Background: Scarring alopecia like discoid lupus erythematosus, lichenplanopilaris and scarring folliculitis are common skin problems where differentiations between them are often difficult in many cases. Objective: T...Background: Scarring alopecia like discoid lupus erythematosus, lichenplanopilaris and scarring folliculitis are common skin problems where differentiations between them are often difficult in many cases. Objective: To report, study and evaluate cases of lichen planopilaris and characterize the different clinical points in favor of this disease. Patients and Methods: This case series descriptive study was done at Department of Dermatology-Baghdad Teaching Hospital from January 2010 to November 2012. Sixty seven patients were included where histological and dermatological examinations were carried out to all patients regarding all relevant points related to the disease. Punch biopsies were performed from ten patients for histopathological study. Results: The mean age of onset of the disease was 36.7 ± 5 years with a mean duration of the disease being 4.4 ± 3 years. The male to female ratio was 1.4:1. The characteristic lesions were pigmented scarring moth eaten alopecia surrounded by pigmented hyperkeratotic follicular papules involving mainly the fronto-vertical and parietal scalp. Conclusions: Lichen planopilaris is a common cause of scalp scarring alopecia in adult and it has many characteristic clinical features which can facilitate differentiation from other pathologic scalp conditions like discoid lupus erythematosus.展开更多
Objective:Lichen planopilaris (LPP) is a rare skin disorder,but it is also the most common cause of scarring alopecia in adults.The main cause of this disease is unknown,but it is considered to be related to the immun...Objective:Lichen planopilaris (LPP) is a rare skin disorder,but it is also the most common cause of scarring alopecia in adults.The main cause of this disease is unknown,but it is considered to be related to the immune status of the body.Several comorbidities are reportedly associated with LPP,such as hypertension,depression,thyroiditis,diabetes,and vitiligo.In the present study,we aimed to investigate the frequency of comorbidities in patients with LPP who were referred to Razi Hospital in Rasht,Iran,from 2016 to 2019.Methods:This cross-sectional study involved 60 patients with cicatricial alopecia patches (scarring and irreversible) and clinical signs and symptoms consistent with active LPP.The association between demographic data and comorbidities in patients with LPP was evaluated with the chi-square test andt test.Results:The results showed that the most common comorbidities were vitamin D deficiency (24.3%),hypothyroidism (17.6%),anemia (16.2%),asthma and allergy (14.8%),hypertension (13.5%),diabetes (9.5%),and vitiligo (4.5%).There was no statistically significant association of sex,age,or body mass index with LPP according to the presence or absence of underlying disease (P = 0.440,P = 0.108,andP = 0.340,respectively);however,there was a statistically significant difference in the presence of comorbidities according to age (P = 0.018).Conclusion:The results illustrated that women with vitamin D deficiency are more prone to LPP than are patients with other pre-existing underlying diseases.展开更多
Frontal fibrosing alopecia(FFA) is a recently described form of primary cicatricial alopecia, characterized by progressive recession of the frontotemporal hairline and eyebrow loss, occurring predominantly in postmeno...Frontal fibrosing alopecia(FFA) is a recently described form of primary cicatricial alopecia, characterized by progressive recession of the frontotemporal hairline and eyebrow loss, occurring predominantly in postmenopausal women. The incidence of FFA has increased significantly during the last decade and we may be facing an epidemic of the disease. Because this condition causes permanent hair loss, prompt diagnosis and treatment are essential for obtaining optimal outcome. This article reviews existing knowledge on epidemiology, etiopathogenesis, clinico-histological features, diagnosis,and treatment modalities of FFA.展开更多
文摘Background: Scarring alopecia like discoid lupus erythematosus, lichenplanopilaris and scarring folliculitis are common skin problems where differentiations between them are often difficult in many cases. Objective: To report, study and evaluate cases of lichen planopilaris and characterize the different clinical points in favor of this disease. Patients and Methods: This case series descriptive study was done at Department of Dermatology-Baghdad Teaching Hospital from January 2010 to November 2012. Sixty seven patients were included where histological and dermatological examinations were carried out to all patients regarding all relevant points related to the disease. Punch biopsies were performed from ten patients for histopathological study. Results: The mean age of onset of the disease was 36.7 ± 5 years with a mean duration of the disease being 4.4 ± 3 years. The male to female ratio was 1.4:1. The characteristic lesions were pigmented scarring moth eaten alopecia surrounded by pigmented hyperkeratotic follicular papules involving mainly the fronto-vertical and parietal scalp. Conclusions: Lichen planopilaris is a common cause of scalp scarring alopecia in adult and it has many characteristic clinical features which can facilitate differentiation from other pathologic scalp conditions like discoid lupus erythematosus.
文摘Objective:Lichen planopilaris (LPP) is a rare skin disorder,but it is also the most common cause of scarring alopecia in adults.The main cause of this disease is unknown,but it is considered to be related to the immune status of the body.Several comorbidities are reportedly associated with LPP,such as hypertension,depression,thyroiditis,diabetes,and vitiligo.In the present study,we aimed to investigate the frequency of comorbidities in patients with LPP who were referred to Razi Hospital in Rasht,Iran,from 2016 to 2019.Methods:This cross-sectional study involved 60 patients with cicatricial alopecia patches (scarring and irreversible) and clinical signs and symptoms consistent with active LPP.The association between demographic data and comorbidities in patients with LPP was evaluated with the chi-square test andt test.Results:The results showed that the most common comorbidities were vitamin D deficiency (24.3%),hypothyroidism (17.6%),anemia (16.2%),asthma and allergy (14.8%),hypertension (13.5%),diabetes (9.5%),and vitiligo (4.5%).There was no statistically significant association of sex,age,or body mass index with LPP according to the presence or absence of underlying disease (P = 0.440,P = 0.108,andP = 0.340,respectively);however,there was a statistically significant difference in the presence of comorbidities according to age (P = 0.018).Conclusion:The results illustrated that women with vitamin D deficiency are more prone to LPP than are patients with other pre-existing underlying diseases.
文摘Frontal fibrosing alopecia(FFA) is a recently described form of primary cicatricial alopecia, characterized by progressive recession of the frontotemporal hairline and eyebrow loss, occurring predominantly in postmenopausal women. The incidence of FFA has increased significantly during the last decade and we may be facing an epidemic of the disease. Because this condition causes permanent hair loss, prompt diagnosis and treatment are essential for obtaining optimal outcome. This article reviews existing knowledge on epidemiology, etiopathogenesis, clinico-histological features, diagnosis,and treatment modalities of FFA.
