AIMS To study the grading of pixu(spleen deficiency)syn- drome and the scientific basis of its relationship with absorption of D-Xylose and BT-PABA. METHODS The present study included 115 cases of chronic su- perficia...AIMS To study the grading of pixu(spleen deficiency)syn- drome and the scientific basis of its relationship with absorption of D-Xylose and BT-PABA. METHODS The present study included 115 cases of chronic su- perficial gastritis,15 cases of chronic atrophic gastritis,19 cases of peptic ulcer and 34 cases of chronic colitis.All of them were diagnosed by endoscopy and biopsies.Chronic gastrointestinal diseases could be categorized into six types,namely,spleen and stomach asthenia syndrome(including asthenia and cold),dishar- mony between liver and stomach,damp and heat of spleen and stomach(bowel)syndrome,spleen-stomach-Yin deficiency,blood stasis and spleen-kidney-Yang deficiency.Grading of these syn- dromes were made with concomitant estimation of d-xylose and BT-PABA tests. RESULTS Patients with chronic gastrointestinal diseases showed diminished urinary level of d-xylosc and that of BT- PABA,as compared with normal,(P<0.05),except those with damp and heat of spleen-bowel syndrome.The excretory rate of d-xylosc was neary normal,while the levels of d-xylose and BT-PABA were lower than those of the normal,(P<0.05-0. 01).In regard to the grading of spleen deficiency and the dishar- mony between liver and stomach syndromes,the excretory rate of D-Xylose decreased gradually(P<0.01 )as the severity of symp- toms increased;in disharmony between liver and stomach syndrome,the excretory rate of BT-PABA also decreased(P<0. 01)as symptoms worsened.These provided scientific proofs for appraisal of the pathophysiology of these syndromes. CONCLUSIONS Changes of d-xylose can reflect the specifici- ty of pixu syndrome whereas changes of BT-PABA reflect the specificity of disharmony between liver and stomach syndrome.展开更多
AIMS The paper studies the relationship between spleen deficiency substance,spleen deficiency and gastric cancer. METHODS We adopted the IBAS 2000 image analysis system,501B SEM with 9100/60 energy chromatic dispersin...AIMS The paper studies the relationship between spleen deficiency substance,spleen deficiency and gastric cancer. METHODS We adopted the IBAS 2000 image analysis system,501B SEM with 9100/60 energy chromatic dispersing X-ray analysis instrument technique,histologic chemistry and radio-immunity means to assay the ultramicro structure,in- testinal rnetaplasia subtypes,cAMP,DNA,trace element series and their oxides of the patients' gastric mucosa. RESULTS The incidence rates of gastric cancer,incom- plete colonic intestinal metaplasia and“background lesion”of spleen deficiency with Qi stagnation patients are remarkably higher than those of spleen Qi deficiency patients(P<0.05- 0.001 ).The levels of gastric mucosa cAMP,Zn,Cu,ZnO and CuO decreased from complete to incomplete intestinal meta- plasia and from small to colonic intestinal metaplasia,while DNA increased in the above sequence(P<0.05-0.001 ).The lev- els of DNA,cAMP,Zn,Cu,ZnO and CuO in gastric mucosa of incomplete colonic intestinal metaplasia tissue are not remark- ably different from those in gastric cancer tissue. CONCLUSION Gastric diseases of spleen dificiency with Qi stagnation has the tendency of cancerization; There is a close relationship between the incidence of incomplete colonic intestinal metaplasia and gastric cancer.展开更多
文摘AIMS To study the grading of pixu(spleen deficiency)syn- drome and the scientific basis of its relationship with absorption of D-Xylose and BT-PABA. METHODS The present study included 115 cases of chronic su- perficial gastritis,15 cases of chronic atrophic gastritis,19 cases of peptic ulcer and 34 cases of chronic colitis.All of them were diagnosed by endoscopy and biopsies.Chronic gastrointestinal diseases could be categorized into six types,namely,spleen and stomach asthenia syndrome(including asthenia and cold),dishar- mony between liver and stomach,damp and heat of spleen and stomach(bowel)syndrome,spleen-stomach-Yin deficiency,blood stasis and spleen-kidney-Yang deficiency.Grading of these syn- dromes were made with concomitant estimation of d-xylose and BT-PABA tests. RESULTS Patients with chronic gastrointestinal diseases showed diminished urinary level of d-xylosc and that of BT- PABA,as compared with normal,(P<0.05),except those with damp and heat of spleen-bowel syndrome.The excretory rate of d-xylosc was neary normal,while the levels of d-xylose and BT-PABA were lower than those of the normal,(P<0.05-0. 01).In regard to the grading of spleen deficiency and the dishar- mony between liver and stomach syndromes,the excretory rate of D-Xylose decreased gradually(P<0.01 )as the severity of symp- toms increased;in disharmony between liver and stomach syndrome,the excretory rate of BT-PABA also decreased(P<0. 01)as symptoms worsened.These provided scientific proofs for appraisal of the pathophysiology of these syndromes. CONCLUSIONS Changes of d-xylose can reflect the specifici- ty of pixu syndrome whereas changes of BT-PABA reflect the specificity of disharmony between liver and stomach syndrome.
文摘AIMS The paper studies the relationship between spleen deficiency substance,spleen deficiency and gastric cancer. METHODS We adopted the IBAS 2000 image analysis system,501B SEM with 9100/60 energy chromatic dispersing X-ray analysis instrument technique,histologic chemistry and radio-immunity means to assay the ultramicro structure,in- testinal rnetaplasia subtypes,cAMP,DNA,trace element series and their oxides of the patients' gastric mucosa. RESULTS The incidence rates of gastric cancer,incom- plete colonic intestinal metaplasia and“background lesion”of spleen deficiency with Qi stagnation patients are remarkably higher than those of spleen Qi deficiency patients(P<0.05- 0.001 ).The levels of gastric mucosa cAMP,Zn,Cu,ZnO and CuO decreased from complete to incomplete intestinal meta- plasia and from small to colonic intestinal metaplasia,while DNA increased in the above sequence(P<0.05-0.001 ).The lev- els of DNA,cAMP,Zn,Cu,ZnO and CuO in gastric mucosa of incomplete colonic intestinal metaplasia tissue are not remark- ably different from those in gastric cancer tissue. CONCLUSION Gastric diseases of spleen dificiency with Qi stagnation has the tendency of cancerization; There is a close relationship between the incidence of incomplete colonic intestinal metaplasia and gastric cancer.
