In the past few years,photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix(ECM)-like structure.They can be easily bi...In the past few years,photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix(ECM)-like structure.They can be easily biofabricated through exposure of a photosensitive system composed of photo-crosslinkable hydrogels,photo-initiators and other compounds such as cells and therapeutic molecules,to ultraviolet or visible light.With the development ofbiofabrication methods,many researchers studied the biological applications of photo-crosslinkable hydrogels in tissue engineering,such as vascular,wound dressing and bone engineering.This review highlights the biomaterials for photo-crosslinkable hydrogels,biofabrication techniques and their biological applications in tissue engineering.Meanwhile,the challenges and prospects of photo-crosslinkable hydrogels are discussed as well.展开更多
基金This work was supported by the National Natural Science Foundation of China(Nos.81601613,81771122,81970985,81970984,81901060)Key Research Program of Sichuan Science and Technology Department(Nos.2018SZ0037,2019YFS0142,19YYJC2625).
文摘In the past few years,photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix(ECM)-like structure.They can be easily biofabricated through exposure of a photosensitive system composed of photo-crosslinkable hydrogels,photo-initiators and other compounds such as cells and therapeutic molecules,to ultraviolet or visible light.With the development ofbiofabrication methods,many researchers studied the biological applications of photo-crosslinkable hydrogels in tissue engineering,such as vascular,wound dressing and bone engineering.This review highlights the biomaterials for photo-crosslinkable hydrogels,biofabrication techniques and their biological applications in tissue engineering.Meanwhile,the challenges and prospects of photo-crosslinkable hydrogels are discussed as well.
