Correlation Study of Neurotransmitter and Immune Levels in Pre-Hospital Emergency Nurses with Post-Traumatic Stress Disorder

Objective: To investigate the occurrence of PTSD in pre-hospital emergency nurses and its related factors, and to compare the differences of neurotransmitter and immune-related factors between pre-hospital emergency nurses who experienced traumatic events and those who did not develop PTSD and healthy people. How: Post-traumatic Stress Disorder Self-Rating Scale (PCL-C) tests were performed on pre-hospital emergency nurses in PTSD group, non-PTSD group and healthy control group, and the plasma monoamine neurotransmitters and serum cytokines were determined by double-antibody sandwich ABC-ELISA assay using enzyme-linked adsorption kit provided by Shanghai Xitang Biotechnology Co., Ltd. Results: 1) There were statistically significant differences in PCL-C scores between PTSD group, non-PTSD group and healthy group (p α between PTSD group, non-PTSD group and healthy group (p Conclusion: Pre-hospital emergency nurses should have early psychological intervention and guidance to reduce the occurrence of PTSD in emergency and emergency nurses.

82例门诊HIV感染者/AIDS患者人口学特征分析

目的:了解皮肤性病就诊者中HIV感染者/AIDS患者的人口学特征及发现方式,为制定HIV筛查策略提供参考依据。方法:收集某皮肤病专科医院2018年3月至2023年10月上报的82例HIV感染者/AIDS患者信息,对其人口学特征、伴发疾病和发现方式等进行频数和一般描述性统计分析。结果:82例HIV感染者/AIDS患者中,男80例,女2例,年龄17~71岁,平均(37.40±12.28)岁,单身55例,大专及以上学历26例。本省其它地市48例,其他省12例。76例有男男性接触史,56例因皮肤症状就诊发现,26例因高危性行为或曾患性病主动查体发现,71例在性病门诊发现。结论:皮肤性病就诊者中HIV感染/AIDS患者具有包括多数为男性、性活跃人群、单身、文化程度较低、外地人为主等特征,有高风险性行为和皮肤性病症状的就诊者应有针对性地加强筛查。

A Collocation Technique via Pell-Lucas Polynomials to Solve Fractional Differential EquationModel for HIV/AIDS with Treatment Compartment

In this study,a numerical method based on the Pell-Lucas polynomials(PLPs)is developed to solve the fractional order HIV/AIDS epidemic model with a treatment compartment.The HIV/AIDS mathematical model with a treatment compartment is divided into five classes,namely,susceptible patients(S),HIV-positive individuals(I),individuals with full-blown AIDS but not receiving ARV treatment(A),individuals being treated(T),and individuals who have changed their sexual habits sufficiently(R).According to the method,by utilizing the PLPs and the collocation points,we convert the fractional order HIV/AIDS epidemic model with a treatment compartment into a nonlinear system of the algebraic equations.Also,the error analysis is presented for the Pell-Lucas approximation method.The aim of this study is to observe the behavior of five populations after 200 days when drug treatment is applied to HIV-infectious and full-blown AIDS people.To demonstrate the usefulness of this method,the applications are made on the numerical example with the help of MATLAB.In addition,four cases of the fractional order derivative(p=1,p=0.95,p=0.9,p=0.85)are examined in the range[0,200].Owing to applications,we figured out that the outcomes have quite decent errors.Also,we understand that the errors decrease when the value of N increases.The figures in this study are created in MATLAB.The outcomes indicate that the presented method is reasonably sufficient and correct.

Systemic analysis of pre-hospital trauma emergency treatment in Zhengzhou

Objective: To analyze the data of pre-hospital emergency treatment in zhengzhou from 2007 to 2016, and evaluate the current situation of pre-hospital trauma emergency treatment, in order to provide a scientific basis for effective use of first aid resources and enhance success rate of trauma emergency treatment. Methods: Retrospective analysis was conducted based on pre-hospital emergency resources of Zhengzhou Emergency Medical Rescue Center from 2007 to 2016. Results: The total number of pre-hospital emergency treatment cases was 9305687 from 2007 to 2016 in Zhengzhou, of which 418882 were trauma cases. The top five causes of injury were traffic accident injury, cutting injury, beating injury, crushing injury and falling injury. The top five emergency treatments used were oxygen, hemostasis, dressing and fixation, fluid supplementation, analgesics and sputum aspiration. According to different directions of diagnosis, the pre-hospital emergency patients were divided into four groups:emergency treatment group, emergency observation group, admission to general ward group and admission to ICU group. There was no statistical difference in the ages among the four groups (P>0.05). There were significantly statistical differences in gender composition among the four groups, with more males than females (P<0.01). Significant statistical differences also showed in CRAMS scores among the four groups (P<0.01). Before and after the training of primary trauma care, there was no significant difference in the constituent ratio of the trauma (P>0.05), but the mortality of the trauma, the average arrival time, and the mean treatment time were significantly different (P<0.01). Conclusions: The number of pre-hospital emergency trauma patients increased year by year, but the constituent ratio changed little. CRAMS score is important for the patients triage. Through the training of primary trauma care, the constituent ratio of death was reduced, and the average treatment time was shortened.

Clinical Research of Pre-Hospital Emergency Care, Nursing, Infection Prevention and Control for Senile Osteoporotic Vertebral Compression Fracture during Epidemic Period

Background: Novel coronavirus pneumonia (NCP) and osteoporotic vertebral compression fractures (OVCF) are the high incidences of diseases in the elderly. During the epidemic period, if not treated in time, the complications are high and the mortality is high. If we do not pay attention to infection prevention and control in pre-hospital emergency care, it will lead to the first time infection of medical staff and in-hospital cross infection in emergency outpatient receiving area. The correct consideration of both and the establishment of perfect pre-hospital emergency treatment and infection prevention and control synchronous strategy is an important premise to ensure the stable, orderly and safe medical treatment. Objective: To explore the effect of synchronous implementation of pre-hospital emergency care, nursing and infection pre-vention and control for senile OVCF during the epidemic. In order to improve the efficiency of pre-hospital emergency care and prevent the spread of infection. Method: A total of 92 elderly patients with OVCF who received pre-hospital treatment in 18 hospitals in Zhangjiakou City during the epidemic prevention and control period from January 2020 to November 2022 and met the inclusion criteria were selected as research objects, including 24 males and 68 females, aged 65 - 82 (74.2 ± 2.2) years. All patients were associated with concomitant injuries and underlying diseases. All patients in this group underwent predictive pre-hospital rescue and infection prevention and control procedures. Results: All the 92 elderly patients with OVCF received timely pre-hospital treatment during the epidemic period, and no aggravation occurred of the 92 patients, 35 were in the high risk area, 10 were in the medium risk area, and 47 were in the low risk area. Exclude OVCF for NCP Patients were treated according to the conventional diagnosis and treatment principles. Suspected and confirmed cases are transferred to designated surgical hospitals for treatment. All patients were followed up 3 months, 6 months and 12 months after treatment. There was no death rate, high satisfaction of pre-hospital first aid, high diagnostic accuracy, and good curative effect. None of the rescue personnel had any infection rate, and no hospital infection transmission and nosocomial cross infection occurred. Conclusion: It is the first step to safely treat patients and prevent cross infection to establish a perfect synchronous strategy of pre-hospital first aid and infection prevention and control.

Research on subsidence method aided by water injection and its engineering application for the north anchor of Taizhou Bridge

The north anchorage caisson of Taizhou Bridge encountered some difficulties during the sinking process for the large sidewall frictional resistances. To solve this problem, a new concept and method called subsidence method aided by water injection is proposed. Numeral analysis is adopted to simulate the effects of this method for the north anchor of Taizhou Bridge, which confirmed the feasibility and validity. Finally, the method is applied to the north anchor caisson during the caisson sinking procedure and helps the caisson sink and embed to the designed position smoothly.

复合助剂对低温喷雾干燥蓝靛果粉理化性质的影响

为保证低温喷雾干燥后蓝靛果粉品质,采用黄金分割法研究复合助剂(麦芽糊精、β-环糊精和乳清蛋白)对喷雾干燥蓝靛果粉理化性质的影响,分析低温进风温度(50~90℃)对蓝靛果粉花青素保留率、集粉率和含水率的影响规律。结果表明,在麦芽糊精、β-环糊精的质量比例为85.4%、14.6%时,集粉率高达37.96%;随进料溶液中麦芽糊精质量比例增加,蓝靛果粉玻璃化转变温度、水溶性指数、堆积密度、亮度L^(*)值、红度a^(*)值和色差值ΔE呈增加趋势,含水率、花青素含量和黄度b^(*)值呈下降趋势;在麦芽糊精、β-环糊精和乳清蛋白质量比例为72.9%、12.5%、14.6%时,集粉率达到最高(40.11%);随料液中乳清蛋白质量比例增加,蓝靛果粉含水率、花青素含量呈上升趋势,其玻璃化转变温度、水溶性指数、亮度L^(*)值、红度a^(*)值、黄度b^(*)值和色差值ΔE等指标呈下降趋势;复合助剂显著提高蓝靛果粉集粉率(P<0.05),对其中的花青素起到较强保护作用,其含水率、水溶性指数、堆积密度等理化指标均接近于最优水平。低温喷雾干燥研究发现,随进风温度上升,集粉率和含水率呈负相关,在进风温度90℃时,集粉率最高的配方中可实现较高花青素保留率(89.94%)。低频核磁共振波谱以及质子密度图像信息分析表明,加入的助剂与蓝靛果果汁中水分通过氢键、静电结合力和疏水作用等分子间作用力,形成稳定性高水合物、增强液滴聚结抵抗力,提高料液玻璃态转换温度,从而实现高集粉率和高花青素保留率的蓝靛果果粉低温喷雾干燥;红外光谱分析表明,复合助剂可在蓝靛果果粉中形成分子间氢键,并对花青素等活性物质进行固定包埋保护。研究结果可为蓝靛果粉喷雾干燥加工生产提供理论支撑和参考依据。

TRIZ裁剪方法研究进展综述

裁剪作为TRIZ中提高理想化程度的创新方法,目前已经应用在产品创新设计领域,可有效解决产品创新问题。为更好地进行裁剪方法研究,对国内外主要的相关文献进行研究和分析,系统梳理了裁剪相关概念及主要研究内容。首先,介绍裁剪定义、裁剪流程等相关概念;其次,基于国内外相关文献关键词共现图谱,结合文献具体内容,总结出现有裁剪研究主要集中在:对裁剪组件选择,确定裁剪组件后搜索资源进行有用功能分配、裁剪流程优化、裁剪方法的软件实现以及裁剪方法的应用;最后,提出现有裁剪方法存在的问题与不足,为未来进行裁剪方法研究和应用提供参考。

高校家庭经济困难学生精准资助育人机制研究

为全方位提升高校精准资助育人效能,减轻家庭经济困难学生的经济压力,推动教育公平,通过资助对象的精准把握、资助力度的精准控制、资助方式的精准调节,高质量完成高校资助育人的目标任务。文章立足家庭经济困难学生资助现状,着眼精准资助育人总体要求,借鉴过往经验做法,梳理思路,创新方法,健全机制,推动保障性资助向发展型资助的转型,更好地促进家庭经济困难学生的健康成长成才。

DRG支付方式带给中国医疗服务体系发展的机遇与挑战分析

DRG支付方式是中国医疗服务体系高质量发展的机遇,体现在DRG是促进医疗管理和绩效管理升级的有效工具,DRG支付方式改革将促进医院病案质量的提升、促进合理用药和临床药学的发展、推动医用耗材的精细化管理、促进检验与临床诊疗的更好结合及医疗服务效率的提高、医疗服务体系的重塑。同时,DRG的科学设置与执行能力、门诊统筹的建立对医保支付管理的要求、基层医务人员的素质对建立基层首诊与转诊制度的阻碍、门诊共济制度下的基层与医院门诊服务支付方式等问题,是对支付方式改革和中国医疗服务体系的挑战。中国医疗服务提供体系未来的变化趋势为三级医疗机构规模的压缩和基层社区守门人制度的建立,影响改革的重要因素之一是医疗服务价格机制改革。

猪伪狂犬病毒荧光重组酶介导核酸扩增快速检测方法的建立与应用

【目的】基于荧光重组酶介导核酸扩增(Recombinase-aided amplification,RAA)技术,建立一种猪伪狂犬病毒(Porcine pseudorabies virus,PRV)快速检测方法。【方法】根据PRV gE基因序列,设计特异性引物及探针,优化扩增体系,建立PRV荧光重组酶介导核酸扩增检测方法,检验其特异性、敏感性和重复性,应用该方法对临床样品进行检测。【结果】该方法在43℃恒温反应23 min即可完成PRV核酸扩增,最低检出限为111 copies·μL^(-1);与猪繁殖与呼吸综合征病毒(Porcine reproductive and respiratory syndrome virus,PRRSV)、猪流行性腹泻病毒(Porcine epidemicdiarrheavirus,PEDV)、猪轮状病毒(Porcinerotavirus,PoRV)、猪传染性胃肠炎病毒(Transmissible gastroenteritis virus,TGEV)、猪圆环病毒2型(Porcine circovirus 2,PCV2)、猪圆环病毒3型(Porcine circovirus 3,PCV3)均无交叉反应。重复性试验显示,组内和组间变异系数均小于5%;40份临床样品检测结果显示PRV阳性率为15%(6/40),检测结果与常规聚合酶链式反应(PCR)一致。【结论】成功建立了简便快速、高效准确的PRV实时荧光RAA检测方法,为PRV的快速检测和流行病学调查提供了新的检测手段。

HIV/AIDS患者中医四诊信息的主成分分析

目的:应用主成分分析方法对HIV/AIDS患者中医四诊信息进行分析。方法:采用多阶段整群抽样的方法,抽取中部某省的1279例HIV/AIDS患者,对调查对象中医四诊信息指标进行主成分分析。结果:主成分分析将中医四诊信息中33个指标成功降维,综合成16个主成分;其中第1主成分贡献率为20.049%,前16个主成分的累积贡献率为70.655%。结论:主成分分析可以对中医四诊指标进行降维、综合,有良好的应用前景。

心血管内科低年资护士临床急救能力培训方案的构建研究

目的构建心血管内科低年资护士临床急救能力培训方案。方法以胜任力冰山模型为理论依据,基于文献回顾法、问卷调查及半结构访谈法拟订心血管内科低年资护士临床急救能力培训方案初稿,通过Delphi法对28名心血管内科护理专家进行2轮专家函询,构建心血管内科低年资护士临床急救能力培训方案。结果2轮函询专家积极系数均为100%,专家的权威系数为0.847,肯德尔协调系数分别为0.274和0.395(P<0.05)。构建的心血管内科低年资护士临床急救能力培训方案包括培训模块(理论知识、操作技能、应急抢救、沟通协调、职业特质)、培训内容、培训方式、学时安排、培训师资、考核方式。结论构建的心血管内科低年资护士临床急救能力培训方案具有科学性和可靠性,为各医院心血管内科低年资护士临床急救能力规范化培训提供参考依据和实践思路。

ROBUST ACOUSTIC SOURCE LOCALIZATION FOR DIGITAL HEARING AIDS IN NOISE AND REVERBERANT ENVIRONMENT

A new method in digital hearing aids to adaptively localize the speech source in noise and reverberant environment is proposed. Based on the room reverberant model and the multichannel adaptive eigenvalue decomposition （MCAED） algorithm, the proposed method can iteratively estimate impulse response coefficients between the speech source and microphones by the adaptive subgradient projection method. Then, it acquires the time delays of microphone pairs, and calculates the source position by the geometric method. Compared with the traditional normal least mean square （NLMS） algorithm, the adaptive subgradient projection method achieves faster and more accurate convergence in a low signal-to-noise ratio （SNR） environment. Simulations for glasses digital hearing aids with four-component square array demonstrate the robust performance of the proposed method.

基于德尔菲法的《脑卒中“病脉证并治”临床辅助决策方案》条目筛选

目的对《脑卒中“病脉证并治”临床辅助决策方案》进行条目筛选,为方案制定和完善提供参考。方法采用德尔菲法,通过问卷星平台于2022年7、8月分别向全国60位脑病学或神经病学方向专家发放两轮问卷,对方案的病名概述、病因病机、证候特点、治则治法、代表方、针灸及其他疗法与预防调护具体条目问卷结果进行统计学分析。结果两轮调查分别回收42、50份有效问卷。专家对病因病机、治则治法、针灸及其他疗法、预防调护条目重要性达成共识。证候特点删除了与证型相关度低或引起歧义的要素,代表方删除现代已弃用或同名异方。同时,对证型、治则治法的名称进行统一规范化处理。结论《脑卒中“病脉证并治”临床辅助决策方案》条目基本得到专家认同,但仍存在局限性,有待进一步研究探讨。

艾滋病（AIDS）病毒抗体检测方法研究进展

对艾滋病（ＡＩＤＳ）病毒抗体检测方法的研究进展作了较系统的评述。从抗原试剂的构成及样品的来源等方面对各种检测方法进行归纳分类。论述了病毒抗体检测方法研究发展的三个阶段，分析比较了各种艾滋病毒抗体检测方法的优缺点。给出１２５篇参考文献。

新疆昌吉州口腔修复学医疗援疆带教的实践与思考

医疗援疆在新时代党中央的治疆方略中具有重要的意义。福建医科大学附属口腔医院在对口医疗援助新疆昌吉回族自治州人民医院口腔科期间,围绕提高受援地口腔修复临床治疗以及科研水平的目的,针对新疆地区地域文化及口腔疾病发病特点,以临床问题为导向,通过师带徒结对带教,案例教学法(case-based learning,CBL)组织专题讲座培训,临床反馈式手术操作演示,立足临床基础培养提升受援科室的临床科研能力等方式,充分带动受援单位人员学习的主观能动性,养成自我学习、分析问题的习惯,从而达到为当地口腔修复学科构建人才培养体系,建设学科人才梯队,有效提升临床诊疗水平的目的,并为医疗援疆人才培养及学科建设提供示范借鉴作用,让医疗援疆真正实现由输血到造血的转变,留下一支带不走的人才队伍。

熵权TOPSIS法综合评价新疆教育发展

为了推动地区教育事业的高质量发展,从教育规模、教职工人数和学生规模3个维度选取和构建教育发展综合评价指标和体系,采用熵权TOPSIS法对新疆14个地(州、市)2008—2018年面板数据进行教育发展水平综合评价与实证分析,并根据综合评价结果探讨新疆各地区教育发展水平的不均衡现象。结果表明:新疆各地(州、市)的教育发展水平存在显著差异,其中昌吉回族自治州的教育发展水平排名逐渐好转,喀什地区的排名一直靠前,而博尔塔拉蒙古自治州的排名情况相当不理想;在考虑教育援疆给新疆教育发展带来显著成效的同时,教育援疆政策的进一步实施应兼顾地区教育的均衡发展和教育资源的合理配置。

智能时代家电产品创新设计方法发展趋势研究

本文探讨了智能时代背景下家电产品创新方法的发展趋势,强调集成智能功能的创新设计工具是计算辅助创新设计(CAI)发展的重要趋势。提出了将场景数据库、用户画像数据、用户画像产品定制化分析以及在线评论数据挖掘等功能集成入以TRIZ/ARIZ为模型主体的计算机辅助创新设计软件中,还探讨了构建场景数字孪生模型与CAI系统的集成方式,以及如何利用人工智能技术结合家电辅助创新CAI软件来推动家电产品设计的创新。这些内容展望了利用先进技术提升家电设计效率和创新性的可能性。

MCAT教学法在美容机构医护人员急救能力培训中的应用

目的探讨MCAT教学法在民营医疗美容机构医护人员急救能力培训中的应用效果。方法将民营医疗美容机构医护人员作为研究对象,培训前对医护人员进行摸底考核,采用MCAT教学法进行急救能力培训后对其进行考核,对比培训前后医护人员考核成绩及自我效能感。结果培训后民营医疗美容机构医生、护士、药师及检验人员考核成绩明显提高,医护人员心肺复苏、简易呼吸器及电除颤相关知识回答正确率明显提高,一般自我效能感量表得分比较差异有统计学意义(P<0.05)。结论MCAT教学法在民营医疗美容机构医护人员急救能力培训中的应用效果较好,能明显提升医护人员急救水平、应对临床意外事件的信心及培训满意度,值得推广。