[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A to...[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A total of 200 pregnant women with normal pregnancy and frequent premature contractions who were treated in the outpatient department of internal medicine in Women and Children's Hospital of Hubei Province and Xinzhou District People's Hospital of Wuhan Central Hospital during September 2015 and October 2018 were selected and randomly divided into the control group and observation group,100 cases for each group.The observation group was treated with Danshen Injection combined with phosphocreatine disodium,and the control group was treated with phosphocreatine disodium alone.The course of treatment in both groups was one week.During the treatment,the changes of heart rate,heart rhythm,electrocardiogram and 24-h dynamic electrocardiogram(DCG)of both groups were observed.[Results]After treatment,the clinical efficacy of the observation group was better than that of the control group,and the difference was statistically significant(P<0.01).There were no adverse drug reactions in both groups.However,in the control group,non-sustained ventricular tachycardia(NSVT)was found in 24-h dynamic electrocardiogram(DCG)of 2 pregnant women with premature ventricular contraction.The pregnancy process was smooth,with full-term natural delivery and no fetal malformation.There was no significant difference in gestational age and neonatal weight between the two groups(P>0.05).However,there was a statistically significant difference in Apgar score between the two groups(P<0.05).During the 6-month postpartum follow-up,the mother and child were unharmed,and examination of repeated electrocardiograms showed that the conditions were normal.[Conclusions]Danshen Injection combined with phosphocreatine disodium has better efficacy in the treatment of frequent premature contractions during pregnancy and the maternal and infant outcomes than the treatment with phosphocreatine disodium alone,and it has good safety and can prevent premature contractions from progressing to tachyarrhythmias.展开更多
目的观察产时超声联合Kielland’s产钳在第二产程中的应用效果。方法选取2020年8月至2022年8月在湖州市妇幼保健院进行足月分娩的产妇350例进行回顾性分析,根据应用超声辅助Kielland’s产钳助产情况,分为观察组(n=242)和对照组(n=108)...目的观察产时超声联合Kielland’s产钳在第二产程中的应用效果。方法选取2020年8月至2022年8月在湖州市妇幼保健院进行足月分娩的产妇350例进行回顾性分析,根据应用超声辅助Kielland’s产钳助产情况,分为观察组(n=242)和对照组(n=108)。观察组在第二产程中应用超声辅助Kielland’s产钳进行助产分娩,对照组进行二程剖宫产。比较两组产妇和新生儿的并发症情况,包括产妇产后出血、绒毛膜羊膜炎、产后尿潴留、产后发热等,以及新生儿窒息和新生儿重症监护病房(neonatal intensive care unit,NICU)入住情况。结果观察组的产后出血、绒毛膜羊膜炎及住院天数均低于对照组,产后尿潴留发生率高于对照组,差异均有统计学意义(P<0.05);两组的新生儿NICU入住率及窒息率比较,差异均无统计学意义(P>0.05)。结论产时超声联合辅助Kielland’s产钳分娩,不仅不增加产妇或新生儿不良妊娠结局的发生,反而可以实现阴道助产,改善分娩结局,降低剖宫产率。展开更多
基金the Project of National Natural Science Foundation of China(81370337&81970331).
文摘[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A total of 200 pregnant women with normal pregnancy and frequent premature contractions who were treated in the outpatient department of internal medicine in Women and Children's Hospital of Hubei Province and Xinzhou District People's Hospital of Wuhan Central Hospital during September 2015 and October 2018 were selected and randomly divided into the control group and observation group,100 cases for each group.The observation group was treated with Danshen Injection combined with phosphocreatine disodium,and the control group was treated with phosphocreatine disodium alone.The course of treatment in both groups was one week.During the treatment,the changes of heart rate,heart rhythm,electrocardiogram and 24-h dynamic electrocardiogram(DCG)of both groups were observed.[Results]After treatment,the clinical efficacy of the observation group was better than that of the control group,and the difference was statistically significant(P<0.01).There were no adverse drug reactions in both groups.However,in the control group,non-sustained ventricular tachycardia(NSVT)was found in 24-h dynamic electrocardiogram(DCG)of 2 pregnant women with premature ventricular contraction.The pregnancy process was smooth,with full-term natural delivery and no fetal malformation.There was no significant difference in gestational age and neonatal weight between the two groups(P>0.05).However,there was a statistically significant difference in Apgar score between the two groups(P<0.05).During the 6-month postpartum follow-up,the mother and child were unharmed,and examination of repeated electrocardiograms showed that the conditions were normal.[Conclusions]Danshen Injection combined with phosphocreatine disodium has better efficacy in the treatment of frequent premature contractions during pregnancy and the maternal and infant outcomes than the treatment with phosphocreatine disodium alone,and it has good safety and can prevent premature contractions from progressing to tachyarrhythmias.
文摘目的观察产时超声联合Kielland’s产钳在第二产程中的应用效果。方法选取2020年8月至2022年8月在湖州市妇幼保健院进行足月分娩的产妇350例进行回顾性分析,根据应用超声辅助Kielland’s产钳助产情况,分为观察组(n=242)和对照组(n=108)。观察组在第二产程中应用超声辅助Kielland’s产钳进行助产分娩,对照组进行二程剖宫产。比较两组产妇和新生儿的并发症情况,包括产妇产后出血、绒毛膜羊膜炎、产后尿潴留、产后发热等,以及新生儿窒息和新生儿重症监护病房(neonatal intensive care unit,NICU)入住情况。结果观察组的产后出血、绒毛膜羊膜炎及住院天数均低于对照组,产后尿潴留发生率高于对照组,差异均有统计学意义(P<0.05);两组的新生儿NICU入住率及窒息率比较,差异均无统计学意义(P>0.05)。结论产时超声联合辅助Kielland’s产钳分娩,不仅不增加产妇或新生儿不良妊娠结局的发生,反而可以实现阴道助产,改善分娩结局,降低剖宫产率。
