Pilomatrixomas are benign tumors derived from hair stromal cells;however,their exact etiology is unknown.A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow,with shedding of...Pilomatrixomas are benign tumors derived from hair stromal cells;however,their exact etiology is unknown.A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow,with shedding of eyebrow hair around the mass,and the shedding area gradually expanded.Surgical removal of the mass failed to prevent eyebrow loss,and the entire left eyebrow shed 6 months postoperatively.Pathology and histology of the biopsy specimen revealed a pilomatrixoma comprising basaloid cells and ghost cells,with basaloid cells expressing high bcl-2 levels.Instead of apoptosis,the emergence and growth of pilomatrixoma-induced microinflammation around the hair follicles of the eyebrow may lead to eyebrow loss.展开更多
A 10-year-old girl presented with a mildly tender mass in the right preauricular region. The mass became larger, and the overlying skin turned purple. There was no clinical response to a course of either cephalexin or...A 10-year-old girl presented with a mildly tender mass in the right preauricular region. The mass became larger, and the overlying skin turned purple. There was no clinical response to a course of either cephalexin or clarithromycin. The remainder of the head and neck examination was normal including normal facial nerve function. Lyme titers and a computed tomographic (CT) scan with contrast of the facial region were obtained. The CT scan demonstrated the lesion to be superficial to the parotid gland. The lyme titer was elevated and doxycycline was begun. The mass appeared to reduce in size after doxycycline treatment, but then grew and turned erythematous. The lesion was surgically excised and was vascular with calcification and cheesy inclusions. The mass was quite close to the skin and the clinical diagnosis at the time of surgery was a pilomatrixoma, which was corroborated on pathological evaluation.展开更多
Dear Editor,I am Dr. Jungyul Park from the Division of Oculoplasty,Department of Ophthalmology,Pusan National University Hospital, Busan, Korea. I am writing to present a case of pilomatrixoma of the upper eyelid in a...Dear Editor,I am Dr. Jungyul Park from the Division of Oculoplasty,Department of Ophthalmology,Pusan National University Hospital, Busan, Korea. I am writing to present a case of pilomatrixoma of the upper eyelid in a 10-month-old baby that first appeared when the baby was 3 months old.展开更多
Pilomatricoma or calcifying epithelioma of Malherbe is a rare benign tumor of the skin and/or the subcutaneous tissue originating from the hair matrix. It is usually seen in children and adolescents, however a smaller...Pilomatricoma or calcifying epithelioma of Malherbe is a rare benign tumor of the skin and/or the subcutaneous tissue originating from the hair matrix. It is usually seen in children and adolescents, however a smaller second peak of onset is seen in the elderly. The head, neck, or upper extremities are the most common anatomical sites of pilomatricomas, being less frequently seen on the trunk and lower extremities, and very rarely have they been diagnosed in the breast. Its malignant counterpart, pilomatrix carcinoma, is rare and found more often in men. Due to its incapacity of regression, treatment consists of surgical excision. We present the case of a man with a pilomatrixoma of the breast, presenting as ACR BI-RADS 4, and we review the literature regarding pilomatrixomas.展开更多
Pilomatrix Carcinoma (PC) is an exceedingly rare neoplasm. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. Although early recognition and treat...Pilomatrix Carcinoma (PC) is an exceedingly rare neoplasm. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. Although early recognition and treatment is paramount in optimization of outcomes for this aggressive carcinoma, the diagnosis is complicated by shared features with its more common benign counterpart. In patients with recurrence or rapid growth of a pilomatrixoma, pilomatrix carcinoma should be considered in the differential diagnosis.展开更多
Pilomatrixoma is an uncommon benign tumor of matrix cells of hair follicles that rarely involves eyelids. Here we present a case of 4-year-old girl who was brought to hospital with swelling in the left upper eyelid wh...Pilomatrixoma is an uncommon benign tumor of matrix cells of hair follicles that rarely involves eyelids. Here we present a case of 4-year-old girl who was brought to hospital with swelling in the left upper eyelid which increased gradually in 1 year. Computed tomography revealed calcified soft tissue mass. The mass was excised successfully and sent for histopathological examination that showed encapsulated tumor composed of eosinophilic ghost cells and basophilic cells suggestive of pilomatrixoma.展开更多
基金supported by the Zhejiang Provincial Natural Science Foundation of China (grant nos. LQ22H150005 and LQ21H150005)
文摘Pilomatrixomas are benign tumors derived from hair stromal cells;however,their exact etiology is unknown.A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow,with shedding of eyebrow hair around the mass,and the shedding area gradually expanded.Surgical removal of the mass failed to prevent eyebrow loss,and the entire left eyebrow shed 6 months postoperatively.Pathology and histology of the biopsy specimen revealed a pilomatrixoma comprising basaloid cells and ghost cells,with basaloid cells expressing high bcl-2 levels.Instead of apoptosis,the emergence and growth of pilomatrixoma-induced microinflammation around the hair follicles of the eyebrow may lead to eyebrow loss.
文摘A 10-year-old girl presented with a mildly tender mass in the right preauricular region. The mass became larger, and the overlying skin turned purple. There was no clinical response to a course of either cephalexin or clarithromycin. The remainder of the head and neck examination was normal including normal facial nerve function. Lyme titers and a computed tomographic (CT) scan with contrast of the facial region were obtained. The CT scan demonstrated the lesion to be superficial to the parotid gland. The lyme titer was elevated and doxycycline was begun. The mass appeared to reduce in size after doxycycline treatment, but then grew and turned erythematous. The lesion was surgically excised and was vascular with calcification and cheesy inclusions. The mass was quite close to the skin and the clinical diagnosis at the time of surgery was a pilomatrixoma, which was corroborated on pathological evaluation.
文摘Dear Editor,I am Dr. Jungyul Park from the Division of Oculoplasty,Department of Ophthalmology,Pusan National University Hospital, Busan, Korea. I am writing to present a case of pilomatrixoma of the upper eyelid in a 10-month-old baby that first appeared when the baby was 3 months old.
文摘Pilomatricoma or calcifying epithelioma of Malherbe is a rare benign tumor of the skin and/or the subcutaneous tissue originating from the hair matrix. It is usually seen in children and adolescents, however a smaller second peak of onset is seen in the elderly. The head, neck, or upper extremities are the most common anatomical sites of pilomatricomas, being less frequently seen on the trunk and lower extremities, and very rarely have they been diagnosed in the breast. Its malignant counterpart, pilomatrix carcinoma, is rare and found more often in men. Due to its incapacity of regression, treatment consists of surgical excision. We present the case of a man with a pilomatrixoma of the breast, presenting as ACR BI-RADS 4, and we review the literature regarding pilomatrixomas.
文摘Pilomatrix Carcinoma (PC) is an exceedingly rare neoplasm. Although it has been described at various anatomical sites, fewer than 25 cases have been reported in the face and scalp. Although early recognition and treatment is paramount in optimization of outcomes for this aggressive carcinoma, the diagnosis is complicated by shared features with its more common benign counterpart. In patients with recurrence or rapid growth of a pilomatrixoma, pilomatrix carcinoma should be considered in the differential diagnosis.
文摘Pilomatrixoma is an uncommon benign tumor of matrix cells of hair follicles that rarely involves eyelids. Here we present a case of 4-year-old girl who was brought to hospital with swelling in the left upper eyelid which increased gradually in 1 year. Computed tomography revealed calcified soft tissue mass. The mass was excised successfully and sent for histopathological examination that showed encapsulated tumor composed of eosinophilic ghost cells and basophilic cells suggestive of pilomatrixoma.
