Objective:This study was performed to analyze the correlation between pityriasis alba(PA)and the serum 25-hydroxyvitamin D status in children.Methods:The study population comprised 460 patients with PA and 254 age-and...Objective:This study was performed to analyze the correlation between pityriasis alba(PA)and the serum 25-hydroxyvitamin D status in children.Methods:The study population comprised 460 patients with PA and 254 age-and sex-matched healthy controls.The serum level of 25-hydroxyvitamin D was compared between the two groups by studentt test.Results:The serum level of 25-hydroxyvitamin D was significantly lower in patients with PA than in healthy controls(P<0.001).There were statistically significant differences in the serum vitamin D status between the PA group and control group(P<0.001);specifically,patients with PA had a significantly higher frequency of vitamin D deficiency(52.83%vs.24.35%,P=0.001)and lower frequency of vitamin D sufficiency(22.83%vs.37.01%,P<0.001)than controls.PA patients showed significantly lower serum level of vitamin D than controls in deficient and sufficient groups(P=0.005 and 0.027,respectively),and in insufficient group,serum vitamin D level was lower in PA patients than in controls,but it showed no statistical difference(P=0.061).Conclusion:Vitamin D may play a role in the pathogenesis of PA.Further investigations are required to establish the relationship between the severity of PA and the vitamin D status and to evaluate the potential for use of vitamin D in the treatment of PA.展开更多
文摘Objective:This study was performed to analyze the correlation between pityriasis alba(PA)and the serum 25-hydroxyvitamin D status in children.Methods:The study population comprised 460 patients with PA and 254 age-and sex-matched healthy controls.The serum level of 25-hydroxyvitamin D was compared between the two groups by studentt test.Results:The serum level of 25-hydroxyvitamin D was significantly lower in patients with PA than in healthy controls(P<0.001).There were statistically significant differences in the serum vitamin D status between the PA group and control group(P<0.001);specifically,patients with PA had a significantly higher frequency of vitamin D deficiency(52.83%vs.24.35%,P=0.001)and lower frequency of vitamin D sufficiency(22.83%vs.37.01%,P<0.001)than controls.PA patients showed significantly lower serum level of vitamin D than controls in deficient and sufficient groups(P=0.005 and 0.027,respectively),and in insufficient group,serum vitamin D level was lower in PA patients than in controls,but it showed no statistical difference(P=0.061).Conclusion:Vitamin D may play a role in the pathogenesis of PA.Further investigations are required to establish the relationship between the severity of PA and the vitamin D status and to evaluate the potential for use of vitamin D in the treatment of PA.
