Improvement of Atrophic Acne Scar and Skin Complexity by Combination of Aqueous Human Placenta Extract and Mesenchymal Stem Cell Mesotherapy

Atrophic scars, a permanent complication of severe acne, have negative effect on psychology in adolescent. The treatment of atrophic scar is depended on types of scar and it is difficult to improve by a single treatment. Mesenchymal stem cell is a scientific approval for surgery scar treatment and wound healing. We present a case report of female presented with atrophic acne scar distributed on both cheeks. The case aims to prove that the combination of MSCs and aqueous human placenta extract (RGF&#174) contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes. We first found that MSCs-contained human placenta extract solution combination subcision improves the atrophic acne scar and skin complexity by enhancement of skin cell regeneration.

Effective Treatment of Atrophic and Icepick Acne Scars Using Deep Non-Ablative Radiofrequency and Multisource Fractional RF Skin Resurfacing

Background and Objectives: Effective treatment for atrophic (depressed) and icepick acne scars requires treatment of both epidermis—for roughness, texture and hyperpigmentation, and the dermis—for collagen remodeling. All first generation radiofrequency systems allow nonablative RF treatment while a few others allow simple bipolar Fractional RF skin resurfacing. The FDA cleared multisource radiofrequency therapy system (EndyMed PRO, EndyMed Ltd., Cesarea, Israel) allows, for the first time, phase controlled multisource RF for both deep (up to 11 mm) non ablative RF and fractional RF skin resurfacing on the same treatment device. Study Design/Materials and Methods: Ten subjects with atrophic acne scars were enrolled in the study. Patients were photographed using standardized methods. In each treatment session, each patient received a full face 3DEEP non ablative skin tightening treatment followed by a Fractional skin resurfacing treatment. The treatment sessions were repeated once a month to a total of up to 4 treatments. Results: All subjects experienced mild-moderate edema and erythema as an immediate response to treatment. Edema resolved after up to three hours post treatment and erythema lasted up to 2 days. Micro ablative crusts were formed 1 - 2 days post treatments and lasted up to 5 days on facial areas. Patients' photographs—before each treatment session and 1 and 3 months after the last session—were graded according to the accepted Cosmetic Improvement Scale. All patients obtained significant skin improvement. Seventy percent of patients had 50% - 75% improvement one month after the third treatment session while the other thirty percent experienced a 25% - 50%. Discussion and Conclusions: The presented results describe for the first time a new treatment system (EndyMed PROTM) that allows both deep non ablative RF delivery and Fractional skin resurfacing on the same treatment platform. This work shows the synergy of combining these two applications for the improvement of acne scars, as well as for some secondary possible pigmentation and vascular improvement.

Abdominal and pelvic adhesions: Possible role of leiomyomas and skin scar anomaly in profiling high risk patients

Background and aims: Adhesions can cause important morbidity including abdominal and pelvic pain, intestinal obstructions, and infertility. When adhesions are formed, there is no efficient method, nowadays, to resolve them, thus the reduction of their prevalence relies on the prevention. Profiling high risk patients for abdominal and pelvic adhesions (APA) is an important step to this prevention. The risk factors of adhesions in our institution, the association between APA, leiomyomas and skin scar anomaly (SSA) were investigated. Methods: A cross-sectional study was conducted from March 1st to June 30th 2013 including patients who underwent laparotomy or laparoscopy. Patients’ characteristics, presence of a SSA and leiomyomas, as related to adhesions, were analyzed. Student’s t, Pearson’s Khi-square, Fisher’s Exact, Mann-Whitney tests and logistic regression were used. P values < 0.05 were considered statistically significant. Results: The frequency of adhesions was 41.74%. Patients had a mean age of 32.69 ± 8.94 years. Those with a previous abdominal surgery (PAS), SSA and leiomyomas had respectively 12 times [OR: 11.98, CI95 (4.63 - 30.97)], 3 times [OR: 2.79, CI95 (1.16 - 6.71) and 2.5 times [(OR: 2.49, CI95 (1.07 - 5.78)] more adhesions. In logistic regression, a PAS and leiomyomas remained associated significantly to adhesions with p = 0.000 and p = 0.037 respectively. Conclusion: In peritoneal adhesions, leiomyomas and SSA are other factors that may allow a cautious selection of high risk patients who must benefit from particular attention during surgery. Further well designed studies are necessary to investigate the accurate clinical relation among those three conditions.

Expression of MMP-1 in the Scar Tissue of Skin and Oral Mucosa

[Objectives] To investigate expression of MMP-1 in the scar tissue of skin and oral mucosa,and to explore if there is the significance of MMP-1 in the scar of skin and oral mucosa.[Methods]All samples were collected from surgical postoperative soft tissue from Department of Oral and Maxillofacial Surgery and Plastic Surgery in the Affiliated Qingdao Hiser Medical Center of Qingdao University Medical College,including 22 samples of dermal scar tissue,20 samples of normal skin tissue,and 13 samples of oral mucosal scar tissue,and 20 samples of normal oral mucosal tissue. HE staining was used to observe the morphology and collagen arrangement of fibroblasts in the scar tissue,the expression of MMP-1 in different tissue was observed by immunohistchemical staining. [Results] The positive expression rates of MMP-1 in skin scar tissue,oral mucousal scar tissue,normal skin tissue and normal mucosal tissue were 27. 27%,69. 23%,5. 00%,10. 00%. Comparison of positive expression of MMP-1 in skin scar tissue and oral mucosal scar tissue: the positive expression rate of MMP-1 in oral mucosal scar tissue was higher than that of MMP-1 in skin scar tissue,and the statistically significant difference was found between them( P < 0. 05).Comparison of positive expression of MMP-1 in skin scar tissue and normal skin tissue: the positive expression in skin scar tissue was higher than that in normal skin,and the statistically significant difference was found between them( P < 0. 05). Comparison of positive expression of MMP-1 in oral mucosal scar tissue and normal oral mucosal tissue: the positive expression rate of MMP-1 in oral mucosal scar tissue was higher than that in normal mucosal tissue,and the statistically significant difference was found between them( P < 0. 05). Comparison of positive expression of MMP-1 in normal oral mucosal tissue and normal skin tissue: the positive expression rate of MMP-1 in oral mucosal scar tissue was higher than that in normal mucosal tissue,and there was no statistically significant difference between them( P > 0. 05). [Conclusions] The positive expression of MMP-1 was different from that in the scar tissue of the oral mucosa,indicating that MMP-1 might be related to the severity of scar formation in different tissues.

The therapeutic effect of expanded scalp flaps pedicled with the superficial temporal vessel for the reconstruction of the large facial skin scar

Objective To investigate the therapeutic effect of expanded scalp flaps pedicled with superficial temporal vessel in the repair of facial skin scars.Methods From May 2017 to October 2018,4 patients with facial skin scars were treated with expanded scalp flaps pedicled with superficial temporal vessels and laser hair removal.All patients were followed up for at least 6 to 12 months.Results The flaps of all 4 patients survived well,and the color,texture and thickness of the flaps matched well with the surrounding skin tissue.Conclusion Expanded scalp flaps pedicled with superficial temporal vessel is a good option for repairing facial skin scars,which is worthy of clinical application.

Correction of Scar Contracture Deformity of Dorsal Hand by Invisible Full-thickness Mesh Skin Graft

Objective To investigate the effect of invisible full-thickness mesh skin graft in the treatment of scar contracture deformity of the dorsal hand.Methods From January 2016 to February 2019,25 patients with cicatricial contracture deformity of dorsal hand admitted to our hospital underwent full thickness skin graft.During the operation,the scar healed completely and the superficial fascia remained intact.The wound surface was transplanted with invisible mesh full thickness skin graft.The survival of the skin graft and the recovery of hand function and appearance in the later period were observed after the operation.Results The skin grafts of 20 patients survived with high quality,3 cases had partial epidermis exfoliation,and 2 cases had partial epidermis scattered in blisters.After intensive dressing change,all wounds healed and no complications occurred after the operation.The hand function and appearance of the patients were obviously improved.Conclusion The application of full thickness skin graft to correct scar deformity has the advantages of good functional and appearance recovery and difficult postoperative contracture.Invisible full-thickness mesh skin graft is one of the ideal methods to correct scar contracture deformity of the dorsal hand.

Clinical Application of Direct Skin Grafting Repair in Popliteal Scar Contracture after Burn in Children

Objective To observe the clinical application of direct skin grafting in repairing popliteal scar contracture after burn in children.Methods From April 2017 to January 2019,30 children with popliteal scar contracture after burn were selected as the research objects.The scar status,knee joint function and quality of life of the patients before and after the operation were compared by direct skin grafting after medium thickness skin removal.Results 30 patients were treated with skin grafting to repair popliteal scar contracture,27 patients healed well,and the survival rate of skin grafting reached 90.00%.The scores of postoperative scar and knee joint function scale(WOMAC)were lower than those before the operation,and the scores of concise health status scale(SF-36)were higher than those before the operation,with statistical significance(P<0.05).Conclusion Scar contracture of popliteal fossa after burn in children can be repaired by direct skin grafting in the skin extraction area after medium thickness skin cutting,which can effectively improve scar condition,restore knee joint function and significantly improve quality of life.

Clinical observation of the effect of crystallitic dermabrasion on skin superficial scars

To oberserve the changes in histopathology and clinical effect after the treatment of superficial scars in human faces and exposed parts of human extremities with crystallitic dermabrasion.Methods The machine made in Italy can produce the high speed crystallite to the surface of the scar,resulting in the alveolate wounds.At the same time the crystolitic drill make the accidented scar smooth.Results Two thousands and five hundreds and thirty eight suffers were treated for 2～10 times.The appearance of the scars was improved.Six patients complicated with milium,Eleven got hypopigmentation,eight got hypomelanotation.Eighty percent patients of this groups got pigmentation after the treatment.This signs disappeared or improved after 2～6 months.Histopathology demonstrated the scar area became small,the fibroblasts increased remarkably and the collagenous fiber arranged regularly.The cells in the stratum spinosum proliferated actively.Conclusion Crystallitic dermabrasion is a simple and safe method for the treatment of skin superficial scars.5 refs,4 figs.

人工真皮联合自体瘢痕表皮移植修复大面积烧伤后期关节部位瘢痕畸形

背景:如何既为大面积深度烧伤患者瘢痕整形修复提供足够的皮源,又能避免术区创面瘢痕的再次增生,一直是烧伤与创面修复研究的重要课题。目的:观察人工真皮联合自体瘢痕表皮复合移植在大面积烧伤后瘢痕整复中的临床应用效果。方法:回顾性分析2021年1月至2023年1月在蚌埠医学院附属蚌埠第三人民医院接受手术治疗的大面积烧伤后瘢痕增生、挛缩畸形患者的病历资料,共纳入73例,按照治疗方法分为3组:A组(n=21)接受人工真皮联合自体瘢痕表皮移植治疗;B组(n=27)接受功能部位瘢痕松解后移植自体瘢痕表皮治疗;C组(n=25)接受功能部位瘢痕松解后移植自体中厚皮治疗。记录3组患者受皮区皮片存活及感染情况,受皮区及供皮区创面愈合时间;通过温哥华瘢痕量表(VSS)、日常生活活动能力(ADL)评定3组患者受皮区、供皮区瘢痕情况及受皮区功能恢复情况。结果与结论:①B组患者皮片感染率低于A、C组(P<0.05),皮片存活优级率高于A、C组(P<0.05);②A组患者受皮区创面完全愈合时间长于B、C组(P<0.05),C组患者受皮区创面完全愈合时间长于B组(P<0.05);C组患者供皮区完全愈合时间长于A、B组(P<0.05);③B组患者术后12个月受皮区温哥华瘢痕量表评分高于A、C组(P<0.05),C组患者术后6,12个月供皮区温哥华瘢痕量表评分高于A、B组(P<0.05);A、C组患者术后12个月日常生活活动能力量表评估优级高于B组(P<0.05);④结果显示,应用人工真皮与自体瘢痕表皮复合移植治疗大面积烧伤后瘢痕挛缩,既能达到与中厚皮移植同样的效果,又能避免供皮区术后瘢痕的再次增生,可缩短供皮区创面愈合时间,相较于单纯移植瘢痕表皮治疗有明显优势。

植皮手术联合瘢痕整形对烧伤后患者美容效果的影响

目的 探讨植皮手术联合瘢痕整形对烧伤后患者美容效果的影响。方法 选取80例深度烧伤后整形患者为研究对象,选择随机数字表法分为研究组和参照组,每组40例。研究组患者采用植皮手术联合瘢痕整形治疗,参照组患者采用单一植皮手术治疗。比较两组患者二次手术率及皮片成活率、瘢痕情况、术后瘢痕增生程度及瘢痕典型案例发生情况、满意度。结果 二次手术率比较,研究组(2.50%)显著低于参照组(25.00%)(P<0.05);皮片成活率比较,研究组(97.50%)显著高于参照组(65.00%)(P<0.05)。两组术前厚度、色泽、血管分布、柔软度评分比较无显著差异(P>0.05);两组术后厚度、色泽、血管分布、柔软度评分低于术前(P<0.05);研究组术后厚度、色泽、血管分布、柔软度评分分别为(1.98±0.11)、(1.11±0.08)、(1.12±0.28)、(1.34±0.32)分,低于参照组的(2.59±0.12)、(1.85±0.12)、(1.39±0.12)、(1.65±0.12)分(P<0.05)。术后瘢痕增生情况比较,研究组优于参照组(P<0.05);瘢痕典型案例发生率比较,研究组(0)显著低于参照组[15.00%(6/40)](P<0.05)。满意度比较,研究组(97.50%)显著高于参照组(75.00%)(P<0.05)。结论 深度烧伤后整形患者选择植皮手术联合瘢痕整形治疗方案,美容效果好,价值显著,可推广。

病理性瘢痕形成的细胞分子机制的研究进展

皮肤损伤在愈合后会形成纤维化组织,即瘢痕。其中的病理性瘢痕因其外观不佳及痛痒不适感,严重影响患者的生活质量。然而,目前病理性瘢痕的发病机制尚不完全明确,缺乏有效的动物模型及临床根治手段。本文回顾总结了病理性瘢痕免疫微环境中的细胞分子学机制与相互作用,旨在为病理性瘢痕诊断标志物与治疗靶点的研发以及组织工程构建的优化提供参考。

15G针头打孔自体中厚皮片对四肢深度烧伤患者的影响

目的:探讨15G针头打孔制备自体中厚皮片对四肢深度烧伤患者瘢痕愈合情况及肢体活动功能恢复的影响。方法:回顾性选取2021年1月—2023年5月于九江市第一人民医院就诊的60例四肢深度烧伤患者,依据所行移植手术方式不同分为研究组和对照组,每组30例,其中对照组仅予以常规中厚皮片加压移植治疗,研究组予以15G针头打孔制备自体中厚皮片加压移植治疗,两组均干预至出院,追踪随访6个月。比较两组术后瘢痕愈合情况、瘢痕评分、肢体活动功能、术后疼痛程度、生活质量,并统计术后并发症例数。结果:研究组瘢痕愈合时间、住院时间均较对照组短,移植成活率较对照组高,差异均有统计学意义(P<0.05)。术后6个月,研究组温哥华瘢痕评定量表(VSS)评分均低于对照组,Fugl-Meyer评分高于对照组,差异均有统计学意义(P<0.05);研究组术后1、2周视觉模拟法评分(VAS)评分均低于对照组,差异均有统计学意义(P<0.05);研究组健康调查简表(SF-36)各维度评分均高于对照组,差异均有统计学意义(P<0.05)。结论:15G针头打孔制备自体中厚皮片能明显促进四肢深度烧伤患者瘢痕愈合,改善瘢痕状态,同时帮助肢体活动功能恢复,减轻术后创面疼痛,提高生活质量水平。

SDF-1/CXCR4轴在皮肤及周围神经损伤修复中的研究进展

皮肤组织遭受损伤时,其损伤修复对于恢复皮肤的稳态非常重要,趋化因子SDF-1在此过程中起着非常关键的作用。本文对SDF-1/CXCR4轴在创面愈合、损伤处神经修复作用、创伤后瘢痕形成以及其对损伤部位神经疼痛的影响进行综述,为开发更有效的皮肤及周围神经损伤的治疗方法和策略提供指导。

精准脉冲光干预对面部外伤美容缝合术后早期瘢痕形成的影响

目的:探讨精准脉冲光(Delicatepulsedlight,DPL)干预对面部外伤美容缝合术后早期瘢痕形成的影响。方法:选择2021年4月-2021年10月就诊于笔者医院的380例面部软组织损伤患者临床资料进行回顾性分析,将患者按照治疗方式不同分为激光组(280例)和对照组(100例)。激光组清创后采用整形美容缝合联合DPL早期干预(伤口愈合拆线后1周)治疗;对照组清创后仅进行整形美容缝合治疗。术后3~6个月瘢痕稳定时,评估患者瘢痕及满意度。结果:术后3~6个月瘢痕稳定时,激光组温哥华瘢痕量表评分低于对照组(P<0.05),激光组患者及医师满意度均高于对照组(P<0.05)。结论:面部软组织损伤后,通过整形美容缝合联合DPL激光早期干预能减少瘢痕形成,提高患者及医师满意度,疗效确切。

脱细胞皮肤基质/聚氨酯混纺纤维支架促进大鼠皮肤缺损的修复

背景:研究证实,将脱细胞基质与聚合物进行混合纺丝不仅可改善纤维的结构性质,还可保存脱细胞基质的生物学活性,但是目前将聚氨酯与脱细胞皮肤基质进行静电纺丝制备皮肤组织工程支架还没有相关报道。目的:观察脱细胞皮肤基质/聚氨酯混纺纤维支架对大鼠皮肤缺损的修复作用。方法:利用静电纺丝技术分别制备聚氨酯静电纺丝纤维支架和脱细胞皮肤基质/聚氨酯混纺纤维支架。扫描电镜下观察纤维结构;将大鼠脂肪间充质干细胞分别接种于两组支架上,扫描电镜下观察支架上的细胞形态。取10只SD大鼠,在每只大鼠背部制作3个1 cm×1 cm的全层皮肤缺损,其中2处缺损分别植入聚氨酯静电纺丝纤维支架(对照组)、脱细胞皮肤基质/聚氨酯混纺纤维支架(实验组),剩余缺损处不植入任何材料(空白对照组)。术后第1,2,3周,观察皮肤创面愈合情况;植入后第3周,进行创面苏木精-伊红染色,计算创面瘢痕面积。结果与结论:①扫描电镜下可见两种静电纺丝纤维均为网状结构,并且大鼠脂肪间充质干细胞在两种支架上沿纤维附着,黏附良好。②随着术后时间的延长,各组皮肤创面逐渐愈合,至术后第3周,实验组、对照组皮肤创面基本愈合,空白对照组创面可见小溃疡形成。皮肤创面苏木精-伊红染色显示,对照组、实验组创面表皮覆盖基本完整,真皮层内可见成纤维细胞长入和炎症细胞浸润,并且实验组创面胶原纤维较为丰富、排列规则有序,与表皮面基本平行;空白对照组创面表皮仍有缺损。实验组创面瘢痕面积小于其他两组(P<0.05,P<0.01)。③结果表明,脱细胞皮肤基质/聚氨酯混纺纤维支架可以有效修复大鼠全层皮肤缺损、改善创面瘢痕形成。

Understanding wound healing in obesity

Obesity has become more prevalent in the global population.It is associated with the development of several diseases including diabetes mellitus,coronary heart disease,and metabolic syndrome.There are a multitude of factors impacted by obesity that may contribute to poor wound healing outcomes.With millions worldwide classified as obese,it is imperative to understand wound healing in these patients.Despite advances in the understanding of wound healing in both healthy and diabetic populations,much is unknown about wound healing in obese patients.This review examines the impact of obesity on wound healing and several animal models that may be used to broaden our understanding in this area.As a growing portion of the population identifies as obese,understanding the underlying mechanisms and how to overcome poor wound healing is of the utmost importance.

不同部位烧伤瘢痕癌的外科治疗策略

目的探讨不同部位烧伤瘢痕癌的创面修复策略。方法回顾性分析我科2013年1月至2023年1月收治的38例烧伤瘢痕癌患者的临床资料,总结临床特点、影像学、病理学诊断评估和手术方法,观察创面愈合情况、肿瘤复发率和存活率。结果38例患者中,男23例,女15例,平均年龄(53.63±9.74)岁,其中火焰烧伤32例,热水烫伤6例,癌变潜伏期(35.65±14.60)年。病变位于头部7例、下肢18例、上肢8例、躯干3例、面部2例。2例为基底细胞癌(浅表型1例,浸润型1例,病理分级:中分化1例,高分化1例),36例为鳞状细胞癌(病理分级:低分化2例,中分化10例,高分化24例)。35例患者接受手术治疗,其中6例截肢;另3例放弃治疗。创面修复方案包括植皮手术19例、局部皮瓣4例和游离皮瓣转移6例。中位随访时间2(2,3)年,3例放弃治疗的患者在随访期间死亡,余35例手术的患者中30例创面愈合良好且肿瘤未复发,5例肿瘤复发(3例再次接受手术治疗,死亡1例,存活2例;2例保守治疗,死亡1例,存活1例)。结论针对烧伤瘢痕癌的创面修复策略应根据肿瘤部位、性质、范围和患者全身条件进行个性化制定,早期切除病变是治疗的关键。植皮、皮瓣转移、游离皮瓣移植和截肢等方法可用于修复烧伤瘢痕癌的创面。手术治疗能够促进创面的愈合,但肿瘤复发仍然是一个重要的问题,需要进一步研究和探索。

以反复破溃化脓和疤痕为表现的铜绿假单胞菌皮肤感染一例

患者,女,28岁。左小腿反复破溃化脓和疤痕6个月余。皮肤科检查:左小腿外侧可见一约5 cm×6 cm红色斑块,部分呈凹陷性疤痕,部分隆起,质地偏软,可挤出少许黄色分泌物。新鲜组织mNGS检测提示铜绿假单胞菌,口服头孢克肟胶囊0.2 g,每日2次,治疗2周后,原有皮疹大部分变平,未见脓性分泌物渗出,2个月随访未见复发。

无创皮肤吻合器联合心形缝合皮下脂肪对腹部瘢痕的影响

目的:探讨无创皮肤吻合器联合心形缝合皮下脂肪对腹部瘢痕的影响。方法:回顾性分析2021年1月—2022年9月于新余市妇幼保健院行剖宫产手术的120例患者的病历资料,将接受无创皮肤吻合器联合心形缝合的60例患者纳入A组,将接受无创皮肤吻合器联合传统美容缝合的60例患者纳入B组,两组出院后均随访6个月。比较两组切口缝合时间、切口愈合时间及住院时间,术后24 h、72 h、7 d切口疼痛[视觉模拟评分法(VAS)],术后1个月切口愈合情况、切口并发症发生率,术后6个月切口瘢痕情况[温哥华瘢痕评定量表(VSS)]、缝合效果满意度。结果:两组切口缝合时间差异无统计学意义(P>0.05),A组切口愈合时间与住院时间均短于B组,差异均有统计学意义(P<0.05);两组术后24 h、72 h VAS评分差异均无统计学意义(P>0.05),A组术后7 d VAS评分低于B组,差异有统计学意义(P<0.05);术后1个月,A组伤口愈合等级优于B组,A组切口并发症总发生率低于B组,差异均有统计学意义(P<0.05);术后6个月,A组VSS评分低于B组,A组缝合效果满意度高于B组,差异均有统计学意义(P<0.05)。结论:无创皮肤吻合器联合心形缝合皮下脂肪在剖宫产患者中应用价值高,能有效促进术后患者腹部切口愈合,减少术后疼痛,降低切口并发症发生及瘢痕增生风险,并获得更高的患者满意度。

皮肤软组织扩张术与复合皮移植术用于烧伤整形患者的效果比较

目的:比较皮肤软组织扩张术与复合皮移植术用于烧伤整形患者的效果。方法:选取2019年12月至2022年12月该院收治的68例烧伤整形患者进行前瞻性研究,按随机数字表法将其分为观察组和对照组各34例。观察组采取皮肤软组织扩张术治疗,对照组采取复合皮移植术治疗。比较两组临床疗效、术后数字分级评分法(NRS)评分、创面愈合时间、血运恢复时间、手术前后生命质量[简明烧伤健康量表(BSHS-B)]、瘢痕评分[温哥华瘢痕评定量表(VSS)]、血清炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-1α(IL-1α)]水平,以及并发症发生率。结果:观察组治疗总有效率为94.12%(32/34),高于对照组的76.47%(26/34),差异有统计学意义(P<0.05);观察组术后NRS、VSS评分及血清TNF-α、IL-1α水平均低于对照组,创面愈合时间、血运恢复时间均短于对照组,BSHS-B评分高于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为8.82%(3/34),低于对照组的29.41%(10/34),差异有统计学意义(P<0.05)。结论:皮肤软组织扩张术用于烧伤整形患者效果优于复合皮移植术,可减轻术后疼痛和炎症反应,抑制瘢痕形成,缩短创面愈合和血运恢复时间,降低并发症发生率,提高患者生命质量。