BACKGROUND The vaginal microbiome plays a critical role in the health of pregnant women and their newborns.Group B Streptococcus(GBS)and vaginal cleanliness significantly affect the vaginal microecosystem and are clos...BACKGROUND The vaginal microbiome plays a critical role in the health of pregnant women and their newborns.Group B Streptococcus(GBS)and vaginal cleanliness significantly affect the vaginal microecosystem and are closely associated with vaginal diseases.AIM To explore the effects of GBS status and vaginal cleanliness on vaginal microecosystems.METHODS We collected 160 vaginal swabs from pregnant women and divided them into the following four groups based on GBS status and vaginal cleanliness:GBS-positive+vaginal cleanliness I–II degree,GBS-negative+vaginal cleanliness I–II degree,GBS-positive+vaginal cleanliness III–IV degree,and GBS-negative+vaginal cleanliness III–IV degree.Samples were subjected to 16S rRNA gene amplicon sequencing.RESULTS Alpha diversity analysis showed that the Shannon index did not significantly differ between the four groups.We identified significant variation in taxa abundance between the GBS-positive and GBS-negative groups and between the vaginal cleanliness I–II degree and III–IV degree groups.Principal coordinate analysis and non-metric multidimensional scaling analysis further confirmed the microbial diversity of the four groups.Moreover,the linear discriminant analysis demonstrated that Lactobacillus jensenii and Actinobacteria were strongly associated with GBS-positive status,and Lactobacillus iners,Lactobacillaceae,Lactobacillus,Lactobacillales,Bacilli and Firmicutes were closely correlated with GBS-negative status.CONCLUSION GBS status and vaginal cleanliness significantly affect vaginal microbiome differences in pregnant women.Our findings provide instructional information for clinical antibiotic treatment in pregnant women with different GBS statuses and vaginal cleanliness degrees.展开更多
Postmodern cultural school makes a deep exploration of women's social roles and values from the perspective of human beings' social naturalness,culture and social function,conducts deep introspection on women&...Postmodern cultural school makes a deep exploration of women's social roles and values from the perspective of human beings' social naturalness,culture and social function,conducts deep introspection on women's social status from both macro and micro levels and carries out a brand newinterpretation of the impetus effect of critical thinking on women's social development. Postmodern cultural school overthrows the definitions and viewpoints expressed in traditional social constructivism and power theory by other cultural schools,explaining objectively the measuring standards of women's social status and refuting male chauvinism,thus promoting newattention to be paid to women's equality in social status.展开更多
THE year 1898 is worth remembering for China’ s women. It was that year that a large group of women who advocated social change established the Women’s Association for Progress, the Women’s School of China and star...THE year 1898 is worth remembering for China’ s women. It was that year that a large group of women who advocated social change established the Women’s Association for Progress, the Women’s School of China and started the first women’s newspaper, "Chinese Girl’s Progress" in Guishuli, Shanghai, with the support and participation of the reformers during the latter part of the Qing Dynasty. The article "On Equality展开更多
文摘BACKGROUND The vaginal microbiome plays a critical role in the health of pregnant women and their newborns.Group B Streptococcus(GBS)and vaginal cleanliness significantly affect the vaginal microecosystem and are closely associated with vaginal diseases.AIM To explore the effects of GBS status and vaginal cleanliness on vaginal microecosystems.METHODS We collected 160 vaginal swabs from pregnant women and divided them into the following four groups based on GBS status and vaginal cleanliness:GBS-positive+vaginal cleanliness I–II degree,GBS-negative+vaginal cleanliness I–II degree,GBS-positive+vaginal cleanliness III–IV degree,and GBS-negative+vaginal cleanliness III–IV degree.Samples were subjected to 16S rRNA gene amplicon sequencing.RESULTS Alpha diversity analysis showed that the Shannon index did not significantly differ between the four groups.We identified significant variation in taxa abundance between the GBS-positive and GBS-negative groups and between the vaginal cleanliness I–II degree and III–IV degree groups.Principal coordinate analysis and non-metric multidimensional scaling analysis further confirmed the microbial diversity of the four groups.Moreover,the linear discriminant analysis demonstrated that Lactobacillus jensenii and Actinobacteria were strongly associated with GBS-positive status,and Lactobacillus iners,Lactobacillaceae,Lactobacillus,Lactobacillales,Bacilli and Firmicutes were closely correlated with GBS-negative status.CONCLUSION GBS status and vaginal cleanliness significantly affect vaginal microbiome differences in pregnant women.Our findings provide instructional information for clinical antibiotic treatment in pregnant women with different GBS statuses and vaginal cleanliness degrees.
文摘Postmodern cultural school makes a deep exploration of women's social roles and values from the perspective of human beings' social naturalness,culture and social function,conducts deep introspection on women's social status from both macro and micro levels and carries out a brand newinterpretation of the impetus effect of critical thinking on women's social development. Postmodern cultural school overthrows the definitions and viewpoints expressed in traditional social constructivism and power theory by other cultural schools,explaining objectively the measuring standards of women's social status and refuting male chauvinism,thus promoting newattention to be paid to women's equality in social status.
文摘THE year 1898 is worth remembering for China’ s women. It was that year that a large group of women who advocated social change established the Women’s Association for Progress, the Women’s School of China and started the first women’s newspaper, "Chinese Girl’s Progress" in Guishuli, Shanghai, with the support and participation of the reformers during the latter part of the Qing Dynasty. The article "On Equality
