Benefits and Limitations of Volumetric Modulated Arc Therapy in Treating Bilateral Breast Cancer with Regional Lymph Nodes

Purpose: The study was performed comparing dosimetric characteristics of volumetric modulated arc therapy (VMAT) and field-in-field (FiF) techniques on a patient with synchronous bilateral breast carcinoma. Methods: The patients with bilateral breast cancer treatment were included in this study. A total dose of 40.05 Gy in 15 fractions was prescribed to the Planning Target Volume (PTV) of the whole bilateral breast cancer with the supraclavicular and infraclavicular nodes, with a complementary boost of 10 Gy in 4 fractions to the surgical bed (PTVboost). For both radiotherapy techniques, several VxGy parameters were analyzed for the PTVs, together with the Conformity index (CI), the Homogeneity index (HI) and the critical organs at risk (OARs), lungs and heart. Results: The patient was treated by the VMAT technique and the daily treatment time was less than 20 minutes with daily CBCT imaging. In the VMAT plan, the PTV 95% dose covered 38.89 ± 0.81 Gy, compared to 37.26 ± 1.02 Gy in the FiF technique. The VMAT plan improved the dose homogeneity index and lower dose in lung towards high dose region. Conclusion: The study demonstrates the viability of the VMAT technique in the treatment of bilateral breast cancer. The introduced single isocentric VMAT technique is fast to deliver and it increases the dose homogeneity of the target volume with some limitations. The treatment was well tolerated, without interruption of the treatment courses caused by treatment-related toxicities.

THE NINTH FIVE-YEAR PLAN AND LONG-TERM TARGET BY 2010 FOR CHINA'S FOOD INDUSTRY

The"Ninth Five-Year Plan for theNational Economy and SocialDevelopment and the Long-TermTarget by the Year 2010" adopted at theFourth Session of the Eighth National People’sCongress have opened up a vast new worldfor the development of China’s food industry.The food industry should seize the opportunityto strengthen itself and speed up itsdevelopment for meeting the needs ofimproving the people’s living standards andperform well in modernized socialistconstruction.

Quadratic Programming-based Approach for Autonomous Vehicle Path Planning in Space

Path planning for space vehicles is still a challenging problem although considerable progress has been made over the past decades.The major difficulties are that most of existing methods only adapt to static environment instead of dynamic one,and also can not solve the inherent constraints arising from the robot body and the exterior environment.To address these difficulties,this research aims to provide a feasible trajectory based on quadratic programming（QP） for path planning in three-dimensional space where an autonomous vehicle is requested to pursue a target while avoiding static or dynamic obstacles.First,the objective function is derived from the pursuit task which is defined in terms of the relative distance to the target,as well as the angle between the velocity and the position in the relative velocity coordinates（RVCs）.The optimization is in quadratic polynomial form according to QP formulation.Then,the avoidance task is modeled with linear constraints in RVCs.Some other constraints,such as kinematics,dynamics,and sensor range,are included.Last,simulations with typical multiple obstacles are carried out,including in static and dynamic environments and one of human-in-the-loop.The results indicate that the optimal trajectories of the autonomous robot in three-dimensional space satisfy the required performances.Therefore,the QP model proposed in this paper not only adapts to dynamic environment with uncertainty,but also can satisfy all kinds of constraints,and it provides an efficient approach to solve the problems of path planning in three-dimensional space.

Target for Power Construction in 9th Five-year Plan Period Set-up

According to the National Meeting on Power Construction and Cost Control held in Beijing on 26th August 1996, the target for power construction in the period of 9th Five- year Plan is set-up as follows:

China Attains Targets in National Human Rights Action Plan

In April 2009, after receiving ap- proval from the State Council, the Information Office of the State Council published the NationalHuman Rights Action Plan of China （2009-2010）. It is China＇s first national plan on the theme of human rights, and serves as a policy document of the current stage for advancing China＇s human rights in a comprehensive way. It is an important move to implement the constitutional principle of respect- ing and safeguarding human rights, and to promote sustainable development and social harmony. It is also a solemn commitment to the world made by the Chinese government on human rights.

Clinical Experience and Dosimetry Outcome in Treating Breast Cancer with Field-in-Field Technique

Purpose: The study is aimed to establish the dosimetric characteristics of field-in-field (FiF) technique for carcinoma of breast treatment in Nepal. We assumed that FIF technique may result in improved dose distribution and reduced acute toxicity in these patients. Methods: Forty breast cancer patients participated in this study. A total dose of 50 Gy in 25 fractions was prescribed to the planning target volume. FiF plan was generated in treatment planning system. Dose volume histograms were evaluated for PTV and organs at risks. Several parameters were analyzed for the PTVs and organ at risks (OARs) together with the Conformity index (CI), and the Homogeneity index (HI). Results: The dose coverage of breast volume was achieved. The V95% (volume of 95%) of PTV covered D95% (Dose of 95%). The PTV dose was covered to 49.98 ± 0.9 Gy and 49.81 ± 1.1 Gy for the left and right breast, respectively. The mean lung dose was 14.87 ± 0.91 Gy. The homogeneity index (0.26 ± 0.17 and 0.22 ± 0.13) and conformity index (1.59 ± 0.75 and 1.36 ± 0.45) were analyzed for left and right breast, respectively. Conclusion: The study supports the viability of FiF technique in the treatment of breast cancer in Nepal. The FIF technique enables better dose distribution in the PTV and reduces dose to OARs. The FiF technique provides dosimetric advantages and requires less planning time.

Optimal Investment Strategy of Target Benefit Pension Plan Based on Random Inflation and Intergenerational Risk

In this paper,based on the stochastic optimal control method,the intergenerational risk and inflation risk,the optimal investment strategy of the target benefit pension plan is investigated on the basis of measuring the random wage rate under the random mortality and inflation risk of the personnel in the plan and the correlation between the wage change and the fluctuation of the financial market.The research shows that the financial market parameters and wage rate have a great influence on the optimal investment strategy,and gives the optimal investment strategy and the optimal income adjustment strategy of the target benefit pension.The research of this paper provides a reference for the policy formulation and implementation of the Target Benefit Pension Plan in our country.

Harvard Plan Targets Low-Income Students

美国哈佛大学向美国的贫困或中等收入的家庭发出了一个信息:Wewant to send the strongest possible message that Harvard is open to talentedstudents from all economic backgrounds.所谓贫困家庭的学生,英语有一个委婉说法:students from disadvantaged(贫困的)backgrounds。其标准是:家庭的年收入在40,000到60,000美元之间。该大学将如何在经济上“照顾”这些学子呢?文章讲得很清楚,包括以下方面:it will waive(放弃)application fees,payfor travel for campus visits and make funds available for books,winter clothing,medical care and other extraordinary expenses.本文还出现了一个精彩表达,似乎一下子很难译成汉语:colleges with competitive admissions(在招生方面具有竞争力的学校)