Objective:To analyze domestic and international studies on the effects of positive thought intervention therapy on negative emotions and the quality of life of stroke patients to provide a reference for future related...Objective:To analyze domestic and international studies on the effects of positive thought intervention therapy on negative emotions and the quality of life of stroke patients to provide a reference for future related studies.Methods:Using the scoping review method as a guide,computer searches of PubMed,Web of Science,Embase,Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,China Vipers Full Text Database and China Biomedical Literature Database were conducted to collect relevant studies on the application of positive thinking interventions in stroke patients from the establishment to January 2023,and the literature was screened according to the inclusion and exclusion criteria,and the data were extracted and analyzed by two investigators independently.Results:The search yielded 964 publications,and a total of 19 were included.The time of publication,study site,study population,study design,study length,and type of results of the included studies was summarized and analyzed.Conclusions:Positive thinking-based interventions have shown significant changes in negative emotions such as anxiety and depression in stroke patients and can reduce somatic pain,enhance their social integration,and improve their quality of life.However,interventions in the areas of self-compassion,artificial intelligence and the adoption of tailoring need to be further explored.展开更多
BACKGROUND Lower body positive pressure(LBPP)treadmill has potential applications for improving the gait of patients after stroke,but the related mechanism remains unclear.CASE SUMMARY A 62-year-old male patient suffe...BACKGROUND Lower body positive pressure(LBPP)treadmill has potential applications for improving the gait of patients after stroke,but the related mechanism remains unclear.CASE SUMMARY A 62-year-old male patient suffered from ischemic stroke with hemiplegic gait.He was referred to our hospital because of a complaint of left limb weakness for 2 years.The LBPP training was performed one session per day and six times per week for 2 wk.The dynamic plantar pressure analysis was taken every 2 d.Meanwhile,three-digital gait analysis and synchronous electromyography as well as clinical assessments were taken before and after LBPP intervention and at the 4-wk follow-up.During LBPP training,our patient not only improved his lower limb muscle strength and walking speed,but more importantly,the symmetry index of various biomechanical indicators improved.Moreover,the patient’s planter pressure transferring from the heel area to toe area among the LBPP training process and the symmetry of lower body biomechanical parameters improved.CONCLUSION In this study,we documented a dynamic improvement of gait performance in a stroke patient under LBPP training,which included lower limb muscle strength,walking speed,and symmetry of lower limb biomechanics.Our study provides some crucial clues about the potential dynamic mechanism for LBPP training on gait and balance improvement,which is related to rebuilding foot pressure distribution and remodeling symmetry of biomechanics of the lower limb.展开更多
Introduction: Herpes simplex virus is the most common etiology for life-threatening sporadic encephalitis worldwide. Antiviral therapy with acyclovir has been shown to reduce mortality and should be started promptly i...Introduction: Herpes simplex virus is the most common etiology for life-threatening sporadic encephalitis worldwide. Antiviral therapy with acyclovir has been shown to reduce mortality and should be started promptly in patients with clinically suspected viral encephalitis before serological confirmation of the diagnosis. Despite antiviral treatment, it is associated with significant mortality and a wide range of neurologic sequelae or neuropsychiatric disorders. Clinical presentation includes fever, headache, altered mental status, and focal or generalized seizures. In some cases, it can present with focal neurological deficits, such as an acute stroke. The aim of this study is to identify rare complications of HSVE. Presentation: We present a case of a 71-year-old female patient with herpes virus encephalitis and an ischemic cerebral accident. The findings of CT scan of the brain revealed an extensive right temporal hypodensity. CSF findings include an elevated protein level, normal glucose level and pleocytosis with lymphocyte predominance. The lumbar tap confirmed the presence of herpes simplex virus type 1 with polymerase chain reaction (PCR) in the CSF. Neurological manifestations include focal neurological deficit with left-sided hemiparesis and coma. After 40 days of complex therapy, an improvement in the mental state was observed. Conclusion: There are varying degrees of neurologic sequelae among survivors in children and adults despite the antiviral treatment. Herpes simplex encephalitis has significant morbidity and high mortality due to the lack of prophylactic treatment and preventable strategies.展开更多
Objective:To explore the influencing factors and logistic regression characteristics of cryptogenic stroke in patients with positive transcranial doppler bubble test(c-TCD).Methods:A total of 134 cases of cryptogenic ...Objective:To explore the influencing factors and logistic regression characteristics of cryptogenic stroke in patients with positive transcranial doppler bubble test(c-TCD).Methods:A total of 134 cases of cryptogenic stroke that were diagnosed by Tianshui First People's Hospital from November 2018 to April 2020 were selected according to the TOAST(Trial of ORG 10172 in Acute Stroke Treatment)classification criteria.According to c-TCD results,there were 70 cases of right to left shunt that were included in the positive group and 64 cases without right to left shunt in the negative group.Gender,age,smoking,diabetes,hypertension,and factors affecting the positive rate of foam were analyzed.According to the abnormal embolism scale scores,logistic regression equation was used to analyze the independent influencing factors.Results:The influencing factors of cryptogenic stroke in patients with positive c-TCD were correlated with age,gender,and abnormal embolism scale scores(p<0.05).For each grade increase in age,the proportion of positive foam test was calculated to be 3.21 times,and the proportion of female to male was calculated to be 2.25 times.For each grade increase in the scores,the proportion of positive foam test was calculated to be 2.55 times.Conclusion:Female,older age,and higher scores in the abnormal embolism scale are the influencing factors for cryptogenic stroke in patients with positive c-TCD.展开更多
文摘Objective:To analyze domestic and international studies on the effects of positive thought intervention therapy on negative emotions and the quality of life of stroke patients to provide a reference for future related studies.Methods:Using the scoping review method as a guide,computer searches of PubMed,Web of Science,Embase,Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,China Vipers Full Text Database and China Biomedical Literature Database were conducted to collect relevant studies on the application of positive thinking interventions in stroke patients from the establishment to January 2023,and the literature was screened according to the inclusion and exclusion criteria,and the data were extracted and analyzed by two investigators independently.Results:The search yielded 964 publications,and a total of 19 were included.The time of publication,study site,study population,study design,study length,and type of results of the included studies was summarized and analyzed.Conclusions:Positive thinking-based interventions have shown significant changes in negative emotions such as anxiety and depression in stroke patients and can reduce somatic pain,enhance their social integration,and improve their quality of life.However,interventions in the areas of self-compassion,artificial intelligence and the adoption of tailoring need to be further explored.
基金National Natural Science Foundation for Young Scientists of China,No.81902281Guangdong Medical Science and Technology Research Foundation of China,No.A2019120 and No.A2020362and Special Project of Chinese Government for Science and Technology of Guangdong Province,No.2019SKJ003.
文摘BACKGROUND Lower body positive pressure(LBPP)treadmill has potential applications for improving the gait of patients after stroke,but the related mechanism remains unclear.CASE SUMMARY A 62-year-old male patient suffered from ischemic stroke with hemiplegic gait.He was referred to our hospital because of a complaint of left limb weakness for 2 years.The LBPP training was performed one session per day and six times per week for 2 wk.The dynamic plantar pressure analysis was taken every 2 d.Meanwhile,three-digital gait analysis and synchronous electromyography as well as clinical assessments were taken before and after LBPP intervention and at the 4-wk follow-up.During LBPP training,our patient not only improved his lower limb muscle strength and walking speed,but more importantly,the symmetry index of various biomechanical indicators improved.Moreover,the patient’s planter pressure transferring from the heel area to toe area among the LBPP training process and the symmetry of lower body biomechanical parameters improved.CONCLUSION In this study,we documented a dynamic improvement of gait performance in a stroke patient under LBPP training,which included lower limb muscle strength,walking speed,and symmetry of lower limb biomechanics.Our study provides some crucial clues about the potential dynamic mechanism for LBPP training on gait and balance improvement,which is related to rebuilding foot pressure distribution and remodeling symmetry of biomechanics of the lower limb.
文摘Introduction: Herpes simplex virus is the most common etiology for life-threatening sporadic encephalitis worldwide. Antiviral therapy with acyclovir has been shown to reduce mortality and should be started promptly in patients with clinically suspected viral encephalitis before serological confirmation of the diagnosis. Despite antiviral treatment, it is associated with significant mortality and a wide range of neurologic sequelae or neuropsychiatric disorders. Clinical presentation includes fever, headache, altered mental status, and focal or generalized seizures. In some cases, it can present with focal neurological deficits, such as an acute stroke. The aim of this study is to identify rare complications of HSVE. Presentation: We present a case of a 71-year-old female patient with herpes virus encephalitis and an ischemic cerebral accident. The findings of CT scan of the brain revealed an extensive right temporal hypodensity. CSF findings include an elevated protein level, normal glucose level and pleocytosis with lymphocyte predominance. The lumbar tap confirmed the presence of herpes simplex virus type 1 with polymerase chain reaction (PCR) in the CSF. Neurological manifestations include focal neurological deficit with left-sided hemiparesis and coma. After 40 days of complex therapy, an improvement in the mental state was observed. Conclusion: There are varying degrees of neurologic sequelae among survivors in children and adults despite the antiviral treatment. Herpes simplex encephalitis has significant morbidity and high mortality due to the lack of prophylactic treatment and preventable strategies.
基金The research belongs to the stage result of a project(Project plan number:2021-SHFZKJK-5207).
文摘Objective:To explore the influencing factors and logistic regression characteristics of cryptogenic stroke in patients with positive transcranial doppler bubble test(c-TCD).Methods:A total of 134 cases of cryptogenic stroke that were diagnosed by Tianshui First People's Hospital from November 2018 to April 2020 were selected according to the TOAST(Trial of ORG 10172 in Acute Stroke Treatment)classification criteria.According to c-TCD results,there were 70 cases of right to left shunt that were included in the positive group and 64 cases without right to left shunt in the negative group.Gender,age,smoking,diabetes,hypertension,and factors affecting the positive rate of foam were analyzed.According to the abnormal embolism scale scores,logistic regression equation was used to analyze the independent influencing factors.Results:The influencing factors of cryptogenic stroke in patients with positive c-TCD were correlated with age,gender,and abnormal embolism scale scores(p<0.05).For each grade increase in age,the proportion of positive foam test was calculated to be 3.21 times,and the proportion of female to male was calculated to be 2.25 times.For each grade increase in the scores,the proportion of positive foam test was calculated to be 2.55 times.Conclusion:Female,older age,and higher scores in the abnormal embolism scale are the influencing factors for cryptogenic stroke in patients with positive c-TCD.
