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Proximate composition, nutritional values and phytochemical screening of Piper retrofractum vahl. fruits
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作者 Nurul Jadid Byan Arasyi Arraniry +4 位作者 Dewi Hidayati Kristanti Indah Purwani Wiwi Wikanta Sylviana Rosyda Hartanti Rizka Yuanita Rachman 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2018年第1期37-43,共7页
Objective: To investigate the proximate and mineral composition of the Piper retrofractum(P. retrofractum) vahl. Fruit and to evaluate its total alkaloids, phenol and flavonoid. Methods: The proximate composition of P... Objective: To investigate the proximate and mineral composition of the Piper retrofractum(P. retrofractum) vahl. Fruit and to evaluate its total alkaloids, phenol and flavonoid. Methods: The proximate composition of P. retrofractum fruit was ananlyzed using standard protocols according to Indonesian Standard and Association of Official Analytical Chemist. Meanwhile, mineral composition of the fruit was analyzed using inductively coupled plasma-mass spectrometry. Phytochemical screening and quantification were performed using standard protocols according to Harborn and spectrophotometric methods. Results: The results showed that P. retrofractum fruit contained carbohydrate(63.4%), crude protein(11.4%), total ash(4.29%), dietary fiber(28.8%) and total fat(2.97%). The fruit also contained calcium, copper, iron, magnesium, phosphor, potassium, sodium and zinc in different concentrations. Additionally, quinone, sterol, glycosides and alkaloid were detected in both n-hexane and ethyl acetate extracts. Moreover, tannin was presented also in ethylacetate and methanol extracts. Meanwhile, methanol extract contained sterol, glycosides, flavones, tannin and alkaloid. The results also revealed that methanol extract of the fruit contained highest phenol compared to other extract. Finally, small quantity of flavonoid(0.060 0%±0.000 2%) was observed. Conclusions: The overall results show that P. retrofractum contains potential nutritional and phytochemicals values, which support their function for pharmaceutical purposes. 展开更多
关键词 Mineral composition piper retrofractum vahl. Phytochemical analysis Proximate composition
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New Amides and Phenylpropanoid Glucosides from the Fruits of Piper retrofractum
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作者 Rong Tang Ya-Qiong Zhang +6 位作者 Dong-Bao Hu Xue-Fei Yang Jun Yang Myint Myint San Thaung Naing Oo Yi Kong Yue-Hu Wang 《Natural Products and Bioprospecting》 CAS 2019年第3期231-241,共11页
Two new amides(E)-N-cinnamoyl-2-methoxypiperidine(1)and(R)-1-(2-oxopyrrolidin-3-yl)-5,6-dihydropyridin-2(1H)-one(2),four new amide glucosides,retrofractosides A-D(3-6),and two new phenylpropanoid glucosides,retrofract... Two new amides(E)-N-cinnamoyl-2-methoxypiperidine(1)and(R)-1-(2-oxopyrrolidin-3-yl)-5,6-dihydropyridin-2(1H)-one(2),four new amide glucosides,retrofractosides A-D(3-6),and two new phenylpropanoid glucosides,retrofractosides E(7)and F(8),together with 24 known compounds(9-32)were isolated from the fruits of Piper retrofractum.The chemical structures of these new compounds were elucidated based on extensive spectroscopic analysis.All of these isolates(1-32)were evaluated for inhibitory activity against mouse platelet aggregation induced by the peptide AYPGKF-NH2.(E)-N-(Tetrahydro-2H-pyran-2-yl)cinnamamide(9)showed a weak inhibitory efect,with an inhibition ratio of 52.0%at a concentration of 150μM. 展开更多
关键词 piper retrofractum piperACEAE Antiplatelet AMIDES PHENYLPROPANOIDS
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