A photocalibrated NO donor, N-nitrosated rhodamine 6 G acid (NOG) was designed for monitoring the kinetics or the dose of NO release in a real-time fashion with spectroscopic methods Upon irradiation, a drastic fluore...A photocalibrated NO donor, N-nitrosated rhodamine 6 G acid (NOG) was designed for monitoring the kinetics or the dose of NO release in a real-time fashion with spectroscopic methods Upon irradiation, a drastic fluorescence turn-on was observed, and the NO release from NOG was not interfered by biothiols.Furthermore, this NO donor enabled time-and site-controlled NO release in living cells. With these merits, NOG can be a useful molecular tool in NO biology.展开更多
基金supported by the National Natural Science Foundation of China (Nos. 21475105, 21675123)
文摘A photocalibrated NO donor, N-nitrosated rhodamine 6 G acid (NOG) was designed for monitoring the kinetics or the dose of NO release in a real-time fashion with spectroscopic methods Upon irradiation, a drastic fluorescence turn-on was observed, and the NO release from NOG was not interfered by biothiols.Furthermore, this NO donor enabled time-and site-controlled NO release in living cells. With these merits, NOG can be a useful molecular tool in NO biology.
