AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 ...AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 to December 1998, CTAP and CTHA were performed in 12patients with MLC, which were not detect ed byconventional CT examinations. After CTHA, 3 mL-- 5 mL mixture of lipiodol, doxorubic in andmitomycin C were injected into hepatic arterythrough the catheter, and then followed up by CTthree or four weeks later (Lipiodol CT LP-CT).RESULTS A total of 22 micro--tumors (0 .2 cm 0.6 cm in diameter ) were detected in 12patients, which manifested as small perfusiondefects in CTAP and small round enhancement inCTHA. The rate of detectability of CTAP andCTHA was 68.2% (15/ 22) and 77.3% (17/ 22)respectively, and the rate of the simultaneoususe of both procedures reached 86. 4% (19/ 22 ).All micro--tumors were demonstrated as punctatelipiodol deposit fool in LP--CT. After LP--CT, theelevated serum level of Q-fetoprotein (AFP)dropped to the normal level in all patients.CONCLUSION The CTAP and CTHA are the mostsensitive imaging methods for detecting microIiver cancer. Confirmed by the change of theelevated serum AFP level and lipiodol depositfool in LP-CT, small perfusion defects in CTAPand punctate enhancement in CTHA may suggestmicro--liver cancer.展开更多
Objective To introduce computed tomography via percutaneous splenoportography (CTSP), a new method for determining hepatic diseases Methods Ten hybrid dogs and 31 patients with primary hepatic cancer (PHC) were in...Objective To introduce computed tomography via percutaneous splenoportography (CTSP), a new method for determining hepatic diseases Methods Ten hybrid dogs and 31 patients with primary hepatic cancer (PHC) were included in the study Each dog was examined by CT, computed tomography via arterial portography (CTAP), and CTSP to compare the enhanced density of the liver The 31 patients were examined by CTSP and the appearanec of PHC was compared with their pathological results to evaluate the diagnostic significance of CTSP Results The animal experiment showed that both CTAP and CTSP could obviously enhance the density of the liver ( P <0 01), but no significant difference was observed in the enhanced densities between the two methods ( P >0 05) On the CTSP images of the 31 patients, the density of the livers was increased to 168-192?Hu, whereas the density of the cancers was as low as that on the images of CT scans (<58?Hu) The CTSP findings were consistent with the surgical ones from space occupying lesions The diagnostic value of CTSP was obviously superior to that of general enhanced CT However, it was difficult for CTSP to show nodules less than 1?cm in size located on the surface of the liver or the hepatic portal zone Conclusions Like CTAP, CTSP is also a sensitive method for showing occupant in the liver But the equipments and the procedures are simpler for CTSP than for CTAP CTSP is an alternative procedure in clinical practice展开更多
基金Supported by“9.5”National Major Project of National Cammittee of Sciences and Technology,No.96-907-03-02.
文摘AIM To recognize the characteristic findings of micrQliver cancer (MLC) and to evaluate the effect of CT arterial portography (CTAP) and CT hepatic arteriography (CTHA) in diagnosis of MLC. METHODS Between April 1996 to December 1998, CTAP and CTHA were performed in 12patients with MLC, which were not detect ed byconventional CT examinations. After CTHA, 3 mL-- 5 mL mixture of lipiodol, doxorubic in andmitomycin C were injected into hepatic arterythrough the catheter, and then followed up by CTthree or four weeks later (Lipiodol CT LP-CT).RESULTS A total of 22 micro--tumors (0 .2 cm 0.6 cm in diameter ) were detected in 12patients, which manifested as small perfusiondefects in CTAP and small round enhancement inCTHA. The rate of detectability of CTAP andCTHA was 68.2% (15/ 22) and 77.3% (17/ 22)respectively, and the rate of the simultaneoususe of both procedures reached 86. 4% (19/ 22 ).All micro--tumors were demonstrated as punctatelipiodol deposit fool in LP--CT. After LP--CT, theelevated serum level of Q-fetoprotein (AFP)dropped to the normal level in all patients.CONCLUSION The CTAP and CTHA are the mostsensitive imaging methods for detecting microIiver cancer. Confirmed by the change of theelevated serum AFP level and lipiodol depositfool in LP-CT, small perfusion defects in CTAPand punctate enhancement in CTHA may suggestmicro--liver cancer.
文摘Objective To introduce computed tomography via percutaneous splenoportography (CTSP), a new method for determining hepatic diseases Methods Ten hybrid dogs and 31 patients with primary hepatic cancer (PHC) were included in the study Each dog was examined by CT, computed tomography via arterial portography (CTAP), and CTSP to compare the enhanced density of the liver The 31 patients were examined by CTSP and the appearanec of PHC was compared with their pathological results to evaluate the diagnostic significance of CTSP Results The animal experiment showed that both CTAP and CTSP could obviously enhance the density of the liver ( P <0 01), but no significant difference was observed in the enhanced densities between the two methods ( P >0 05) On the CTSP images of the 31 patients, the density of the livers was increased to 168-192?Hu, whereas the density of the cancers was as low as that on the images of CT scans (<58?Hu) The CTSP findings were consistent with the surgical ones from space occupying lesions The diagnostic value of CTSP was obviously superior to that of general enhanced CT However, it was difficult for CTSP to show nodules less than 1?cm in size located on the surface of the liver or the hepatic portal zone Conclusions Like CTAP, CTSP is also a sensitive method for showing occupant in the liver But the equipments and the procedures are simpler for CTSP than for CTAP CTSP is an alternative procedure in clinical practice
