Out-of-autoclave(OoA) processing has the advantages of low cost,light weight and environmental protection,and has become a hot spot in the field of composite materials worldwide. This paper investigates the applicatio...Out-of-autoclave(OoA) processing has the advantages of low cost,light weight and environmental protection,and has become a hot spot in the field of composite materials worldwide. This paper investigates the application of OoA processing in the gondola of the AS700 civil manned airship. The production cost of gondolas is reduced by selecting low cost materials such as glass fiber,PVC foam and OoA processing. The porosity of parts is reduced and controlled at about 2% by optimizing the edge breathing of prepreg during curing. The maximum tensile strain of the glass fiber is 4 593 με;its maximum compressive strain is 3 680 με;and its maximum shear strain is4 884 με. The maximum Von Mises stress of the foam is 0.70 MPa. These settings all meet the margin requirement of safety. Finally,the ultimate load test of the gondola is carried out to verify the safety of the gondola structure. Our study presents critical parameters for the gondola design,including load,structure,strength,and manufacturing process test,and provides certain references for the design of similar products.展开更多
In this paper controlled porosity osmotic pump tablets(CPOPT)for salvianolic acid(SA)were prepared and optimized with experimental design methods including an artificial neutral network(ANN)method.Three causal factors...In this paper controlled porosity osmotic pump tablets(CPOPT)for salvianolic acid(SA)were prepared and optimized with experimental design methods including an artificial neutral network(ANN)method.Three causal factors,i.e.,drug,osmotic pressure promoting agent rate,PEG400 content in coating solution and coating weight,were evaluated based on their effects on drug release rate.The linear correlation coefficient of the accumulative amount of drug release and the time of 12 h,r(Y_(1)),and the sum of the absolute value between measured and projected values,Y_(2),were used as outputs to optimize the formulation.The weight expression Y=(1-Y_(1))^(2)+Y_(2)^(2) was used in the calculation.Furthermore,the ANN and uniform design gave similar optimization results,but ANN projected the outputs better than the uniform design.This paper showed that the release rate of salvianolic acid B and that of the total salvianolic acid was consistent in the optimized formulation.展开更多
There are significant effects of process parameters on internal qualities of bloom, and these process parameters are as follows. position and reduction amount, reduction distribution, reduction rate, and so on. Develo...There are significant effects of process parameters on internal qualities of bloom, and these process parameters are as follows. position and reduction amount, reduction distribution, reduction rate, and so on. Developing a control model is the key to apply soft reduction technology successfully. As the research object, 360 mm ×450 mm bloom caster in PISCO (Panzhihua Iron and Steel Co. ) has been studied, and the research method for control model of dynamic soft reduction has been proposed. On the basis of solidification and heat transfer model, the position of soft reduction and reduction distribution of each frame are determined according to the bloom temperature distribution and solid fraction in bloom center calculated. Production practice shows that the ratio of center porosity which is less than or equal to 1.0, increased to 97.27%, ratio of central segregation which is less than or equal to 0.5, increased to 80.91%, and ratio of central carbon segregation index which is more than or equal to 1.10, decreased to 4% with the applying model of dynamic soft reduction.展开更多
Electrospinning is one of the most effective approaches to fabricate tissue-engineered scaffolds composed of nano-to sub-microscale fibers that simulate a native extracellular matrix.However,one major concern about el...Electrospinning is one of the most effective approaches to fabricate tissue-engineered scaffolds composed of nano-to sub-microscale fibers that simulate a native extracellular matrix.However,one major concern about electrospun scaffolds for tissue repair and regeneration is that their small pores defined by densely compacted fibers markedly hinder cell infiltration and tissue ingrowth.To address this problem,researchers have developed and investigated various methods of manipulating scaffold structures to increase pore size or loosen the scaffold.These methods involve the use of physical treatments,such as salt leaching,gas foaming and custom-made collectors,and combined techniques to obtain electrospun scaffolds with loose fibrous structures and large pores.This article provides a summary of these motivating electrospinning techniques to enhance cell infiltration of electrospun scaffolds,which may inspire new electrospinning techniques and their new biomedical applications.展开更多
Electrohydrodynamic(EHD)3D printing of ca rbon-based materials in the form of orderly networks can have various applications.In this work,microscale carbon/nickel(C-Ni)composite electrodes with controlled porosity hav...Electrohydrodynamic(EHD)3D printing of ca rbon-based materials in the form of orderly networks can have various applications.In this work,microscale carbon/nickel(C-Ni)composite electrodes with controlled porosity have been utilized in electrochemical energy storage of supercapacitors.Polyacrylonitrile(PAN)was chosen as the basic material for its excellent carbonization performance and EHD printing property.Nickel nitrate(Ni(NO_(3))_(2))was incorporated to form Ni nanoparticles which can improve the conductivity and the capacitance performance of the electrode.Well-aligned PAN-Ni(NO_(3))_(2) composite structures have been fabricated and carbonized as C-Ni electrodes with the typical diameter of 9.2±2.1μm.The porosity of the as-prepared C-Ni electrode can be controlled during the EHD process.Electrochemical results show the C-Ni network electrode has achieved a 2.3 times higher areal specific capacitance and 1.7 times higher mass specific capacitance than those of a spin-coated electrode.As such,this process offers a facile and scalable strategy for the fabrication of orderly carbon-based conductive structures for various applications such as energy storage devices and printable electronics.展开更多
基金supported in part by China Special Vehicle Research Institute and the Priority Academic Program Development of Jiangsu Higher Education Institutions。
文摘Out-of-autoclave(OoA) processing has the advantages of low cost,light weight and environmental protection,and has become a hot spot in the field of composite materials worldwide. This paper investigates the application of OoA processing in the gondola of the AS700 civil manned airship. The production cost of gondolas is reduced by selecting low cost materials such as glass fiber,PVC foam and OoA processing. The porosity of parts is reduced and controlled at about 2% by optimizing the edge breathing of prepreg during curing. The maximum tensile strain of the glass fiber is 4 593 με;its maximum compressive strain is 3 680 με;and its maximum shear strain is4 884 με. The maximum Von Mises stress of the foam is 0.70 MPa. These settings all meet the margin requirement of safety. Finally,the ultimate load test of the gondola is carried out to verify the safety of the gondola structure. Our study presents critical parameters for the gondola design,including load,structure,strength,and manufacturing process test,and provides certain references for the design of similar products.
文摘In this paper controlled porosity osmotic pump tablets(CPOPT)for salvianolic acid(SA)were prepared and optimized with experimental design methods including an artificial neutral network(ANN)method.Three causal factors,i.e.,drug,osmotic pressure promoting agent rate,PEG400 content in coating solution and coating weight,were evaluated based on their effects on drug release rate.The linear correlation coefficient of the accumulative amount of drug release and the time of 12 h,r(Y_(1)),and the sum of the absolute value between measured and projected values,Y_(2),were used as outputs to optimize the formulation.The weight expression Y=(1-Y_(1))^(2)+Y_(2)^(2) was used in the calculation.Furthermore,the ANN and uniform design gave similar optimization results,but ANN projected the outputs better than the uniform design.This paper showed that the release rate of salvianolic acid B and that of the total salvianolic acid was consistent in the optimized formulation.
文摘There are significant effects of process parameters on internal qualities of bloom, and these process parameters are as follows. position and reduction amount, reduction distribution, reduction rate, and so on. Developing a control model is the key to apply soft reduction technology successfully. As the research object, 360 mm ×450 mm bloom caster in PISCO (Panzhihua Iron and Steel Co. ) has been studied, and the research method for control model of dynamic soft reduction has been proposed. On the basis of solidification and heat transfer model, the position of soft reduction and reduction distribution of each frame are determined according to the bloom temperature distribution and solid fraction in bloom center calculated. Production practice shows that the ratio of center porosity which is less than or equal to 1.0, increased to 97.27%, ratio of central segregation which is less than or equal to 0.5, increased to 80.91%, and ratio of central carbon segregation index which is more than or equal to 1.10, decreased to 4% with the applying model of dynamic soft reduction.
基金We greatly thank financial supports from the American Heart Association(Beginning Grant-in-Aid,#14BGIA20510066)the National Scientific Foundation(CAREER,#1554835)in the United States of America.
文摘Electrospinning is one of the most effective approaches to fabricate tissue-engineered scaffolds composed of nano-to sub-microscale fibers that simulate a native extracellular matrix.However,one major concern about electrospun scaffolds for tissue repair and regeneration is that their small pores defined by densely compacted fibers markedly hinder cell infiltration and tissue ingrowth.To address this problem,researchers have developed and investigated various methods of manipulating scaffold structures to increase pore size or loosen the scaffold.These methods involve the use of physical treatments,such as salt leaching,gas foaming and custom-made collectors,and combined techniques to obtain electrospun scaffolds with loose fibrous structures and large pores.This article provides a summary of these motivating electrospinning techniques to enhance cell infiltration of electrospun scaffolds,which may inspire new electrospinning techniques and their new biomedical applications.
基金supported in part by Berkeley Sensor and Actuator Center&Berkeley Biomolecular Nanotechnology Centerfinancially supported by the National Key Research and Design Program of China(No.2018YFA0703000)+3 种基金the National Natural Science Foundation of China(Nos.51675412,51422508)the Key Research Project of Shaanxi Province(No.2020GXLH-Y-021)The Youth Innovation Team of Shaanxi Universities and the Fundamental Research Funds for the Central Universitiesfinancial support from China Scholarship Council。
文摘Electrohydrodynamic(EHD)3D printing of ca rbon-based materials in the form of orderly networks can have various applications.In this work,microscale carbon/nickel(C-Ni)composite electrodes with controlled porosity have been utilized in electrochemical energy storage of supercapacitors.Polyacrylonitrile(PAN)was chosen as the basic material for its excellent carbonization performance and EHD printing property.Nickel nitrate(Ni(NO_(3))_(2))was incorporated to form Ni nanoparticles which can improve the conductivity and the capacitance performance of the electrode.Well-aligned PAN-Ni(NO_(3))_(2) composite structures have been fabricated and carbonized as C-Ni electrodes with the typical diameter of 9.2±2.1μm.The porosity of the as-prepared C-Ni electrode can be controlled during the EHD process.Electrochemical results show the C-Ni network electrode has achieved a 2.3 times higher areal specific capacitance and 1.7 times higher mass specific capacitance than those of a spin-coated electrode.As such,this process offers a facile and scalable strategy for the fabrication of orderly carbon-based conductive structures for various applications such as energy storage devices and printable electronics.