Three new bicyclooctanoid neolignans, kadsurenin A, kadsurenin B and kadsurenin C were isolated from Piper kadsura (Choisy) Ohwi. Based on the spectroscopic analysis (UV, JR, MS, NMR, and X-ray), their structures were...Three new bicyclooctanoid neolignans, kadsurenin A, kadsurenin B and kadsurenin C were isolated from Piper kadsura (Choisy) Ohwi. Based on the spectroscopic analysis (UV, JR, MS, NMR, and X-ray), their structures were established as 7R, 8R, 3'S, 4'R, 5'R-△^(s')-3,4-methyienedioxy-5'-methoxy-4'-acetyloxy-2',3',4',5'-tetrahydro-2'-oxo-7.3',8.5'-neolignan; 7R, 8R, 3'S, 4'R, 5'R-△^(s')-3, 4-methylenedioxy-5'-methoxy-4'-hydroxy-2',3',4',5'-tetrahydro-2'-oxo-7. 3', 8. 5'-neolignan and 7R, 8R. 3'S, 4'R, 5'R-△^(s')-3, 4, 5'-trimethoxy-4'-hydroxy- 2', 3', 4', 5'-tetrahydro-2'-oxo-7. 3', 8. 5'-neolignan respectively.展开更多
Two new neolignans, Kadsuranin G and Kadsuranin H, were isolated from Piper Kadsura (Choisy) Ohwi. Baaed on the spectroscopic analysis (UV, IR, MS, NNR, and X-ray) and chemical reactions, their structures were establi...Two new neolignans, Kadsuranin G and Kadsuranin H, were isolated from Piper Kadsura (Choisy) Ohwi. Baaed on the spectroscopic analysis (UV, IR, MS, NNR, and X-ray) and chemical reactions, their structures were established as 7R,BR,1'S,2'R,3'5-△^(8')-3,4,5'-trimethoxy-2'-hydroxy-1',2',3',4'-tetrahydro-4'-oxo-7,3',8,1'-neolignan and 7R,8R,1'S,2'R,3'S-△^(8')-3,4,5'-trimethoxy-2'-acetyloxy-1',2',3',4'-tetrahydro-4'-oxo-7,3',8,1'-neolignan.展开更多
Two new bicyclo[3,2,1]octanoid neolignans,named as kadsurenin I and kadsurenin J were isolated from Piper kadsura(Choiey)Ohwi.Based on the spectros- copic analysis(UV,IR,MS and NMR)and chemical derivatization,their st...Two new bicyclo[3,2,1]octanoid neolignans,named as kadsurenin I and kadsurenin J were isolated from Piper kadsura(Choiey)Ohwi.Based on the spectros- copic analysis(UV,IR,MS and NMR)and chemical derivatization,their structures were established as 7R,8R,1'R,2'S,3'R-Δ~s'-3,4,5'-trimethoxy-2'-hydroxy-1',2',3',4'- tetrahydro-4'-oxo-7.3',8.1'-neolignan and 7R,8R,1'R,2'S,3'R-Δ~s'-3,4,5'-trimethoxy -2'-acetoxy-1',2',3',4'-tetrabydro-4'-oxo-7.3',8.1'-neolignan respectively.展开更多
基金The project was supported by National Natural Science Foundation of China
文摘Three new bicyclooctanoid neolignans, kadsurenin A, kadsurenin B and kadsurenin C were isolated from Piper kadsura (Choisy) Ohwi. Based on the spectroscopic analysis (UV, JR, MS, NMR, and X-ray), their structures were established as 7R, 8R, 3'S, 4'R, 5'R-△^(s')-3,4-methyienedioxy-5'-methoxy-4'-acetyloxy-2',3',4',5'-tetrahydro-2'-oxo-7.3',8.5'-neolignan; 7R, 8R, 3'S, 4'R, 5'R-△^(s')-3, 4-methylenedioxy-5'-methoxy-4'-hydroxy-2',3',4',5'-tetrahydro-2'-oxo-7. 3', 8. 5'-neolignan and 7R, 8R. 3'S, 4'R, 5'R-△^(s')-3, 4, 5'-trimethoxy-4'-hydroxy- 2', 3', 4', 5'-tetrahydro-2'-oxo-7. 3', 8. 5'-neolignan respectively.
文摘Two new neolignans, Kadsuranin G and Kadsuranin H, were isolated from Piper Kadsura (Choisy) Ohwi. Baaed on the spectroscopic analysis (UV, IR, MS, NNR, and X-ray) and chemical reactions, their structures were established as 7R,BR,1'S,2'R,3'5-△^(8')-3,4,5'-trimethoxy-2'-hydroxy-1',2',3',4'-tetrahydro-4'-oxo-7,3',8,1'-neolignan and 7R,8R,1'S,2'R,3'S-△^(8')-3,4,5'-trimethoxy-2'-acetyloxy-1',2',3',4'-tetrahydro-4'-oxo-7,3',8,1'-neolignan.
文摘Two new bicyclo[3,2,1]octanoid neolignans,named as kadsurenin I and kadsurenin J were isolated from Piper kadsura(Choiey)Ohwi.Based on the spectros- copic analysis(UV,IR,MS and NMR)and chemical derivatization,their structures were established as 7R,8R,1'R,2'S,3'R-Δ~s'-3,4,5'-trimethoxy-2'-hydroxy-1',2',3',4'- tetrahydro-4'-oxo-7.3',8.1'-neolignan and 7R,8R,1'R,2'S,3'R-Δ~s'-3,4,5'-trimethoxy -2'-acetoxy-1',2',3',4'-tetrabydro-4'-oxo-7.3',8.1'-neolignan respectively.
