The problem of two-dimensional direction of arrival(2D-DOA)estimation for uniform planar arrays(UPAs)is investigated by employing the reduced-dimensional(RD)polynomial root finding technique and 2D multiple signal cla...The problem of two-dimensional direction of arrival(2D-DOA)estimation for uniform planar arrays(UPAs)is investigated by employing the reduced-dimensional(RD)polynomial root finding technique and 2D multiple signal classification(2D-MUSIC)algorithm.Specifically,based on the relationship between the noise subspace and steering vectors,we first construct 2D root polynomial for 2D-DOA estimates and then prove that the 2D polynomial function has infinitely many solutions.In particular,we propose a computationally efficient algorithm,termed RD-ROOT-MUSIC algorithm,to obtain the true solutions corresponding to targets by RD technique,where the 2D root-finding problem is substituted by two one-dimensional(1D)root-finding operations.Finally,accurate 2DDOA estimates can be obtained by a sample pairing approach.In addition,numerical simulation results are given to corroborate the advantages of the proposed algorithm.展开更多
Sparse arrays of telescopes have a limited (u, v)-plane coverage. In this paper, an optimization method for designing planar arrays of an aperture synthesis telescope is proposed that is based on distributed genetic a...Sparse arrays of telescopes have a limited (u, v)-plane coverage. In this paper, an optimization method for designing planar arrays of an aperture synthesis telescope is proposed that is based on distributed genetic algorithm. This distributed genetic algorithm is implemented on a network of workstations using community communication model. Such an aperture synthesis system performs with imperfection of (u, v) components caused by deviations and(or) some missing baselines. With the maximum (u, v)-plane coverage of this rotation-optimized array, the image of the source reconstructed by inverse Fourier transform is satisfactory.展开更多
A novel low-cost 4-element planar array antenna directly fed by a coaxial cable for Ultra-WideBand(UWB) application is presented. The proposed antenna consists of 2×2 bowtie elements and a simple 1:4 power divide...A novel low-cost 4-element planar array antenna directly fed by a coaxial cable for Ultra-WideBand(UWB) application is presented. The proposed antenna consists of 2×2 bowtie elements and a simple 1:4 power divider feeding network. Compared to the basic bowtie element, the impedance bandwidth of the array antenna has a significant improvement that the low cut-off frequency is extended from 6 GHz of the bowtie element to 2 GHz. The measured results show that the proposed antenna has a large bandwidth of 2 GHz to 11 GHz for Voltage Standing Wave Ratio(VSWR)<2, and exhibits a bidirectional radiation pattern and a modest gain across the operating band and a peak gain of about 9 dBi at 11 GHz.展开更多
The resistance and inductance of a wire array during an implosion are very important parameters of interest to:researchers. A variety of inductances and resistances directly affect the kinetic energy and resistance h...The resistance and inductance of a wire array during an implosion are very important parameters of interest to:researchers. A variety of inductances and resistances directly affect the kinetic energy and resistance heat energy coupled from a pulsed-power generator. In this paper, the inductance and resistance of a planar wire array during the Z-pinch process are analyzed. The inductance is calculated from the data obtained by a time-resolved soft X-ray framed camera, while the resistance is calculated through the voltage and the current of the wire array load combined with the variety of the inductance. The results show that the resistance of the load increases with the development of the implosion, and reaches its maximum at 0.29 ± 0.16Ω near the pinched time.展开更多
Two dynamics modes, named short ablation mode and long ablation mode, are observed in implosion experiments of planar wire array Z pinch on 'QiangGuang-I' facility utilizing an optical streak camera. The long ablati...Two dynamics modes, named short ablation mode and long ablation mode, are observed in implosion experiments of planar wire array Z pinch on 'QiangGuang-I' facility utilizing an optical streak camera. The long ablation mode has a lagged trajectory compared with the short ablation mode. For shot 10035 in a short ablation mode, the initial time of K-shell radiation is consistent with the interaction time for ablation plasma arriving at the centre of wire array, while for shot 10038 in long ablation mode, the initial time of K-shell radiation is about 10 ns earlier. In the two modes, the partial ablation plasma could traverse the wire array plane and then collide in the centre to form a dense plasma column with a diameter of 2.2 mm for shot 10035 and 1.5 mm for shot 10038.展开更多
The concept of difference and sum co-array(DSCA)has become a new design idea for planar sparse arrays.Inspired by the shifting invariance property of DSCA,a specific configuration named here as the improved L-shaped a...The concept of difference and sum co-array(DSCA)has become a new design idea for planar sparse arrays.Inspired by the shifting invariance property of DSCA,a specific configuration named here as the improved L-shaped array is proposed.Compared to other traditional 2D sparse array configurations such as 2D nested arrays and hourglass arrays,the proposed configuration has larger central consecutive ranges in its DSCA,thus increasing the DOF.At the same time,the mutual coupling effect is also reduced due to the enlarged spacing between the adjacent sensors.Simulations further demonstrate the superiority of the proposed arrays in terms of detection performance and estimation accuracy.展开更多
The concept of difference and sum(diff-sum)coarray has attracted a lot of attentions in the estimation of direction-of-arrival(DOA)for the past few years,due to its high degrees-of-freedom(DOFs).A vectorized conjugate...The concept of difference and sum(diff-sum)coarray has attracted a lot of attentions in the estimation of direction-of-arrival(DOA)for the past few years,due to its high degrees-of-freedom(DOFs).A vectorized conjugate augmented MUSIC(VCA-MUSIC)algorithm is applied to generate an equivalent signal model which contains the virtual sensor positions of both the difference and sum of the physical sensors in the two-dimensional(2D)arrays,by utilizing both the spatial and temporal information.Besides,an augmented 2D coprime array configuration is presented with the basis on the concept of difference and sum coarray.By compressing the inter-element spacing of one subarray and introducing the proper separation between the two subarrays of 2D coprime array,the redundancy between the difference coarray and the sum one can be reduced so that more virtual sensors in both coarrays can make contributions to the DOFs.As a result,a much larger consecutive area in the diff-sum coarray can be achieved,which can significantly increase the DOFs.Numerical simulations verify the superiority of the proposed array configuration.展开更多
In this paper,we investigate the end-to-end performance of intelligent reflecting surface(IRS)-assisted wireless communication systems.We consider a system in which an IRS is deployed on a uniform planar array(UPA)con...In this paper,we investigate the end-to-end performance of intelligent reflecting surface(IRS)-assisted wireless communication systems.We consider a system in which an IRS is deployed on a uniform planar array(UPA)configuration,including a large number of reflecting elements,where the transmitters and receivers are only equipped with a single antenna.Our objective is to analytically obtain the achievable ergodic rate,outage probability,and bit error rate(BER)of the system.Furthermore,to maximize the system’s signal-to-noise ratio(SNR),we design the phase shift of each reflecting element and derive the optimal reflection phase of the IRS based on the channel state information(CSI).We also derive the exact expression of the SNR probability density function(p.d.f.)and show that it follows a non-central Chi-square distribution.Using the p.d.f.,we then derive the theoretical results of the achievable rate,outage probability,and BER.The accuracy of the obtained theoretical results is also verified through numerical simulation.Itwas shown that the achievable rate,outage probability,and BER could be improved by increasing the number of reflecting elements and choosing an appropriate SNR regime.Furthermore,we also find that the IRS-assisted communication system achieves better performance than the existing end-to-end wireless communication.展开更多
Naturally suited array geometry for 360° coverage is the uniform circular array (UCA). A comparison of two types of uniform circular array configurations is presented in this paper. Due to its symmetrical...Naturally suited array geometry for 360° coverage is the uniform circular array (UCA). A comparison of two types of uniform circular array configurations is presented in this paper. Due to its symmetrical geometry UCA is always targeted which results in minimal change inside lobe levels and beam width when scanned by a phased array antenna. Particle Swarm Optimization and Cuckoo algorithm are used for the calculation of complex weights of the array elements. Comparisons are drawn in the context of adaptive beam forming capabilities. Obtained results suggest that planar uniform circular array (9:10) using Cuckoo algorithm, has better beam forming properties with also reduced side lobe levels when compared to other geometry.展开更多
Purpose-The purpose of this paper is to propose radiating system by avoiding electromagnetic interference in unwanted directions and to radiate the energy in the required direction with an optimization technique.Desig...Purpose-The purpose of this paper is to propose radiating system by avoiding electromagnetic interference in unwanted directions and to radiate the energy in the required direction with an optimization technique.Design/methodology/approach-Practically,multiple,incompatible variables require concurrent boost on a synthesis of systematic antenna assemblage.The authors have worked out the main statistic penalty function to ensure all the restrictions.Here,MBPSO(Modified Binary Particle Swarm Optimization)is developed and introduced thin planar synthesis restriction.The sigmoid function is used to update the particle position.Different analytical demonstrations have been carried out,and the exhibited methods are predominant than the algorithms.Findings-A 20310 planar antenna array is synthesized using modified BPSO.The authors have suppressed the PSLL in two principal planes and as well as in the entire f plane.Numerical results state that MBPSO outperforms the other binary BPSO,BCSO,ACO,RGA,GAoptimization techniques.MBPSO achieved a51.84 dB PSLL level,whereas BPSO achieved48.57 dB with the same 50%thinning.Originality/value-Planar array antenna formation is one of the most complex syntheses because the array gets filled with more antenna elements.The machine-like complication and implementation of such an antenna arrangement with a broad opening would be expensive.It is not easy to control the required radiation patterns shape by using a uniform feeding network.To get better flexibility for sustaining the sidelobe levelheaded along with consistent amplitude distribution.So as far as prominence has been given to the evolutionary algorithm,find an ideal solution for objective array combinational problems.展开更多
A large planar microphone array, which consists of 111 microphones, was successfully developed. The positions of 111 microphones in the array were determined by a random optimization procedure for the largest possible...A large planar microphone array, which consists of 111 microphones, was successfully developed. The positions of 111 microphones in the array were determined by a random optimization procedure for the largest possible amplification and dynamic range. The beam pattern of planar array was obtained by numerical calculation. This planar array was applied to measure a two-dimensional mapping of the sound sources on landing aircraft. It is shown that important airframe noise sources can be identified. The spectra and directivity of any interested noise source can also be obtained by this measurement.展开更多
To achieve a dopamine (DA) response with high sensitivity and high signal-to-noise ratio (S/N) with a patch-clamp system, polypyrrole/graphene (PPy/GR) nanocomposites were steadily electrodeposited by an electro...To achieve a dopamine (DA) response with high sensitivity and high signal-to-noise ratio (S/N) with a patch-clamp system, polypyrrole/graphene (PPy/GR) nanocomposites were steadily electrodeposited by an electrochemical method on a planar mi- croelectrode array (pMEA) fabricated by a standard micromachining process. The electrodeposition process was carried out by chronopotentimetry measurement scanning from 0.1 to 0.8 C/cm2 at the current of 2 mA; 0.5 C/cm2 was found to be optimal. The pMEA modified by PPy/GR at the 0.5 C/cm2 exhibits remarkable properties; for instance, the standard deviation (SD) de- creases from 8.4614×10-al to 5.62×10 11 A, reduced by 33.52%, and the sensitivity increases from 2566.88 to 76114.65 gAmMcm2 , 29.65 times higher than the bare Pt (platinum). A good linear relationship between the current and DA concentra- tion in the range of 0.30 to 61.71 grn was obtained, with a correlation coefficient of 0.997. The sensor is meaningful for neuro- science research and the treatment of neurological diseases.展开更多
Objective The well-established planar multi-electrode array recording technique was used to investigate neural circuits and temporal plasticity in the hindlimb representation of the rat primary somatosensory cortex (...Objective The well-established planar multi-electrode array recording technique was used to investigate neural circuits and temporal plasticity in the hindlimb representation of the rat primary somatosensory cortex (S1 area) . Methods Freshly dissociated acute brain slices of rats were subject to constant perfusion with oxygenated artificial cerebrospinal fluid (95% O2 and 5% CO2) , and were mounted on a Med64 probe (64 electrodes, 8×8 array) for simultaneous multi-site electrophysiological recordings. Current sources and sinks across all the 64 electrodes were transformed into two-dimensional current source density images by bilinear interpolation at each point of the 64 electrodes. Results The local intracortical connection, which is involved in mediation of downward information flow across layers II-VI, was identified by electrical stimulation (ES) at layers II-III. The thalamocortical connection, which is mainly involved in mediation of upward information flow across layers II-IV, was also characterized by ES at layer IV. The thalamocortical afferent projections were likely to make more synaptic contacts with S1 neurons than the intracortical connections did. Moreover, the S1 area was shown to be more easily activated and more intensively innervated by the thalamocortical afferent projections than by the intracortical connections. Finally, bursting conditioning stimulus (CS) applied within layer IV of the S1 area could success-fully induce long-term potentiation (LTP) in 5 of the 6 slices (83.3%) , while the same CS application at layers II-III induced no LTP in any of the 6 tested slices. Conclusion The rat hindlimb representation of S1 area is likely to have at least 2 patterns of neural circuits on brain slices: one is the intracortical circuit (ICC) formed by interlaminar connections from layers II-III, and the other is the thalamocortical circuit (TCC) mediated by afferent connections from layer IV. Besides, ICC of the S1 area is spatially limited, with less plasticity, while TCC is spatially extensive and exhibits a better plasticity in response to somatosensory afferent stimulation. The present data provide a useful experimental model for further studying microcircuit properties in S1 cortex at the network level in vitro.展开更多
Controlling the vapor-deposited nanoribbons to grow along a consistent orientation will enable the desired in situ integration of functional devices,representing a major technological advance compared to post-growth p...Controlling the vapor-deposited nanoribbons to grow along a consistent orientation will enable the desired in situ integration of functional devices,representing a major technological advance compared to post-growth processing strategies.In this work,ntype F_(16)CuPc molecules are self-assembled into horizontally-oriented nanoribbons with a consistent growth axis after creating periodic hydrophobic nanogrooves on a sapphire surface.Consequently,electrodes are deposited directly on the growth substrate to enable in situ fabrication of photodetectors.Depending on the deposited electrodes,these horizontally-oriented nanoribbons are connected to form a monolithic photodetector with a large sensing area or an on-chip array of photodetectors with multiple detector units.This in situ integration strategy avoids potential structural damage and contamination from impurities associated with post-growth processing steps.Therefore,the vapor-deposited nanoribbons can retain their high quality during the device manufacturing process,which contributes to performance improvement.As a result,the in-situ integrated F_(16)CuPc photodetectors exhibit a sensitive response in the ultraviolet-visible-near-infrared(UV-vis-NIR)region.The response time is on the order of tens of milliseconds,the fastest record ever for the F_(16)CuPc-based photodetectors.Furthermore,statistics from an array of 6×6 photodetectors show little variation in their sensitivity and response time,and hence this in situ fabrication scheme will contribute to the implementation of on-chip integrated photodetectors with consistent performance based on bottom-up nanoribbons.Overall,this self-oriented growth provides a versatile option to achieve desired in-situ integrated functional devices based on bottom-up nanoribbons.展开更多
基金supported by the National Natural Science Foundation of China(Nos.61631020,61971218,61601167,61371169)。
文摘The problem of two-dimensional direction of arrival(2D-DOA)estimation for uniform planar arrays(UPAs)is investigated by employing the reduced-dimensional(RD)polynomial root finding technique and 2D multiple signal classification(2D-MUSIC)algorithm.Specifically,based on the relationship between the noise subspace and steering vectors,we first construct 2D root polynomial for 2D-DOA estimates and then prove that the 2D polynomial function has infinitely many solutions.In particular,we propose a computationally efficient algorithm,termed RD-ROOT-MUSIC algorithm,to obtain the true solutions corresponding to targets by RD technique,where the 2D root-finding problem is substituted by two one-dimensional(1D)root-finding operations.Finally,accurate 2DDOA estimates can be obtained by a sample pairing approach.In addition,numerical simulation results are given to corroborate the advantages of the proposed algorithm.
基金This project was supported by the High Technology Research and Development Programme of China (2002AA111040).
文摘Sparse arrays of telescopes have a limited (u, v)-plane coverage. In this paper, an optimization method for designing planar arrays of an aperture synthesis telescope is proposed that is based on distributed genetic algorithm. This distributed genetic algorithm is implemented on a network of workstations using community communication model. Such an aperture synthesis system performs with imperfection of (u, v) components caused by deviations and(or) some missing baselines. With the maximum (u, v)-plane coverage of this rotation-optimized array, the image of the source reconstructed by inverse Fourier transform is satisfactory.
基金Supported by the National High Technology Research and Development Program(No.2012AA121901)
文摘A novel low-cost 4-element planar array antenna directly fed by a coaxial cable for Ultra-WideBand(UWB) application is presented. The proposed antenna consists of 2×2 bowtie elements and a simple 1:4 power divider feeding network. Compared to the basic bowtie element, the impedance bandwidth of the array antenna has a significant improvement that the low cut-off frequency is extended from 6 GHz of the bowtie element to 2 GHz. The measured results show that the proposed antenna has a large bandwidth of 2 GHz to 11 GHz for Voltage Standing Wave Ratio(VSWR)<2, and exhibits a bidirectional radiation pattern and a modest gain across the operating band and a peak gain of about 9 dBi at 11 GHz.
基金supported by National Natural Science Fundation of China(No.10905047)
文摘The resistance and inductance of a wire array during an implosion are very important parameters of interest to:researchers. A variety of inductances and resistances directly affect the kinetic energy and resistance heat energy coupled from a pulsed-power generator. In this paper, the inductance and resistance of a planar wire array during the Z-pinch process are analyzed. The inductance is calculated from the data obtained by a time-resolved soft X-ray framed camera, while the resistance is calculated through the voltage and the current of the wire array load combined with the variety of the inductance. The results show that the resistance of the load increases with the development of the implosion, and reaches its maximum at 0.29 ± 0.16Ω near the pinched time.
文摘Two dynamics modes, named short ablation mode and long ablation mode, are observed in implosion experiments of planar wire array Z pinch on 'QiangGuang-I' facility utilizing an optical streak camera. The long ablation mode has a lagged trajectory compared with the short ablation mode. For shot 10035 in a short ablation mode, the initial time of K-shell radiation is consistent with the interaction time for ablation plasma arriving at the centre of wire array, while for shot 10038 in long ablation mode, the initial time of K-shell radiation is about 10 ns earlier. In the two modes, the partial ablation plasma could traverse the wire array plane and then collide in the centre to form a dense plasma column with a diameter of 2.2 mm for shot 10035 and 1.5 mm for shot 10038.
基金Supported by the National Natural Science Foundation of China(61801024)。
文摘The concept of difference and sum co-array(DSCA)has become a new design idea for planar sparse arrays.Inspired by the shifting invariance property of DSCA,a specific configuration named here as the improved L-shaped array is proposed.Compared to other traditional 2D sparse array configurations such as 2D nested arrays and hourglass arrays,the proposed configuration has larger central consecutive ranges in its DSCA,thus increasing the DOF.At the same time,the mutual coupling effect is also reduced due to the enlarged spacing between the adjacent sensors.Simulations further demonstrate the superiority of the proposed arrays in terms of detection performance and estimation accuracy.
基金Supported by the National Natural Science Foundation of China(61801024)。
文摘The concept of difference and sum(diff-sum)coarray has attracted a lot of attentions in the estimation of direction-of-arrival(DOA)for the past few years,due to its high degrees-of-freedom(DOFs).A vectorized conjugate augmented MUSIC(VCA-MUSIC)algorithm is applied to generate an equivalent signal model which contains the virtual sensor positions of both the difference and sum of the physical sensors in the two-dimensional(2D)arrays,by utilizing both the spatial and temporal information.Besides,an augmented 2D coprime array configuration is presented with the basis on the concept of difference and sum coarray.By compressing the inter-element spacing of one subarray and introducing the proper separation between the two subarrays of 2D coprime array,the redundancy between the difference coarray and the sum one can be reduced so that more virtual sensors in both coarrays can make contributions to the DOFs.As a result,a much larger consecutive area in the diff-sum coarray can be achieved,which can significantly increase the DOFs.Numerical simulations verify the superiority of the proposed array configuration.
基金supported in part by the Joint Research Fund for Guangzhou University and Hong Kong University of Science and Technology under Grant No.YH202203the Guangzhou Basic Research Program Municipal School(College)Joint Funding Project,the Research Project of Guizhou University for Talent Introduction under Grant No.[2020]61+7 种基金the Cultivation Project of Guizhou University under Grant No.[2019]56the Open Fund of Key Laboratory of Advanced Manufacturing Technology,Ministry of Education under Grant No.GZUAMT2021KF[01]the National Natural Science Foundation of China under Grant Nos.51978089 and 62171119the Key R&D Plan of Sichuan Science and Technology Department under Grant No.22ZDYF2726the Chengdu Normal University Scientific Research and Innovation Team under Grant Nos.CSCXTD2020B09,ZZBS201907,CS21ZC01the Open Project of Intelligent Manufacturing Industry Technology Research Institute under Grant No.ZNZZ2208the National Key Research and Development Program of China under Grant No.2020YFB1807201Key research and development plan of Jiangsu Province under Grant No.BE2021013-3.
文摘In this paper,we investigate the end-to-end performance of intelligent reflecting surface(IRS)-assisted wireless communication systems.We consider a system in which an IRS is deployed on a uniform planar array(UPA)configuration,including a large number of reflecting elements,where the transmitters and receivers are only equipped with a single antenna.Our objective is to analytically obtain the achievable ergodic rate,outage probability,and bit error rate(BER)of the system.Furthermore,to maximize the system’s signal-to-noise ratio(SNR),we design the phase shift of each reflecting element and derive the optimal reflection phase of the IRS based on the channel state information(CSI).We also derive the exact expression of the SNR probability density function(p.d.f.)and show that it follows a non-central Chi-square distribution.Using the p.d.f.,we then derive the theoretical results of the achievable rate,outage probability,and BER.The accuracy of the obtained theoretical results is also verified through numerical simulation.Itwas shown that the achievable rate,outage probability,and BER could be improved by increasing the number of reflecting elements and choosing an appropriate SNR regime.Furthermore,we also find that the IRS-assisted communication system achieves better performance than the existing end-to-end wireless communication.
文摘Naturally suited array geometry for 360° coverage is the uniform circular array (UCA). A comparison of two types of uniform circular array configurations is presented in this paper. Due to its symmetrical geometry UCA is always targeted which results in minimal change inside lobe levels and beam width when scanned by a phased array antenna. Particle Swarm Optimization and Cuckoo algorithm are used for the calculation of complex weights of the array elements. Comparisons are drawn in the context of adaptive beam forming capabilities. Obtained results suggest that planar uniform circular array (9:10) using Cuckoo algorithm, has better beam forming properties with also reduced side lobe levels when compared to other geometry.
文摘Purpose-The purpose of this paper is to propose radiating system by avoiding electromagnetic interference in unwanted directions and to radiate the energy in the required direction with an optimization technique.Design/methodology/approach-Practically,multiple,incompatible variables require concurrent boost on a synthesis of systematic antenna assemblage.The authors have worked out the main statistic penalty function to ensure all the restrictions.Here,MBPSO(Modified Binary Particle Swarm Optimization)is developed and introduced thin planar synthesis restriction.The sigmoid function is used to update the particle position.Different analytical demonstrations have been carried out,and the exhibited methods are predominant than the algorithms.Findings-A 20310 planar antenna array is synthesized using modified BPSO.The authors have suppressed the PSLL in two principal planes and as well as in the entire f plane.Numerical results state that MBPSO outperforms the other binary BPSO,BCSO,ACO,RGA,GAoptimization techniques.MBPSO achieved a51.84 dB PSLL level,whereas BPSO achieved48.57 dB with the same 50%thinning.Originality/value-Planar array antenna formation is one of the most complex syntheses because the array gets filled with more antenna elements.The machine-like complication and implementation of such an antenna arrangement with a broad opening would be expensive.It is not easy to control the required radiation patterns shape by using a uniform feeding network.To get better flexibility for sustaining the sidelobe levelheaded along with consistent amplitude distribution.So as far as prominence has been given to the evolutionary algorithm,find an ideal solution for objective array combinational problems.
基金the Bundesministerium fur Bildung und Forschung (BMBF) of Germany.
文摘A large planar microphone array, which consists of 111 microphones, was successfully developed. The positions of 111 microphones in the array were determined by a random optimization procedure for the largest possible amplification and dynamic range. The beam pattern of planar array was obtained by numerical calculation. This planar array was applied to measure a two-dimensional mapping of the sound sources on landing aircraft. It is shown that important airframe noise sources can be identified. The spectra and directivity of any interested noise source can also be obtained by this measurement.
基金supported by the National Natural Science Foundation of China(Grant Nos.61125105,61101048,61271147,and 61002037)National Basic Research Program of China("973" Program)(Grant Nos.2011CB933202,2014CB744605)
文摘To achieve a dopamine (DA) response with high sensitivity and high signal-to-noise ratio (S/N) with a patch-clamp system, polypyrrole/graphene (PPy/GR) nanocomposites were steadily electrodeposited by an electrochemical method on a planar mi- croelectrode array (pMEA) fabricated by a standard micromachining process. The electrodeposition process was carried out by chronopotentimetry measurement scanning from 0.1 to 0.8 C/cm2 at the current of 2 mA; 0.5 C/cm2 was found to be optimal. The pMEA modified by PPy/GR at the 0.5 C/cm2 exhibits remarkable properties; for instance, the standard deviation (SD) de- creases from 8.4614×10-al to 5.62×10 11 A, reduced by 33.52%, and the sensitivity increases from 2566.88 to 76114.65 gAmMcm2 , 29.65 times higher than the bare Pt (platinum). A good linear relationship between the current and DA concentra- tion in the range of 0.30 to 61.71 grn was obtained, with a correlation coefficient of 0.997. The sensor is meaningful for neuro- science research and the treatment of neurological diseases.
基金supported by the National Basic Research Development Program(973)of China(No.2006CB500800)National Innovation Team Program of Ministry of Education(No.IRT0560)National Natural Science Foundation of China(No.30670692 and 30770668)
文摘Objective The well-established planar multi-electrode array recording technique was used to investigate neural circuits and temporal plasticity in the hindlimb representation of the rat primary somatosensory cortex (S1 area) . Methods Freshly dissociated acute brain slices of rats were subject to constant perfusion with oxygenated artificial cerebrospinal fluid (95% O2 and 5% CO2) , and were mounted on a Med64 probe (64 electrodes, 8×8 array) for simultaneous multi-site electrophysiological recordings. Current sources and sinks across all the 64 electrodes were transformed into two-dimensional current source density images by bilinear interpolation at each point of the 64 electrodes. Results The local intracortical connection, which is involved in mediation of downward information flow across layers II-VI, was identified by electrical stimulation (ES) at layers II-III. The thalamocortical connection, which is mainly involved in mediation of upward information flow across layers II-IV, was also characterized by ES at layer IV. The thalamocortical afferent projections were likely to make more synaptic contacts with S1 neurons than the intracortical connections did. Moreover, the S1 area was shown to be more easily activated and more intensively innervated by the thalamocortical afferent projections than by the intracortical connections. Finally, bursting conditioning stimulus (CS) applied within layer IV of the S1 area could success-fully induce long-term potentiation (LTP) in 5 of the 6 slices (83.3%) , while the same CS application at layers II-III induced no LTP in any of the 6 tested slices. Conclusion The rat hindlimb representation of S1 area is likely to have at least 2 patterns of neural circuits on brain slices: one is the intracortical circuit (ICC) formed by interlaminar connections from layers II-III, and the other is the thalamocortical circuit (TCC) mediated by afferent connections from layer IV. Besides, ICC of the S1 area is spatially limited, with less plasticity, while TCC is spatially extensive and exhibits a better plasticity in response to somatosensory afferent stimulation. The present data provide a useful experimental model for further studying microcircuit properties in S1 cortex at the network level in vitro.
基金The authors acknowledge the financial support by the 2019QN01C290Guangdong Basic and Applied Basic Research Foundation(No.2021A1515012235)+1 种基金the Outstanding Young Scholar at South China Normal University,Science and Technology Program of Guangzhou(No.2019050001)Guangdong Provincial Key Laboratory of Optical Information Materials and Technology(No.2017B030301007).
文摘Controlling the vapor-deposited nanoribbons to grow along a consistent orientation will enable the desired in situ integration of functional devices,representing a major technological advance compared to post-growth processing strategies.In this work,ntype F_(16)CuPc molecules are self-assembled into horizontally-oriented nanoribbons with a consistent growth axis after creating periodic hydrophobic nanogrooves on a sapphire surface.Consequently,electrodes are deposited directly on the growth substrate to enable in situ fabrication of photodetectors.Depending on the deposited electrodes,these horizontally-oriented nanoribbons are connected to form a monolithic photodetector with a large sensing area or an on-chip array of photodetectors with multiple detector units.This in situ integration strategy avoids potential structural damage and contamination from impurities associated with post-growth processing steps.Therefore,the vapor-deposited nanoribbons can retain their high quality during the device manufacturing process,which contributes to performance improvement.As a result,the in-situ integrated F_(16)CuPc photodetectors exhibit a sensitive response in the ultraviolet-visible-near-infrared(UV-vis-NIR)region.The response time is on the order of tens of milliseconds,the fastest record ever for the F_(16)CuPc-based photodetectors.Furthermore,statistics from an array of 6×6 photodetectors show little variation in their sensitivity and response time,and hence this in situ fabrication scheme will contribute to the implementation of on-chip integrated photodetectors with consistent performance based on bottom-up nanoribbons.Overall,this self-oriented growth provides a versatile option to achieve desired in-situ integrated functional devices based on bottom-up nanoribbons.