BACKGROUND The impact caused by the coronavirus disease 2019(COVID-19)on the Portuguese population has been addressed in areas such as clinical manifestations,frequent comorbidities,and alterations in consumption habi...BACKGROUND The impact caused by the coronavirus disease 2019(COVID-19)on the Portuguese population has been addressed in areas such as clinical manifestations,frequent comorbidities,and alterations in consumption habits.However,comorbidities like liver conditions and changes concerning the Portuguese population's access to healthcare-related services have received less attention.AIM To(1)Review the impact of COVID-19 on the healthcare system;(2)examine the relationship between liver diseases and COVID-19 in infected individuals;and(3)investigate the situation in the Portuguese population concerning these topics.METHODS For our purposes,we conducted a literature review using specific keywords.RESULTS COVID-19 is frequently associated with liver damage.However,liver injury in COVID-19 individuals is a multifactor-mediated effect.Therefore,it remains unclear whether changes in liver laboratory tests are associated with a worse prognosis in Portuguese individuals with COVID-19.CONCLUSION COVID-19 has impacted healthcare systems in Portugal and other countries;the combination of COVID-19 with liver injury is common.Previous liver damage may represent a risk factor that worsens the prognosis in individuals with COVID-19.展开更多
this study provided the strong evidence that L2 learner's development patterns in syntactic structure is very similar to the pattern of L1 learners.L2 and L1 learner pass the similar gradual route to get the TL ne...this study provided the strong evidence that L2 learner's development patterns in syntactic structure is very similar to the pattern of L1 learners.L2 and L1 learner pass the similar gradual route to get the TL negative structure.But L2 learners' acquisitional sequences are not completely rigid.Individual learners may be interfered by other social or psychological factors en route and they may take longer than two years and some never travel the whole distance.展开更多
Weight/length relationships, condition factor, gonadosomatic and hepatosomatic indices, conversion factor for gutted to total weight and spawning season of hake in the Portuguese Coast (36.92 to 42.22 degrees latitude...Weight/length relationships, condition factor, gonadosomatic and hepatosomatic indices, conversion factor for gutted to total weight and spawning season of hake in the Portuguese Coast (36.92 to 42.22 degrees latitude N;9.61 to 6.07 degrees longitude W) were investigated for the first time, aiming to fill the lack of information on the biology of hake of the Portuguese waters. Data were obtained from commercial samples collected between 2005 and 2010 and pooled by month. Sex ratio observed in fish below 40 cmwas close to 1:1;females were always dominant above50 cmlength. All the parameters were analysed by month and by sex and by combined sexes. The relationships obtained for combined sexes for the entire period concerning the growth in length and weight were: total length-total weight =0.0038L3.172, total length-gutted weight =0.0052L3.059. The relationship total weight-gutted weight was Wt = 15.8112 + 0.8480Wg and the conversion factor was of 1.1524. The growth rate is similar for both sexes but different when based on total weight or gutted weight. The analysis of the condition factor, gonadosomatic index, hepatosomatic index and the monthly distribution of the maturity stages seem to indicate that hake from thePortugueseCoasthas a long spawning season, with three spawning peaks in March, May and August but the start of the spawning season seems independent of the fish length.展开更多
The Constitution in Chinese Medicine Questionnaire [CCMQ] organizes 9 body constitutions according to Traditional Chinese Medicine [TCM]. The translation was realized by a Medical Doctor [MD] specialized in TCM and th...The Constitution in Chinese Medicine Questionnaire [CCMQ] organizes 9 body constitutions according to Traditional Chinese Medicine [TCM]. The translation was realized by a Medical Doctor [MD] specialized in TCM and the back translation by an english-speaking MD. Comprehensibility assessment was performed (N = 40, main scores ranged from 4.20 to 4.95). On the test-retest reliability Cronbach’s alpha was 0.920 in the first application and 0.943 in the second, the intraclass correlation scores ranged between good and excellent (0.6 - >0.80). The results show that the adaptation of the CCMQ is valid and ready to be used.展开更多
At the invitation of the Chinese Associa-tion for Intermational Understanding,a may-ors'delegation of the Portuguese Socialists Party,composed of eight members and headed by Mr.Ferraz de Abredu,former President of...At the invitation of the Chinese Associa-tion for Intermational Understanding,a may-ors'delegation of the Portuguese Socialists Party,composed of eight members and headed by Mr.Ferraz de Abredu,former President of the Portuguese Socialist Party&.Former Dep-uty-Speaker of the Parliament of the Republic of Portugal,visited China during the 2nd to the l0th June 1996.The delegation was met re-spectively by Mr.Wei Jianxing,Member of the Political Bureau of the CPC Central Commit-tee&.member of the CPC Secretariat,and Mr.Wan Guoquan,Vice-Chairman of the CPPCC National Committee and Vice President of the CAFIU.展开更多
This study presents a pictorial analysis of Portuguese advertisements from a visual semiotic perspective,particularly the symbolic attributive and suggestiveprocesses.Aiming toelucidate the relationship between genrea...This study presents a pictorial analysis of Portuguese advertisements from a visual semiotic perspective,particularly the symbolic attributive and suggestiveprocesses.Aiming toelucidate the relationship between genreand gender,the study explored advertising genre,masculinity in advertisements,and the antithesis of man as primary theoretical concerns.The data consisted of five pictures from Portuguese advertisements.The analysis suggests that advertisements are a textual arena where not only genre but also gender is constructed and modified in collaboration.The image of the antithesis of man coexisting with the one of normative masculinity in the five Portuguese advertisements indicates that genre and gender are mutually and simultaneously fluid,with their boundary often blurred.That advertisements are often prone to changes in their function to attract customers implies new and evolving presentation forms of genre and gender.The combination of new and conventional images of masculinity,as shown in the analysis,impacts social and linguistic practices,particularly the fact that traditional norms of defining genre and gender,despite their resemblant quality,might be occasionally challenged or reconstructed inlate-modern culture.展开更多
Josefa Figueira de Ayala de Cabrera D’Óbidos was a renowned Baroque painter from Portugal who lived between 1630 and 1684.She was an accomplished artist and one of the most notable female artists of her time.Her...Josefa Figueira de Ayala de Cabrera D’Óbidos was a renowned Baroque painter from Portugal who lived between 1630 and 1684.She was an accomplished artist and one of the most notable female artists of her time.Her works included both secular and religious themes,and she used a variety of mediums with great skill.Despite having different surnames,she signed her paintings under Josepha emÓbidos.This article concentrates on the artist’s landscapes(vedute)and integrated still-life paintings(bodegones).It delves into her capacity to depict the changing seasons through these themes.Josefa expertly combined Baroque tenebrism and illusionism with her love of Nature,highlighting both the physical and spiritual aspects of the natural world.Her paintings are visually captivating,with beautiful colors and intricate details.She incorporated emblematic and mystical symbolism,which added to their spiritual significance in portraying the flora and fauna of her homeland.展开更多
Necropsies and extensive histological evaluation for clinical and sub-clinical disease of approximately three hundred Portuguese Water dogs are available as part of an ongoing study to assess their state of health at ...Necropsies and extensive histological evaluation for clinical and sub-clinical disease of approximately three hundred Portuguese Water dogs are available as part of an ongoing study to assess their state of health at the end of life. Throughout life these dogs enjoyed a variety of lifestyles and environments. Here we carry out retrospective quantitative assessments of life-time dietary input and physical activity for each dog. To do this, collagens from skull vault bone and from dentine have been analyzed for ratios of stable isotopes to determine differences in diet that individual dogs experienced during late or early life respectively. Robustness of skull bone (weight/unit of skull size) was used as a relative indicator of the amount of physical activity experienced during a dog’s lifetime. These environmental parameters were correlated with the frequency and severity of specific disease processes determined at necropsy. Both measures were shown to exert significant low-level展开更多
The aim of this work was to evaluate the effect of different olive leaf extracts (OLE) from different leaf growing stages on human carcinoma cell lines. OLE were tested in human carcinoma cell lines in vitro and cells...The aim of this work was to evaluate the effect of different olive leaf extracts (OLE) from different leaf growing stages on human carcinoma cell lines. OLE were tested in human carcinoma cell lines in vitro and cells were plated in 96-microtiter culture plates for each OLE concentration. Fresh (F) and freeze-dried (FD) leaves exhibited phenolic compounds in the range of 2.09 ± 0.10 to 8.44 ± 0.64 and 7.72 ± 0.56 to 24.65 ± 1.9 mg gallic acid equivalents/g leaves, respectively. OLE from several Portuguese olive tree cultivars were found to inhibit the growth of human carcinoma cell lines in a range of 2.09 - 8.44 μg phenolic compound/well (209 - 844 μg/ml) and 0.07 - 2.40 μg phenolic compounds/well (7 - 240 μg/ml) for fresh and freeze-dried leaves, respectively. Young (Y) leaves have revealed the highest cell growth inhibition ranging from about 95% for Cobran?osa, followed by 90% for Cobran?osa, 90% for Arbequina and 75% for Arbequina for cell lines A549, HeLa, A431 and OE21, respectively. The lowest cell growth inhibition (35%) was observed for Galega (Y) leaf extract on cell line A549. However, FD samples exhibited a distinctive pattern since cell growth inhibition was highest at highest extract dilution tested, for A431 (Galega Y) followed by A549 (Cobran?osa Y) with cell inhibition of 75% and 70%, respectively. The data presented in this work strongly suggest that OLEs inhibit the growth of human carcinoma cell lines.展开更多
L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils we...L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.展开更多
Continuous changes in vehicle technology,road condition,traffic compositions initiate the change or updating of road users’cost models.So that it needs to practice a continuous revision or update periodically f...Continuous changes in vehicle technology,road condition,traffic compositions initiate the change or updating of road users’cost models.So that it needs to practice a continuous revision or update periodically for realistic estimation of costs and benefits.This paper presented the relationship and comparison between road users’cost along Addis Ababa-Adama newly constructed expressway using the Highway Development and Management(HDM-4)Software and manually using formulations developed in the Portuguese model.The method started with data collection.All input data were collected from primary and secondary sources.The primary data utilized an interview,and secondary data were sourced out from pertinent documents,both published and unpublished.More data were gathered that related to vehicles.The vehicles using the road are classified based on the manual from the Ethiopian Road Authority as cars,utilities,small bus,large bus,small truck,medium truck,heavy truck,and truck trailer.The collected data have been input into the HDM-4 interface;the output of the analysis was vehicle operating costs,travel time,and road users’cost as a summation.Using manual technique and HDM-4 Software,Birr 128.62/km/vehicle and Birr 139.23/km/vehicle,respectively,were found from road users’costs analysis.The result shows the difference of Birr 10.61.Also,the correlation coefficient of 0.75 is determined,which shows that the two results of road users’costs are highly related.As a result,the study reveals that the application of HDM-4 Software and the manual technique formulations from the Portuguese model can be adopted interchangeably to calculate Road Users’Cost of road sections in Ethiopia.Hence,the study results are expected to be an eye-opener for a future similar project by the concerned agencies.展开更多
文摘BACKGROUND The impact caused by the coronavirus disease 2019(COVID-19)on the Portuguese population has been addressed in areas such as clinical manifestations,frequent comorbidities,and alterations in consumption habits.However,comorbidities like liver conditions and changes concerning the Portuguese population's access to healthcare-related services have received less attention.AIM To(1)Review the impact of COVID-19 on the healthcare system;(2)examine the relationship between liver diseases and COVID-19 in infected individuals;and(3)investigate the situation in the Portuguese population concerning these topics.METHODS For our purposes,we conducted a literature review using specific keywords.RESULTS COVID-19 is frequently associated with liver damage.However,liver injury in COVID-19 individuals is a multifactor-mediated effect.Therefore,it remains unclear whether changes in liver laboratory tests are associated with a worse prognosis in Portuguese individuals with COVID-19.CONCLUSION COVID-19 has impacted healthcare systems in Portugal and other countries;the combination of COVID-19 with liver injury is common.Previous liver damage may represent a risk factor that worsens the prognosis in individuals with COVID-19.
文摘this study provided the strong evidence that L2 learner's development patterns in syntactic structure is very similar to the pattern of L1 learners.L2 and L1 learner pass the similar gradual route to get the TL negative structure.But L2 learners' acquisitional sequences are not completely rigid.Individual learners may be interfered by other social or psychological factors en route and they may take longer than two years and some never travel the whole distance.
文摘Weight/length relationships, condition factor, gonadosomatic and hepatosomatic indices, conversion factor for gutted to total weight and spawning season of hake in the Portuguese Coast (36.92 to 42.22 degrees latitude N;9.61 to 6.07 degrees longitude W) were investigated for the first time, aiming to fill the lack of information on the biology of hake of the Portuguese waters. Data were obtained from commercial samples collected between 2005 and 2010 and pooled by month. Sex ratio observed in fish below 40 cmwas close to 1:1;females were always dominant above50 cmlength. All the parameters were analysed by month and by sex and by combined sexes. The relationships obtained for combined sexes for the entire period concerning the growth in length and weight were: total length-total weight =0.0038L3.172, total length-gutted weight =0.0052L3.059. The relationship total weight-gutted weight was Wt = 15.8112 + 0.8480Wg and the conversion factor was of 1.1524. The growth rate is similar for both sexes but different when based on total weight or gutted weight. The analysis of the condition factor, gonadosomatic index, hepatosomatic index and the monthly distribution of the maturity stages seem to indicate that hake from thePortugueseCoasthas a long spawning season, with three spawning peaks in March, May and August but the start of the spawning season seems independent of the fish length.
文摘The Constitution in Chinese Medicine Questionnaire [CCMQ] organizes 9 body constitutions according to Traditional Chinese Medicine [TCM]. The translation was realized by a Medical Doctor [MD] specialized in TCM and the back translation by an english-speaking MD. Comprehensibility assessment was performed (N = 40, main scores ranged from 4.20 to 4.95). On the test-retest reliability Cronbach’s alpha was 0.920 in the first application and 0.943 in the second, the intraclass correlation scores ranged between good and excellent (0.6 - >0.80). The results show that the adaptation of the CCMQ is valid and ready to be used.
文摘At the invitation of the Chinese Associa-tion for Intermational Understanding,a may-ors'delegation of the Portuguese Socialists Party,composed of eight members and headed by Mr.Ferraz de Abredu,former President of the Portuguese Socialist Party&.Former Dep-uty-Speaker of the Parliament of the Republic of Portugal,visited China during the 2nd to the l0th June 1996.The delegation was met re-spectively by Mr.Wei Jianxing,Member of the Political Bureau of the CPC Central Commit-tee&.member of the CPC Secretariat,and Mr.Wan Guoquan,Vice-Chairman of the CPPCC National Committee and Vice President of the CAFIU.
文摘This study presents a pictorial analysis of Portuguese advertisements from a visual semiotic perspective,particularly the symbolic attributive and suggestiveprocesses.Aiming toelucidate the relationship between genreand gender,the study explored advertising genre,masculinity in advertisements,and the antithesis of man as primary theoretical concerns.The data consisted of five pictures from Portuguese advertisements.The analysis suggests that advertisements are a textual arena where not only genre but also gender is constructed and modified in collaboration.The image of the antithesis of man coexisting with the one of normative masculinity in the five Portuguese advertisements indicates that genre and gender are mutually and simultaneously fluid,with their boundary often blurred.That advertisements are often prone to changes in their function to attract customers implies new and evolving presentation forms of genre and gender.The combination of new and conventional images of masculinity,as shown in the analysis,impacts social and linguistic practices,particularly the fact that traditional norms of defining genre and gender,despite their resemblant quality,might be occasionally challenged or reconstructed inlate-modern culture.
文摘Josefa Figueira de Ayala de Cabrera D’Óbidos was a renowned Baroque painter from Portugal who lived between 1630 and 1684.She was an accomplished artist and one of the most notable female artists of her time.Her works included both secular and religious themes,and she used a variety of mediums with great skill.Despite having different surnames,she signed her paintings under Josepha emÓbidos.This article concentrates on the artist’s landscapes(vedute)and integrated still-life paintings(bodegones).It delves into her capacity to depict the changing seasons through these themes.Josefa expertly combined Baroque tenebrism and illusionism with her love of Nature,highlighting both the physical and spiritual aspects of the natural world.Her paintings are visually captivating,with beautiful colors and intricate details.She incorporated emblematic and mystical symbolism,which added to their spiritual significance in portraying the flora and fauna of her homeland.
文摘Necropsies and extensive histological evaluation for clinical and sub-clinical disease of approximately three hundred Portuguese Water dogs are available as part of an ongoing study to assess their state of health at the end of life. Throughout life these dogs enjoyed a variety of lifestyles and environments. Here we carry out retrospective quantitative assessments of life-time dietary input and physical activity for each dog. To do this, collagens from skull vault bone and from dentine have been analyzed for ratios of stable isotopes to determine differences in diet that individual dogs experienced during late or early life respectively. Robustness of skull bone (weight/unit of skull size) was used as a relative indicator of the amount of physical activity experienced during a dog’s lifetime. These environmental parameters were correlated with the frequency and severity of specific disease processes determined at necropsy. Both measures were shown to exert significant low-level
文摘The aim of this work was to evaluate the effect of different olive leaf extracts (OLE) from different leaf growing stages on human carcinoma cell lines. OLE were tested in human carcinoma cell lines in vitro and cells were plated in 96-microtiter culture plates for each OLE concentration. Fresh (F) and freeze-dried (FD) leaves exhibited phenolic compounds in the range of 2.09 ± 0.10 to 8.44 ± 0.64 and 7.72 ± 0.56 to 24.65 ± 1.9 mg gallic acid equivalents/g leaves, respectively. OLE from several Portuguese olive tree cultivars were found to inhibit the growth of human carcinoma cell lines in a range of 2.09 - 8.44 μg phenolic compound/well (209 - 844 μg/ml) and 0.07 - 2.40 μg phenolic compounds/well (7 - 240 μg/ml) for fresh and freeze-dried leaves, respectively. Young (Y) leaves have revealed the highest cell growth inhibition ranging from about 95% for Cobran?osa, followed by 90% for Cobran?osa, 90% for Arbequina and 75% for Arbequina for cell lines A549, HeLa, A431 and OE21, respectively. The lowest cell growth inhibition (35%) was observed for Galega (Y) leaf extract on cell line A549. However, FD samples exhibited a distinctive pattern since cell growth inhibition was highest at highest extract dilution tested, for A431 (Galega Y) followed by A549 (Cobran?osa Y) with cell inhibition of 75% and 70%, respectively. The data presented in this work strongly suggest that OLEs inhibit the growth of human carcinoma cell lines.
基金CENTRO 2020,PROVERE-Operational Program CENTRO-04-3928-FEDER-000009,Strawberry TreeInnovation Platform Action,Portugal 2020 and European Union by FEDER and by COOP4PAM-Cooperar para crescer no setor das plantas aromáticas e medicinais-Projeto INTERREG/Programa Espanha-Portugal(POCTEP),0665_COOP4PAM_4_P.
文摘L.stoechas subsp.luisieri is one of the five spontaneous species of the genus Lavandula that occurs spontaneously in Portugal.The chemical profile and antifungal activity of L.stoechas subsp.luisieri essential oils were investigated.The essential oil of two phenological stages was isolated by hydrodistillation and their chemical components analyzed by GC-FID/GC-MS.The minimum inhibitory concentration(MIC)and the minimum fungicidal concentration(MFC)of both essential oils were determinate to verify antifungal activity against different strains of fungi isolated from strawberry tree.The fungi tested were Aspergillus carbonarius,Rhizopus stolonifer,Penicillium brevicompactum,Aureobasidium pullulans and Saccothecium rubi.Essential oils were characterized by a high percentage of oxygenated monoterpenes(46-64%)such as trans-α-necrodyl acetate(12.58%),fenchone(5.97%),1,8-cineole(4.84%)and 5-methylene-2,3,4,4-tetramethylcyclopenten-2-enone(10.97%)were the major compounds in essential oil from dormancy stage,while the main compounds in flowering stage were trans-α-necrodyl acetate(26.90%),trans-α-necrodol(13.02%),lavandulyl acetate(6.53%)and linalool(5.82%).A strong antifungal activity of the essential oils was found against all strains,with MIC and MFC values ranged from 0.07-0.29μL/mL and 0.58-9.33μL/mL,respectively.
文摘Continuous changes in vehicle technology,road condition,traffic compositions initiate the change or updating of road users’cost models.So that it needs to practice a continuous revision or update periodically for realistic estimation of costs and benefits.This paper presented the relationship and comparison between road users’cost along Addis Ababa-Adama newly constructed expressway using the Highway Development and Management(HDM-4)Software and manually using formulations developed in the Portuguese model.The method started with data collection.All input data were collected from primary and secondary sources.The primary data utilized an interview,and secondary data were sourced out from pertinent documents,both published and unpublished.More data were gathered that related to vehicles.The vehicles using the road are classified based on the manual from the Ethiopian Road Authority as cars,utilities,small bus,large bus,small truck,medium truck,heavy truck,and truck trailer.The collected data have been input into the HDM-4 interface;the output of the analysis was vehicle operating costs,travel time,and road users’cost as a summation.Using manual technique and HDM-4 Software,Birr 128.62/km/vehicle and Birr 139.23/km/vehicle,respectively,were found from road users’costs analysis.The result shows the difference of Birr 10.61.Also,the correlation coefficient of 0.75 is determined,which shows that the two results of road users’costs are highly related.As a result,the study reveals that the application of HDM-4 Software and the manual technique formulations from the Portuguese model can be adopted interchangeably to calculate Road Users’Cost of road sections in Ethiopia.Hence,the study results are expected to be an eye-opener for a future similar project by the concerned agencies.
