Purpose: Cylindrical ionization chambers as the PinPoint and the CC01 have high-spatial resolution and cylindrical symmetry in relevance to small fields. Dosimetry of newly advanced technologies that include non-copla...Purpose: Cylindrical ionization chambers as the PinPoint and the CC01 have high-spatial resolution and cylindrical symmetry in relevance to small fields. Dosimetry of newly advanced technologies that include non-coplanar beams, such as in Gamma-Knife, VMAT and IMRT treatment plans, the angular dependence of the ion chamber is essential. Therefore in this study we simulated two common used ion chambers using a Monte Carlo method. Methods: The angular dependence for the CC01 and the PinPoint were calculated for a vast angular range in a cylindrical water phantom for two LINAC photon beams, 6 MV and 15 MV. The calculations were performed for fully structural description of each ion chamber using Monte Carlo code, in order to reveal unsymmetrical response dose higher than 2% in medical applications. The calculated dose response, for the CC01 ion chamber, was validated with measurements. Results: The CC01 ion chamber showed a very small angular dependence compared to the PinPoint ion chamber. The relative angular dependence amplitude of the PinPoint was about 12% in the range of 0° - 110°. Conclusions: The differences in the ion chambers structure led to the variations in the relative angular dependence amplitude. Therefore, when choosing a detector, not only the volume of the ionization chamber but also its structure must be taken into consideration.展开更多
In description logic,axiom pinpointing is used to explore defects in ontologies and identify hidden justifications for a logical consequence.In recent years,SAT-based axiom pinpointing techniques,which rely on the enu...In description logic,axiom pinpointing is used to explore defects in ontologies and identify hidden justifications for a logical consequence.In recent years,SAT-based axiom pinpointing techniques,which rely on the enumeration of minimal unsatisfiable subsets(MUSes)of pinpointing formulas,have gained increasing attention.Compared with traditional Tableau-based reasoning approaches,SAT-based techniques are more competitive when computing justifications for consequences in large-scale lightweight description logic ontologies.In this article,we propose a novel enumeration justification algorithm,working with a replicated driver.The replicated driver discovers new justifications from the explored justifications through cheap literals resolution,which avoids frequent calls of SAT solver.Moreover,when the use of SAT solver is inevitable,we adjust the strategies and heuristic parameters of the built-in SAT solver of axiom pinpointing algorithm.The adjusted SAT solver is able to improve the checking efficiency of unexplored sub-formulas.Our proposed method is implemented as a tool named RDMinA.The experimental results show that RDMinA outperforms the existing axiom pinpointing tools on practical biomedical ontologies such as Gene,Galen,NCI and Snomed-CT.展开更多
文摘Purpose: Cylindrical ionization chambers as the PinPoint and the CC01 have high-spatial resolution and cylindrical symmetry in relevance to small fields. Dosimetry of newly advanced technologies that include non-coplanar beams, such as in Gamma-Knife, VMAT and IMRT treatment plans, the angular dependence of the ion chamber is essential. Therefore in this study we simulated two common used ion chambers using a Monte Carlo method. Methods: The angular dependence for the CC01 and the PinPoint were calculated for a vast angular range in a cylindrical water phantom for two LINAC photon beams, 6 MV and 15 MV. The calculations were performed for fully structural description of each ion chamber using Monte Carlo code, in order to reveal unsymmetrical response dose higher than 2% in medical applications. The calculated dose response, for the CC01 ion chamber, was validated with measurements. Results: The CC01 ion chamber showed a very small angular dependence compared to the PinPoint ion chamber. The relative angular dependence amplitude of the PinPoint was about 12% in the range of 0° - 110°. Conclusions: The differences in the ion chambers structure led to the variations in the relative angular dependence amplitude. Therefore, when choosing a detector, not only the volume of the ionization chamber but also its structure must be taken into consideration.
基金supported by the National Natural Science Foundation of China(NSFC)(Grant Nos.42050103,62076108,and U19A2061).
文摘In description logic,axiom pinpointing is used to explore defects in ontologies and identify hidden justifications for a logical consequence.In recent years,SAT-based axiom pinpointing techniques,which rely on the enumeration of minimal unsatisfiable subsets(MUSes)of pinpointing formulas,have gained increasing attention.Compared with traditional Tableau-based reasoning approaches,SAT-based techniques are more competitive when computing justifications for consequences in large-scale lightweight description logic ontologies.In this article,we propose a novel enumeration justification algorithm,working with a replicated driver.The replicated driver discovers new justifications from the explored justifications through cheap literals resolution,which avoids frequent calls of SAT solver.Moreover,when the use of SAT solver is inevitable,we adjust the strategies and heuristic parameters of the built-in SAT solver of axiom pinpointing algorithm.The adjusted SAT solver is able to improve the checking efficiency of unexplored sub-formulas.Our proposed method is implemented as a tool named RDMinA.The experimental results show that RDMinA outperforms the existing axiom pinpointing tools on practical biomedical ontologies such as Gene,Galen,NCI and Snomed-CT.