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Chemical compositions and pharmacological activities ofXanthium strumarium
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作者 Ruoming Li Yunpeng Yan +4 位作者 Xiaomeng Zhangc Yibo Wang Wenhan Wang Yao Zhao Yu Chen 《Asian Journal of Traditional Medicines》 2024年第6期342-352,共11页
Xanthium strumarium(X.strumarium)is a traditional Chinese medicine with a long history.In recent years,with the development of modern pharmacology and chemical analysis technology,research on X.strumarium has been dee... Xanthium strumarium(X.strumarium)is a traditional Chinese medicine with a long history.In recent years,with the development of modern pharmacology and chemical analysis technology,research on X.strumarium has been deepend.This paper aims to systematically summarize the chemical compositions and pharmacological effects of X.strumarium,in order to provide theoretical basis and reference for further exploration in its clinical application and drug development. 展开更多
关键词 Xanthium strumarium chemical composition pharmacological activities
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Chemical composition and pharmacological activities of Atractylodes lancea:A review
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作者 Shuo Wanga Yunpeng Yang +3 位作者 Yibo Wang Wenhan Wang Meng Zhang Yu Chen 《Asian Journal of Traditional Medicines》 2024年第3期159-171,共13页
Atractylodes lancea(called Cangzhu in China)is a medicinal plant that has long been used as tonic agent in various ethno-medical systems in East Asia,especially in China,for the treatment of gastrointestinal dysfuncti... Atractylodes lancea(called Cangzhu in China)is a medicinal plant that has long been used as tonic agent in various ethno-medical systems in East Asia,especially in China,for the treatment of gastrointestinal dysfunction,cancer,osteoporosis,obesity and fetal irritability.We used the TCMSP database to search for the main active ingredients and traditional Chinese medicine targets of Atractylodes macrocephala.There are a total of 38 related articles,of which 27 are closely related to chemical composition and activity.This study reviews the chemical components and pharmacological effects of A.lancea,aiming to provide reference for its further research and development. 展开更多
关键词 Atractylodes lancea chemical composition pharmacological activities
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Chemical composition and pharmacological activities of the Phellodendron chinense Schneid
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作者 Yi′an Shi Yunpeng Yang +3 位作者 Wenhan Wang Yibo Wan Yao Zhao Yu Chen 《Asian Journal of Traditional Medicines》 2024年第5期285-298,共14页
Phellodendron chinense Schneid(P.chinense),as a traditional Chinese medicine,is commonly used in clinical practice.It has the effects of drying dampness,clearing heat,detoxifying,purging fire,and reducing swelling.Its... Phellodendron chinense Schneid(P.chinense),as a traditional Chinese medicine,is commonly used in clinical practice.It has the effects of drying dampness,clearing heat,detoxifying,purging fire,and reducing swelling.Its main chemical components are flavonoids and alkaloids,which have various pharmacological effects such as lowering blood sugar,lowering blood pressure and immunosuppression.With the continuous development of modern science and technology,the research on P.chinense Schneid has increased.This study reviews the chemical components and pharmacological effects of P.chinense Schneid,and provides reference for its further research and development. 展开更多
关键词 Phellodendron chinense Schneid chemical composition pharmacological activity
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Chemical constituents and pharmacological effects of Lonicerae japonicae
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作者 Yunpeng Yang Dan Tian +3 位作者 Yibo Wang Yi’an Shi Yuntian Xing Yu Chen 《Asian Journal of Traditional Medicines》 2024年第1期34-45,共12页
Lonicera japonica,also known as honeysuckle,is an evergreen shrub in the family of Syzygium.By consulting Sciencedirect databases and Web of Science databases,79 related articles were found,of which 22 were related to... Lonicera japonica,also known as honeysuckle,is an evergreen shrub in the family of Syzygium.By consulting Sciencedirect databases and Web of Science databases,79 related articles were found,of which 22 were related to chemical composition and pharmacological activity.These articles show that L.japonica has a wide range of pharmacological activities,including antiviral,anti-tumor,and antioxidant effects.These activities have important applications in the pharmaceutical,food,and fragrance industries.This review focuses on the chemical composition and pharmacological effects of L.japonicae,which is of great significance to the development of new drugs and therapeutic methods. 展开更多
关键词 Lonicerae japonicae chemical composition pharmacological activity
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Chemical constituents and pharmacological effects of Croton crassifolius
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作者 Luyan Yang Yibo Wang +4 位作者 Xinyao Wang Xiaoxia Xu Yunpeng Yang Meng Zhang Yu Chen 《Asian Journal of Traditional Medicines》 2024年第2期99-114,共16页
Croton crassifolius(CC)is a kind of traditional Chinese medicine rich in terpenoids,with among which diterpene species are the most.CC had biological activities in the treatment of cancer,inflammation,ulcerative colit... Croton crassifolius(CC)is a kind of traditional Chinese medicine rich in terpenoids,with among which diterpene species are the most.CC had biological activities in the treatment of cancer,inflammation,ulcerative colitis,osteoporosis and Alzheimer’s disease.This study reviews the chemical compositions and pharmacological activities of CC to provide reference for further research. 展开更多
关键词 Croton crassifolius chemical compositions pharmacological activities
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Summary of Chemical Constituents and Pharmacological Effects of Essential Oil of Sweet Orange from Southern Jiangxi Province
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作者 Jing Zhang Yuhao Liu Wenjing Zong 《Journal of Clinical and Nursing Research》 2024年第12期118-124,共7页
Gannan sweet orange essential oil has garnered significant attention due to its diverse chemical composition and pharmacological activities.The main active ingredients include sabinene,limonene,and linalool,which exhi... Gannan sweet orange essential oil has garnered significant attention due to its diverse chemical composition and pharmacological activities.The main active ingredients include sabinene,limonene,and linalool,which exhibit antioxidant,anti-inflammatory,antibacterial,and analgesic properties.This essential oil has potential applications in the development of medicinal products.This paper reviews the primary chemical composition and pharmacological effects of Jiangxi orange flower essential oil,highlighting the need for future research to focus on its biological activity and clinical application potential.Additionally,it emphasizes the importance of optimizing extraction and detection technologies to enhance its application value in medicine and other industries,thereby promoting the development of Gannan’s sweet orange industry. 展开更多
关键词 Gannan sweet orange Sweet orange essential oil chemical composition pharmacological activity
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An updated review on pharmacological activities and phytochemical constituents of evening primrose(genus Oenothera) 被引量:1
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作者 Rebecca Munir Nabil Semmar +1 位作者 Muhammad Farman Naseem Saud Ahmad 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第11期1046-1054,共9页
Genus Oenothera includes medicinal plants that are distributed throughout the world and are known since ancient times. Popular indications of different species of this genus include treatment of inflammations, diabete... Genus Oenothera includes medicinal plants that are distributed throughout the world and are known since ancient times. Popular indications of different species of this genus include treatment of inflammations, diabetes, microbial infections, ulcers, tumors, kidney and liver problems. The plants of this genus are a botanical source for various pharmaceutically active components like sterols, alkaloids, phenolic acids, flavonoids, triterpenoids, saponins, biflavonols and tocopherols. This review article is a compilation of chemical composition and biological activities of the various species of the genus Oenothera. 展开更多
关键词 OENOTHERA Medicinal plants chemical composition Biological activities
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Chemical composition and pharmacological activities of Polygonum cuspidatum
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作者 Yi’an Shi Luming Pan +4 位作者 Jiayi Bi Xuefei Yang Jing Sun Meng Zhang Yu Chen 《Asian Journal of Traditional Medicines》 CAS 2022年第3期108-115,共8页
Polygonum cuspidatum is a traditional Chinese medicine,and its medicinal part is dry rhizome.It is mainly used to treat damp heat jaundice,burns,carbuncle,ulcer poisoning,amenorrhea,and snake bite.Recent studies have ... Polygonum cuspidatum is a traditional Chinese medicine,and its medicinal part is dry rhizome.It is mainly used to treat damp heat jaundice,burns,carbuncle,ulcer poisoning,amenorrhea,and snake bite.Recent studies have found that P.cuspidatum also contains active ingredients against coronaviruses.This paper reviews the chemical constituents and pharmacological activities of P.cuspidatum,so as to provide a scientific basis for the development and utilization of P.cuspidatum resources in the future. 展开更多
关键词 Polygonum cuspidatum chemical composition pharmacological activity
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Advances in Chemical Constituents and Pharmacological Activity of Pholidota spp.
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作者 Xiucai WU Shuang LIANG Zhengying SU 《Medicinal Plant》 CAS 2020年第2期13-15,共3页
In recent years,a large number of studies have shown that the effective compounds extracted from Pholidota spp.have pharmacological activities such as anesthesia,analgesia,anti-fatigue,anti-hypoxia,anti-tumor and anti... In recent years,a large number of studies have shown that the effective compounds extracted from Pholidota spp.have pharmacological activities such as anesthesia,analgesia,anti-fatigue,anti-hypoxia,anti-tumor and anti-oxidant.Because of significant activity and small side effects,Pholidota spp.have attracted much attention.In this article,the effective chemical constituents and pharmacological activity of Pholidota spp.are reviewed comprehensively in order to provide reference for the further rational development of Pholidota spp.and development of new drugs. 展开更多
关键词 Pholidota spp. MEDICINAL PLANT chemical CONSTITUENT pharmacological activity
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A review of research on the chemical constituents and pharmacological effects of Elephantopus tomentosus L.
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作者 Shuai Shen Ming Bai Shaojiang Song 《Asian Journal of Traditional Medicines》 CAS 2023年第1期15-24,共10页
Elephantopus tomentosus,belonging to the genus Elephantopus,is widely distributed in the coastal areas of southern China and tropical regions,used locally as traditional folk medicine.Previous phytochemistry studies o... Elephantopus tomentosus,belonging to the genus Elephantopus,is widely distributed in the coastal areas of southern China and tropical regions,used locally as traditional folk medicine.Previous phytochemistry studies on Elephantopus tomentosus led to the isolation of sesquiterpenoids,triterpenoids,flavonoids and other compounds.Research has shown that these compounds possess multiple biological activities,which have attracted great attention of researchers worldwide.This study reviews the chemical constituents and biological activities of the Elephantopus tomentosus in order to better explore and utilize Elephantopus tomentosus. 展开更多
关键词 Elephantopus tomentosus chemical composition pharmacological activities SESQUITERPENOIDS
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Volatile oil from Litsea lancilimba Merr.: a review of its chemical structure and biological activity 被引量:1
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作者 Yijie Zhang Ming Bai +2 位作者 Weiyu Zhou Xiaoxiao Huang Shaojiang Song 《Asian Journal of Traditional Medicines》 CAS 2022年第4期181-185,共5页
Litsea lancilimba Merr.is a Cinnamomum plant of Lauraceae.Phytochemical investigations of the Litsea lancilimba Merr.have resulted in the isolation of Volatile oil,flavonoid glycosides,tannins,alkaloids,lignans,organi... Litsea lancilimba Merr.is a Cinnamomum plant of Lauraceae.Phytochemical investigations of the Litsea lancilimba Merr.have resulted in the isolation of Volatile oil,flavonoid glycosides,tannins,alkaloids,lignans,organic acids and so on.Studies have showed that volatile oil is the main chemical component.Recent trials have demonstrated the efficacy of Litsea lancilimba Merr.in strengthening the function of stomach.The fruits have also been demonstrated to possess anti-inflammatory and bacteriostatic activities.This review deals mainly with the chemical structure and biological activities of Litsea lancilimba Merr.oil. 展开更多
关键词 Litsea lancilimba Merr. volatile oil chemical composition pharmacological activity
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基于UPLC-Q-TOF-MS/MS和网络药理学探究尖尾芋抗乳腺癌作用机制
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作者 王鹏 陈娅 +4 位作者 彭兰淳 郑青竹 陈厅 彭江丽 彭求贤 《天然产物研究与开发》 CAS CSCD 北大核心 2024年第4期675-693,共19页
本研究通过UPLC-Q-TOF-MS/MS技术、网络药理学策略探究尖尾芋石油醚部位抗乳腺癌药效物质基础及作用机制,并通过4T1乳腺癌荷瘤小鼠模型验证尖尾芋石油醚部位(petroleum ether fraction of Alocasia cucullata,EAC)体内抗乳腺癌作用及机... 本研究通过UPLC-Q-TOF-MS/MS技术、网络药理学策略探究尖尾芋石油醚部位抗乳腺癌药效物质基础及作用机制,并通过4T1乳腺癌荷瘤小鼠模型验证尖尾芋石油醚部位(petroleum ether fraction of Alocasia cucullata,EAC)体内抗乳腺癌作用及机制。基于UPLC-Q-TOF-MS/MS数据获取EAC化学成分41个,包括11种芳香类成分、8种萜类成分、5种生物碱类成分、4种脂肪酸类成分、2种香豆素类成分和11种其他类成分;基于鉴定出的化合物通过网络药理学得到556个潜在作用靶点;蛋白互作网络(PPI)分析发现MAPK1、Bcl-2等10个核心靶点,富集分析发现核心靶点可能通过MAPK、PI3K-Akt等细胞凋亡相关信号通路发挥抗乳腺癌作用,并通过分子对接技术验证了毛地黄毒苷配基等活性成分与细胞凋亡相关蛋白pERK、Bcl-2、Bax具有良好的结合能力。抗乳腺癌活性研究结果表明与模型对照组比较,EAC低、中、高剂量组肿瘤生长趋势渐缓,肿瘤质量减少,抑瘤率逐渐增加;EAC中、高剂量组脾脏指数有显著性差异,EAC低剂量组脾脏指数效果不显著(P<0.05);HE染色观察到给药组肿瘤组织中细胞排列疏松,轮廓不清晰。ELISA法检测小鼠血清,发现EAC高、中剂量组、5-氟尿嘧啶阳性对照组的IL-1β、TNF-α含量均降低。动物验证实验结果表明不同浓度EAC均能下调MAPKs信号通路中p-ERK蛋白的表达(P<0.01),而对ERK、JNK、p-38、p-JNK、p-p38蛋白水平无显著性差异;EAC能显著升高小鼠乳腺癌组织中Bax/Bcl-2蛋白水平和基因表达水平。综上,尖尾芋石油醚部位能下调p-ERK蛋白水平,促进癌细胞凋亡从而抑制4T1乳腺癌荷瘤小鼠肿瘤的生长。 展开更多
关键词 尖尾芋 石油醚部位 抗乳腺癌活性 化学成分 网络药理学 MAPKS信号通路
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Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenes
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作者 Ye Jin Yanqing Xie +3 位作者 Peng Zhang Afsar Khan Zhihong Zhou Lu Liu 《Chinese Herbal Medicines》 CAS 2024年第1期70-81,共12页
The seco-prezizaane-type sesquiterpenes(SPS),as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers,are isolated from the genus Illicium,which have a... The seco-prezizaane-type sesquiterpenes(SPS),as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers,are isolated from the genus Illicium,which have a variety of biological activities,including neurotoxicity and neurotrophic effects,etc.This review summarizes the chemical constituents and pharmacological effects of SPS,and discusses the potential trend and scope of future research. 展开更多
关键词 anisatin chemical composition Illicium genus majucin pharmacological activity seco-prezizaane-type sesquiterpenes
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生姜、干姜、炮姜的性效考证及其化学成分、药理活性的研究进展 被引量:6
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作者 杨秀娟 王佳佳 +5 位作者 郭晶晶 李硕 杨志军 隋峰 田一虹 李越峰 《中药新药与临床药理》 CAS CSCD 北大核心 2024年第4期595-605,共11页
生姜为姜科植物姜的新鲜根茎,属于药食两用品,作为中药首次收载于《神农本草经》,而汉·张仲景《金匮要略》最早记载了生姜在中医临床中的应用。干姜、炮姜分别是生姜经干燥加工和砂烫后的炮制品,三者在临床上被广泛使用,但在药物... 生姜为姜科植物姜的新鲜根茎,属于药食两用品,作为中药首次收载于《神农本草经》,而汉·张仲景《金匮要略》最早记载了生姜在中医临床中的应用。干姜、炮姜分别是生姜经干燥加工和砂烫后的炮制品,三者在临床上被广泛使用,但在药物属性和作用特点上却有所不同。基于不同历史时期的不同医家对三者的性效和应用的记载并不完全一致,该文从古籍本草考证、现代化学成分和药理作用等方面对生姜、干姜、炮姜(三姜)进行了总结,以系统地综述三姜的性效源流及现代研究进展,明确其临床应用范畴,为三姜性效的深入研究提供参考,亦为中医临床合理用药提供个性化参考。 展开更多
关键词 生姜 干姜 炮姜 药性 功效 本草考证 化学成分 药理活性
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Research progress and quality markers prediction analysis of Dysosma versipellis
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作者 Yuan-Hui Guo Peng Lu +4 位作者 Jia-Xing He Bao-Nan Ma Ebuka-Olisaemeka Nwafor Wen-Xin Wang Chuan-Xin Liu 《Traditional Medicine Research》 2023年第3期36-50,共15页
Dysosma versipellis is the rhizome of Bajiaolian in Berberaceae.It is a unique medicinal plant in China and it was the first to be recorded in Shennong’s Classic of Materia Medica(unknown author,25–220 C.E.).It has ... Dysosma versipellis is the rhizome of Bajiaolian in Berberaceae.It is a unique medicinal plant in China and it was the first to be recorded in Shennong’s Classic of Materia Medica(unknown author,25–220 C.E.).It has complex chemical components as well as complex,pharmacological and toxicological effects are extensive.Based on the recent research progress,the chemical constituents,pharmacological activities and toxicological effects of Dysosma versipellis were summarized.Combined with the core concept of quality markers of traditional Chinese medicine,the prediction and analysis were carried out from the aspects of phytogenetics and the source pathway of specific chemical constituents,traditional medicinal properties,traditional efficacy,chemical composition measurability,blood components,and pharmacokinetics,in order to provide reference for further study of Dysosma versipellis. 展开更多
关键词 Dysosma versipellis lignans FLAVONOIDS chemical composition pharmacological activity toxicological effect quality marker podophyllotoxin KAEMPFEROL QUERCETIN
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Research progress of Cassytha filiformis L
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作者 Zi-Bao Huang Lu Zhang +3 位作者 Lin Dong Xiao-Po Zhang Li-Fang Han Cai-Yun Zhang 《Journal of Hainan Medical University》 2022年第12期59-64,共6页
Cassytha filiformis L,belonging to family Lauraceae,is widely distributed in subtropical and tropical regions.Cassytha filiformis L is a traditional plant medicine in China,it has proved that the plant showed anti-par... Cassytha filiformis L,belonging to family Lauraceae,is widely distributed in subtropical and tropical regions.Cassytha filiformis L is a traditional plant medicine in China,it has proved that the plant showed anti-parasite,anti-tumor,anti-diabetic and anti-platelet aggregation activities,so far,the main pharmacological active components are alkaloids.In this paper,the chemical constituents and pharmacological effects of Cassytha filiformis L were reviewed by referring to databases such as CNKI,Vip and Pubmed,so as to lay a foundation for its development and utilization. 展开更多
关键词 Cassytha filiformis L chemical composition pharmacological activity ALKALOIDS
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Advances in Studies on Total Flavone of Abelmoschus manihot(L.)Medic.
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作者 Lei ZHOU 《Medicinal Plant》 CAS 2021年第5期93-96,共4页
Flos Abelmoschus manihot has a long history of application.Recent studies show that total flavone of A.manihot(L.)Medic(TFA)has a wide range of pharmacological activity.This article is a review mainly on chemical comp... Flos Abelmoschus manihot has a long history of application.Recent studies show that total flavone of A.manihot(L.)Medic(TFA)has a wide range of pharmacological activity.This article is a review mainly on chemical composition,method of determination and pharmacologic action of TFA,and it raises research and development direction. 展开更多
关键词 Total flavone of Abelmoschus manihot(L.)Medic(TFA) chemical composition Method of determination pharmacological activity
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钩藤化学成分和药理作用研究进展 被引量:4
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作者 张晓娟 左冬冬 于孙婉琪 《中医药信息》 2024年第2期81-86,共6页
钩藤始载于《名医别录》,应用历史悠久。本文查阅钩藤化学成分和药理作用的相关研究文献,发现钩藤主要含有生物碱类、三萜类、酚类、甾醇类、黄酮类、醌类、香豆素类和木脂素类等成分,具有降压、抗氧化应激、抗神经细胞凋亡、调节炎症... 钩藤始载于《名医别录》,应用历史悠久。本文查阅钩藤化学成分和药理作用的相关研究文献,发现钩藤主要含有生物碱类、三萜类、酚类、甾醇类、黄酮类、醌类、香豆素类和木脂素类等成分,具有降压、抗氧化应激、抗神经细胞凋亡、调节炎症因子及其相关通路、降脂、抗脑缺血再灌注损伤、抗纤维化、抗抑郁、抗癌和调整肠道菌群等作用,主要作用于心血管和中枢神经系统,通过调节RhoA/ROCK1、ERK/MAPK、p38MAPK/MAPK、JNK/MAPK、Akt/eNOS、PI3K/Akt、ERK1/2、p27Kip1、PI3K/Akt/GSK-3β、Src/STAT3和HIF-1α/EMT信号通路,发挥治疗高血压、阿尔茨海默病、帕金森、肺纤维化等疾病的作用。 展开更多
关键词 钩藤 化学成分 药理作用
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赶黄草化学成分及药理活性研究进展
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作者 吕晶 田新强 +1 位作者 项峥 陈长兰 《辽宁大学学报(自然科学版)》 CAS 2024年第2期121-129,共9页
赶黄草(Penthorum chinense Pursh)为传统苗族药物,是一种民间用于预防治疗肝病的“药食同源”植物,性温味甘,具有清热解毒、利水消肿、平肝等功效.现代天然药物化学研究表明,赶黄草含有丰富的活性成分,包括黄酮类、木脂素类、有机酸类... 赶黄草(Penthorum chinense Pursh)为传统苗族药物,是一种民间用于预防治疗肝病的“药食同源”植物,性温味甘,具有清热解毒、利水消肿、平肝等功效.现代天然药物化学研究表明,赶黄草含有丰富的活性成分,包括黄酮类、木脂素类、有机酸类、香豆素类等化学成分,具有抗肿瘤、抗氧化、抗炎和肝损伤的保护作用等多种药理活性,药食用价值较高.近年来,虽然赶黄草的化学成分及其药理作用研究逐渐深入,然而相关综述较少.本文对国内外研究成果进行了综述,以期为赶黄草的药理作用机制研究及“药食同源”新型保健产品的开发提供参考. 展开更多
关键词 赶黄草 化学成分 药理活性 药食同源
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杜仲叶化学成分、药理活性及现代应用研究进展 被引量:2
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作者 李婉玉 张家旭 +1 位作者 谢兴文 石晓峰 《天然产物研究与开发》 CAS CSCD 北大核心 2024年第5期900-917,共18页
杜仲叶是一种传统中药,现收录于《中华人民共和国药典》一部,同时其作为一种药食两用中药,具有较高的研究价值和开发潜力。现代研究表明,杜仲叶主要含有黄酮类、酚酸类、木脂素类、环烯醚萜类等化学成分,具有抗氧化、降血压、降血脂、... 杜仲叶是一种传统中药,现收录于《中华人民共和国药典》一部,同时其作为一种药食两用中药,具有较高的研究价值和开发潜力。现代研究表明,杜仲叶主要含有黄酮类、酚酸类、木脂素类、环烯醚萜类等化学成分,具有抗氧化、降血压、降血脂、神经保护和骨保护等药理作用。目前已研制和开发出较多以杜仲叶为主药或原料的药品、保健品和食品,在医疗、化工和养殖业等多个领域均有应用。该文通过检索近20年国内外对杜仲叶的相关研究报道,对其化学成分、药理活性和应用进行整理总结,为后续杜仲叶的研究及资源开发提供科学依据。 展开更多
关键词 杜仲叶 化学成分 药理活性 开发利用
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