目的探讨系统化孕前保健对备孕妇女孕前身体质量指数(body mass index,BMI)的影响。方法选取2017年1月—2019年6月在本院参与孕前管理的196例备孕妇女,随机分为两组各98例,对照组给予常规保健,观察组给予系统保健,对比两组备孕妇女孕前...目的探讨系统化孕前保健对备孕妇女孕前身体质量指数(body mass index,BMI)的影响。方法选取2017年1月—2019年6月在本院参与孕前管理的196例备孕妇女,随机分为两组各98例,对照组给予常规保健,观察组给予系统保健,对比两组备孕妇女孕前身体质量指数的变化。结果组内对比,观察组干预前后的BMI正常者人数差异具有统计学意义(P<0.05);组间对比,干预后观察组BMI正常者明显多于对照组(P<0.05),超重者明显少于对照组(P<0.05)。结论系统化孕前保健能有效改善备孕妇女孕前BMI。展开更多
Objective To explore the interactions between pre-pregnancy body mass index(BMI) and age on offspring neuropsychological development from 1 to 24 months in China.Methods In this birth cohort study, a total of 2,253 mo...Objective To explore the interactions between pre-pregnancy body mass index(BMI) and age on offspring neuropsychological development from 1 to 24 months in China.Methods In this birth cohort study, a total of 2,253 mother-child pairs were enrolled in Tianjin, China,between July 2015 and May 2018. The China Developmental Scale for Children was used to assess developmental quotient(DQ) of children aged from 1 to 24 months.Results Mixed-models analysis revealed significant age × pre-pregnancy BMI interactions for total DQ and five neurobehavioral domains(gross motor, fine motor, adaptive, language, and social;P < 0.001).Age × pre-pregnancy BMI ≥ 25 kg/m^2 was associated with a negative effect on total DQ and five neurobehavioral domains, as compared to pre-pregnancy BMI < 25 kg/m^2(P < 0.01). Multiple comparisons showed pre-pregnancy BMI ≥ 25 kg/m^2 of mothers had a positive effect on child total DQ at the age of 1 month but a negative effect at 24 months(P < 0.05).Conclusions This study supported the age × pre-pregnancy BMI interaction on offspring neuropsychological development. It also revealed a short-term positive impact of high pre-pregnancy BMI on neuropsychological development at 1 month of age, but a long-term negative effect(from 1 to24 months).展开更多
Background: Hypertensive disorders are common causes of maternal and fetal mortality and morbidity. Objective: This study aimed to examine the prognostic value of risk assessment at level of antenatal care clinics in ...Background: Hypertensive disorders are common causes of maternal and fetal mortality and morbidity. Objective: This study aimed to examine the prognostic value of risk assessment at level of antenatal care clinics in predicting pre-eclampsia at a high altitude (3133 m above sea level). Methods: This cross-sectional study, carried out in Abha Maternity and Pediatric Hospital (AMPH), Saudi Arabia, between January and June 2013, included 176 patients (88 pre-eclamptic women and 88 with normal pregnancies). Patient data including age, parity, blood pressure, body mass index, and complete blood count components were recorded. Results: Physical examination of systolic blood pressure, diastolic blood pressure and BMI between two groups showed high statistical significance with a P value of P value of P = 0.291). Mean plasma hematocrit levels in the study and the control groups were 38.49% ± 4.32% and 37.92% ± 7.04%, respectively;this was not found to be statistically significant (P = 0.518). Although there was an increase in laboratory blood tests of maternal hematocrit and hemoglobin levels, both parameters failed to show any statistical significance. Conclusion: Risk assessment at level of antenatal care clinics can be considered as valuable prognostic tool for prediction of preeclampsia. Any pregnant lady with abnormal physical examination findings of: BMI, systolic and diastolic blood pressure and obstetric history following risk assessment in antenatal care clinics should be observed for possibility of pre-eclampsia.展开更多
文摘目的探讨系统化孕前保健对备孕妇女孕前身体质量指数(body mass index,BMI)的影响。方法选取2017年1月—2019年6月在本院参与孕前管理的196例备孕妇女,随机分为两组各98例,对照组给予常规保健,观察组给予系统保健,对比两组备孕妇女孕前身体质量指数的变化。结果组内对比,观察组干预前后的BMI正常者人数差异具有统计学意义(P<0.05);组间对比,干预后观察组BMI正常者明显多于对照组(P<0.05),超重者明显少于对照组(P<0.05)。结论系统化孕前保健能有效改善备孕妇女孕前BMI。
基金supported by a grant from the National Natural Science Foundation of China [No.81472967 and No.81602849]Young Elite Scientists Sponsorship Program by CAST [No.2017QNRC001]
文摘Objective To explore the interactions between pre-pregnancy body mass index(BMI) and age on offspring neuropsychological development from 1 to 24 months in China.Methods In this birth cohort study, a total of 2,253 mother-child pairs were enrolled in Tianjin, China,between July 2015 and May 2018. The China Developmental Scale for Children was used to assess developmental quotient(DQ) of children aged from 1 to 24 months.Results Mixed-models analysis revealed significant age × pre-pregnancy BMI interactions for total DQ and five neurobehavioral domains(gross motor, fine motor, adaptive, language, and social;P < 0.001).Age × pre-pregnancy BMI ≥ 25 kg/m^2 was associated with a negative effect on total DQ and five neurobehavioral domains, as compared to pre-pregnancy BMI < 25 kg/m^2(P < 0.01). Multiple comparisons showed pre-pregnancy BMI ≥ 25 kg/m^2 of mothers had a positive effect on child total DQ at the age of 1 month but a negative effect at 24 months(P < 0.05).Conclusions This study supported the age × pre-pregnancy BMI interaction on offspring neuropsychological development. It also revealed a short-term positive impact of high pre-pregnancy BMI on neuropsychological development at 1 month of age, but a long-term negative effect(from 1 to24 months).
文摘Background: Hypertensive disorders are common causes of maternal and fetal mortality and morbidity. Objective: This study aimed to examine the prognostic value of risk assessment at level of antenatal care clinics in predicting pre-eclampsia at a high altitude (3133 m above sea level). Methods: This cross-sectional study, carried out in Abha Maternity and Pediatric Hospital (AMPH), Saudi Arabia, between January and June 2013, included 176 patients (88 pre-eclamptic women and 88 with normal pregnancies). Patient data including age, parity, blood pressure, body mass index, and complete blood count components were recorded. Results: Physical examination of systolic blood pressure, diastolic blood pressure and BMI between two groups showed high statistical significance with a P value of P value of P = 0.291). Mean plasma hematocrit levels in the study and the control groups were 38.49% ± 4.32% and 37.92% ± 7.04%, respectively;this was not found to be statistically significant (P = 0.518). Although there was an increase in laboratory blood tests of maternal hematocrit and hemoglobin levels, both parameters failed to show any statistical significance. Conclusion: Risk assessment at level of antenatal care clinics can be considered as valuable prognostic tool for prediction of preeclampsia. Any pregnant lady with abnormal physical examination findings of: BMI, systolic and diastolic blood pressure and obstetric history following risk assessment in antenatal care clinics should be observed for possibility of pre-eclampsia.