Irritable bowel syndrome(IBS) is one of the most common gastrointestinal disorders, having a prevalence of 12%-30% in the general population. Most patientswith IBS attribute their symptoms to adverse food reactions. W...Irritable bowel syndrome(IBS) is one of the most common gastrointestinal disorders, having a prevalence of 12%-30% in the general population. Most patientswith IBS attribute their symptoms to adverse food reactions. We review the role of diet in the pathogenesis of IBS and the importance of dietary factors in the management of these patients. The MEDLINE electronic database(1966 to Jan 2015) was searched using the following keywords: "food", "diet", "food allergy", "food hypersensitivity", "food intolerance", "IBS", "epidemiology", "pathogenesis", "pathophysiology", "diagnosis", "treatment". We found 153 eligible papers; 80 were excluded because: not written in English, exclusive biochemical and experimental research, case reports, reviews, and research otherwise not relevant to our specific interest. We selected 73 papers: 43 original papers, 26 reviews and 4 letters to the editor. These papers focused on IBS pathogenesis, the association between IBS and atopy, and between IBS and food allergy, the relationship between IBS and non-celiac wheat sensitivity, the role of diet in IBS. Pending further scientific evidence, a cautious approach is advisable but the concept of food allergy should be included as a possible cause of IBS, and a dietary approach may have a place in the routine clinical management of IBS.展开更多
BACKGROUND Latent autoimmune diabetes in adults(LADA)is a special type of type 1 diabetes mellitus.During the early stages,patients with LADA are treated with oral antidiabetics.However,insulin treatment is still requ...BACKGROUND Latent autoimmune diabetes in adults(LADA)is a special type of type 1 diabetes mellitus.During the early stages,patients with LADA are treated with oral antidiabetics.However,insulin treatment is still required as islet function gradually declines.Once patients have developed insulin allergy,clinical treatment and nursing care become very challenging.CASE SUMMARY Here,we report a case of LADA with insulin-related lipodystrophy,allergy,and exogenous insulin autoimmune syndrome during insulin treatment,thus making it very difficult to effectively control glucose levels with insulin.We attempted subcutaneous injection and an insulin pump to desensitize the patient’s response to insulin,and finally assisted the doctor to select the appropriate insulin treatment for the patient.We describe the management of this patient from a nursing viewpoint.CONCLUSION We summarize the nursing experience of a case with complex insulin allergy requiring desensitization treatment.Our approach is very practical and can be applied to similar patients needing insulin desensitization.展开更多
Kounis syndrome is defined as the coexistence of acute coronary syndromes with situations associated with allergy or hypersensitivity,as well as anaphylactic or anaphylactoid reactions,to a variety of medical conditio...Kounis syndrome is defined as the coexistence of acute coronary syndromes with situations associated with allergy or hypersensitivity,as well as anaphylactic or anaphylactoid reactions,to a variety of medical conditions,environmental and medication exposures.We report a case of Kounis-Zavras syndrome type Ⅰ variant in the setting of aspirin-induced asthma,or the Samter-Beer triad of asthma,nasal polyps and aspirin allergy.When there is a young individual with no predisposing factors of atherosclerosis and apparent coronary lesion,with or without electrocardiography and biochemical markers of infarction,the possibility of Kounis syndrome should be kept in mind.展开更多
1例13岁女性患儿,静脉滴注盐酸万古霉素,1次1 g,1日2次;给药50 min时,出现面色潮红,颈部轻微发红,血压(收缩压/舒张压)降至65/35 mm Hg(1 mm Hg=0.133 kPa),心率增快(133次/min),呼吸频率增快,经皮氧饱和度降至85%;立即停用盐酸万古霉...1例13岁女性患儿,静脉滴注盐酸万古霉素,1次1 g,1日2次;给药50 min时,出现面色潮红,颈部轻微发红,血压(收缩压/舒张压)降至65/35 mm Hg(1 mm Hg=0.133 kPa),心率增快(133次/min),呼吸频率增快,经皮氧饱和度降至85%;立即停用盐酸万古霉素、更换输液通道后,经皮氧饱和度回升至95%及以上,血压恢复正常,面色潮红渐退。该患儿无既往过敏史或相关药品不良反应史,其面色潮红、心率增快及呼吸频率增快等症状与文献报道的1例成人缓慢注射万古霉素后发生红人综合征的案例相似。与过敏反应不同,万古霉素在儿童体内可能诱导组胺释放而致红人综合征。故应实时监测万古霉素血药浓度,注意降低输注速度。展开更多
文摘Irritable bowel syndrome(IBS) is one of the most common gastrointestinal disorders, having a prevalence of 12%-30% in the general population. Most patientswith IBS attribute their symptoms to adverse food reactions. We review the role of diet in the pathogenesis of IBS and the importance of dietary factors in the management of these patients. The MEDLINE electronic database(1966 to Jan 2015) was searched using the following keywords: "food", "diet", "food allergy", "food hypersensitivity", "food intolerance", "IBS", "epidemiology", "pathogenesis", "pathophysiology", "diagnosis", "treatment". We found 153 eligible papers; 80 were excluded because: not written in English, exclusive biochemical and experimental research, case reports, reviews, and research otherwise not relevant to our specific interest. We selected 73 papers: 43 original papers, 26 reviews and 4 letters to the editor. These papers focused on IBS pathogenesis, the association between IBS and atopy, and between IBS and food allergy, the relationship between IBS and non-celiac wheat sensitivity, the role of diet in IBS. Pending further scientific evidence, a cautious approach is advisable but the concept of food allergy should be included as a possible cause of IBS, and a dietary approach may have a place in the routine clinical management of IBS.
文摘BACKGROUND Latent autoimmune diabetes in adults(LADA)is a special type of type 1 diabetes mellitus.During the early stages,patients with LADA are treated with oral antidiabetics.However,insulin treatment is still required as islet function gradually declines.Once patients have developed insulin allergy,clinical treatment and nursing care become very challenging.CASE SUMMARY Here,we report a case of LADA with insulin-related lipodystrophy,allergy,and exogenous insulin autoimmune syndrome during insulin treatment,thus making it very difficult to effectively control glucose levels with insulin.We attempted subcutaneous injection and an insulin pump to desensitize the patient’s response to insulin,and finally assisted the doctor to select the appropriate insulin treatment for the patient.We describe the management of this patient from a nursing viewpoint.CONCLUSION We summarize the nursing experience of a case with complex insulin allergy requiring desensitization treatment.Our approach is very practical and can be applied to similar patients needing insulin desensitization.
文摘Kounis syndrome is defined as the coexistence of acute coronary syndromes with situations associated with allergy or hypersensitivity,as well as anaphylactic or anaphylactoid reactions,to a variety of medical conditions,environmental and medication exposures.We report a case of Kounis-Zavras syndrome type Ⅰ variant in the setting of aspirin-induced asthma,or the Samter-Beer triad of asthma,nasal polyps and aspirin allergy.When there is a young individual with no predisposing factors of atherosclerosis and apparent coronary lesion,with or without electrocardiography and biochemical markers of infarction,the possibility of Kounis syndrome should be kept in mind.
文摘1例13岁女性患儿,静脉滴注盐酸万古霉素,1次1 g,1日2次;给药50 min时,出现面色潮红,颈部轻微发红,血压(收缩压/舒张压)降至65/35 mm Hg(1 mm Hg=0.133 kPa),心率增快(133次/min),呼吸频率增快,经皮氧饱和度降至85%;立即停用盐酸万古霉素、更换输液通道后,经皮氧饱和度回升至95%及以上,血压恢复正常,面色潮红渐退。该患儿无既往过敏史或相关药品不良反应史,其面色潮红、心率增快及呼吸频率增快等症状与文献报道的1例成人缓慢注射万古霉素后发生红人综合征的案例相似。与过敏反应不同,万古霉素在儿童体内可能诱导组胺释放而致红人综合征。故应实时监测万古霉素血药浓度,注意降低输注速度。
