Awareness, Practice and Intention to Practice Testicular Self-Examination among Professional Working Males in Ghana

Background: The aetiology of Testicular Cancer (TC) is still unknown to researchers but many of the associated risk factors have been identified. These include family history, age, racial origin, cryptorchidism, urogenital malformations, testicular atrophy, and infertility. Given the lack of scientific data on the causes of the disease, it has been asserted in previous studies that the promotion of awareness and early detection are prerequisites to mitigating risks of metastasis as well as improving survival. This study is to assess the awareness, practice, and intention to practice testicular self-examination among professional working males in Accra. Methods: A quantitative cross-sectional design with a structured research instrument was used to collect data from respondants. The purposive and convenience sampling techniques were used to collect data from 300 men at Accra in Ghana. The study was conducted at two (2) Universities and a Senior High school at Accra in Ghana. The data was then analysed using descriptive statistics, logistic regression, multiple linear regression, and structural equation modeling. Results: From the study findings, 37% of male participants rated their knowledge of testicular self-examination and related symptoms as good, 28% of participants practised testicular self-examination monthly, while 65% of respondents expressed their intention to practice monthly testicular self-examination. The findings from logistic regression demonstrated that level of education, age, and marital status of participants had a significant influence on testicular self-examination. Additionally, the multiple linear regression results revealed knowledge and self-efficacy significantly predict testicular self-examination intention. The path coefficient results from the structural equation model are consistent with results from the regression models. Conclusion: This research is the first to investigate testicular self-examination among men in Ghana. The findings revealed awareness and practice of TSE are low among participants. Therefore, the research findings would improve the expertise of physicians and nurses in providing counsel, intervention, and support for patients at risk of testicular cancer.

The Association of Mercury and ALT with Obesity in Korean Adults Using Data from the Korea National Health and Nutrition Examination Survey for 11 Years(KNHANES 2005,2008-2017)

The association between heavy metals in the blood and obesity has been examined in many studies.However,inconsistencies have been observed in the results of these studies.The present study was conducted using data from 119,181 participants of the Korea National Health and Nutrition Examination Survey(KNHANES)for 11 years in 2005 and between 2008 and 2017.The subjects with missing heavy metal blood tests,health interview data,and health examination data were excluded from the study.The study population comprised 1,844 individuals(972 men,and 872 women)who were eligible for inclusion.It was found that obesity and abdominal obesity were associated with an increase in both blood mercury(P<0.001)and alanine aminotransferase(ALT)(P<0.001).After adjusting the confounding factors,those with concurrent high levels of ALT and the highest tertile of mercury showed an increased risk of obesity(odds ratio 4.46,95%confidence interval 2.23-8.90,P<0.001)as well as abdominal obesity(odds ratio 5.36,95%confidence interval 2.57-11.17,P<0.001).The interrelationship of mercury and ALT with the parameters of body mass index(P for interaction=0.009)and waist circumference(P for interaction=0.012),respectively,have been observed to be significant,suggesting that the reciprocal relationship could contribute to obesity and abdominal obesity.

Low skeletal muscle mass is associated with non-alcoholic fatty liver disease in Korean adults： the Fifth Korea National Health and Nutrition Examination Survey

BACKGROUND： Sarcopenia and non-alcoholic fatty liver dis- ease （NAFLD） share similar pathophysiological mechanisms, and the relationship between sarcopenia and NAFLD has been recently investigated. The study investigated whether low skel- etal muscle mass is differentially associated with NAFLD by gender in Korean adults. METHODS： We conducted a cross-sectional analysis of the data from the Fifth Korea National Health and Nutrition Examination Survey. The skeletal muscle index （SMI） was obtained by the appendicular skeletal muscle mass divided by the weight. NAFLD was defined as a fatty liver index （FLI） 〉60 in the absence of other chronic liver disease. RESULTS： Among the included subjects, 18.3% （SE： 1.4%） in men and 7.0% （SE： 0.7%） in women were classified as having FLI-defined NAFLD. Most of the risk factors for FLI-defined NAFLD showed a significant negative correlation with the SMI in both genders. Multiple logistic regression analysis showed that low SMI was associated with FLI-defined NAFLD, inde- pendent of other metabolic and lifestyle parameters in both genders [males： odds ratio （OR）=1.35; 95% confidence inter- val （CI）： 1.17-1.54; females： OR=1.36; 95% CI： 1.18-1.55]. The magnitude of the association between FLI-defined NAFLD and low SMI was higher in middle aged to elderly males （OR-1.50; 95% CI： 1.22-1.84） than in males less than 45 years of age （OR=1.25; 95% CI： 1.02-1.52） and in premenopausal females （OR=l.50; 95% CI： 1.12-2.03） than in postmenopausal females （OR-1.36; 95% CI： 1.20-1.54）.CONCLUSIONS： Low SMI is associated with the risk of FLI- defined NAFLD independent of other well-known metabolic risk factors in both genders. This association may differ ac- cording to age group or menopausal status. Further studies are warranted to confirm this relationship.

An enrichment model using regular health examination data for early detection of colorectal cancer

Objective: Challenges remain in current practices of colorectal cancer(CRC) screening, such as low compliance,low specificities and expensive cost. This study aimed to identify high-risk groups for CRC from the general population using regular health examination data.Methods: The study population consist of more than 7,000 CRC cases and more than 140,000 controls. Using regular health examination data, a model detecting CRC cases was derived by the classification and regression trees(CART) algorithm. Receiver operating characteristic(ROC) curve was applied to evaluate the performance of models. The robustness and generalization of the CART model were validated by independent datasets. In addition, the effectiveness of CART-based screening was compared with stool-based screening.Results: After data quality control, 4,647 CRC cases and 133,898 controls free of colorectal neoplasms were used for downstream analysis. The final CART model based on four biomarkers(age, albumin, hematocrit and percent lymphocytes) was constructed. In the test set, the area under ROC curve(AUC) of the CART model was 0.88 [95%confidence interval(95% CI), 0.87-0.90] for detecting CRC. At the cutoff yielding 99.0% specificity, this model’s sensitivity was 62.2%(95% CI, 58.1%-66.2%), thereby achieving a 63-fold enrichment of CRC cases. We validated the robustness of the method across subsets of test set with diverse CRC incidences, aging rates, genders ratio, distributions of tumor stages and locations, and data sources. Importantly, CART-based screening had the higher positive predictive value(1.6%) than fecal immunochemical test(0.3%).Conclusions: As an alternative approach for the early detection of CRC, this study provides a low-cost method using regular health examination data to identify high-risk individuals for CRC for further examinations. The approach can promote early detection of CRC especially in developing countries such as China, where annual health examination is popular but regular CRC-specific screening is rare.

City Health Examination in China:A Methodology and Empirical Study

National urban planning,construction,and management levels have undergone qualitative changes in China since 2000.Nonetheless,problems caused by rapid urbanization are becoming increasingly prominent.The concept of the city health examination appears to tackle these problems and is being gradually implemented,starting from the implementation of a national strategy and leading to the concrete practice of high-quality urban development.This paper elaborates on the basic philosophy and theory of the city health examination,briefly explains indicator selection and aims,and comprehensively illustrates examination methods.It then describes the empirical research that operationalized the dataset collected from a satisfaction survey administered during the 2020 city health examination.It aims to provide a reference for the standardization,specialization,analysis,and application of the results of the city health examination in China;this may help promote a smooth elimination of‘urban diseases’and allow for the development of high-quality livable cities.This research shows that city residents are generally more satisfied with the landscape features,ecological livability,and security resilience;it also shows that residents are generally more dissatisfied with traffic issues.Residents with different characteristics showed different satisfaction levels toward different indicators.Residents were also shown to be more sensitive to innovation vitality,ecological livability,and health and comfort in considering whether to stay in their current city.

Regional Differences in Specific Health Examination Utilization and Medical Care Expenditures in Japan

Background: Despite having one of the most successful health systems in the world, annual medical expenditures in Japan have been increasing year to year. We sought to clarify regional differences in medical expenditures by analyzing the relationship between the specific health examination coverage and medical care expenditure by prefecture of Japan. Methods: We used data from the National Database of Health Insurance Claims and Specific Health Checkups (NDB) Open Data Japan (2015) and Overview of 2015 National Medical Expenses to compare medical care expenditure per capita and proportions of persons receiving specific health examination between Japan nationally and individual prefectures. Results: National medical expenditures were 42.3 trillion Japanese yen (JPY) (3851 hundred million dollars), with a national per capita rate of JPY347,219 (USD3156). Per capita medical expenditure rates by prefecture ranged from JPY290,900 (USD2645) in Saitama Prefecture to JPY 444,000 (USD4036) in Kochi Prefecture. The proportion of persons receiving specific health examinations was 49.0% for Japan overall and ranged from 39.3% in Hokkaido Prefecture to 63.4% in Tokyo Prefecture. We observed a significant negative correlation between per capita medical expenditures and the proportion of persons receiving specific health examinations (R = 0.553, p < 0.001). Conclusion: We found a significant negative correlation between per capita medical expenditures and the proportion of persons receiving health examinations: prefectures with lower expenditures tended to have higher rates of medical examinations. Interventions to increase the proportion of persons receiving specific health examinations by prefecture could reduce per capita medical expenditures and reduce prefectural disparities in expenditures.

Association of Health-related Quality of Life with Health Examination and Lifestyles of Government Managers in China

In order to study the association of each item of a health examination and lifestyles with health-related quality of life (HRQoL), a cross-sectional survey by a self-administered questionnaire using the 12-Item Short Form Health Survey (SF-12, version 1) was conducted on 145 government managers that took health examinations in Tongji Hospital, Wuhan, China during 2005. The results showed that the determinations of organic functions including BMI, hemoglobin, blood platelet count, urine protein, urine WBC and lipid metabolism (LDL) were associated with HRQoL. The lifestyle items including age, sex, life satisfaction, drinking alcohol and kind of alcohol drunk, drinking tea, sleep quality and adhering to bedtime, working overtime, work stress were associated with HRQoL in the multiple regression models. Sex, age and life satisfaction were the lifestyle items most closely associated with HRQoL, while LDL, hemoglobin and urine protein were the health examination items most closely associated HRQoL. This study revealed that both lifestyle and health examination items were associated with HRQoL.

Providing Physical and Mental Health Support Using Medical Examination Data and Perceived Health

Without ascertaining workers’ perceived health, it is difficult to achieve behavioral modification even if health guidance is conducted. To investigate physical and mental health support emphasizing “positive health,” we used the Total Health Index (THI) survey with the purpose of elucidating the association between medical examination data and perceived health. After obtaining medical examination data from 90 men, we analyzed their responses to the THI survey. The results suggested that age and abnormal medical examination data are associated with physical and mental complaints. In the analysis by age group, we found that men in their 20s had more complaints of irregularity of daily life on the THI scale. The group who responded that they were not getting enough sleep had higher mean values of total cholesterol and fasting blood sugar. The group who responded that their meals were irregular had higher mean values of Body Mass Index, aspartate aminotransferase, and alanine aminotransferase. As confirmed by the THI, continuously supporting lifestyle improvement is important. The THI of the “health guidance” group indicated fewer physical health complaints and more aggression/extroversion than the “normal” group. In those for whom health guidance was applicable, participants who were “obese” and “hypertensive” had more aggression/extroversion and lesser extent of nervousness. Based on these findings, it was suggested that meaningful, personalized health support can be developed.

Analysis of health examination results of 774 policemen in a city of Hainan Province

Objective: To understand the health status of policemen in a city of Hainan Province, and find out the potential risk factors influencing their health. Methods: Health examination data of 774 policemen was collected, analyzed, and compared between age-groups, gender-groups and marital status-groups by using luster sampling. Results: 760 policemen had at least one abnormal examination (98.19%). The highest abnormality rate was blood lipid examination with 582 persons (75.19%), the second was liver function examination with 433 persons (55.94%), the third was body mass index-examination with 385 persons (49.74%). Among 15 examination items, 10 items in men had higher abnormal rate than those in women;11 items were statistically significant different among three age-groups;4 items in married had higher abnormal rate than those in unmarried. Conclusion: The health condition of policemen in a city of Hainan Province is not so optimistic, the main risk to health comes from lifestyle, and women are in better health condition than men. The older the police are, the worse they are.

Analysis of risk factors for polypoid lesions of gallbladder among health examinees

AIM: To investigate the prevalence and risk factors of polypoid lesions of gallbladder (PLG) among the health examinees in the Shanghai region, China. METHODS: A total of 11 816 subjects who underwent health examinations in our hospital between August 2010 and February 2011 were analyzed retrospectively. Among them, there were 7174 men and 4642 women. PLG was diagnosed by the real-time ultrasonography. Those with the body mass index (BMI) ≥ 28 were considered to be obese. Blood biochemical indices were detected with the fully automatic biochemical analyzer and hepatitis B surface antigen (HBsAg) was tested by the automated enzyme immunoassay. The correlations between the prevalence of PLG and age, sex, BMI, serum cholesterol (T-Cho), triglycerides (TG),blood sugar, HBsAg, high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), gallstone and fatty liver were investigated. After univariate analysis of 11 variables, stepwise logistic regression analysis was performed to explore the risk factors of PLG. RESULTS: There was a significant difference in sex, T-Cho, HBsAg, HDL-C, LDL-C and fatty liver between the PLG-positive group and the PLG-negative group (332/163 vs 6842/4479, P = 0.003; 22/473 vs 295/11 026, P =0.013; 92/403 vs 993/10 328, P = 0.001; 47/448 vs 332/10 989, P = 0.001; 32/463 vs 381/10 940, P = 0.001; 83/412 vs 3260/8061, P = 0.001). No significant difference was found in the age, BMI, TG, blood sugar and gallstone between the two groups (47.3 ± 26 vs 45.1 ± 33, P = 0.173; 59/436 vs 1097/10 224, P = 0.102; 52/443 vs 982/10 339, P = 0.158; 17/478 vs 295/11 026, P = 0.26; 24/471 vs 395/10 926, P = 0.109). Logistic regression analysis showed that the sex, HBsAg and HDL-C were independent risk factors for the development of PLG in a descending order of HDL-C > HBsAg > sex. CONCLUSION: In healthy people, the male gender, positive HBsAg, and low HDL-C confer higher risks of PLG development.

Survey on Pre-pregnancy Health Knowledge and Service Demands among Un-pregnant Married Women

Objective To understand the pre-pregnancy health knowledge and service needs among un-pregnant married women in Shanghai. Methods A total of 968 newly-married un-pregnant women in Changqiao, Lingyun sub-districts and Huajing town of Xuhui district, Shanghai, were recruited and interviewed by structured questionnaire to collect the information on pre-pregnancy health knowledge and service demands. Results 1） Newly-married women thought the contraceptive methods suitable for them was male condom（84.4%）, followed by oral contraceptives（54%）, emergent contraceptive（52.5%） and contraceptive suppository （48.3%）. 2） The score of pre-pregnancy health knowledge was 54.7±14.5 among the subjects. The participants with junior college or a bachelor had more knowledge than those with junior or senior high school, and those who were engaged in medicine /education/science field had higher score. 3） They had higher knowing rate on the common knowledge, and the rate was above 80%. But the knowing rate on the knowledge of birth defect was low, and all below 50%. 4）A proportion of 52. 7% of the respondents knew that there was a station for reproductive health service in their communities, but only 45.5% received the service from the station, 87.0% thought they had insufficient or scarce knowledge, 73.6% planned to consult before pregnancy training courses on preparing pregnancy. and 63.6% were willing to attend the Conclusion The participants had certain pre-pregnancy health knowledge, but still need being improved,＂ in addition, they had higher needs on knowledge and service of birth defect prevention, at the same time they can＇t make full use of the existing reproductive health institution.

健康体检人群甲状腺结节检出情况及发病的影响因素

目的调查健康体检人群甲状腺结节(TNs)检出情况,并分析其影响因素,为早期防治TNs提供参考依据。方法选取2022年1月1日至2023年4月30日15393例健康体检人群,均进行多普勒超声检查,按年龄分层及性别统计TNs患病率,通过单因素及多因素logistic回归方程分析TNs影响因素。结果15393例健康体检者,共检查出5001例TNs,检出率为32.49%(5001/15393)。男性不同年龄组TNs检出率均低于女性(P<0.05)。健康人群随着年龄增长TNs检出率呈升高趋势(P<0.05)。两组体重指数、收缩压、舒张压、空腹血糖(FPG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、性别、年龄、吸烟、饮酒、高脂血症、糖尿病、代谢综合征、脂肪肝、焦虑、抑郁比较,差异有统计学意义(P<0.05)。年龄、性别、糖尿病、脂代谢综合征、脂肪肝、焦虑、抑郁均为TNs独立影响因素(P<0.05)。结论健康体检人群TNs检出率较高,主要与年龄、性别、糖尿病、脂代谢综合征、脂肪肝、焦虑、抑郁等因素有关,临床应在健康体检中普及甲状腺彩超检查项目,以实现对甲状腺疾病的尽早防治。

0~6岁儿童眼保健和视力检查服务现状及对策研究

目的了解0~6岁儿童眼保健和视力检查服务现状,为相关部门提供决策依据。方法采用方便抽样方法,于2019年9—12月从北京市、安徽省、青海省抽取15家区县级妇幼保健院及基层卫生机构进行问卷调查,并采用现场观察及小组访谈的方式了解儿童眼保健服务现状及存在的问题等。结果被调查的区县级妇幼保健机构均配备了开展儿童眼保健服务的基本用房及设备;基层卫生机构均配备了开展儿童眼保健服务的基础设备,但有些设备陈旧破损、闲置未用。被调查机构儿童眼保健人员均不足,区县级妇幼保健院、社区卫生服务中心和乡镇卫生院的儿童眼保健人员分别占卫生技术人员的9.5%、5.5%和2.4%,不同类型卫生机构的儿童眼保健人员占比差异有统计学意义(χ^(2)=8.966,P=0.011)。社区卫生服务中心无眼科医生,该岗位由儿保人员兼职。被调查机构儿童眼保健人员接受上级指导及培训的机会普遍较少,年人均1~3次。各地儿童眼保健及视力检查服务覆盖率均在90%以上,但现场观察发现儿童眼保健人员操作技能尚不熟练、不规范。结论各卫生机构均需进一步完善儿童眼保健及视力检查服务设备,提高儿童眼保健人员的知识技能及服务质量。

基于岗位分析与工时测定的医院健康体检(管理)中心护士人力资源配置研究

目的:构建医院健康体检(管理)中心护士人力资源配置方法,为完善健康体检(管理)中心的规范化管理提供指导。方法:通过文献回顾,利用岗位分析和工时测定相结合的方法,梳理北京市某三甲综合医院体检中心主要8项护士岗位工作。其中不以流程作业方式运行的岗位包括护士长岗位、体检服务台、市场外联岗位;以流程作业方式运行的静脉采血、心电图等岗位,采用工时测定法计算该院健康体检中心2023年11月至2024年1月各岗位完成每次检查所需工时,并推算所需护士数。结果:结合岗位分析与工时测定,测算该院体检中心护士人力合理配置应为20人。结论:根据研究结果,该体检中心调整护士配置人数,有效提高了体检工作质量与人员工作效率,为其他医院健康体检(管理)中心护士人力资源合理配置提供了有益的借鉴,对推动健康体检规范化管理具有重要意义。

基于微信公众平台的自助服务系统在预防性健康检查的应用效果

目的分析评价基于微信公众平台的自助服务系统在从业人员预防性健康检查的应用效果。方法将2021年1—6月在红谷滩区预防医学门诊部进行预防性健康检查的4768名从业人员和2022年1—6月在该门诊部进行预防性健康检查的4544名从业人员分别作为对照组和观察组。对照组的健康检查通过线下预约、在纸质表登记体检结果和人工核验后反馈结果等传统流程进行,观察组使用基于微信平台的自助服务系统进行健康检查,通过线上分时段预约、身份证读取信息、电脑端录入体检结果、系统自动核验及微信反馈结果等流程进行。记录并比较两组健康检查各环节消耗时间、检查信息完整率和准确率以及服务满意度评分。结果和对照组相比,观察组在信息录入、排队等待、检查全过程和检查后结果反馈环节消耗的时间更少(P<0.05);观察组健康检查数据完整率和准确率均高于对照组(均P<0.05);观察组在结果获取及时、检查结果防伪性、流程公正及现场秩序的满意度评分均高于对照组(均P<0.05)。结论基于微信平台的自助服务系统有助于提高预防性健康检查工作效率和服务质量,提升从业人员对体检机构的满意度。

老年结直肠癌高危人群智能语音健康干预效果评价

目的评价60岁及以上结直肠癌高危人群智能语音健康干预效果,为提高该人群知识水平和检查行为依从性提供依据。方法将2020年上海市黄浦区社区60岁及以上居民结直肠癌筛查项目中初筛结果为阳性者782例使用随机数字表法分为干预组和对照组。在1年干预期间,干预组接受2次智能语音电话干预,对照组接受常规健康教育。在干预前后,分别对干预组和对照组进行一次问卷调查,了解其结直肠癌防治的相关知识以及肠镜检查和肛指检查行为改变情况。结果干预组344例,对照组342例,2组对象一般资料比较,差异均无统计学意义(P>0.05)。干预后,干预组较对照组的大肠癌防治知识总分高0.29分,且差异有统计学意义(χ^(2)=5.45,P<0.05),干预组干预后较干预前知识总分提高了0.55分且差异有统计学意义(χ^(2)=60.84,P<0.05)。干预后,干预组的肠镜检查率显著高于对照组(χ^(2)=4.24,P<0.05),干预组干预后较干预前肠镜率显著提高,且差异有统计学意义(χ^(2)=28.25,P<0.05)。结论运用智能语音技术对60岁及以上结直肠癌高危人群进行干预是提高大肠癌防治知识和肠镜检查率的有效手段,可在今后的干预项目中进一步完善和推广。

全流程健康体检管理系统的设计与应用

目的解决体检管理系统信息孤岛问题,探索标准化、规范化的体检管理系统建设路径。方法健康体检管理系统设计依照体检业务检前、检中与检后流程设计,根据医院信息系统的医嘱字典定义体检检查项目名称与代码,利用主索引技术,通过医院集成平台直接从主数据的生产系统获取数据,实现临床数据与体检数据共享。结果该系统实现了体检者健康体检数据的互联互通及标准化管理,兼具终末管理及过程监督管理的需求。系统的应用有效降低了各体检套餐的开单耗时、缴费耗时与体检环节耗时,且差异均有统计学意义(P<0.05);显著提升了体检医生满意度(P<0.001),符合体检中心人员对系统的期望值。结论该系统的设计与应用改进了现有健康管理服务模式,有利于系统向分院区辐射与推广。

基于健康体检人群分析青年骨量异常的现状及影响因素

目的分析北京市参加健康体检人群中的青年骨量异常患者的特点及影响因素,为骨量减少和骨质疏松的防治提供依据和参考。方法收集2023年1-7月在首都医科大学附属北京友谊医院健康体检行骨密度检查且年龄≤40岁人群共973人,其中,骨量异常青年人群348人,骨量正常青年人群625人,选取潜在相关指标分析青年体检人群的骨量异常发生情况及可能影响因素。结果青年体检人群骨量异常发生率为35.77%,其中,骨量减少人群占91.67%,骨质疏松症人群占8.33%,男性占57.47%,女性占42.53%。通过单变量分析,骨量异常的发生与多种因素有关,包括性别、年龄、体重、身体质量指数、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血尿酸,吸烟与饮酒等(P<0.05);进一步的多变量Logistic回归分析表明,年龄(OR=1.045)、较低的身体质量指数(OR=0.761)、甘油三酯(OR=2.828)、血尿酸(OR=1.007)、饮酒(OR=5.238)、吸烟(OR=1.853)是发生骨量异常的危险因素(P<0.05)。结论青年人群骨量减少和骨质疏松检出率呈上升趋势,应重视健康体检,并积极进行骨密度早期筛查。

高职公共卫生人才实践技能教学提升探究——基于公共卫生执业(助理)医师考试

为了探讨提升高职预防医学专业公共卫生实践技能的方法,帮助学生提升公共卫生实践能力,提高公共卫生执业医师资格证的考试通过率,采用文献查阅、学生调研等方法,找出实训教学困境,并提出优化课程设置、加强实践教学、创新教学方法以及加强“双师型”教师制度等提升措施,进行教学改革实践。经过教学改革后,学生反映公共卫生各项技能掌握程度比较好,对公共卫生执业(助理)医师考试实践部分更有信心。由此可知,预防医学专业学生公共卫生实践技能培养对学生的意义重大,既可以提高学生的实践操作能力,让学生对实习阶段的学习更加游刃有余,也能提升公共卫生执业医师资格证的考试通过率,值得进一步推广。

某医院对健康体检人群尿酸水平及其影响因素的分析

目的分析某医院健康体检人群尿酸水平及其影响因素。方法选取2012年1月—2022年1月在本院接受尿酸检测的健康体检人员39211名为研究样本,根据诊断结果分为两组,其中诊断为高尿酸血症患者为高尿酸血症组(5685例),其他为尿酸正常组(33526例),比较尿酸正常组与高尿酸血症组体检者的基线资料,分析影响高尿酸血症发生的危险因素。结果在健康体检者中,相较于尿酸正常组,高尿酸血症组患者的血压、体质量指数、总胆固醇、血糖、三酰甘油的水平与动脉粥样硬化发生率均更高(P<0.05);但在年龄、肌酐和尿素氮方面,组间差异无统计学意义(P>0.05);Logistic回归分析显示,体质量指数、血糖、总胆固醇、三酰甘油的水平与动脉粥样硬化发生率为影响健康体检人群尿酸水平的独立危险因素(P<0.05)。结论健康体检人群尿酸水平的升高和机体血糖、总胆固醇、体质量指数、三酰甘油的水平存在明显的关联,尿酸水平升高是促使动脉粥样硬化发生率提升的重要因素。