As a non-destructive testing technology,neutron imaging plays an important role in various fields,including material science,nuclear engineering,and fundamental science.An imaging detector with a neutron-sensitive ima...As a non-destructive testing technology,neutron imaging plays an important role in various fields,including material science,nuclear engineering,and fundamental science.An imaging detector with a neutron-sensitive image intensifier has been developed and demonstrated to achieve good spatial resolution and timing resolution.However,the influence of the working voltage on the performance of the neutron-sensitive imaging intensifier has not been studied.To optimize the performance of the neutron-sensitive image intensifier at different voltages,experiments have been performed at the China Spallation Neutron Source(CSNS)neutron beamline.The change in the light yield and imaging quality with different voltages has been acquired.It is shown that the image quality benefits from the high gain of the microchannel plate(MCP)and the high accelerating electric field between the MCP and the screen.Increasing the accelerating electric field is more effective than increasing the gain of MCPs for the improvement of the imaging quality.Increasing the total gain of the MCP stack can be realized more effectively by improving the gain of the standard MCP than that of the n MCP.These results offer a development direction for image intensifiers in the future.展开更多
Objective: To study the effects on human glioma cell line CHG-5 by ultrasonic microbubble intensifier with survivin antisense oligonucleotides (ASODN) transfection. Methods: Antisense oligonucleotides targeting su...Objective: To study the effects on human glioma cell line CHG-5 by ultrasonic microbubble intensifier with survivin antisense oligonucleotides (ASODN) transfection. Methods: Antisense oligonucleotides targeting survivin mRNA was designed and synthesized. Four regimen groups were designed, group A: survivin antisense oligonucleotides transfected with ultrasonic microbubble intensifier combined with ultrasound irradiation, group B: survivin antisense oligonucleotides transfected with lipofectamine combined with ultrasound irradiation, group C: survivin antisense oligonucelotides with lipofectamine transfection, group D: blank control. The expression changes of surviving protein were measured by immunohistochemical staining and Western blotting, and MTT assay was used to measure the changes of proliferation. Results: Survivin protein expression in group A was decreased significantly in human glioma cell line CHG-5 than other groups(P〈0.05), and the proliferating rate of CHG-5 in group A was also significantly inhibited(P〈0.05). Conclusion: Ultrasonic microbubble intensifier transfection combined with ultrasound irradiation is a promising method in gene transfection effectively and noninvasively.展开更多
Pneumatic-hydraulic transmission has been developed for years. However, its dynamic properties are not good enough for application. In this paper, in order to increase the output characteristics, a late-model air-powe...Pneumatic-hydraulic transmission has been developed for years. However, its dynamic properties are not good enough for application. In this paper, in order to increase the output characteristics, a late-model air-powered vehicle using expansion energy is proposed which can boost energy through a pneumatic-hydraulic transmission. The dynamic characteristics of the air-powered vehicle is modeled and verified by conducting experiment. In addition,the influence of the key parameters of the air-powered vehicle is researched for the optimization of the system performance. Through the results, the author got the conclusion that, firstly, comparison of the results of model and experiment proves the built model to be effective; secondly, input air pressure should be set according to the request of the practical loads, and range of 0.65 to 0.75 MPa can be chosen; thirdly, as a key structure parameter of the airpowered vehicle, ratio of the areas is considered to be set to approximate 8; what’s more, a bigger orifice with a limit will promote the system dynamic characteristic property, and the limit is about 3.5 mm; last but not the least, not too farther position of the rings will increase the quality of output dynamic characteristics. This paper can be a reference for system design of air-powered vehicle and dynamic improvement.展开更多
A new processing technology and the properties of multialkali antimonide photocathodesare described.The technique requires an initial antimony layer to be deposited on a fiber-optic window at asuitable temperature.Aft...A new processing technology and the properties of multialkali antimonide photocathodesare described.The technique requires an initial antimony layer to be deposited on a fiber-optic window at asuitable temperature.After that.the layer is activated by multialkali and antimonide.Thus.the multialkaliphotocathodes named“The Modern Multialkali Photocathode”are obtained.It has been found that aphotocathode thus processed gives a sensitivity of 200 to 300μA/Im for white light at a color temperature of2854K.This paper shows the variation of photosensitivity during processing of a Modern MultialkaliPhotocathode and the variatioon of spectral sensitivity at different wavelengths.The author discusses theresults.gives a supposition of“photoemission center”,and discusses the role of Cs in multialkaliphotocathodes.展开更多
The efficient separation of amphoteric organic compounds from dilute solutions is of great importance in the industrial field. In the present work, the reactive extractions of 4-hydroxypyridine(4-HP) with tributyl pho...The efficient separation of amphoteric organic compounds from dilute solutions is of great importance in the industrial field. In the present work, the reactive extractions of 4-hydroxypyridine(4-HP) with tributyl phosphate(TBP), di(2-ethylhexyl) phosphoric acid(D2EHPA) and TBP + D2EHPA dissolved in 1-octanol were investigated, respectively. The influences of the initial concentrations of TBP, D2EHPA and TBP + D2EHPA on distribution ratio(D) were discussed, as well as the reactive extraction mechanism were proposed. The obvious intensification effect was observed when the mixture of TBP and D2EHPA was used as extractant. The best extraction conditions were found to be of the molar ratio of D2EHPA and TBP at 2:1 and the equilibrium aqueous pH at 3.50-4.50. D values increased with the increase of the total concentration of TBP and D2EHPA in 1-octanol. Especially, the analysis on the extraction mechanisms clearly indicate(i) TBP in 1-octanol shows negligible reactive extraction toward 4-HP,(ii) D2EHPA in 1-octanol exhibits moderate extraction effect by forming 4-HP:D2EHPA(1:1) and 4-HP:2D2EHPA(1:2) type complexes, while(iii) D2EHPA in TBP/1-octanol demonstrates the maximum distribution ratio with the 4-HP:D2EHPA(1:1) type complex domination. The discussion provides new insights on the mechanism and opens a new way for the intensified extraction of amphoteric organic compounds by using the mixture of multiple extractants in the diluent.展开更多
The Chinese government attaches great importance to the legal protection of innovation and intellectual property rights.At the parallel forum named"Rule of Law and Innovation"with the theme of"Intellect...The Chinese government attaches great importance to the legal protection of innovation and intellectual property rights.At the parallel forum named"Rule of Law and Innovation"with the theme of"Intellectual Property and the Development of New Productive Forces"held during the Global Business and Law Conference2024,experts had a heated discussion.Zhang Shaogang,Vice Chairman of the CCPIT,said at the forum,"At present,the momentum of world economic growth is insufficient,and the competition in the frontier areas of the new round of scientific and technological revolution and industrial transformation has intensified.展开更多
基金Project supported by the National Key R&D Program of China (Grant Nos.2023YFC2206502 and 2021YFA1600703)the National Natural Science Foundation of China (Grant Nos.12175254 and 12227810)the Guangdong–Hong Kong–Macao Joint Laboratory for Neutron Scattering Science and Technology。
文摘As a non-destructive testing technology,neutron imaging plays an important role in various fields,including material science,nuclear engineering,and fundamental science.An imaging detector with a neutron-sensitive image intensifier has been developed and demonstrated to achieve good spatial resolution and timing resolution.However,the influence of the working voltage on the performance of the neutron-sensitive imaging intensifier has not been studied.To optimize the performance of the neutron-sensitive image intensifier at different voltages,experiments have been performed at the China Spallation Neutron Source(CSNS)neutron beamline.The change in the light yield and imaging quality with different voltages has been acquired.It is shown that the image quality benefits from the high gain of the microchannel plate(MCP)and the high accelerating electric field between the MCP and the screen.Increasing the accelerating electric field is more effective than increasing the gain of MCPs for the improvement of the imaging quality.Increasing the total gain of the MCP stack can be realized more effectively by improving the gain of the standard MCP than that of the n MCP.These results offer a development direction for image intensifiers in the future.
基金the grants from the National 863 Scientific and Technological Research Projects[National Science Fortune Word No.(2006)501]the Highlight of National Natural Science Foundation of China(No.30430230)
文摘Objective: To study the effects on human glioma cell line CHG-5 by ultrasonic microbubble intensifier with survivin antisense oligonucleotides (ASODN) transfection. Methods: Antisense oligonucleotides targeting survivin mRNA was designed and synthesized. Four regimen groups were designed, group A: survivin antisense oligonucleotides transfected with ultrasonic microbubble intensifier combined with ultrasound irradiation, group B: survivin antisense oligonucleotides transfected with lipofectamine combined with ultrasound irradiation, group C: survivin antisense oligonucelotides with lipofectamine transfection, group D: blank control. The expression changes of surviving protein were measured by immunohistochemical staining and Western blotting, and MTT assay was used to measure the changes of proliferation. Results: Survivin protein expression in group A was decreased significantly in human glioma cell line CHG-5 than other groups(P〈0.05), and the proliferating rate of CHG-5 in group A was also significantly inhibited(P〈0.05). Conclusion: Ultrasonic microbubble intensifier transfection combined with ultrasound irradiation is a promising method in gene transfection effectively and noninvasively.
基金Supported by National Natural Science Foundation of China(Grant No.51375028)
文摘Pneumatic-hydraulic transmission has been developed for years. However, its dynamic properties are not good enough for application. In this paper, in order to increase the output characteristics, a late-model air-powered vehicle using expansion energy is proposed which can boost energy through a pneumatic-hydraulic transmission. The dynamic characteristics of the air-powered vehicle is modeled and verified by conducting experiment. In addition,the influence of the key parameters of the air-powered vehicle is researched for the optimization of the system performance. Through the results, the author got the conclusion that, firstly, comparison of the results of model and experiment proves the built model to be effective; secondly, input air pressure should be set according to the request of the practical loads, and range of 0.65 to 0.75 MPa can be chosen; thirdly, as a key structure parameter of the airpowered vehicle, ratio of the areas is considered to be set to approximate 8; what’s more, a bigger orifice with a limit will promote the system dynamic characteristic property, and the limit is about 3.5 mm; last but not the least, not too farther position of the rings will increase the quality of output dynamic characteristics. This paper can be a reference for system design of air-powered vehicle and dynamic improvement.
文摘A new processing technology and the properties of multialkali antimonide photocathodesare described.The technique requires an initial antimony layer to be deposited on a fiber-optic window at asuitable temperature.After that.the layer is activated by multialkali and antimonide.Thus.the multialkaliphotocathodes named“The Modern Multialkali Photocathode”are obtained.It has been found that aphotocathode thus processed gives a sensitivity of 200 to 300μA/Im for white light at a color temperature of2854K.This paper shows the variation of photosensitivity during processing of a Modern MultialkaliPhotocathode and the variatioon of spectral sensitivity at different wavelengths.The author discusses theresults.gives a supposition of“photoemission center”,and discusses the role of Cs in multialkaliphotocathodes.
基金supported by the Science and Technology Research Project of Henan Province (192102310490 and 212102310505)。
文摘The efficient separation of amphoteric organic compounds from dilute solutions is of great importance in the industrial field. In the present work, the reactive extractions of 4-hydroxypyridine(4-HP) with tributyl phosphate(TBP), di(2-ethylhexyl) phosphoric acid(D2EHPA) and TBP + D2EHPA dissolved in 1-octanol were investigated, respectively. The influences of the initial concentrations of TBP, D2EHPA and TBP + D2EHPA on distribution ratio(D) were discussed, as well as the reactive extraction mechanism were proposed. The obvious intensification effect was observed when the mixture of TBP and D2EHPA was used as extractant. The best extraction conditions were found to be of the molar ratio of D2EHPA and TBP at 2:1 and the equilibrium aqueous pH at 3.50-4.50. D values increased with the increase of the total concentration of TBP and D2EHPA in 1-octanol. Especially, the analysis on the extraction mechanisms clearly indicate(i) TBP in 1-octanol shows negligible reactive extraction toward 4-HP,(ii) D2EHPA in 1-octanol exhibits moderate extraction effect by forming 4-HP:D2EHPA(1:1) and 4-HP:2D2EHPA(1:2) type complexes, while(iii) D2EHPA in TBP/1-octanol demonstrates the maximum distribution ratio with the 4-HP:D2EHPA(1:1) type complex domination. The discussion provides new insights on the mechanism and opens a new way for the intensified extraction of amphoteric organic compounds by using the mixture of multiple extractants in the diluent.
文摘The Chinese government attaches great importance to the legal protection of innovation and intellectual property rights.At the parallel forum named"Rule of Law and Innovation"with the theme of"Intellectual Property and the Development of New Productive Forces"held during the Global Business and Law Conference2024,experts had a heated discussion.Zhang Shaogang,Vice Chairman of the CCPIT,said at the forum,"At present,the momentum of world economic growth is insufficient,and the competition in the frontier areas of the new round of scientific and technological revolution and industrial transformation has intensified.