Pregnancy complicating fulminant hepatitis is characterized by rapid progress, complicated clinical symptoms, and association with blood coagulation dysfunction, hepatic encephalopathy, hepatorenal syndrome, toxic ent...Pregnancy complicating fulminant hepatitis is characterized by rapid progress, complicated clinical symptoms, and association with blood coagulation dysfunction, hepatic encephalopathy, hepatorenal syndrome, toxic enteroparalysis and infection. Late pregnancy complicating fulminant hepatitis, which has a high fatality rate, is one of the maior causes of death of gravida and puerperant in China. Searching for exact objective indexes and correct judgement of the prognosis is extremely important to clinical work. The indexes of liver function mainly include (1) indexes for the damage of hepatic cells and its degree such as alanine transaminase (ALT), etc; (2) indexes for the synthesis function of hepatic cells such as albumin (ALB), total cholesterol (CHOL), prothrombin time (PT), prothrombin activity (PTA), etc; (3) indexes for the function of liver excretion, metabolism and detoxication such as total bilirubin (TBIL), total bile acid (TBA), blood ammonia (NH3), etc.展开更多
Fulminant hepatitis (FH) refers to liver diseases that have severe state and complicated manifestations. It will endanger patients'lives and health largely. The incidence of fulminant hepatitis in pregnancy (FHP)...Fulminant hepatitis (FH) refers to liver diseases that have severe state and complicated manifestations. It will endanger patients'lives and health largely. The incidence of fulminant hepatitis in pregnancy (FHP) is 66 times of patients not in pregnancy,1 which is more dangerous and is one of the major causes of maternal and perinatal death in China. In order to predict the prognoses of FHP and decrease maternal and perinatal death rate, we summarized clinical information of 25 cases of FHP admitted to our hospital and investigated into prognostic factors that influenced FHP.展开更多
基金This study was supported by grants from the Technological Project of Guangdong Province(No.2005B340201006)the Bureau of Traditional Chinese Medicine and Drugs of Guangdong Province(No.1060166)
文摘Pregnancy complicating fulminant hepatitis is characterized by rapid progress, complicated clinical symptoms, and association with blood coagulation dysfunction, hepatic encephalopathy, hepatorenal syndrome, toxic enteroparalysis and infection. Late pregnancy complicating fulminant hepatitis, which has a high fatality rate, is one of the maior causes of death of gravida and puerperant in China. Searching for exact objective indexes and correct judgement of the prognosis is extremely important to clinical work. The indexes of liver function mainly include (1) indexes for the damage of hepatic cells and its degree such as alanine transaminase (ALT), etc; (2) indexes for the synthesis function of hepatic cells such as albumin (ALB), total cholesterol (CHOL), prothrombin time (PT), prothrombin activity (PTA), etc; (3) indexes for the function of liver excretion, metabolism and detoxication such as total bilirubin (TBIL), total bile acid (TBA), blood ammonia (NH3), etc.
文摘Fulminant hepatitis (FH) refers to liver diseases that have severe state and complicated manifestations. It will endanger patients'lives and health largely. The incidence of fulminant hepatitis in pregnancy (FHP) is 66 times of patients not in pregnancy,1 which is more dangerous and is one of the major causes of maternal and perinatal death in China. In order to predict the prognoses of FHP and decrease maternal and perinatal death rate, we summarized clinical information of 25 cases of FHP admitted to our hospital and investigated into prognostic factors that influenced FHP.