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Analysis of Ornidazole Injection in Clinical Use at Post-marketing Stage by Centralized Hospital Monitoring System 被引量:4
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作者 Ying ZHAO Zhe CHEN +3 位作者 Pu HUANG Si-wei ZHENG Qi-ling XU Chen SHI 《Current Medical Science》 SCIE CAS 2019年第5期836-842,共7页
This study aims to analyze the clinical use of ornidazole injection at the post-marketing stage by centralized hospital monitoring system method,and investigate its widespread use in patients,in order to regulate and ... This study aims to analyze the clinical use of ornidazole injection at the post-marketing stage by centralized hospital monitoring system method,and investigate its widespread use in patients,in order to regulate and guide the rational drug use,improve the drug specificity and provide a basis for drug therapy.The study adopts a prospective,multi-center,large sample size,centralized hospital monitoring system.We selected five leading hospitals in Hubei province,and observed the inpatients who received the ornidazole injection from July 1,2015 to October 31,2015.The basic information of patients was recorded,as well as the drug use and adverse events.The statistical analysis was performed based on these data.A total of 4396 individuals were enrolled in this study,most of them were middle-aged female patients and the ornidazole injection was mainly used as prophylactic prior to surgery to prevent the infections,and surgical treatment of anaerobic infections,abdominal infections and pelvic infections.The irrational drug use existed mainly in the prescribing and administration process,including unreasonable dosing frequency,rapid intravenous drip speed and extended duration of drug use.Eleven cases of adverse reactions were collected during the monitoring,incidence rate of adverse reactions was 2.5‰;adverse drug reactions occurred within 30 min.The study results fully reflected the usage of ornidazole injection in the real world.Based on the study,we calculated the adverse reaction incidence of ornidazole and identified the risk factors which may affect the safety of ornidazole injection.Study results strongly recommend that the manufacturers should publish standards for inpatient use and doctors should prescribe with caution accordingly. 展开更多
关键词 ORNIDAZOLE injection CENTRALIZED HOSPITAL monitoring system post-marketing reassessment clinical use ADVERSE reaction
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Reassessment of the Resources of a Deep Aquifer System under Physical and Chemical Constraints:The Maastrichtian Aquifer
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作者 Cheikh Hamidou Kane Moustapha Diene +2 位作者 Meissa Fall Baba Sarr Alassane Thiam 《Journal of Water Resource and Protection》 2012年第4期217-223,共7页
The deep and confined Maastrichtian aquifer contains considerable groundwater resources. It stretches over nearly 200,000 km2, from the northern part of Mauritania to the South of Guinea Bissau where it becomes shallo... The deep and confined Maastrichtian aquifer contains considerable groundwater resources. It stretches over nearly 200,000 km2, from the northern part of Mauritania to the South of Guinea Bissau where it becomes shallow. The reservoir is composed mainly of coarse sands and sandstone interbedded with some clay units. The aquifer provides 40% of the total drinking water extracted from the different aquifers and nearly 800 wells equally distributed operate only in the top 50 m of the aquifer. Despite the importance of these resources for providing water in the rural and urban areas, the aquifer characteristics are not well defined. The present paper aims to define first the physical and chemical characteristics of the Maastrichtian aquifer. The reserve of the aquifer initially estimated at 350 billion m3, is reassessed using new data providing from cross sections realized as part of our research, through the Water Sectorial Project of the Ministry of Hydraulics. Data from oil wells and geophysical logging are used to investigate the geometry of the aquifer and the position of the fresh/salty water interface. The highest thickness of the aquifer is between 200 to 400 m and salty water is present below the fresh groundwater in the west side of the aquifer. In the Eastern side, potable water lies directly above the basement. The thickness of the aquifer increases from the west to the center, and then decreases towards the shallow basement rock in the South East. The average thickness is 250 m. Chemical data coming from pumping wells indicate high chloride (250 - 1600 mg/l) and fluoride content (1 - 5.5 mg/l). Therefore, the reassessment has to take into account the chemical aspect of the water. 展开更多
关键词 MAASTRICHTIAN GROUNDWATER DEEP AQUIFER Senegalese-Mauritanian SEDIMENTARY Basin Characteristic Pollution reassessment
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How to establish precise proprietary Chinese medicine in post-marketing reappraisal?
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作者 Ran Tian Liang Dai +2 位作者 Hong-Cai Shang You-Ping Li Zhao-Xiang Bian 《Traditional Medicine Research》 2017年第4期155-160,共6页
The clinical efficacy and safety of proprietary Chinese medicine has become a more prevailing public health concern.The China Food and Drug Administration has pushed drug companies to conduct post-marketing reappraisa... The clinical efficacy and safety of proprietary Chinese medicine has become a more prevailing public health concern.The China Food and Drug Administration has pushed drug companies to conduct post-marketing reappraisal for proprietary Chinese medicine to provide additional evidence supporting the efficacy and safety of these medicine.In this paper,we propose a reappraisal protocol called“precise proprietary Chinese medicine”to precisely i)define the therapeutic aim;ii)design the protocol;iii)control the quality of proprietary Chinese medicine;iv)implement the protocol in the trial;v)study the mechanism-of-action of the proprietary Chinese medicine and vi)describe the indications of the proprietary Chinese medicine.We hope that these steps facilitate the post-marketing reappraisal of proprietary Chinese medicine. 展开更多
关键词 Traditional Chinese medicine post-marketing reappraisal Precise Chinese medicine
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Safety and Efficacy of Combination Therapy with Insulin Glargine and Oral Hypoglycaemic Agents Including DPP-4 Inhibitors in Japanese T2DM Patients: ALOHA 2 Study, a Post-Marketing Surveillance for Lantus<sup>&reg;</sup>
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作者 Masayuki Kobayashi Shoko Tsukube +1 位作者 Yukio Ikeda Yujin Shuto 《Journal of Diabetes Mellitus》 2014年第4期273-289,共17页
Aims: In the Add-on Lantus&reg;?to Oral Hypoglycaemic Agents 2 (ALOHA 2) Study in Japanese adults with type 2 diabetes mellitus (T2DM), data on the safety and efficacy of combination therapy with insulin glargine ... Aims: In the Add-on Lantus&reg;?to Oral Hypoglycaemic Agents 2 (ALOHA 2) Study in Japanese adults with type 2 diabetes mellitus (T2DM), data on the safety and efficacy of combination therapy with insulin glargine (Lantus&reg;) and oral anti-hyperglycaemic drugs (OADs) including dipeptidyl peptidase-4 (DPP-4) inhibitors in a real-life setting were collected and analyzed. Methods: This postmarketing surveillance was a prospective, observational, 24-week study that complied with the pharmaceutical affairs law and the ministerial ordinance of “Good Post-Marketing Study Practice (GPSP)” in Japan. Safety, efficacy and patient-reported outcomes (PROs);patients’ satisfaction with treatment (DTSQs and DTSQc) and patients’ self-reported health (EQ-5D and EQ-VAS) of combination therapy of insulin glargine and OADs were evaluated. Results: A total of 2,630 patients were enrolled. Of the 2,602 patients in the safety analysis population, 161 patients experienced 175 cases of adverse drug reactions, and the major adverse drug reaction was hypoglycaemia (140 patients, 5.38%). Out of those with hypoglycaemia, 11 patients (0.42%) had severe hypoglycaemia and the incidence rate (episodes per patient-year) was 0.019. Basal supported oral therapy (BOT) with insulin glargine substantially reduced the HbA1c, FPG and 2 hour-PPG levels for 24 weeks by -1.61%, -54.4 mg/dL and -74.5 mg/dL respectively. The mean weight was increased, however the change was +0.50 kg. In addition, the treatment satisfaction scores of DTSQs (mean treatment satisfaction score increased 3.6 from baseline to last observation) and DTSQc, EQ-5D index scores and EQ-VAS scores were significantly improved. Conclusion: Insulin glargine and OADs combination therapy was suggested to be effective and well tolerated. Patients’ satisfaction with treatment and their self-reported health improved in spite of the addition of injections to oral agents. The combination therapy of insulin glargine and OADs including DPP-4 inhibitors is likely to be considered an important therapeutic option in the diabetic patients. 展开更多
关键词 ALOHA 2 Insulin GLARGINE Patient-Reported Outcomes post-marketing Surveillance STUDY Type 2 Diabetes
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文学评价体系的确立与经典作家作品的价值重估
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作者 王卫平 曹庆慧 《河北学刊》 北大核心 2024年第1期37-44,共8页
回顾文学批评和文学研究,从新时期、新世纪到新时代已取得了公认的成就,但也存在若干问题和不足。如何提升文学批评和文学研究的影响力、公信力?如何增强文学研究的体系性和原创力?如何更大地发挥文学批评的作用?这是摆在我们面前的严... 回顾文学批评和文学研究,从新时期、新世纪到新时代已取得了公认的成就,但也存在若干问题和不足。如何提升文学批评和文学研究的影响力、公信力?如何增强文学研究的体系性和原创力?如何更大地发挥文学批评的作用?这是摆在我们面前的严峻课题。我们首先要建构起科学的、完整的文学评价体系和正确的价值取向。然后,以此重估经典作家作品的价值,完成再解读、再阐释和价值重估的重任,这是今后文学研究的主要任务之一,也是延续经典作家作品生命力的主要途径,更是加快构建中国特色文学“三大体系”的重要举措。而文本发现、理论激发、现实激活是经典作家作品再阐释和价值重估的三条路径。 展开更多
关键词 评价体系 价值取向 经典作家作品 重估 基本路径
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基于文献分析的疏血通注射液上市后临床安全性再评价
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作者 杨玉晴 江程 +5 位作者 李春晓 李学林 陈玉欢 王士挺 凌霄 赵娅 《中国医院用药评价与分析》 2024年第2期237-241,共5页
目的:对疏血通注射液上市后临床安全性的文献进行再评价研究,获取药品临床安全性信息,为临床安全用药提供参考。方法:检索截至2023年5月中国知网、万方数据库、维普数据库、中国生物医学文献数据库、PubMed中收载的疏血通注射液的药品... 目的:对疏血通注射液上市后临床安全性的文献进行再评价研究,获取药品临床安全性信息,为临床安全用药提供参考。方法:检索截至2023年5月中国知网、万方数据库、维普数据库、中国生物医学文献数据库、PubMed中收载的疏血通注射液的药品不良反应(ADR)/药品不良事件(ADE)文献,采用描述性分析方法,对ADR/ADE发生特点进行总结分析。结果:纳入212篇符合标准的文献,其中临床研究151篇,个案报告41篇,安全性监测20篇,共报告ADR/ADE 1361例。疏血通注射液的不良反应累及16个器官和或(系统),90种临床表现,合计2109例次,主要集中在皮肤及其附件损害(637例次,占30.20%),表现为皮疹、瘙痒、皮肤红肿等;其次是胃肠系统损害(447例次,占21.19%),表现为恶心、呕吐、腹泻等。802例给出了具体用药剂量,其中发生ADR/ADE的单次超剂量(>6 mL)使用情况占11.10%(89例)。314例有ADR/ADE发生时间的具体描述,其中给药后0~30 min发生的占36.94%(116例),>7 d发生的占11.78%(37例)。319例记录了ADR/ADE处理转归情况,其中317例好转或痊愈。严重的ADR/ADE共发现9例,表现为上消化道出血、严重皮疹、过敏性休克等。结论:通过描述性文献研究可以系统梳理疏血通注射液相关ADR/ADE的发生时间、临床表现、累及器官和(或)系统、ADR转归及预后情况,为其临床合理应用和安全监管提供参考。 展开更多
关键词 疏血通注射液 药品不良反应 药品不良事件 安全性 再评价 文献分析
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基于认知重评的心理干预对急诊科护士专业生活品质及自我调节疲乏水平的影响
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作者 许雪峰 王俊锋 《河南医学研究》 CAS 2024年第14期2596-2599,共4页
目的探索基于认知重评的心理干预对急诊科护士专业生活品质及自我调节疲乏水平的影响。方法选取2022年1—12月郑州市某三级甲等综合医院63名急诊科护士为研究对象。对照组接受常规业务学习和心理辅导、教育;观察组在对照组的基础上接受... 目的探索基于认知重评的心理干预对急诊科护士专业生活品质及自我调节疲乏水平的影响。方法选取2022年1—12月郑州市某三级甲等综合医院63名急诊科护士为研究对象。对照组接受常规业务学习和心理辅导、教育;观察组在对照组的基础上接受认知重评的心理干预措施。干预后调查两组护士专业生活品质、自我调节疲劳程度。结果两组干预后慈心满意、工作倦怠、二次创伤得分差异有统计学意义(P<0.05);两组干预后认知控制、情绪控制、行为控制得分差异有统计学意义(P<0.05)。结论基于认知重评的心理干预有助于提高急诊科护士的专业生活品质,降低护士的自我调节疲劳水平。 展开更多
关键词 认知重评 急诊科护士 专业生活品质 自我调节疲劳
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高州市泗水镇龙胆塘水库防洪能力复核分析
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作者 周子宜 《陕西水利》 2024年第1期50-53,共4页
水库防洪能力复核是水库安全评价工作中的一项重要内容。选取高州市泗水镇龙胆塘水库为分析对象,对其防洪能力进行复核分析。首先,利用综合单位线法与推理公式法对设计洪水进行复核计算;其次,根据水量平衡原理进行水库调洪计算;然后,在... 水库防洪能力复核是水库安全评价工作中的一项重要内容。选取高州市泗水镇龙胆塘水库为分析对象,对其防洪能力进行复核分析。首先,利用综合单位线法与推理公式法对设计洪水进行复核计算;其次,根据水量平衡原理进行水库调洪计算;然后,在此基础上进行大坝坝顶高程和泄洪能力复核;最后,对该水库防洪能力进行综合评价。结果表明:高州市泗水镇龙胆塘水库的防洪能力满足各项要求,大坝防洪安全性为B级。研究成果可为其他水库的防洪能力复核工作提供参考。 展开更多
关键词 水库 防洪能力复核 水量平衡原理 调洪演算
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Reassessing Growth
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作者 Zhou Xiaoyan 《ChinAfrica》 2014年第5期40-41,共2页
CHINA'S economic growth slipped to 7.4 percent in the first quarter, signaling more downward pres-sure for the world's second largest economy, However. authorities have ruled out the possibility of major stimulus to... CHINA'S economic growth slipped to 7.4 percent in the first quarter, signaling more downward pres-sure for the world's second largest economy, However. authorities have ruled out the possibility of major stimulus to fight short-term dips in growth and plan to seek growth momentum through deep-seated reforms and reinvigorated domestic consumption. 展开更多
关键词 reassessing Growth NBS JUN GDP
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基于幸福素养理论的军校学员团体心理训练的干预研究
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作者 贾臻 吕恬歌 +5 位作者 杜军 罗青青 阳逸 杨婉君 谭鑫杰 杨国愉 《陆军军医大学学报》 CAS CSCD 北大核心 2023年第22期2370-2379,共10页
目的探索基于幸福素养理论的军校学员团体心理训练对个体幸福素养、认知重评、心理韧性和主观幸福感的干预效果。方法采用整群抽样法,抽取某军校本科学员116人,按所在学员队模拟排分为两组,实验组58人,对照组58人。实验组共参加7次团体... 目的探索基于幸福素养理论的军校学员团体心理训练对个体幸福素养、认知重评、心理韧性和主观幸福感的干预效果。方法采用整群抽样法,抽取某军校本科学员116人,按所在学员队模拟排分为两组,实验组58人,对照组58人。实验组共参加7次团体心理训练,每周参加2次,每次训练时间为90~100 min,对照组不参加训练。分别在训练前(T1)、训练结束即刻(T2)、训练结束后1个月(T3)使用中文版幸福素养6项量表(Wellbeing Literacy 6 item scale,Well-Lit 6)、主观幸福感量表(General Well-being Schedule,GWBS)、中文版情绪调节问卷(Emotion Regulation Questionnaire,ERQ)的认知重评分量表、简版心理弹性量表(Connor-Davidson resilience scale,CD-RISC-10)对两组学员进行评估。结果训练前两组学员人口统计学信息及各心理学指标差异均无统计学意义(P>0.05)。①幸福素养总分的分组×时间交互效应显著(P<0.05);②认知重评得分的分组×时间交互效应显著(P<0.001);③心理韧性得分的分组×时间交互效应显著(P<0.001);④主观幸福感总分的分组×时间交互效应显著(P<0.001)。结论基于幸福素养理论的军校学员团体心理训练能够提升军校学员的幸福素养,改善其认知重评策略,提高其心理韧性,增强其主观幸福感。 展开更多
关键词 幸福素养 团体心理训练 军校学员 认知重评 心理韧性 主观幸福感
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Outcome of Patients with Lower Limbs Deep Vein Thrombosis at the University Hospital of Brazzaville (The Republic of the Congo)
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作者 Stéphane Méo Ikama Eric Gibrel Kimbally Kaky +4 位作者 Jospin Makani Fresnel Ngoma Mabondzo Thibaut Naïbe Gankama Bijou Moualengue Suzy Gisèle Kimbally Kaky 《World Journal of Cardiovascular Diseases》 2023年第12期845-853,共9页
The aim of this study was to describe the characteristics of patients with deep vein thrombosis (DVT) of the pelvic limbs at the time of diagnosis, and their course after hospitalization, in order to improve the manag... The aim of this study was to describe the characteristics of patients with deep vein thrombosis (DVT) of the pelvic limbs at the time of diagnosis, and their course after hospitalization, in order to improve the management of DVT in our context. This was a descriptive longitudinal study, based on cases of deep vein thrombosis recorded between 1 January 2015 and 30 September 2018, in the cardiology and internal medicine department of the Brazzaville University Hospital Centre. During the study period, 4678 patients were hospitalized, including 52 with DVT. Thirty-three were reassessed. The frequency of DVT was 1.1% and the average hospitalization rate was 13.9 cases/year. The 33 patients were divided into 20 women and 13 men (sex ratio: 0.65). The mean age of the patients was 51.4 ± 17.8 years (extremes: 16 and 85 years). The main aetiological factors were cancer (19.1%), sickle cell disease (3%) and HIV immunosuppression (3%). The predominant risk factors were: prolonged immobilization (42.9%), pregnancy, long travel and obesity in the same number of cases (n = 3, i.e. 14.2%). The DVT involved the left pelvic limb in 75.8% of cases. Anticoagulants were administered in all patients, and compression stockings were worn in 97% of cases. The mean time to re-evaluation was 10.9 ± 9.4 months (extremes: three and 35 months). The mean measurements of the limb where the thrombosis had occurred at diagnosis and reassessment showed a significant difference. Venous Doppler showed compressible veins (60.6%), varicosities (36.3%), incompressible veins (30.3%) and thrombus (21.2%). Complications were: post-phlebitic disease (42.4%), death (21.2%), pulmonary embolism (18.2%), recurrence (18.2%). The DVT remains relatively rare, and its conventional therapeutic management is satisfactory. Systematic venous Doppler ultrasound reassessment should enable patients at risk of recurrence to be identified. 展开更多
关键词 Deep Vein Thrombosis reassessment COMPLICATIONS CONGO
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燃气SCADA报警设置点再评估研究
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作者 彭超龙 陈媛秀 杨秀平 《石油化工自动化》 CAS 2023年第4期27-32,共6页
以某天然气门站为例,介绍了报警点设置的目的,建立了报警设置点再评估工作流程。采用头脑风暴与专家评审相结合的方法,梳理了每一个报警设置点产生的原因、可能造成的后果以及报警响应动作与时间,并对因果联锁报警和重复设置报警点进行... 以某天然气门站为例,介绍了报警点设置的目的,建立了报警设置点再评估工作流程。采用头脑风暴与专家评审相结合的方法,梳理了每一个报警设置点产生的原因、可能造成的后果以及报警响应动作与时间,并对因果联锁报警和重复设置报警点进行了识别,经评审后报警设置点总量减少了23。17%,为改善燃气数据采集与监控系统(SCADA)报警泛滥提供了目标报警点。 展开更多
关键词 天燃气 数据采集与监控系统 报警设置点 再评估 报警泛滥
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从“大同小异”看中国戏曲的传承和创新——以徐勤纳戏曲导演艺术为例
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作者 刘晓丽 《黑河学院学报》 2023年第4期164-168,共5页
当前,面对技术、信息、资本以及权力融合叠加的社会,传统戏曲艺术作为中华优秀传统文化的时代价值不断受到挑战,重估戏曲艺术的价值成为一项重要工作,同时,推动戏曲艺术的传承和创新也成为一项长期事业。戏曲艺术要焕发生机和活力,要求... 当前,面对技术、信息、资本以及权力融合叠加的社会,传统戏曲艺术作为中华优秀传统文化的时代价值不断受到挑战,重估戏曲艺术的价值成为一项重要工作,同时,推动戏曲艺术的传承和创新也成为一项长期事业。戏曲艺术要焕发生机和活力,要求从本体论的层面创建戏曲作为一种“人学”舞台艺术的展开方式,从认识论的层面理清戏曲和观众、戏曲创作与传播、社会与自我之间的多重复杂关系。戏曲导演徐勤纳以自己对戏曲的深度理解和敢于创新的实践灵活运用相应的戏曲形式,建立传统与现实相互关照的语义场,打通戏曲艺术时代创新的元认知。 展开更多
关键词 戏曲艺术 徐勤纳 价值重估 传承与创新
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循证医学与中药上市后的再评价 被引量:24
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作者 李廷谦 王刚 王蕾 《中国循证医学杂志》 CSCD 2004年第4期217-221,共5页
目前 ,我国已逐渐开展对上市后药物的不良反应监测 ,并开始重视其对患者生存质量、患者死亡率等指标的影响。已获上市批准的中药中 ,有很多在不良反应的发现和管理上存在时滞现象 ,且在临床有效性和安全性方面存在一定问题。对中药上市... 目前 ,我国已逐渐开展对上市后药物的不良反应监测 ,并开始重视其对患者生存质量、患者死亡率等指标的影响。已获上市批准的中药中 ,有很多在不良反应的发现和管理上存在时滞现象 ,且在临床有效性和安全性方面存在一定问题。对中药上市后的再评价 ,需要有效、规范的评价体系。循证药物评价运用循证医学的理念 ,结合临床流行病学、系统评价、卫生技术评估等手段 ,评价新药和上市后药物的临床有效性、安全性、经济性和适用性 ,对我国中药的现代化与国际化进程具有重要作用。 展开更多
关键词 循证医学 中药 药物不良反应 药品监督 安全性 有效性 药物评价
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Clinical Application Analysis of Andrographolide Total Ester Sulfonate Injection,a Traditional Chinese Medicine Licensed in China 被引量:12
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作者 赵瑛 黄璞 +3 位作者 陈喆 郑思维 喻锦扬 史琛 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2017年第2期293-299,共7页
Andrographolide total ester sulfonate(ATES) injection is one of the products of traditional Chinese medicine(TCM) currently used against viral infection in China.ATES injection was approved for manufacturing and m... Andrographolide total ester sulfonate(ATES) injection is one of the products of traditional Chinese medicine(TCM) currently used against viral infection in China.ATES injection was approved for manufacturing and marketing in January 2002.It is indicated for acute respiratory infections,tonsillitis,chronic obstructive pulmonary disease,influenza,foot and mouth disease,bronchiolitis,herpangina,mumps,infectious mononucleosis and psychosis.However,its usage also carries risk.We investigated the use of ATES at the Wuhan Union Hospital from January 2014 to December 2014 and evaluated its real-world clinical application using the hospital centralized monitoring method.A total of 848 cases were enrolled in this study.In these cases,it was mainly used for postoperative anti-inflammation and treating upper respiratory infection,pneumonia and bronchitis.Among them,39.86% were contraindicated.Irregular medication of adults and children accounted for 1.91% and 23.38%,respectively.Improper choice of solvent accounted for 3.18%.The choice of intravenous drip versus aerosol inhalation was reasonable.A case of adverse events(AEs) was observed in the monitoring period,and the incidence of adverse drug reaction(ADR) of ATES injection was 0.12%.ATES injection in our hospital is relatively safe with a low incidence of adverse reactions.The study assesses the clinical usage and adverse reactions of ATES injection,and provides suggestions for rational use in clinical practice. 展开更多
关键词 andrographolide total ester sulfonate hospital centralized monitoring post-marketing reassessment clinical use adverse reaction
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基于网络的山东地震灾情收集分析处理系统 被引量:21
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作者 董翔 肖兰喜 +2 位作者 杜宪宋 吴晨 刘瑞峰 《华北地震科学》 2007年第3期6-10,33,共6页
本系统借助网络资源,把人们对地震的感觉、看到建筑物震害程度、以及地表破坏和生命线破坏现象迅速地收集、处理和分析,这样可以快速验证和修正地震应急指挥系统基于地震应急数据库给出的地震影响和灾情评估结果,为地震的应急指挥决策... 本系统借助网络资源,把人们对地震的感觉、看到建筑物震害程度、以及地表破坏和生命线破坏现象迅速地收集、处理和分析,这样可以快速验证和修正地震应急指挥系统基于地震应急数据库给出的地震影响和灾情评估结果,为地震的应急指挥决策提供更可靠的基础。并阐述了主要基于J2EE体系结构的灾情收集分析处理系统的基本构架,介绍了适用于该系统的关键技术,同时给出在ORACLE、Weblogic和WebGIS平台上的C/S及B/S实现的解决方案。 展开更多
关键词 网络 地震灾情汇集 评估结果修正 处理系统
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在役导管架平台的评估策略研究现状 被引量:4
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作者 李昕 金峤 周晶 《防灾减灾工程学报》 CSCD 2007年第3期368-376,共9页
海洋平台造价昂贵,所处的海洋环境复杂且恶劣,受到波浪、流、风、冰、地震以及疲劳、腐蚀、冲刷等时变因素的联合作用,检测和维修困难,事故后果严重,所以,为延长在役导管架平台的寿命而进行的评估研究存在许多难题需要解决。针对近海导... 海洋平台造价昂贵,所处的海洋环境复杂且恶劣,受到波浪、流、风、冰、地震以及疲劳、腐蚀、冲刷等时变因素的联合作用,检测和维修困难,事故后果严重,所以,为延长在役导管架平台的寿命而进行的评估研究存在许多难题需要解决。针对近海导管架平台评估标准、检测策略、构件校核、系统分析、维修加固决策和方法等,介绍了国内外的研究现状,并展望了将来需要进一步开展的工作。 展开更多
关键词 近海导管架平台 重评估 研究现状
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从药物经济学看中药注射剂 被引量:27
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作者 张方 周超凡 《中国中药杂志》 CAS CSCD 北大核心 2007年第5期453-456,共4页
从药物经济学的研究视角,对中药注射剂的生产、使用现状进行经济学分析,探讨中药注射剂的资金投入、资源投入情况以及临床健康结果的产出、社会福利的产出情况,明确了中药注射剂占用了大量的医药卫生资源,但产出并不乐观,从而提出上市... 从药物经济学的研究视角,对中药注射剂的生产、使用现状进行经济学分析,探讨中药注射剂的资金投入、资源投入情况以及临床健康结果的产出、社会福利的产出情况,明确了中药注射剂占用了大量的医药卫生资源,但产出并不乐观,从而提出上市后中药注射剂药物经济学评价的重要意义以及进行药物经济学评价的主要内容。 展开更多
关键词 中药注射剂 药物经济学 成本 产出 上市后再评价
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医疗器械供应链中的供需策略研究 被引量:10
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作者 卢光泽 周丹 《中国医院管理》 北大核心 2004年第8期49-51,共3页
供需策略是供应链管理中的重要内容。通过对医疗器械供应链底端的客户价值要素分析,针对供应链上供需的基本模型,提出建立第三方物流、战略联盟或合作伙伴、评测和再评价、规模定制和电子商务等5种策略及其适用范围,并作出评价。
关键词 医疗设备供应链 第三方物流 再评价 规模定制
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胜利电厂一期工程环境影响回顾评价——污染源和污染治理措施回顾评价 被引量:3
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作者 张秀义 周爱国 +2 位作者 闫来洪 赵东风 冯成武 《中国环境监测》 CSSCI CSCD 北大核心 1996年第6期30-34,共5页
本文论述了胜利电厂污染源和污染治理措施回顾评价的方法和内容。回顾评价采用现场调查,与一期环评报告进行对比分析的方法进行,重点放在污染源、污染治理措施的调查分析上。
关键词 电厂 污染源 污染治理 环境影响 回顾 评价
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