Plasma equilibrium reconstruction provides essential information for tokamak operation and physical analysis.An extensive and reliable set of magnetic diagnostics is required to obtain accurate plasma equilibrium.This...Plasma equilibrium reconstruction provides essential information for tokamak operation and physical analysis.An extensive and reliable set of magnetic diagnostics is required to obtain accurate plasma equilibrium.This study designs and optimizes the magnetic diagnostics layout for the reconstruction of the equilibrium of the plasma according to the scientific objectives,engineering design parameters,and limitations of the Chinese Fusion Engineering Test Reactor(CFETR).Based on the CFETR discharge simulation,magnetic measurement data are employed to reconstruct consistent plasma equilibrium parameters,and magnetic diagnostics'number and position are optimized by truncated Singular value decomposition,verifying the redundancy reliability of the magnetic diagnostics layout design.This provides a design solution for the layout of the magnetic diagnostics system required to control the plasma equilibrium of CFETR,and the developed design and optimization method can provide effective support to design magnetic diagnostics systems for future magnetic confinement fusion devices.展开更多
Plasma equilibrium has been calculated using an analytical method. The plasma profiles of the current density, safety factor, pressure and magnetic surface function are obtained. The analytical solution of the Grad–S...Plasma equilibrium has been calculated using an analytical method. The plasma profiles of the current density, safety factor, pressure and magnetic surface function are obtained. The analytical solution of the Grad–Shafranov(GS) equation is obtained by the variable separation method and compared with the computed results of the equilibrium fitting code EFIT.展开更多
In this work, a zero-dimensional plasma model for self-field magnetoplasmadynamic thrusters(SF-MPDTs) is proposed, which is based on the ion-number balance equation and energy balance equation, and can calculate the a...In this work, a zero-dimensional plasma model for self-field magnetoplasmadynamic thrusters(SF-MPDTs) is proposed, which is based on the ion-number balance equation and energy balance equation, and can calculate the average electron temperature and the average ion temperature inside the discharge chamber conveniently. At the same time, the model can also predict the thruster performance, and the thruster performance predicted by the model is compared with experimental results, which proved the reliability of the model.展开更多
Plasma equilibrium parameters such as position, X-point, internal inductance, and poloidal beta are essential information for efficient and safe operation of tokamak. In this work, the artificial neural network is use...Plasma equilibrium parameters such as position, X-point, internal inductance, and poloidal beta are essential information for efficient and safe operation of tokamak. In this work, the artificial neural network is used to establish a non-linear relationship between the measured diagnostic signals and selected equilibrium parameters. The estimation process is split into a preliminary classification of the kind of equilibrium(limiter or divertor) and subsequent inference of the equilibrium parameters. The training and testing datasets are generated by the tokamak simulation code(TSC), which has been benchmarked with the EAST experimental data. The noise immunity of the inference model is tested. Adding noise to model inputs during training process is proved to have a certain ability for maintaining performance.展开更多
Many magnetohydrodynamic stability analyses require generation of a set of equilibria with a fixed safety factor q-profile while varying other plasma parameters.A neural network(NN)-based approach is investigated that...Many magnetohydrodynamic stability analyses require generation of a set of equilibria with a fixed safety factor q-profile while varying other plasma parameters.A neural network(NN)-based approach is investigated that facilitates such a process.Both multilayer perceptron(MLP)-based NN and convolutional neural network(CNN)models are trained to map the q-profile to the plasma current density J-profile,and vice versa,while satisfying the Grad–Shafranov radial force balance constraint.When the initial target models are trained,using a database of semianalytically constructed numerical equilibria,an initial CNN with one convolutional layer is found to perform better than an initial MLP model.In particular,a trained initial CNN model can also predict the q-or J-profile for experimental tokamak equilibria.The performance of both initial target models is further improved by fine-tuning the training database,i.e.by adding realistic experimental equilibria with Gaussian noise.The fine-tuned target models,referred to as fine-tuned MLP and fine-tuned CNN,well reproduce the target q-or J-profile across multiple tokamak devices.As an important application,these NN-based equilibrium profile convertors can be utilized to provide a good initial guess for iterative equilibrium solvers,where the desired input quantity is the safety factor instead of the plasma current density.展开更多
A three-fluid equilibrium plasma with bulk plasma and energetic electrons has been observed on the Xuanlong-50(EXL-50) spherical torus, where the energetic electrons play a crucial role in sustaining the plasma curren...A three-fluid equilibrium plasma with bulk plasma and energetic electrons has been observed on the Xuanlong-50(EXL-50) spherical torus, where the energetic electrons play a crucial role in sustaining the plasma current and pressure. In this study, the equilibrium of a multi-fluid plasma was investigated by analyzing the relationship between the external vertical magnetic field(B_(V)),plasma current(I_(p)), the poloidal ratio(β_(p)) and the Shafranov formula. Remarkably, our research demonstrates some validity of the Shafranov formula in the presence of multi-fluid plasma in EXL-50 spherical torus. This finding holds significant importance for future reactors as it allows for differentiation between alpha particles and background plasma. The study of multi-fluid plasma provides a significant reference value for the equilibrium reconstruction of burning plasma involving alpha particles.展开更多
Solovev's approach of finding equilibrium solutions was found to be extremely useful for generating a library of linear-superposable equilibria for the purpose of shaping studies.This set of solutions was subseque...Solovev's approach of finding equilibrium solutions was found to be extremely useful for generating a library of linear-superposable equilibria for the purpose of shaping studies.This set of solutions was subsequently expanded to include the vacuum solutions of Zheng,Wootton and Solano,resulting in a set of functions{SOLOVEV_ZWS}that were usually used for all toroidally symmetric plasmas,commonly recognized as being able to accommodate any desired plasma shapes(complete-shaping capability).The possibility of extending the Solovev approach to toroidal equilibria with a general plasma flow is examined theoretically.We found that the only meaningful extension is to plasmas with a pure toroidal rotation and with a constant Mach number.We also show that the simplification ansatz made to the current profiles,which was the basis of the Solovev approach,should be applied more systematically to include an internal boundary condition at the magnetic axis;resulting in a modified and more useful set{SOLOVEV_ZWSm}.Explicit expressions of functions in this set are given for equilibria with a quasi-constant current density profile,with a toroidal flow at a constant Mach number and with specific heat capacity 1.The properties of{SOLOVEV_ZWSm}are studied analytically.Numerical examples of achievable equilibria are demonstrated.Although the shaping capability of the set{SOLOVE_ZWSm}is quite extensive,it nevertheless still does not have complete shaping capability,particularly for plasmas with negative curvature points on the plasma boundary such as the doublets or indented bean shaped tokamaks.展开更多
In this paper we present a coupled Finite Element Method–Boundary Element Method(FEM-BEM)approach for the solution of the free-boundary axi-symmetric plasma equilibrium problem.The proposed method,obtained from an i...In this paper we present a coupled Finite Element Method–Boundary Element Method(FEM-BEM)approach for the solution of the free-boundary axi-symmetric plasma equilibrium problem.The proposed method,obtained from an improvement of the Hagenow-Lackner coupling method,allows to efficiently model the equilibrium problem in unbounded domains by discretizing only the plasma region;the external conductors can be modelled either as 2D or 3D models,according to the problem of interest.The paper explores different iterative methods for the solution of the nonlinear Grad-Shafranov equation,such as Picard,Newton-Raphson and Newton-Krylov,in order to provide a robust and reliable tool,able to handle large-scale problems(e.g.high resolution equilibria).This method has been implemented in the FRIDA code(FReeboundary Integro-Differential Axisimmetric–https://github.om/matteobonotto/FRIDA),together with a suitable Adaptive Integration Technique(AIT)for the computation of the source term.FRIDA has been successfully tested and validated against experimental data from RFX-mod device,and numerical equilibria of an ITER-like device.展开更多
In the reaction of methane and carbon dioxide to C2 hydrocarbons under non-equilibrium plasma, methane conversion was decreased, but selectivity of C2 hydrocarbons was increased when using La2O3/?Al2O3 as catalyst. S...In the reaction of methane and carbon dioxide to C2 hydrocarbons under non-equilibrium plasma, methane conversion was decreased, but selectivity of C2 hydrocarbons was increased when using La2O3/?Al2O3 as catalyst. So the yield of C2 hydrocarbons was higher than using plasma alone. The synergism of La2O3/?Al2O3 and plasma gave methane conversion of 24.9% and C2 yield of 18.1%. The distribution of C2 hydrocarbons changed when Pd- La2O3/?Al2O3 was used as catalyst, the major C2 product was ethylene.展开更多
Catalysis and regeneration efficiency of granular activated carbon (GAC) and activated carbon fiber (ACF) were investigated in a non-equilibrium plasma water treatment reactor with a combination of pulsed streamer...Catalysis and regeneration efficiency of granular activated carbon (GAC) and activated carbon fiber (ACF) were investigated in a non-equilibrium plasma water treatment reactor with a combination of pulsed streamer discharge and GAC or ACF. The experimental results show that the degradation efficiency of methyl orange (MO) by the combined treatment can increase 22% (for GAC) and 24% (for ACF) respectively compared to pulsed discharge treatment alone, indicating that the combined treatment has a synergetic effect. The MO degradation efficiency by the combined treatment with pulsed discharge and saturated GAC or ACF can increase 12% and 17% respectively compared to pulsed discharge treatment alone. Both GAC and ACF show catalysis and the catalysis of ACF is prominent. Meanwhile, the regeneration of GAC and ACF are realized in this process. When H202 is introduced into the system, the utilization efficiency of ozone and ultraviolet light is improved and the regeneration efficiency of GAC and ACF is also increased.展开更多
A mini-type of plasma source was studied experimentally. The results showed that the plasma density, which was generated by an atmospheric non-equilibrium plasma source, rises with the increase in driving electric-fie...A mini-type of plasma source was studied experimentally. The results showed that the plasma density, which was generated by an atmospheric non-equilibrium plasma source, rises with the increase in driving electric-field and the momentum of gas particles. For a driving electricfield of 56 kV/cm and a gas particles' momentum of 10^9 × 10^-22 g·m/s, the ion density can exceed 10^10/cm^3 while the effective volume of the plasma source is only 2.5 cm^2. This study may help develop a method to generate a minitype plasma source with low energy consumption but high ion concentration. This source can be used in chemical industry, environmental engineering and military applications.展开更多
Magnetohydrodynamic (MHD) accelerator is proposed as a next generation propulsion system. It can be used to increase the performance of a propulsion system. The objective of this study is to investigate the performa...Magnetohydrodynamic (MHD) accelerator is proposed as a next generation propulsion system. It can be used to increase the performance of a propulsion system. The objective of this study is to investigate the performance of MHD accelerator using non-equilibrium air plasma as working gas. In this study, the fundamental performance of MHD accelerator such as flow performance and electrical performance is evaluated at different levels of applied magnetic field using I-D numerical simulation. The numerical simulation is developed based on a set of differential equations with MHD approximation. To solve this set of differential equations the MacCormack scheme is used. A specified channel designed and developed at NASA Marshall Space Flight Centre is used in the numerical simulation. The composition of the simulated air plasma consists of seven species, namely, N2, N, O2, O, NO, NO+, and e-. The performance of the non-equilibrium MHD accelerator is also compared with the equilibrium MHD accelerator.展开更多
A simple and selective ultra performance liquid chromatography--electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four...A simple and selective ultra performance liquid chromatography--electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four bioactive ftavonoids (such as orientin and vitexin) in Polygonum orientale. Protein precipitation was used for sample preparation. Equilibrium dialysis technique was applied to determine the plasma protein binding under physiological conditions. The separation was achieved through a Waters C i s column with a mobile phase composed of 0.1% formic acid in acetonitrile and 0.1% aqueous formic acid using step gradient elution at a flow rate of 0.35 mL/min. A Waters ACQUITYTM TQD system was operated under the multiple reaction monitoring (MRM) mode of positive electrospray ionization. All of the recovery, precision, accuracy and stability of the method met the requirements. Good correlations (r 〉 0.99) of the four compounds were found, which suggested that these compounds can be simultaneously determined with acceptable accuracy. Results showed that the plasma protein bindings of the four bioactive flavonoids were in the range of 74-89% over the six concentrations studied. The binding parameters containing protein binding affinity, protein binding dissociation constant, and protein binding site were studied. The maximum ability to bind with protein was also determined in the assay in order to understand the drug-protein binding of each compound better.展开更多
A code named LARWM with non-ideal magnetohydrodynamic equations in cylindrical model is used to describe the instability in Tokamak plasma surrounded by a conducting wall with finite resistivity. We mainly take three ...A code named LARWM with non-ideal magnetohydrodynamic equations in cylindrical model is used to describe the instability in Tokamak plasma surrounded by a conducting wall with finite resistivity. We mainly take three factors related to the shear equilibrium plasma flow into consideration to study the stabilizing effect of the shear flow on the resistive wall modes (RWMs). The three factors are the velocity amplitude of flow, the shear rate of flow on plasma surface, and the inertial energy of equilibrium plasma flow. In addition, a local shear plasma flow is also calculated by the LARWM code. Consequently, it is found that the inertial energy of the shear equilibrium plasma flow has an important role in the stabilization of the RWMs.展开更多
The equilibrium potential of fluffy dust grains in plasma are calculated for comet P/Halley and comet P/G-Z. It is found that the dust equilibrium potential linearly correlates with the logarithm of electron density. ...The equilibrium potential of fluffy dust grains in plasma are calculated for comet P/Halley and comet P/G-Z. It is found that the dust equilibrium potential linearly correlates with the logarithm of electron density. We propose this relationship can also be applied to comet Hale-Bopp.展开更多
Reconstruction of experimental axisymmetric equilibria is an important part of tokamak data analysis. Fourier expansion is applied to reconstruct the vessel current distribution in EFIT code. Benchmarking and testing ...Reconstruction of experimental axisymmetric equilibria is an important part of tokamak data analysis. Fourier expansion is applied to reconstruct the vessel current distribution in EFIT code. Benchmarking and testing calculations are performed to evaluate and validate this algorithm. Two cases for circular and non-circular plasma discharges are presented. Fourier expansion used to fit the eddy current is a robust method and the real time EFIT can be introduced to the plasma control system in the coming campaign.展开更多
基金Project supported by the National MCF Energy Research and Development Program of China (Grant Nos.2022YFE03010002,2018YFE0302100,and 2018YFE0301105)the National Natural Science Foundation of China (Grant Nos.11875291,11805236,11905256,and 12075285)。
文摘Plasma equilibrium reconstruction provides essential information for tokamak operation and physical analysis.An extensive and reliable set of magnetic diagnostics is required to obtain accurate plasma equilibrium.This study designs and optimizes the magnetic diagnostics layout for the reconstruction of the equilibrium of the plasma according to the scientific objectives,engineering design parameters,and limitations of the Chinese Fusion Engineering Test Reactor(CFETR).Based on the CFETR discharge simulation,magnetic measurement data are employed to reconstruct consistent plasma equilibrium parameters,and magnetic diagnostics'number and position are optimized by truncated Singular value decomposition,verifying the redundancy reliability of the magnetic diagnostics layout design.This provides a design solution for the layout of the magnetic diagnostics system required to control the plasma equilibrium of CFETR,and the developed design and optimization method can provide effective support to design magnetic diagnostics systems for future magnetic confinement fusion devices.
文摘Plasma equilibrium has been calculated using an analytical method. The plasma profiles of the current density, safety factor, pressure and magnetic surface function are obtained. The analytical solution of the Grad–Shafranov(GS) equation is obtained by the variable separation method and compared with the computed results of the equilibrium fitting code EFIT.
基金supported by National Natural Science Foundation of China (No. 11872093)。
文摘In this work, a zero-dimensional plasma model for self-field magnetoplasmadynamic thrusters(SF-MPDTs) is proposed, which is based on the ion-number balance equation and energy balance equation, and can calculate the average electron temperature and the average ion temperature inside the discharge chamber conveniently. At the same time, the model can also predict the thruster performance, and the thruster performance predicted by the model is compared with experimental results, which proved the reliability of the model.
基金Project supported by the National Magnetic Confinement Fusion Energy R&D Program of China(Grant No.2018YFE0302100)the National Key Research and Development Program of China(Grant Nos.2017YFE0300500 and 2017YFE0300501)+1 种基金the National Natural Science Foundation of China(Grant Nos.11575245,11805236,and 11905256)Young and Middle-aged Academic Back-bone Finance Fund from Anhui Medical University
文摘Plasma equilibrium parameters such as position, X-point, internal inductance, and poloidal beta are essential information for efficient and safe operation of tokamak. In this work, the artificial neural network is used to establish a non-linear relationship between the measured diagnostic signals and selected equilibrium parameters. The estimation process is split into a preliminary classification of the kind of equilibrium(limiter or divertor) and subsequent inference of the equilibrium parameters. The training and testing datasets are generated by the tokamak simulation code(TSC), which has been benchmarked with the EAST experimental data. The noise immunity of the inference model is tested. Adding noise to model inputs during training process is proved to have a certain ability for maintaining performance.
基金supported by National Natural Science Foundation of China (Nos. 12205033, 12105317, 11905022 and 11975062)Dalian Youth Science and Technology Project (No. 2022RQ039)+1 种基金the Fundamental Research Funds for the Central Universities (No. 3132023192)the Young Scientists Fund of the Natural Science Foundation of Sichuan Province (No. 2023NSFSC1291)
文摘Many magnetohydrodynamic stability analyses require generation of a set of equilibria with a fixed safety factor q-profile while varying other plasma parameters.A neural network(NN)-based approach is investigated that facilitates such a process.Both multilayer perceptron(MLP)-based NN and convolutional neural network(CNN)models are trained to map the q-profile to the plasma current density J-profile,and vice versa,while satisfying the Grad–Shafranov radial force balance constraint.When the initial target models are trained,using a database of semianalytically constructed numerical equilibria,an initial CNN with one convolutional layer is found to perform better than an initial MLP model.In particular,a trained initial CNN model can also predict the q-or J-profile for experimental tokamak equilibria.The performance of both initial target models is further improved by fine-tuning the training database,i.e.by adding realistic experimental equilibria with Gaussian noise.The fine-tuned target models,referred to as fine-tuned MLP and fine-tuned CNN,well reproduce the target q-or J-profile across multiple tokamak devices.As an important application,these NN-based equilibrium profile convertors can be utilized to provide a good initial guess for iterative equilibrium solvers,where the desired input quantity is the safety factor instead of the plasma current density.
文摘A three-fluid equilibrium plasma with bulk plasma and energetic electrons has been observed on the Xuanlong-50(EXL-50) spherical torus, where the energetic electrons play a crucial role in sustaining the plasma current and pressure. In this study, the equilibrium of a multi-fluid plasma was investigated by analyzing the relationship between the external vertical magnetic field(B_(V)),plasma current(I_(p)), the poloidal ratio(β_(p)) and the Shafranov formula. Remarkably, our research demonstrates some validity of the Shafranov formula in the presence of multi-fluid plasma in EXL-50 spherical torus. This finding holds significant importance for future reactors as it allows for differentiation between alpha particles and background plasma. The study of multi-fluid plasma provides a significant reference value for the equilibrium reconstruction of burning plasma involving alpha particles.
基金supported by the program of Fusion Reactor Physics and Digital Tokamak with the CAS‘One-Three-Five’Strategic PlanningNational Natural Science Foundation of China under Grant Nos.11375234,11105175 and 11475219National Magnetic Confinement Fusion Science Program of China under Contract Nos.2015GB101003 and 2015GB110001
文摘Solovev's approach of finding equilibrium solutions was found to be extremely useful for generating a library of linear-superposable equilibria for the purpose of shaping studies.This set of solutions was subsequently expanded to include the vacuum solutions of Zheng,Wootton and Solano,resulting in a set of functions{SOLOVEV_ZWS}that were usually used for all toroidally symmetric plasmas,commonly recognized as being able to accommodate any desired plasma shapes(complete-shaping capability).The possibility of extending the Solovev approach to toroidal equilibria with a general plasma flow is examined theoretically.We found that the only meaningful extension is to plasmas with a pure toroidal rotation and with a constant Mach number.We also show that the simplification ansatz made to the current profiles,which was the basis of the Solovev approach,should be applied more systematically to include an internal boundary condition at the magnetic axis;resulting in a modified and more useful set{SOLOVEV_ZWSm}.Explicit expressions of functions in this set are given for equilibria with a quasi-constant current density profile,with a toroidal flow at a constant Mach number and with specific heat capacity 1.The properties of{SOLOVEV_ZWSm}are studied analytically.Numerical examples of achievable equilibria are demonstrated.Although the shaping capability of the set{SOLOVE_ZWSm}is quite extensive,it nevertheless still does not have complete shaping capability,particularly for plasmas with negative curvature points on the plasma boundary such as the doublets or indented bean shaped tokamaks.
文摘In this paper we present a coupled Finite Element Method–Boundary Element Method(FEM-BEM)approach for the solution of the free-boundary axi-symmetric plasma equilibrium problem.The proposed method,obtained from an improvement of the Hagenow-Lackner coupling method,allows to efficiently model the equilibrium problem in unbounded domains by discretizing only the plasma region;the external conductors can be modelled either as 2D or 3D models,according to the problem of interest.The paper explores different iterative methods for the solution of the nonlinear Grad-Shafranov equation,such as Picard,Newton-Raphson and Newton-Krylov,in order to provide a robust and reliable tool,able to handle large-scale problems(e.g.high resolution equilibria).This method has been implemented in the FRIDA code(FReeboundary Integro-Differential Axisimmetric–https://github.om/matteobonotto/FRIDA),together with a suitable Adaptive Integration Technique(AIT)for the computation of the source term.FRIDA has been successfully tested and validated against experimental data from RFX-mod device,and numerical equilibria of an ITER-like device.
文摘In the reaction of methane and carbon dioxide to C2 hydrocarbons under non-equilibrium plasma, methane conversion was decreased, but selectivity of C2 hydrocarbons was increased when using La2O3/?Al2O3 as catalyst. So the yield of C2 hydrocarbons was higher than using plasma alone. The synergism of La2O3/?Al2O3 and plasma gave methane conversion of 24.9% and C2 yield of 18.1%. The distribution of C2 hydrocarbons changed when Pd- La2O3/?Al2O3 was used as catalyst, the major C2 product was ethylene.
基金National Natural Science Foundation of China(Nos.20576079,20776159)
文摘Catalysis and regeneration efficiency of granular activated carbon (GAC) and activated carbon fiber (ACF) were investigated in a non-equilibrium plasma water treatment reactor with a combination of pulsed streamer discharge and GAC or ACF. The experimental results show that the degradation efficiency of methyl orange (MO) by the combined treatment can increase 22% (for GAC) and 24% (for ACF) respectively compared to pulsed discharge treatment alone, indicating that the combined treatment has a synergetic effect. The MO degradation efficiency by the combined treatment with pulsed discharge and saturated GAC or ACF can increase 12% and 17% respectively compared to pulsed discharge treatment alone. Both GAC and ACF show catalysis and the catalysis of ACF is prominent. Meanwhile, the regeneration of GAC and ACF are realized in this process. When H202 is introduced into the system, the utilization efficiency of ozone and ultraviolet light is improved and the regeneration efficiency of GAC and ACF is also increased.
基金National High-tech Research & Development Plan(863 Projeet)(No.2008AA062317)National Natural Science Foundation of China(No.50578020)
文摘A mini-type of plasma source was studied experimentally. The results showed that the plasma density, which was generated by an atmospheric non-equilibrium plasma source, rises with the increase in driving electric-field and the momentum of gas particles. For a driving electricfield of 56 kV/cm and a gas particles' momentum of 10^9 × 10^-22 g·m/s, the ion density can exceed 10^10/cm^3 while the effective volume of the plasma source is only 2.5 cm^2. This study may help develop a method to generate a minitype plasma source with low energy consumption but high ion concentration. This source can be used in chemical industry, environmental engineering and military applications.
文摘Magnetohydrodynamic (MHD) accelerator is proposed as a next generation propulsion system. It can be used to increase the performance of a propulsion system. The objective of this study is to investigate the performance of MHD accelerator using non-equilibrium air plasma as working gas. In this study, the fundamental performance of MHD accelerator such as flow performance and electrical performance is evaluated at different levels of applied magnetic field using I-D numerical simulation. The numerical simulation is developed based on a set of differential equations with MHD approximation. To solve this set of differential equations the MacCormack scheme is used. A specified channel designed and developed at NASA Marshall Space Flight Centre is used in the numerical simulation. The composition of the simulated air plasma consists of seven species, namely, N2, N, O2, O, NO, NO+, and e-. The performance of the non-equilibrium MHD accelerator is also compared with the equilibrium MHD accelerator.
基金This work was supported by the National Science Foundation of China (No. 30860366) Guizhou Province Municipal Science and Technology Project (No. 2007-6010).
文摘A simple and selective ultra performance liquid chromatography--electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four bioactive ftavonoids (such as orientin and vitexin) in Polygonum orientale. Protein precipitation was used for sample preparation. Equilibrium dialysis technique was applied to determine the plasma protein binding under physiological conditions. The separation was achieved through a Waters C i s column with a mobile phase composed of 0.1% formic acid in acetonitrile and 0.1% aqueous formic acid using step gradient elution at a flow rate of 0.35 mL/min. A Waters ACQUITYTM TQD system was operated under the multiple reaction monitoring (MRM) mode of positive electrospray ionization. All of the recovery, precision, accuracy and stability of the method met the requirements. Good correlations (r 〉 0.99) of the four compounds were found, which suggested that these compounds can be simultaneously determined with acceptable accuracy. Results showed that the plasma protein bindings of the four bioactive flavonoids were in the range of 74-89% over the six concentrations studied. The binding parameters containing protein binding affinity, protein binding dissociation constant, and protein binding site were studied. The maximum ability to bind with protein was also determined in the assay in order to understand the drug-protein binding of each compound better.
基金the National Natural Science Foundation of China(Grant Nos.11105065 and 11275041)the National Basic Research Program of China(Grant Nos.2008CB717801,2008CB787103,2009GB105004,and 2010GB106002)
文摘A code named LARWM with non-ideal magnetohydrodynamic equations in cylindrical model is used to describe the instability in Tokamak plasma surrounded by a conducting wall with finite resistivity. We mainly take three factors related to the shear equilibrium plasma flow into consideration to study the stabilizing effect of the shear flow on the resistive wall modes (RWMs). The three factors are the velocity amplitude of flow, the shear rate of flow on plasma surface, and the inertial energy of equilibrium plasma flow. In addition, a local shear plasma flow is also calculated by the LARWM code. Consequently, it is found that the inertial energy of the shear equilibrium plasma flow has an important role in the stabilization of the RWMs.
基金theNationalNaturalScienceFoundationofChinaUnderGrant (No .199730 18& 196 5 30 0 1)
文摘The equilibrium potential of fluffy dust grains in plasma are calculated for comet P/Halley and comet P/G-Z. It is found that the dust equilibrium potential linearly correlates with the logarithm of electron density. We propose this relationship can also be applied to comet Hale-Bopp.
基金supported by National Natural Science Foundation of China (No. 10725523)
文摘Reconstruction of experimental axisymmetric equilibria is an important part of tokamak data analysis. Fourier expansion is applied to reconstruct the vessel current distribution in EFIT code. Benchmarking and testing calculations are performed to evaluate and validate this algorithm. Two cases for circular and non-circular plasma discharges are presented. Fourier expansion used to fit the eddy current is a robust method and the real time EFIT can be introduced to the plasma control system in the coming campaign.