Hydrogen peroxide(H_(2)O_(2))is an important chemical substance produced in the metabolic process of organisms.Excess or less production could lead to serious effects on the body.Therefore,the development of advanced ...Hydrogen peroxide(H_(2)O_(2))is an important chemical substance produced in the metabolic process of organisms.Excess or less production could lead to serious effects on the body.Therefore,the development of advanced technology to accurately detect the content of H_(2)O_(2) is of great significance.Herein,we developed a new ratiometric SERS nanoprobe based on shell-isolated nanoparticles(SHINs)for rapidly quantitative detection of H_(2)O_(2)-Because of the small Raman cross-section of H_(2)O_(2),the ratiometric nanoprobe is an effective method for indirect detection of H_(2)O_(2),which is designed based on the reaction of p-mercaptophenylboric acid(MPB)with H_(2)O_(2) to form p-mercaptophenol(MP).Meanwhile,the nanoprobe was used to achieve quantitative detection of H_(2)O_(2) and applied in quantitative detection of actual sample-glucose,whose linear correlation coefficient could reach 0.9947 and 0.9812,respectively.This method expands the application of SERS technology,especially provides a reference for the detection of molecules with small Raman cross-section.展开更多
基金Supported by the National Natural Science Foundation of China(21925404)the Science and Technology Planning Project of Fujian Province(2019Y4001)。
文摘Hydrogen peroxide(H_(2)O_(2))is an important chemical substance produced in the metabolic process of organisms.Excess or less production could lead to serious effects on the body.Therefore,the development of advanced technology to accurately detect the content of H_(2)O_(2) is of great significance.Herein,we developed a new ratiometric SERS nanoprobe based on shell-isolated nanoparticles(SHINs)for rapidly quantitative detection of H_(2)O_(2)-Because of the small Raman cross-section of H_(2)O_(2),the ratiometric nanoprobe is an effective method for indirect detection of H_(2)O_(2),which is designed based on the reaction of p-mercaptophenylboric acid(MPB)with H_(2)O_(2) to form p-mercaptophenol(MP).Meanwhile,the nanoprobe was used to achieve quantitative detection of H_(2)O_(2) and applied in quantitative detection of actual sample-glucose,whose linear correlation coefficient could reach 0.9947 and 0.9812,respectively.This method expands the application of SERS technology,especially provides a reference for the detection of molecules with small Raman cross-section.
