Keyhole surgeries become mcreasingly important in clinical daily routine as they help minimizing the damage of a patient's healthy tissue.The planning of keyhole surgeries is based on medical imaging and an import...Keyhole surgeries become mcreasingly important in clinical daily routine as they help minimizing the damage of a patient's healthy tissue.The planning of keyhole surgeries is based on medical imaging and an important factor that influences the surgeries*success.Due to the image reconstruction process,medical image data contains uncertainty that exacerbates the planning of a keyhole surgery.In this paper we present a visual workflow that helps clinicians to examine and compare different surgery paths as well as visualizing the patientsJ affected tissue.The analysis is based on the concept of hierarchical image semantics,that segment the underlying image data with respect to the input images'uncertainty and the users understanding of tissue composition.Users can define arbitrary surgery paths that they need to investigate further.The defined paths can be queried by a rating function to identify paths that fulfill user-defined properties.The workflow allows a visual inspection of the affected tissues and its substructures.Therefore,the workflow includes a linked view system indicating the three-dimensional location of selected surgery paths as well as how these paths affect the patients tissue.To show the effectiveness of the presented approach,we applied it to the planning of a keyhole surgery of a brain tumor removal and a kneecap surgery.展开更多
Background:Myxofibrosarcoma(MFS),especially radiation-Induced MFS(RIMFS)in the head and neck,is an extremely rare malignant fibroblastic tumor.The diagnosis and treatment of MFS remain great challenges.In the present ...Background:Myxofibrosarcoma(MFS),especially radiation-Induced MFS(RIMFS)in the head and neck,is an extremely rare malignant fibroblastic tumor.The diagnosis and treatment of MFS remain great challenges.In the present study,we presented one case of RIMFS.Combined with previous literature,the clinical features,essentials of diagnosis,and treatment modalities of MFS in the head and neck were reviewed to better understand this rare entity.Case presentation:We reported a case of RIMFS under the left occipital scalp in a 20-year-old girl with a history of medulloblastoma surgery and radiotherapy in 2006.A total tumor resection was performed with preservation of the overlying scalp the underlying bone,and no adjuvant therapy was administered after the first operation.The postoperative pathological diagnosis was high-grade MFS.The tumor relapsed 6 months later,and then,a planned extensive resection with negative surgical margins was carried out,followed by radiotherapy.No relapse occurred in a 12-month postoperative follow-up.Conclusions:Planned gross total resection(GTR)with negative margins is the reasonable choice and footstone of other treatments for MFS.Ill-defined infiltrated borders and the complicated structures make it a great trouble to achieve total resection of MFS in the head and neck,so adjuvant radiotherapy and chemotherapy seem more necessary for these lesions.展开更多
基金This research was funded by the German Research Foundation(DFG)within the IRTG 2057"Physical Modeling for Virtual Manufacturing Systems and Processes”.
文摘Keyhole surgeries become mcreasingly important in clinical daily routine as they help minimizing the damage of a patient's healthy tissue.The planning of keyhole surgeries is based on medical imaging and an important factor that influences the surgeries*success.Due to the image reconstruction process,medical image data contains uncertainty that exacerbates the planning of a keyhole surgery.In this paper we present a visual workflow that helps clinicians to examine and compare different surgery paths as well as visualizing the patientsJ affected tissue.The analysis is based on the concept of hierarchical image semantics,that segment the underlying image data with respect to the input images'uncertainty and the users understanding of tissue composition.Users can define arbitrary surgery paths that they need to investigate further.The defined paths can be queried by a rating function to identify paths that fulfill user-defined properties.The workflow allows a visual inspection of the affected tissues and its substructures.Therefore,the workflow includes a linked view system indicating the three-dimensional location of selected surgery paths as well as how these paths affect the patients tissue.To show the effectiveness of the presented approach,we applied it to the planning of a keyhole surgery of a brain tumor removal and a kneecap surgery.
文摘Background:Myxofibrosarcoma(MFS),especially radiation-Induced MFS(RIMFS)in the head and neck,is an extremely rare malignant fibroblastic tumor.The diagnosis and treatment of MFS remain great challenges.In the present study,we presented one case of RIMFS.Combined with previous literature,the clinical features,essentials of diagnosis,and treatment modalities of MFS in the head and neck were reviewed to better understand this rare entity.Case presentation:We reported a case of RIMFS under the left occipital scalp in a 20-year-old girl with a history of medulloblastoma surgery and radiotherapy in 2006.A total tumor resection was performed with preservation of the overlying scalp the underlying bone,and no adjuvant therapy was administered after the first operation.The postoperative pathological diagnosis was high-grade MFS.The tumor relapsed 6 months later,and then,a planned extensive resection with negative surgical margins was carried out,followed by radiotherapy.No relapse occurred in a 12-month postoperative follow-up.Conclusions:Planned gross total resection(GTR)with negative margins is the reasonable choice and footstone of other treatments for MFS.Ill-defined infiltrated borders and the complicated structures make it a great trouble to achieve total resection of MFS in the head and neck,so adjuvant radiotherapy and chemotherapy seem more necessary for these lesions.
