AIM: To clarify whether subclassification of the type VI pit pattern on the basis of magnifying colonoscopy findings is useful in determining the type and depth of invasion of colorectal neoplasms.METHODS: We retrospe...AIM: To clarify whether subclassification of the type VI pit pattern on the basis of magnifying colonoscopy findings is useful in determining the type and depth of invasion of colorectal neoplasms.METHODS: We retrospectively analyzed 272 colorectal neoplasms (117 dysplasias and 155 submucosal invasive carcinomas; 228 patients) with a type V pit pattern [type VI, n = 202; type VN, n = 70 (Kudo and Tsuruta classification system)]. We divided lesions with a type VI pit pattern into two subclasses, mildly irregular lesions and severely irregular lesions, according to the prominent and detailed magnifying colonoscopy findings. We examined the relation between these two subclasses and histology/invasion depth.RESULTS: One hundred and four lesions (51.5%) were judged to be mildly irregular, and 98 lesions (48.5%) were judged to be severely irregular. Ninety-seven (93.3%) mildly irregular lesions showed dysplasias or submucosal invasion of less than 1000 μm (SM < 1000 μm). Fifty-five (56.1%) severely irregular lesions showed submucosal invasion equal to or deeper than 1000 μm (SM ≥ 1000 μm). Mild irregularity was found significantly more often in dysplasias or lesions with SM < 1000 μm than in lesions with SM ≥ 1000 μm (P < 0.01).CONCLUSION: Subclassification of the type VI pit pattern is useful for identifying dysplasias or lesions with SM < 1000 μm.展开更多
BACKGROUND Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging(NBI) Expert Team(JNET) classification is a novel NBI ma...BACKGROUND Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging(NBI) Expert Team(JNET) classification is a novel NBI magnifying endoscopic classification that focuses on the vessel, and surface patterns.AIM To determine the diagnostic efficacy of each category of the JNET and Pit pattern classifications for colorectal lesions.METHODS A systematic literature search was performed using PubMed, Embase, the Cochrane Library, and Web of Science databases. The pooled sensitivity, specificity, diagnostic odds ratio, and area under the summary receiver operating characteristic curve of each category of the JNET and Pit pattern classifications were calculated.RESULTS A total of 19227 colorectal lesions in 31 studies were included. The diagnostic performance of the JNET classification was equivalent to the Pit pattern classification in each corresponding category. The pooled sensitivity, specificity,and area under the curve(AUC) for each category of the JNET classification were as follows: 0.73(95%CI: 0.55-0.85), 0.99(95%CI: 0.97-1.00), and 0.97(95%CI: 0.95-0.98), respectively, for Type 1;0.88(95%CI: 0.78-0.94), 0.72(95%CI: 0.64-0.79), and 0.84(95%CI: 0.81-0.87), respectively, for Type 2 A;0.56(95%CI: 0.47-0.64), 0.91(95%CI: 0.79-0.96), and 0.72(95%CI: 0.68-0.76), respectively, for Type 2 B;0.51(95%CI: 0.42-0.61), 1.00(95%CI: 1.00-1.00), and 0.90(95%CI: 0.87-0.93), respectively, for Type 3.CONCLUSION This meta-analysis suggests that the diagnostic efficacy of the JNET classification may be equivalent to that of the Pit pattern classification. However, due to its simpler and clearer clinical application, the JNET classification should be promoted for the classification of colorectal lesions, and to guide the treatment strategy.展开更多
Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoi...Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoil components, which mainly comes from different weaving methods and different braided tow thickness. However, few people have studied the influence of surface morphology of ceramic matrix composites(CMCs) on the development of boundary layer and the resulting flow loss. In this paper, Tex Gen is used to generate different surface morphology structures of ceramic matrix composites(CMCs), and the surface flow characteristics of corresponding CMCs plates are numerically studied. It is found that the slope of the displacement thickness of the woven surface first increases and then decreases in the whole transition interval. Thicker braided tow thickness and denser braiding method will induce earlier flow transition phenomenon and produce greater flow loss;The flow loss on the surface of CMCs plate is mainly composed of the vortex loss in the pit and the boundary layer loss outside the pit, and the boundary layer loss is dominant. The weaving methods has a greater influence on the flow state and flow loss of the boundary layer.展开更多
In a reserved forest parcel in a virgin eastern Hyrcanian mixed beech forest,80 ha was surveyed to determine the pit and mound topography,canopy gaps and dead trees.The aim was to investigate the spatial patterns and ...In a reserved forest parcel in a virgin eastern Hyrcanian mixed beech forest,80 ha was surveyed to determine the pit and mound topography,canopy gaps and dead trees.The aim was to investigate the spatial patterns and correlation of pit and mound features with canopy gaps.Seventy-five canopy gaps and 61 pit and mound features were identified.The univariate first order nearest neighbor(R_(CE))and bivariate second order test(Ripley’s K)statistic were applied.R_(CE) statistics highlighted a general aggregation pattern for canopy gaps and pits and mounds,while pits and mounds alone were more clumped.Distances between canopy gaps were 130 m average,whereas distances between pit and mound features and dead trees were 60 and 78 m,respectively.Spatial positive correlation of canopy gaps with pits and mounds were observed with all distances.The result of spatial correlations between canopy gaps with pits and mounds confirmed that windthrows cause micro successions in fallen tree ecosystem-scale correlated with gap phase dynamics in the forest community-scale.展开更多
Based on the externality theory and the environmental value theory, the hypothesis of charging for waste dumping of open-pit metal mines was put forth. The charging methods were designed according to the characteristi...Based on the externality theory and the environmental value theory, the hypothesis of charging for waste dumping of open-pit metal mines was put forth. The charging methods were designed according to the characteristics of waste dumping of openpit metal mines, including charging based on the dumping amount of the total waste, multi-charging factors, exceeding standard punishment charging, and so on. The main charging parameter is based on the dumping area rather than the total amount of waste dumping. The charging model of waste dumping of open-pit mines was formulated, and the charging rate was divided into two parts, i.e., the standard charging rate and the differential charging rate. The standard charging rate was derived using the equilibrium dynamic model, whereas the differential one was obtained by establishing the fuzzy synthesized evaluation model.展开更多
基金a grant from the Japanese Society of Gastro-enterological Endoscopy, Chugoku Branch
文摘AIM: To clarify whether subclassification of the type VI pit pattern on the basis of magnifying colonoscopy findings is useful in determining the type and depth of invasion of colorectal neoplasms.METHODS: We retrospectively analyzed 272 colorectal neoplasms (117 dysplasias and 155 submucosal invasive carcinomas; 228 patients) with a type V pit pattern [type VI, n = 202; type VN, n = 70 (Kudo and Tsuruta classification system)]. We divided lesions with a type VI pit pattern into two subclasses, mildly irregular lesions and severely irregular lesions, according to the prominent and detailed magnifying colonoscopy findings. We examined the relation between these two subclasses and histology/invasion depth.RESULTS: One hundred and four lesions (51.5%) were judged to be mildly irregular, and 98 lesions (48.5%) were judged to be severely irregular. Ninety-seven (93.3%) mildly irregular lesions showed dysplasias or submucosal invasion of less than 1000 μm (SM < 1000 μm). Fifty-five (56.1%) severely irregular lesions showed submucosal invasion equal to or deeper than 1000 μm (SM ≥ 1000 μm). Mild irregularity was found significantly more often in dysplasias or lesions with SM < 1000 μm than in lesions with SM ≥ 1000 μm (P < 0.01).CONCLUSION: Subclassification of the type VI pit pattern is useful for identifying dysplasias or lesions with SM < 1000 μm.
基金Supported by the Natural Science Foundation of Zhejiang Province,No. LQ20H160061Medical Health Science and Technology Project of Zhejiang Provincial Health Commission,No. 2018255969。
文摘BACKGROUND Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging(NBI) Expert Team(JNET) classification is a novel NBI magnifying endoscopic classification that focuses on the vessel, and surface patterns.AIM To determine the diagnostic efficacy of each category of the JNET and Pit pattern classifications for colorectal lesions.METHODS A systematic literature search was performed using PubMed, Embase, the Cochrane Library, and Web of Science databases. The pooled sensitivity, specificity, diagnostic odds ratio, and area under the summary receiver operating characteristic curve of each category of the JNET and Pit pattern classifications were calculated.RESULTS A total of 19227 colorectal lesions in 31 studies were included. The diagnostic performance of the JNET classification was equivalent to the Pit pattern classification in each corresponding category. The pooled sensitivity, specificity,and area under the curve(AUC) for each category of the JNET classification were as follows: 0.73(95%CI: 0.55-0.85), 0.99(95%CI: 0.97-1.00), and 0.97(95%CI: 0.95-0.98), respectively, for Type 1;0.88(95%CI: 0.78-0.94), 0.72(95%CI: 0.64-0.79), and 0.84(95%CI: 0.81-0.87), respectively, for Type 2 A;0.56(95%CI: 0.47-0.64), 0.91(95%CI: 0.79-0.96), and 0.72(95%CI: 0.68-0.76), respectively, for Type 2 B;0.51(95%CI: 0.42-0.61), 1.00(95%CI: 1.00-1.00), and 0.90(95%CI: 0.87-0.93), respectively, for Type 3.CONCLUSION This meta-analysis suggests that the diagnostic efficacy of the JNET classification may be equivalent to that of the Pit pattern classification. However, due to its simpler and clearer clinical application, the JNET classification should be promoted for the classification of colorectal lesions, and to guide the treatment strategy.
基金National Science and Technology Major Project (Y2019-I-0018-0017)。
文摘Ceramic matrix composites(CMCs) are one of the most promising materials in the field of gas turbines,with superior weight and thermal properties. Its surface morphology is different from the traditional casting airfoil components, which mainly comes from different weaving methods and different braided tow thickness. However, few people have studied the influence of surface morphology of ceramic matrix composites(CMCs) on the development of boundary layer and the resulting flow loss. In this paper, Tex Gen is used to generate different surface morphology structures of ceramic matrix composites(CMCs), and the surface flow characteristics of corresponding CMCs plates are numerically studied. It is found that the slope of the displacement thickness of the woven surface first increases and then decreases in the whole transition interval. Thicker braided tow thickness and denser braiding method will induce earlier flow transition phenomenon and produce greater flow loss;The flow loss on the surface of CMCs plate is mainly composed of the vortex loss in the pit and the boundary layer loss outside the pit, and the boundary layer loss is dominant. The weaving methods has a greater influence on the flow state and flow loss of the boundary layer.
基金supported by Gorgan University of Agricultural Sciences and Natural Resources
文摘In a reserved forest parcel in a virgin eastern Hyrcanian mixed beech forest,80 ha was surveyed to determine the pit and mound topography,canopy gaps and dead trees.The aim was to investigate the spatial patterns and correlation of pit and mound features with canopy gaps.Seventy-five canopy gaps and 61 pit and mound features were identified.The univariate first order nearest neighbor(R_(CE))and bivariate second order test(Ripley’s K)statistic were applied.R_(CE) statistics highlighted a general aggregation pattern for canopy gaps and pits and mounds,while pits and mounds alone were more clumped.Distances between canopy gaps were 130 m average,whereas distances between pit and mound features and dead trees were 60 and 78 m,respectively.Spatial positive correlation of canopy gaps with pits and mounds were observed with all distances.The result of spatial correlations between canopy gaps with pits and mounds confirmed that windthrows cause micro successions in fallen tree ecosystem-scale correlated with gap phase dynamics in the forest community-scale.
文摘Based on the externality theory and the environmental value theory, the hypothesis of charging for waste dumping of open-pit metal mines was put forth. The charging methods were designed according to the characteristics of waste dumping of openpit metal mines, including charging based on the dumping amount of the total waste, multi-charging factors, exceeding standard punishment charging, and so on. The main charging parameter is based on the dumping area rather than the total amount of waste dumping. The charging model of waste dumping of open-pit mines was formulated, and the charging rate was divided into two parts, i.e., the standard charging rate and the differential charging rate. The standard charging rate was derived using the equilibrium dynamic model, whereas the differential one was obtained by establishing the fuzzy synthesized evaluation model.
