a precision of 3 mm in the measuring range of 2 km.展开更多
Based on 0.13μm complementary metal-oxide-semiconductor(CMOS) technology,a phase and frequency detector(PFD) is designed with a low supply voltage of 0.5V for frequency synthesizers used in wireless sensor netwo...Based on 0.13μm complementary metal-oxide-semiconductor(CMOS) technology,a phase and frequency detector(PFD) is designed with a low supply voltage of 0.5V for frequency synthesizers used in wireless sensor networks(WSNs).The PFD can compare the frequency and phase differences of input signals and deliver a signal voltage proportional to the difference.Low threshold transistors are used in the circuits since a power supply of 0.5V is adopted.A pulse latched structure is also used in the circuits in order to increase both the detection range of phase errors and the maximum operation frequency.In experiments,a phase error with a range from-358° to 358° is measured when the input signal frequency is 2MHz.The PFD has a faster acquisition speed compared with conventional digital PFDs.When the input signals are at a frequency of 2MHz with zero phase error,the circuits have a power consumption of 1.8[KG*8]μW,and the maximum operation frequency is 1.25GHz.展开更多
In this paper, we proposed the scheme for a passive round-robin differential-phase-shift quantum key distribution(RRDPS-QKD) set-up based on the principle of Hong–Ou–Mandel interference. Our scheme requires two le...In this paper, we proposed the scheme for a passive round-robin differential-phase-shift quantum key distribution(RRDPS-QKD) set-up based on the principle of Hong–Ou–Mandel interference. Our scheme requires two legitimate parties to prepare their signal state with two different non-orthogonal bases instead of single in original protocol. Incorporating this characteristic, we establish the level of security of our protocol under the intercept-resend attack and demonstrate its detector-flaw-immune feature. Furthermore, we show that our scheme not only inherits the merit of better tolerance of bit errors and finite-sized-key effects but can be implemented using hardware similar to the measurement device independent QKD(MDI-QKD). This ensures good compatibility with the current commonly used quantum system.展开更多
An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop (DLL) with a proposed quadrature phase detector to greatly reduce the phase error....An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop (DLL) with a proposed quadrature phase detector to greatly reduce the phase error. The receiver is fabricated in a 0.18μm CMOS process. Measurements show that the IQ phase error can be calibrated within 1°,which satisfies the system requirement.展开更多
The paper presents a kind of transmission system which employs M-ary Position Phase Shift Keying(MPPSK) to send data and Phase Locked Loop(PLL) based techniques for data retrieve.With a single PLL, MPPSK demodulation ...The paper presents a kind of transmission system which employs M-ary Position Phase Shift Keying(MPPSK) to send data and Phase Locked Loop(PLL) based techniques for data retrieve.With a single PLL, MPPSK demodulation is achieved, as well as carrier recovery and symbol synchronization.Firstly, MPPSK modulation method is briefly introduced.2PPSK's PSD expression is given with its optimization result.Orthogonal Phase Detector(PD) and static threshold are used for the purpose of wider phase range and simplicity in demodulation.The data rate is alterable, which is 4.65 kbps for 2PPSK and 9.3 kbps for 4PPSK in the paper.Then some indicative comparisons in Signal to Noise Ratio Symbol Error Rate(SNR-SER) are made among 2PPSK, 3PPSK and 4PPSK, of which 4PPSK has proved to be optimal in ten slots each symbol conditions.And finally, it is demonstrated by system simulations that lower than 10-4 Symbol Error Rate(SER) performance can be obtained at 13 dB symbol SNR.展开更多
The design of phase control system in Shanghai Synchrotron Radiation Facility (SSRF) linac is presented in this paper. And digital phase detecting algorithm, the key for phase control system, is fully described. The t...The design of phase control system in Shanghai Synchrotron Radiation Facility (SSRF) linac is presented in this paper. And digital phase detecting algorithm, the key for phase control system, is fully described. The testing results for phase control system in 100MeV linac are discussed in detail.展开更多
Cetuximab (CTX) is a potent chimeric mouse/human monoclonal antibody (mAb) approved worldwide for treatment of metastatic colorectal cancer. Among the various biological and physical analyses per- formed for full ...Cetuximab (CTX) is a potent chimeric mouse/human monoclonal antibody (mAb) approved worldwide for treatment of metastatic colorectal cancer. Among the various biological and physical analyses per- formed for full study on this biopharmaceutic, the determination of the concentration preparations throughout manufacturing and subsequent handling in hospital is particularly relevant. In the present work, the study and validation of a method for quantifying intact CTX by reverse-phase high-perfor- mance liquid chromatography with diode array detection ((RP)HPLC/DAD) is presented. With that end, we checked the performance of a chromatographic method for quantifying CTX and conducted a study to validate the method as stability-indicating in accordance with the International Conference on Harmo- nization guidelines (ICH) for biotechnological drugs; therefore, we evaluated linearity, accuracy, preci- sion, detection and quantification limits, robustness and system suitability. The specificity of the method and the robustness of the mAb formulation against external stress factors were estimated by compre- hensive chromatographic analysis by subjecting CTX to several informative stress conditions. As de- monstrated, the method is rapid, accurate, and reproducible for CTX quantification. It was also suc- cessfully used to quantify CTX in a long-term stability study performed under hospital conditions.展开更多
A multisampling technique was introduced to the phase error detector of Conventional Digital Tanlocked Loop(C DTL). In this new technique a number of samples ( M ) were taken at nonuniform intervals within one peri...A multisampling technique was introduced to the phase error detector of Conventional Digital Tanlocked Loop(C DTL). In this new technique a number of samples ( M ) were taken at nonuniform intervals within one period of the input signal. The novel system is called Multisampling Digital Tanlocked loop(MS DTL). The simulated model on the computer shows that for M =4, the system has a faster locking speed and wider locking in range compared with C DTL.展开更多
A method termed hollow fiber liquid phase microextraction (HF-LPME) was utilized to extract three chlo- rophenols, 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP) and 2,4,6- trichlorophenol (2,4,6-TCP), separately...A method termed hollow fiber liquid phase microextraction (HF-LPME) was utilized to extract three chlo- rophenols, 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP) and 2,4,6- trichlorophenol (2,4,6-TCP), separately from water. The extracted chlorophenols were then separated, identified, and quantified by UV-Vis spectrophotometry with photodiode array detection (UV-Vis/DAD). In the study, experimental con-ditions such as organic phase identity, acceptor phase volume, sample agitation, extraction time, acceptor phase NaOH concentration, donor phase HCl concentration, salt addition, and UV absorption wavelength were optimized. The statistical parameters of the proposed method were investigated under the selected con-ditions. The analytical characteristics of the method such as detection limit, accuracy, precision, relative standard deviation (R.S.D.) and relative standard error (R.S.E.) was calculated. The results showed that the proposed method is simple, rapid, accurate and precise for the analysis of ternary mixtures.展开更多
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFA0304900 and 2017YFA0402300)the Beijing Natural Science Foundation(Grant No.1212014)+3 种基金the National Natural Science Foundation of China(Grant Nos.11604334,11604177,and U2031125)the Key Research Program of the Chinese Academy of Sciences(Grant No.XDPB08-3)the Open Research Fund Program of the State Key Laboratory of Low-Dimensional Quantum Physics(Grant No.KF201807)the Fundamental Research Funds for the Central Universities,and Youth Innovation Promotion Association CAS.
文摘Recently,a Rydberg atom-based mixer was developed to measure the phase of a radio frequency(RF)field.The phase of the signal RF(SIG RF)field is down-converted directly to the phase of a beat signal created by the presence of a local RF(LO RF)field.In this study,we propose that the Rydberg atom-based mixer can be converted to an all-optical phase detector by amplitude modulation(AM)of the LO RF field;that is,the phase of the SIG RF field is related to both the amplitude and phase of the beat signal.When the AM frequency of the LO RF field is the same as the frequency of the beat signal,the beat signal will further interfere with the AM of the LO RF field inside the atom,and then the amplitude of the beat signal is related to the phase of the SIG RF field.The amplitude of the beat signal and the phase of the SIG RF field show a linear relationship within the range of 0 toπ/2 when the phase of the AM is set with a differenceπ/4 from the phase of the LO RF field.The minimum phase resolution can be as small as 0.6°by optimizing the experimental conditions according to a simple theoretical model.This study will expand and contribute to the development of RF measurement devices based on Rydberg atoms.
基金supported by National Natural Science Foundation of China(Nos.11005043 and 11105056)
文摘A real time system used to detect phase difference between two sinusoidal signals is proposed in this paper. The system is designed to process the phase signal of the far-infrared (FIR) hydrogen cyanide (HCN) interferometer on J-TEXT. It is based on zero-crossing detection and makes use of the digital circuit. Compared with a traditional zero-crossing phase detector, it doesn't need to sacrifice the time resolution to expand the phase range. The phase difference is divided into two parts, the integer part and the fraction part. In each detecting cycle, they are detected separately. It outputs digital signals that are more stable for transmission. A prototype was built on J-TEXT using discrete components. A practical method is proposed to deal with the counting error caused by the deviation of electronic components in manufacture. Reasonable results were obtained on the prototype. The phase resolution reaches 2π/64 in test, and can still be improved by raising the clock frequency.
文摘In order to improve the performance of the existing phase frequency detectors (PFDs), a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparisons are made. A new robust CMOS phase frequency detector for a high speed and low jitter charge pump phrase-locked loop (PLL) is designed. The proposed PFD consists of two rising-edge triggered dynamic D flip-flops, two positive-edge detectors and delaying units and two OR gates. It adopts two reset mechanisms to avoid the LIP and DN signals to be logic-1 simultaneously. Thus, any current mismatch of the charge pump circuit will not worsen the performance of the PLL. Furthermore, it has hardly any dead-zone phenomenon in phase characteristic. Simulations with ADS are performed based on a TSMC 0. 18-μm CMOS process with a 1.8-V supply voltage. According to the theoretical analyses and simulation results, the proposed PFD shows a satisfactory performance with a high operation frequency (≈ 1 GHz), a wide phase-detection range [ ± 2π], a near zero dead-zone ( 〈 0. 1 ps), high reliability, low phase jitter, low power consumption ( ≈100 μW) and small circuit complexity.
基金supported by National Key Research and Development Program of China under Grant No.2016YFA0401904
文摘In order to improve the precision of the laser–radio-frequency(RF) synchronization system from sub-picosecond to femtosecond(fs), a synchronization system between a picosecond laser and a 1.3 GHz RF generator has been developed based on a fiber-loop optical-microwave phase detector(FLOM-PD). Synchronization with fs-level(3.8 fs) rms jitter, integrated from 10 Hz to 1 MHz, is achieved for the first time, to the best of our knowledge, in this kind of configuration. This system will be used for the superconducting RF accelerator at Peking University.
文摘The design and realization of a new generation of infra-red electronic distance measurement (IR EDM) system are presented.A DSP(Digital Signal Process) phase detector based on high speed analog-to-digital converter and DSP technique has been designed,in order to improve the precision and reliability of IR EDM system.As a result,the EDM system developed with a DSP phase detector has a precision of 3 mm in the measuring range of 2 km.
基金The National High Technology Research and Development Program of China (863 Program) (No. 2007AA01Z2A7)Program for Special Talents in Six Fields of Jiangsu Province
文摘Based on 0.13μm complementary metal-oxide-semiconductor(CMOS) technology,a phase and frequency detector(PFD) is designed with a low supply voltage of 0.5V for frequency synthesizers used in wireless sensor networks(WSNs).The PFD can compare the frequency and phase differences of input signals and deliver a signal voltage proportional to the difference.Low threshold transistors are used in the circuits since a power supply of 0.5V is adopted.A pulse latched structure is also used in the circuits in order to increase both the detection range of phase errors and the maximum operation frequency.In experiments,a phase error with a range from-358° to 358° is measured when the input signal frequency is 2MHz.The PFD has a faster acquisition speed compared with conventional digital PFDs.When the input signals are at a frequency of 2MHz with zero phase error,the circuits have a power consumption of 1.8[KG*8]μW,and the maximum operation frequency is 1.25GHz.
基金Project supported by the Fund from the State Key Laboratory of Information Photonics and Optical Communications(Beijing University of Posts and Telecommunications)(Grant No.IPOC2017ZT0)
文摘In this paper, we proposed the scheme for a passive round-robin differential-phase-shift quantum key distribution(RRDPS-QKD) set-up based on the principle of Hong–Ou–Mandel interference. Our scheme requires two legitimate parties to prepare their signal state with two different non-orthogonal bases instead of single in original protocol. Incorporating this characteristic, we establish the level of security of our protocol under the intercept-resend attack and demonstrate its detector-flaw-immune feature. Furthermore, we show that our scheme not only inherits the merit of better tolerance of bit errors and finite-sized-key effects but can be implemented using hardware similar to the measurement device independent QKD(MDI-QKD). This ensures good compatibility with the current commonly used quantum system.
文摘An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop (DLL) with a proposed quadrature phase detector to greatly reduce the phase error. The receiver is fabricated in a 0.18μm CMOS process. Measurements show that the IQ phase error can be calibrated within 1°,which satisfies the system requirement.
基金Supported by National Natural Science Foundation of China (60472054)
文摘The paper presents a kind of transmission system which employs M-ary Position Phase Shift Keying(MPPSK) to send data and Phase Locked Loop(PLL) based techniques for data retrieve.With a single PLL, MPPSK demodulation is achieved, as well as carrier recovery and symbol synchronization.Firstly, MPPSK modulation method is briefly introduced.2PPSK's PSD expression is given with its optimization result.Orthogonal Phase Detector(PD) and static threshold are used for the purpose of wider phase range and simplicity in demodulation.The data rate is alterable, which is 4.65 kbps for 2PPSK and 9.3 kbps for 4PPSK in the paper.Then some indicative comparisons in Signal to Noise Ratio Symbol Error Rate(SNR-SER) are made among 2PPSK, 3PPSK and 4PPSK, of which 4PPSK has proved to be optimal in ten slots each symbol conditions.And finally, it is demonstrated by system simulations that lower than 10-4 Symbol Error Rate(SER) performance can be obtained at 13 dB symbol SNR.
文摘The design of phase control system in Shanghai Synchrotron Radiation Facility (SSRF) linac is presented in this paper. And digital phase detecting algorithm, the key for phase control system, is fully described. The testing results for phase control system in 100MeV linac are discussed in detail.
基金funded by Project FIS:PI10/00201 (Instituto Carlos III, Ministerio de Economía y Competitividad, Spain)partially supported by European Regional Development Funds (ERDF)
文摘Cetuximab (CTX) is a potent chimeric mouse/human monoclonal antibody (mAb) approved worldwide for treatment of metastatic colorectal cancer. Among the various biological and physical analyses per- formed for full study on this biopharmaceutic, the determination of the concentration preparations throughout manufacturing and subsequent handling in hospital is particularly relevant. In the present work, the study and validation of a method for quantifying intact CTX by reverse-phase high-perfor- mance liquid chromatography with diode array detection ((RP)HPLC/DAD) is presented. With that end, we checked the performance of a chromatographic method for quantifying CTX and conducted a study to validate the method as stability-indicating in accordance with the International Conference on Harmo- nization guidelines (ICH) for biotechnological drugs; therefore, we evaluated linearity, accuracy, preci- sion, detection and quantification limits, robustness and system suitability. The specificity of the method and the robustness of the mAb formulation against external stress factors were estimated by compre- hensive chromatographic analysis by subjecting CTX to several informative stress conditions. As de- monstrated, the method is rapid, accurate, and reproducible for CTX quantification. It was also suc- cessfully used to quantify CTX in a long-term stability study performed under hospital conditions.
文摘A multisampling technique was introduced to the phase error detector of Conventional Digital Tanlocked Loop(C DTL). In this new technique a number of samples ( M ) were taken at nonuniform intervals within one period of the input signal. The novel system is called Multisampling Digital Tanlocked loop(MS DTL). The simulated model on the computer shows that for M =4, the system has a faster locking speed and wider locking in range compared with C DTL.
文摘A method termed hollow fiber liquid phase microextraction (HF-LPME) was utilized to extract three chlo- rophenols, 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP) and 2,4,6- trichlorophenol (2,4,6-TCP), separately from water. The extracted chlorophenols were then separated, identified, and quantified by UV-Vis spectrophotometry with photodiode array detection (UV-Vis/DAD). In the study, experimental con-ditions such as organic phase identity, acceptor phase volume, sample agitation, extraction time, acceptor phase NaOH concentration, donor phase HCl concentration, salt addition, and UV absorption wavelength were optimized. The statistical parameters of the proposed method were investigated under the selected con-ditions. The analytical characteristics of the method such as detection limit, accuracy, precision, relative standard deviation (R.S.D.) and relative standard error (R.S.E.) was calculated. The results showed that the proposed method is simple, rapid, accurate and precise for the analysis of ternary mixtures.