Herbal plants act as a significant source for discovering new compounds with potential therapeutic activities.Polyalthia longifolia,which is commonly known as an Indian mast tree,has various pharmacological properties...Herbal plants act as a significant source for discovering new compounds with potential therapeutic activities.Polyalthia longifolia,which is commonly known as an Indian mast tree,has various pharmacological properties,such as an anticancer,ulcer protective,hypoglycemic,hypotensive,a corrosion inhibitor,a bio-adsorbent,and few more.Moreover,it is known as false ashoka owing to its close resemblance with Saraca indica(ashoka tree).Various compounds have been reported from the extract of some parts of the plant,such as leaves,bark,root,and seeds.These extracts possess an ability to treat a number of human ailments,such as fever,ulcer,skin diseases,helminthiasis,and cardiac problems.Studies performed on the leave extract shows evidence that some compounds cause cell death in various cancer cell lines.The plant also has some biological applications,such as antibacterial,antiviral,and antimicrobial,which makes it clinically significant and useful.This review is an effort to explore and gather plant information in an organized manner.It reveals detailed information about the propagation,synonyms,vernaculars,varieties of plant,medicinal significance,ecology and distribution,botanical and ethnobotanical description,phytochemical constituents,and pharmacological activity of the plant.展开更多
Objective:To explore antiulcer and antimicrobial properties of methanolic extract of Polyalthia longifolia var.pendula.Methods:Gastroprotective potential of Polyalthia longifolia was studied on ethanol and ethanol/HCl...Objective:To explore antiulcer and antimicrobial properties of methanolic extract of Polyalthia longifolia var.pendula.Methods:Gastroprotective potential of Polyalthia longifolia was studied on ethanol and ethanol/HCl induced ulcers at 2 different doses(270 and 540 mg/kg/body weight). Antimicrobial efficacy of Polyalthia longifolia(25 mg/mL) was also studied against six gram positive,seven gram negative bacteria and five fungi by agar well diffusion method.Minimum inhibitory concentration was determined by agar well diffusion method in two fold serial dilution, in the range of 97-25 000μg/mL.Results:The reduction of ulcer index in Polyalthia longifolia treated animals was found to be statistically significant with respect to control animals.The Polyalthia longifolia exhibited ulcer protection activity in dose dependent manner and was also better than the standard.In antimicrobial activity,gram positive bacteria were more susceptible to Polyalthia longifolia than gram negative bacteria and fungal strains.Conclusions:Results obtained confirm the antiulcer and antimicrobial potential of the Polyalthia longifolia.展开更多
The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which we...The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. The antibacterial activity was more pronounced against gram positive bacterial and fungal strains. Poor activity was shown against gram negative bacterial strains studied.展开更多
文摘Herbal plants act as a significant source for discovering new compounds with potential therapeutic activities.Polyalthia longifolia,which is commonly known as an Indian mast tree,has various pharmacological properties,such as an anticancer,ulcer protective,hypoglycemic,hypotensive,a corrosion inhibitor,a bio-adsorbent,and few more.Moreover,it is known as false ashoka owing to its close resemblance with Saraca indica(ashoka tree).Various compounds have been reported from the extract of some parts of the plant,such as leaves,bark,root,and seeds.These extracts possess an ability to treat a number of human ailments,such as fever,ulcer,skin diseases,helminthiasis,and cardiac problems.Studies performed on the leave extract shows evidence that some compounds cause cell death in various cancer cell lines.The plant also has some biological applications,such as antibacterial,antiviral,and antimicrobial,which makes it clinically significant and useful.This review is an effort to explore and gather plant information in an organized manner.It reveals detailed information about the propagation,synonyms,vernaculars,varieties of plant,medicinal significance,ecology and distribution,botanical and ethnobotanical description,phytochemical constituents,and pharmacological activity of the plant.
基金University Grants Commission,New Delhi,India for providing financial support as Junior Research Fellow
文摘Objective:To explore antiulcer and antimicrobial properties of methanolic extract of Polyalthia longifolia var.pendula.Methods:Gastroprotective potential of Polyalthia longifolia was studied on ethanol and ethanol/HCl induced ulcers at 2 different doses(270 and 540 mg/kg/body weight). Antimicrobial efficacy of Polyalthia longifolia(25 mg/mL) was also studied against six gram positive,seven gram negative bacteria and five fungi by agar well diffusion method.Minimum inhibitory concentration was determined by agar well diffusion method in two fold serial dilution, in the range of 97-25 000μg/mL.Results:The reduction of ulcer index in Polyalthia longifolia treated animals was found to be statistically significant with respect to control animals.The Polyalthia longifolia exhibited ulcer protection activity in dose dependent manner and was also better than the standard.In antimicrobial activity,gram positive bacteria were more susceptible to Polyalthia longifolia than gram negative bacteria and fungal strains.Conclusions:Results obtained confirm the antiulcer and antimicrobial potential of the Polyalthia longifolia.
文摘The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. The antibacterial activity was more pronounced against gram positive bacterial and fungal strains. Poor activity was shown against gram negative bacterial strains studied.
