Synthesis of methyl N-phenyl carbamate from dimethyl carbonate and 1,3-diphenyl urea was investigated under atmospheric pressure. The results showed that homogenous catalyst sodium methoxide had the excellent activity...Synthesis of methyl N-phenyl carbamate from dimethyl carbonate and 1,3-diphenyl urea was investigated under atmospheric pressure. The results showed that homogenous catalyst sodium methoxide had the excellent activity to efficiently catalyze the synthesis of methyl N-phenyl carbamate under atmospheric pressure.展开更多
The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu_2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high y...The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu_2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields.This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.展开更多
The enthalpy change of formation reaction of the \%N\%\|phenyl\|\%N\%\+′\|(1,2,3\|thiadiazol\|5\|yl)urea has been determined by a microcalorimeter, using 5\|amino\|1,2,3\|thiadiazole and phenylisocyanate as starting ...The enthalpy change of formation reaction of the \%N\%\|phenyl\|\%N\%\+′\|(1,2,3\|thiadiazol\|5\|yl)urea has been determined by a microcalorimeter, using 5\|amino\|1,2,3\|thiadiazole and phenylisocyanate as starting materials in the solvent of THF. The reaction temperature was kept at 25 ℃. On the basis of experimental and calculated results, the enthalpy change is Δ\-r\%H\%\+\{o-\}\-m=(-142.304±0.390) kJ·mol\+\{-1\}; the reaction order is \%n\%=1/2; the rate constant \%k\%=1.357 9×10\+\{-4\} s\+\{-1\} and the activation free\|energy is Δ\%G\%\+\{o-\}\-m=95.098 \{kJ·mol\+\{-1\}\}. The result indicates that the title reaction takes place easily at room temperature.展开更多
Seven new compounds of the type of N substituted phenyl N′ [6 (2 chlorobenzothiazol)yl]urea,were synthesized with yield 74%～88% by a series of reactions of 2 nitrochlorobenzol with substituted phenylamine respective...Seven new compounds of the type of N substituted phenyl N′ [6 (2 chlorobenzothiazol)yl]urea,were synthesized with yield 74%～88% by a series of reactions of 2 nitrochlorobenzol with substituted phenylamine respectively,the structures of compounds were characterized by elemental analysis, 1HNMR and IR.展开更多
文摘Synthesis of methyl N-phenyl carbamate from dimethyl carbonate and 1,3-diphenyl urea was investigated under atmospheric pressure. The results showed that homogenous catalyst sodium methoxide had the excellent activity to efficiently catalyze the synthesis of methyl N-phenyl carbamate under atmospheric pressure.
文摘The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu_2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields.This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.
文摘The enthalpy change of formation reaction of the \%N\%\|phenyl\|\%N\%\+′\|(1,2,3\|thiadiazol\|5\|yl)urea has been determined by a microcalorimeter, using 5\|amino\|1,2,3\|thiadiazole and phenylisocyanate as starting materials in the solvent of THF. The reaction temperature was kept at 25 ℃. On the basis of experimental and calculated results, the enthalpy change is Δ\-r\%H\%\+\{o-\}\-m=(-142.304±0.390) kJ·mol\+\{-1\}; the reaction order is \%n\%=1/2; the rate constant \%k\%=1.357 9×10\+\{-4\} s\+\{-1\} and the activation free\|energy is Δ\%G\%\+\{o-\}\-m=95.098 \{kJ·mol\+\{-1\}\}. The result indicates that the title reaction takes place easily at room temperature.
文摘Seven new compounds of the type of N substituted phenyl N′ [6 (2 chlorobenzothiazol)yl]urea,were synthesized with yield 74%～88% by a series of reactions of 2 nitrochlorobenzol with substituted phenylamine respectively,the structures of compounds were characterized by elemental analysis, 1HNMR and IR.
