A double-well potential model is proposed for the pionic deuterium that enables to calculate the energy split, the potential barrier height and estimate the pion tetrahedron edge length. We propose that pion tetrahedr...A double-well potential model is proposed for the pionic deuterium that enables to calculate the energy split, the potential barrier height and estimate the pion tetrahedron edge length. We propose that pion tetrahedrons, π<sup>Td</sup> = u<sub>d</sub>~</sup>dũ, play a central role in the Yukawa interaction by enabling quark exchange reactions between protons and neutrons by tunneling through a potential barrier. A vacuum polarization Feynman diagram is proposed for the π<sup>Td</sup> having chains of fermion loops for the two valence quarks and anti-quarks connected by gluons. With a higher order vacuum polarization diagram, the d and u quark loops are interleaved and the chiral symmetry is broken dynamically. The proposed π<sup>Td</sup> vacuum polarization integral does not diverge in both the IR and UV limits and vanishes in the limit of an infinite pion tetrahedron condensate. We propose a new Delbruck scattering Feynman diagram that includes d and u quark and anti-quark interleaved loops. We further propose that conversion of gravitons to photons may occur via quark and anti-quark loops that describe the pion tetrahedrons dynamics in the vacuum and may also transfer gravitational waves.展开更多
This article looks for the necessary conditions to use Deuterium-Deuterium (D-D) fusion for a large power plant. At the moment, for nearly all the projects (JET, ITER…) only the Deuterium-Tritium (D-T) fuel is consid...This article looks for the necessary conditions to use Deuterium-Deuterium (D-D) fusion for a large power plant. At the moment, for nearly all the projects (JET, ITER…) only the Deuterium-Tritium (D-T) fuel is considered for a power plant. However, as shown in this article, even if a D-D reactor would be necessarily much bigger than a D-T reactor due to the much weaker fusion reactivity of the D-D fusion compared to the D-T fusion, a D-D reactor size would remain under an acceptable size. Indeed, a D-D power plant would be necessarily large and powerful, i.e. the net electric power would be equal to a minimum of 1.2 GWe and preferably above 10 GWe. A D-D reactor would be less complex than a D-T reactor as it is not necessary to obtain Tritium from the reactor itself. It is proposed the same type of reactor yet proposed by the author in a previous article, i.e. a Stellarator “racetrack” magnetic loop. The working of this reactor is continuous. It is reminded that the Deuterium is relatively abundant on the sea water, and so it constitutes an almost inexhaustible source of energy. Thanks to secondary fusions (D-T and D-He3) which both occur at an appreciable level above 100 keV, plasma can stabilize around such high equilibrium energy (i.e. between 100 and 150 keV). The mechanical gain (Q) of such reactor increases with the internal pipe radius, up to 4.5 m. A radius of 4.5 m permits a mechanical gain (Q) of about 17 which thanks to a modern thermo-dynamical conversion would lead to convert about 21% of the thermal power issued from the D-D reactor in a net electric power of 20 GWe. The goal of the article is to create a physical model of the D-D reactor so as to estimate this one without the need of a simulator and finally to estimate the dimensions, power and yield of such D-D reactor for different net electrical powers. The difficulties of the modeling of such reactor are listed in this article and would certainly be applicable to a future D-He3 reactor, if any.展开更多
Deuterium labeling techniques are widely utilized as efficient tools to study the absorption,distribution,metabolism,and excretion(ADME)of pharmaceuticals.Moreover,deuterium‐labeled drugs are expected to prolong the ...Deuterium labeling techniques are widely utilized as efficient tools to study the absorption,distribution,metabolism,and excretion(ADME)of pharmaceuticals.Moreover,deuterium‐labeled drugs are expected to prolong the half‐life of drug metabolism,enhance the efficacy of drugs,close metabolic sites,and decrease side effects.Thus,there is a rising demand for the practical construction of deuterium‐labeled drugs and their intermediates under mild conditions.This paper timely provides an overview of the recent advances in both photo‐and electro‐catalytic mild and selective deuteration of fine chemicals and pharmaceuticals with low‐cost and sustainable deuterium source.Three types of deuteration strategies are discussed according to the deuteration mode,named deuterium atom transfer strategy,deuterium atom abstraction strategy and deuterated water splitting strategy respectively.The application scope and mechanistic insights are discussed comprehensively.Finally,the perspective on the challenges and future development trends for photo‐and electro‐catalytic deuteration strategies are also presented.展开更多
In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants （k = AT//kP...In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants （k = AT//kP） in both nitrogen and deuterium atmosphere we found an optimum current （8 A） and a deuterium pressure （9 x 104 Pa） in which the system could release a maximum excess power （more than 80 W）. The reproducibility was 16/16 and the excess energy released in the longest experiment was about 300 MJ within 40 days, which was corresponding to 104 eV for each palladium atom. Analysis of the palladium surface with a SEM （scanning electron microscopy） and an EDS （energy dispersive spectrometer） revealed that some new surface topographical feature with concentrations of unexpected elements （such as Ag, Sn, Pb and Ca） appeared after the current triggering. The results implied that the excess heat might come from a nuclear transmutation.展开更多
The deuteration of organic compounds has attracted more attentions in recent years for the potential applications in new drug discovery and synthetic chemistry.For this purpose,many efficient deuterium labeling method...The deuteration of organic compounds has attracted more attentions in recent years for the potential applications in new drug discovery and synthetic chemistry.For this purpose,many efficient deuterium labeling methodologies have been developed,including hydrogen isotope exchange(HIE),reductive deuteration,and dehalogenative deuteration that allow for the synthesis of selectively deuterated compounds.In the last few years,great breakthroughs in selective isotope labeling have been achieved and the interest in new methodologies for the deuteration of organic molecules is rising.In this review,we summarized the recent developments in the selective deuteration of organic molecules since 2021.Several types of key processes in deuterium incorporation reactions,including H/D exchange,reductive deuteration and dehalogenative deuteration,are introduced and discussed.展开更多
文摘A double-well potential model is proposed for the pionic deuterium that enables to calculate the energy split, the potential barrier height and estimate the pion tetrahedron edge length. We propose that pion tetrahedrons, π<sup>Td</sup> = u<sub>d</sub>~</sup>dũ, play a central role in the Yukawa interaction by enabling quark exchange reactions between protons and neutrons by tunneling through a potential barrier. A vacuum polarization Feynman diagram is proposed for the π<sup>Td</sup> having chains of fermion loops for the two valence quarks and anti-quarks connected by gluons. With a higher order vacuum polarization diagram, the d and u quark loops are interleaved and the chiral symmetry is broken dynamically. The proposed π<sup>Td</sup> vacuum polarization integral does not diverge in both the IR and UV limits and vanishes in the limit of an infinite pion tetrahedron condensate. We propose a new Delbruck scattering Feynman diagram that includes d and u quark and anti-quark interleaved loops. We further propose that conversion of gravitons to photons may occur via quark and anti-quark loops that describe the pion tetrahedrons dynamics in the vacuum and may also transfer gravitational waves.
文摘This article looks for the necessary conditions to use Deuterium-Deuterium (D-D) fusion for a large power plant. At the moment, for nearly all the projects (JET, ITER…) only the Deuterium-Tritium (D-T) fuel is considered for a power plant. However, as shown in this article, even if a D-D reactor would be necessarily much bigger than a D-T reactor due to the much weaker fusion reactivity of the D-D fusion compared to the D-T fusion, a D-D reactor size would remain under an acceptable size. Indeed, a D-D power plant would be necessarily large and powerful, i.e. the net electric power would be equal to a minimum of 1.2 GWe and preferably above 10 GWe. A D-D reactor would be less complex than a D-T reactor as it is not necessary to obtain Tritium from the reactor itself. It is proposed the same type of reactor yet proposed by the author in a previous article, i.e. a Stellarator “racetrack” magnetic loop. The working of this reactor is continuous. It is reminded that the Deuterium is relatively abundant on the sea water, and so it constitutes an almost inexhaustible source of energy. Thanks to secondary fusions (D-T and D-He3) which both occur at an appreciable level above 100 keV, plasma can stabilize around such high equilibrium energy (i.e. between 100 and 150 keV). The mechanical gain (Q) of such reactor increases with the internal pipe radius, up to 4.5 m. A radius of 4.5 m permits a mechanical gain (Q) of about 17 which thanks to a modern thermo-dynamical conversion would lead to convert about 21% of the thermal power issued from the D-D reactor in a net electric power of 20 GWe. The goal of the article is to create a physical model of the D-D reactor so as to estimate this one without the need of a simulator and finally to estimate the dimensions, power and yield of such D-D reactor for different net electrical powers. The difficulties of the modeling of such reactor are listed in this article and would certainly be applicable to a future D-He3 reactor, if any.
文摘Deuterium labeling techniques are widely utilized as efficient tools to study the absorption,distribution,metabolism,and excretion(ADME)of pharmaceuticals.Moreover,deuterium‐labeled drugs are expected to prolong the half‐life of drug metabolism,enhance the efficacy of drugs,close metabolic sites,and decrease side effects.Thus,there is a rising demand for the practical construction of deuterium‐labeled drugs and their intermediates under mild conditions.This paper timely provides an overview of the recent advances in both photo‐and electro‐catalytic mild and selective deuteration of fine chemicals and pharmaceuticals with low‐cost and sustainable deuterium source.Three types of deuteration strategies are discussed according to the deuteration mode,named deuterium atom transfer strategy,deuterium atom abstraction strategy and deuterated water splitting strategy respectively.The application scope and mechanistic insights are discussed comprehensively.Finally,the perspective on the challenges and future development trends for photo‐and electro‐catalytic deuteration strategies are also presented.
文摘In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants （k = AT//kP） in both nitrogen and deuterium atmosphere we found an optimum current （8 A） and a deuterium pressure （9 x 104 Pa） in which the system could release a maximum excess power （more than 80 W）. The reproducibility was 16/16 and the excess energy released in the longest experiment was about 300 MJ within 40 days, which was corresponding to 104 eV for each palladium atom. Analysis of the palladium surface with a SEM （scanning electron microscopy） and an EDS （energy dispersive spectrometer） revealed that some new surface topographical feature with concentrations of unexpected elements （such as Ag, Sn, Pb and Ca） appeared after the current triggering. The results implied that the excess heat might come from a nuclear transmutation.
基金the National Key R&D Program of China(No.2021YFA1500100,A.L.)National Natural Science Foundation of China(22031008,A.L.+1 种基金212200007,W.L.)Science Foundation of Wuhan(2020010601012192,A.L.).
文摘The deuteration of organic compounds has attracted more attentions in recent years for the potential applications in new drug discovery and synthetic chemistry.For this purpose,many efficient deuterium labeling methodologies have been developed,including hydrogen isotope exchange(HIE),reductive deuteration,and dehalogenative deuteration that allow for the synthesis of selectively deuterated compounds.In the last few years,great breakthroughs in selective isotope labeling have been achieved and the interest in new methodologies for the deuteration of organic molecules is rising.In this review,we summarized the recent developments in the selective deuteration of organic molecules since 2021.Several types of key processes in deuterium incorporation reactions,including H/D exchange,reductive deuteration and dehalogenative deuteration,are introduced and discussed.
